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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - Option 4: Mathematically Adjust “Naïve” Estimates
The fourth option would most likely require expert statistical … Analysis option 4 requires expert statistical help. … Keep in mind that expert statistical help may be needed for analysis option 4 and that there is no evidence … This may require expert statistical help.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
July 01, 2012 - 1
Comparative Effectiveness Review
Number 68
Noninvasive Positive-Pressure
Ventilation (NPPV) for Acute
Respiratory Failure
Executive Summary
Background
Acute respiratory failure is a life-
threatening condition characterized by
an inability to maintain normal levels
of oxygen and/or carbon dioxide gas
exc…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - significant
geographical variations in the rate of diagnosis and treatment.1 The most recent Diagnostic and
Statistical … [Mesh] OR diagnosis[mesh:noexp] OR "Diagnostic Techniques
and Procedures"[Mesh] OR "Diagnostic and Statistical … graphical displays and test statistics (Q and I2 statistics), while
recognizing that the ability of statistical … Diagnostic and Statistical Manual of Mental
Disorders. 5th ed. … Manual of Mental Disorders, 4th Edition
DSM-5 Diagnostic and Statistical Manual of Mental Disorders
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
December 01, 2017 - Effectiveness and Safety of Bronchial Thermoplasty in Management of Asthma: Evidence Summary
Comparative Effectiveness Review
Number 202
Effectiveness and Safety of Bronchial Thermoplasty in
Management of Asthma
Evidence Summary
Objectives and Rationale for Review
This report summarizes a systematic
review, “E…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
January 01, 2007 - Data Synthesis
Given that many studies did not have the statistical power to determine equivalence … In the presence of statistical heterogeneity, we evaluated likely explanatory clinical and
methodological … When the results from statistical testing were similar,
we present the outcome that we judged to be … the proportion of patients achieving
successful blood pressure control on a single agent showed no statistical … enalapril
LVH (44-
53%)
RCT
N = 50
(42)
3 yr Fair LVMI Non-statistical ↓LVMI
both, no difference
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effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_chou_assessing_harms_when_comparing.pdf
November 01, 2008 - Drug approval information—for example, the clinical and statistical reviews prepared by
staff of the … drug reactions have been subjected to
rigorous evaluation in subsequent studies.
67
Nonetheless, statistical … In such cases, CERs should acknowledge the lack of statistical
power to assess risk adequately and … harms only when there are appropriate data to justify such
statements.
77
Few CERs will have the statistical … Statistical
combination of data from observational studies is often inappropriate and should be avoided
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_research-protocol.pdf
July 21, 2014 - by the American Psychiatric Association (APA) as a distinct eating disorder in the
Diagnostic and Statistical … Abbreviations: DSM = Diagnostic and Statistical Manual of Mental Disorders; LOC = loss of control
Epidemiology … If we conduct quantitative syntheses (i.e., meta-analysis), we will assess statistical
heterogeneity … If we include any meta-analyses with considerable
statistical heterogeneity in this report, we will … Diagnostic and Statistical Manual of Mental
Disorders. 5th ed., Arlington, VA: American Psychiatric
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research.pdf
June 01, 2017 - results, but we were unable to incorporate them in to the analysis, due to the
fact that they had no statistical … maximum follow up recorded; we also looked for differences in the
estimation procedure (the prescribed statistical … Again, the paper gave much more detail
and included statistical analyses not reported in the record, … we would
need hazard ratios to perform a meta-analysis and the record does not include any formal
statistical … No statistical analysis is
provided, and because these are the same treatment types (antibiotic and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-harms_methods.pdf
November 01, 2008 - Drug approval information—for example, the clinical and statistical reviews prepared by
staff of the … drug reactions have been subjected to
rigorous evaluation in subsequent studies.
67
Nonetheless, statistical … In such cases, CERs should acknowledge the lack of statistical
power to assess risk adequately and … harms only when there are appropriate data to justify such
statements.
77
Few CERs will have the statistical … Statistical
combination of data from observational studies is often inappropriate and should be avoided
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - www.effectivehealthcare.ahrq.gov
Published online: April 20, 2015 16
5.5 If N or PN to 5.1, 5.2 or 5.3: Were appropriate statistical … Statistical significance (will be set at a two
sided alpha of 0.05). … We will evaluate for statistical heterogeneity among studies using an I2 statistic, and anticipate
statistical … A value greater than 50% will be considered to have substantial
statistical heterogeneity. … For studies reporting on test performance outcomes, statistical analyses will be conducted using
methods
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_executive.pdf
April 28, 2010 - prevalence
of current dependence (within the last 12 months and as
defined by the Diagnostic and Statistical … The chi-squared statistic and the I2 statistic were calculated
to assess statistical heterogeneity in … Low
Utilization Emergency visits Difference between groups for visits in past 6 months did not reach statistical … TrEAT reported a lower number of days
of hospitalization for the intervention group that did not reach statistical … Diagnostic and statistical
manual of mental disorders, 4th ed. Text rev.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-disposition-comments.pdf
November 07, 2023 - Peer Reviewer #1 Methods The methods seem appropriate, including the inclusion/exclusion criteria and
statistical … Statistical methods, including
descriptions of when statistical (quantitative) vs. qualitative analysis … Public Comment
#3 (APA)
Results Pg 13. delete s
Although the statistical heterogeneity was fairly … #3 (APA)
Results p. 33 Heavy drinking days The phrasing naltrexone by CBI interaction sounds like
statistical … If the studies are consistent, of
high quality, direct, and clinically relevant, then the statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-270-bimp-disposition-comments.pdf
September 18, 2024 - We felt this granular approach would have very
low statistical power and also would be quite cumbersome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading-quiz.ppt
October 08, 2025 - Any of these four domains can be used when they are relevant and the appropriate data or statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/grading-quiz.ppt
October 08, 2025 - Any of these four domains can be used when they are relevant and the appropriate data or statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
March 01, 2013 - Statistical heterogeneity represents effect size variability between
studies. … Journal of the American
Statistical Association. 2006;101:447-59.
26. Lu G, Ades A. … Statistical
approaches for conducting network meta-
analysis in drug development. … Statistical Review for Sanctura XR
(Trospium Chloride) Extended Release
Capsules. 2007. … Statistical Review for Sanctura XR
(Trospium Chloride) Extended Release
Capsules. 2007.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - example, on page 39,
authors state that a study on anakinra was rated as poor because of
insufficient statistical … Statistical
methods used are appropriate.
Thank you. … Outcome measures appropriate as are statistical methods. … Otherwise, I thought that the data abstraction methods, quality
assessment, rating the body of evidence, statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-genetic_methods.pdf
July 01, 2012 - Finally, statistical issues must be taken into account when evaluating studies of genetic tests. … results are often derived from analytically complex studies that have
undergone a very large number of statistical … Principle 8: Understand statistical issues of particular relevance to genetic tests. … warfarin dose (e.g., age, BMI)
with the use of clinical factors alone.33–35
Principle 8: Understand statistical … are sometimes derived from analytically complex studies that have
undergone a very large number of statistical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - Based on their extensive and well
performed statistical analysis, the authors found limited
evidence … Stat Med 2000),
suboptimal statistical properties (as suggested in the
Cochrane Handbook of Systematic … Peer Reviewer #9 Methods I have some concerns about the statistical methods as outlined
below:
I … Definitions, outcome measures
and statistical methods are appropriate. … Peer Reviewer #10 Clarity and
Usability
This is a very detailed analysis containing statistical concepts
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-glucose-control_research.pdf
July 01, 2010 - To use these variables in the statistical models, we
collapsed the data into two-month intervals (i.e … We did not test for statistical differences across
groups as even small differences are statistically