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Showing results for "statistical".

1. Development and Implementation of Secure Statistical Analyses on Distributed Databases | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/dsitributed-database-analyses/abstract
   December 01, 2019 - Home Evidence Reports Development and Implementation of Secure Statistical … As a result, this current project is to develop, test, and validate a method for secure statistical analysis … The successful implementation of the secure statistical analysis within a distributed database model … Methods: This work is intended to enable remote execution of multivariate statistical analysis within … Project Timeline Development and Implementation of Secure Statistical Analyses on Distributed Databases

2. Quantitative Synthesis: Chapter 4. Quantifying, Testing, and Exploring Statistical Heterogeneity (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-4.pdf
   July 01, 2019 - Quantifying, Testing, and Exploring Statistical Heterogeneity Quantitative Synthesis Chapter 4. … Quantifying, Testing, and Exploring Statistical Heterogeneity Prepared for: The Agency for Healthcare … Learning objective Statistical heterogeneity • Statistical heterogeneity occurs when estimates across … heterogeneity tests statistical for statistical heterogeneity in meta-analysis is Q:11 ► Q is computed … Quantifying, Testing, and Exploring �Statistical Heterogeneity Learning objective Statistical heterogeneity

3. Statistical Design and Analytic Considerations for N-of-1 Trials (Chapter 4) | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-1
   August 01, 2019 - Introduction In this chapter, we discuss key statistical issues for n-of-1 trials—trials of one patient … As a consequence, it is usually worth constructing a proper statistical model that incorporates these … Local Knowledge and Statistical Methods The personalized nature of n-of-1 trials indicates that the … Automation of Statistical Modeling and Analysis Procedures The implementation of the statistical modeling … Statistical Design and Analytic Considerations for N-of-1 Trials.

4. Quantitative Synthesis Chapter 3. Choice of Statistical Model for Combining Studies (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
   February 01, 2018 - Choice of Statistical Model for Combining Studies Quantitative Synthesis Chapter 3. … The statistical basis of meta-analysis. Stat Methods Med Res. 1993;2(2):121-45. … Choice of Statistical Model for Combining Studies Slide Number 2 Statistical models for meta-analysis … Statistical models for meta-analysis� Recommendations for �Chapter 3. … Statistical models for meta-analysis� Author References

5. Underperformance of Contemporary Phase III Oncology Trials and Strategies for Improvement | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/grant-manuscripts/underperformance-abstract
   June 01, 2024 - Jun 5, 2024 Abstract | June 2021 Background: Statistical … Among 56 OS endpoints that achieved statistical significance, the true efficacy of experimental therapies … Among 131 OS endpoints that did not achieve statistical significance, the true efficacy of experimental … Conclusions: Current statistical approaches detect almost all truly effective oncologic therapies studied

6. Quantitative Synthesis: Chapter 1. Decision To Combine Trials (pdf file)
   effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-1.pdf
   July 01, 2019 - Performance of statistical methods for meta-analysis when true study effects are non-normally distributed … are not concerns. ► Chapter 4 covers statistical heterogeneity in detail • Statistical heterogeneity … http://www.training.cochrane.org/handbook Assessing statistical heterogeneity • I2: proportion of … Performance of statistical methods for meta-analysis when true study effects are non-normally distributed … heterogeneity Assessing statistical heterogeneity Pooling decision tree (1) Pooling decision tree

7. Development of Statistical Estimators to Address Questions of Comparative Effectiveness in Elderly Heart Failure Patients | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/heart-failure-seniors-estimators/research
   November 01, 2017 - FAQs Home Evidence Reports Development of Statistical … SHARE: Development of Statistical … or EBBBs compared with no BBs were statistically significant (P = .002 for both), but there was no statistical … Project Timeline Development of Statistical Estimators to Address Questions of Comparative Effectiveness … 2017 Internet Citation: Research Report: Development of Statistical

8. Conducting Quantitative Synthesis When Comparing Medical Interventions: AHRQ and the Effective Health Care Program | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/methods-guidance-quantitative-synthesis/methods
   December 01, 2019 - Statistical heterogeneity: variability in observed treatment effects across studies. … These decisions require clinical insights as well as statistical expertise. … A p-value of 0.10 instead of 0.05 could be used to determine statistical significance. … Statistical power analysis for the behavioral sciences. Hillsdale, NJ: L. … A comparison of statistical methods for meta-analysis. Stat Med 2001;20:825–840.

9. OpenMetaAnalyst: Powerful Open-Source Software for Meta-Analysis | Effective Health Care (EHC) Program
   effectivehealthcare-admin.ahrq.gov/products/open-meta-analyst/abstract
   August 01, 2019 - methods used in the meta-analysis of diagnostic tests, validate newly proposed methods, develop new statistical … meta-analyses, it is therefore imperative that they are performed correctly, i.e., that appropriate statistical … Unfortunately, the methods available in such software are usually dated; new methods are implemented in statistical

10. Information Technology Infrastructure for N-of-1 Trials (Chapter 5) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014
    August 01, 2019 - analysis and aggregation of raw individual patient-level data Statistical analysis and aggregation … Trial outcomes are monitored using Shewhart-style statistical control charts (Figure 5–2). … Statistical Analysis Modules Chapter 4 identifies a variety of options for performing statistical … the section “Automation of Statistical Modeling and Analysis Procedures” in Chapter 4). … For statistical procedures that are implemented in a statistical language such as R or Matlab, export

11. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
    October 01, 2010 - Statistical heterogeneity: variability in observed treatment effects across studies. … These decisions require clinical insights as well as statistical expertise. … A p-value of 0.10 instead of 0.05 could be used to determine statistical significance. … Statistical power analysis for the behavioral sciences. Hillsdale, NJ: L. … A comparison of statistical methods for meta-analysis. Stat Med 2001;20:825–840. 37.

12. Conducting Quantitative Synthesis when Comparing Medical Interventions: AHRQ and the Effective Health Care Program (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
    October 01, 2010 - Statistical heterogeneity: variability in observed treatment effects across studies. … These decisions require clinical insights as well as statistical expertise. … A p-value of 0.10 instead of 0.05 could be used to determine statistical significance. … Statistical power analysis for the behavioral sciences. Hillsdale, NJ: L. … A comparison of statistical methods for meta-analysis. Stat Med 2001;20:825–840. 37.

13. Expanded Guidance on Selected Quantitative Synthesis Topics | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/quantitative-synthesis-expanded-methods/methods
    December 01, 2019 - Statistical Efficiency in Clinical Trials Composite outcomes can improve statistical efficiency, increasing … Statistical and clinical homogeneity of the components should be verified. … Summary Composite outcomes typically increase statistical efficiency. … Statistical heterogeneity Statistical tests Specify how statistical heterogeneity is assessed and … Statistical power analysis for the behavioral sciences, 2nd ed.

14. Quantitative Synthesis: Learning Objectives and Recommendations (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-learning-objectives-recommendations.pdf
    July 01, 2019 - statistical heterogeneity in all meta-analyses … A comparison of statistical methods for meta‐analysis. Stat Med 2001;20(6):825-40. … The statistical basis of meta-analysis. Stat Methods Med Res. 1993;2(2):121-45. … Statistical models for meta-analysis� Recommendations for �Chapter 4. … Statistical heterogeneity Recommendations for �Chapter 5.

15. App-E-Opioid-Chronic-Pain-Surveillance-Report-2 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
    January 01, 2021 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other … Did the Study Perform Appropriate Statistical Analyses on Potential Confounders?

16. App-E-Opioid-Chronic-Pain-Surveill-Report-1 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveill-report-1.xlsx
    January 01, 2021 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other … Did the Study Perform Appropriate Statistical Analyses on Potential Confounders?

17. Methods Guide for Comparative Effectiveness Reviews - Expanded Guidance on Selected Quantitative Synthesis Topics (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - Statistical Efficiency in Clinical Trials Composite outcomes can improve statistical efficiency, increasing … Statistical and clinical homogeneity of the components should be verified. … Summary • Composite outcomes typically increase statistical efficiency. … Statistical heterogeneity Statistical tests Specify how statistical heterogeneity is assessed and … Statistical power analysis for the behavioral sciences, 2nd ed.

18. App-E-Opioid-Chronic-Pain-Surveillance-Report-3 (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-3.xlsx
    January 01, 2021 - Did the Study Perform Appropriate Statistical Analyses on Potential Confounders (i.e., Age, Sex, Other … Did the Study Perform Appropriate Statistical Analyses on Potential Confounders?

19. Suicide Prevention | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/suicide-prevention/research-protocol
    January 01, 2020 - What are potential sources of bias for these statistical methods? … Through valid and reliable statistical methods, these linked data can be analyzed for sources of bias … When available, we will also tabulate the actual statistical packages and procedures used. … References Statistical Abstracts of the United States. … To be more thorough in identifying statistical methods.

20. The Empirical Evidence of Bias in Trials Measuring Treatment Differences | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/treatment-effects-bias/research
    November 01, 2017 - provider blinding; detection bias through outcome assessor and data analyst blinding and appropriate statistical … studies on patient and/or provider blinding, 8 studies on assessor blinding, 2 studies on appropriate statistical … In contrast, evidence was generally inconsistent and imprecise in relation to confounding, adequate statistical … to measure biases, the thoroughness of reporting of trial conduct that was required, approaches to statistical