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21. Cholesterol Management Evidence and Resources | Agency for Healthcare Research and Quality
    www.ahrq.gov/evidencenow/projects/heart-health/evidence/cholesterol.html
    March 01, 2021 - Substantial evidence shows that taking a statin medication each day to manage blood cholesterol can reduce … People who have already had a heart attack or stroke have also been shown to benefit from statin use … Recommendation: The USPSTF recommended starting statin use for primary prevention of cardiovascular … The USPSTF recommended discussing statin use in similar patients with more moderate risk of a CVD event … All patients at high risk should receive a high- or moderate-intensity statin unless contraindicated

22. Evidence Summary: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/statin-use-in-adults-preventive-medication
    August 23, 2022 - Study Selection: Randomized clinical trials on statins vs placebo or no statin and statin intensity … Randomized clinical trials of statin therapy vs placebo or no statin, statin dosing strategies to target … statin dose. … Statin therapy, vs placebo or no statin, was not significantly associated with increased risk of study … therapy and higher- vs lower-intensity statin therapy; to more definitively determine whether statin

23. Final Research Plan: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/statin-use-in-adults-preventive-medication
    November 05, 2020 - to WhatsApp Share to Email Print Final Research Plan Statin … Do the benefits of statin treatment vary in subgroups defined by demographic, clinical, or socioeconomic … What are the harms of statin treatment?     b. … Do the harms of statin treatment vary in subgroups defined by demographic, clinical, or socioeconomic … How do the benefits and harms of statin treatment vary according to its intensity?

24. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_executive.pdf
    September 01, 2009 - Evidence comparing various doses of statin- ezetimibe, statin-fibrate, statin-niacin, and statin-BAS … , statin-BAS, and statin- omega-3 combinations. … , statin-BAS, and statin-omega-3 combinations. … the statin-fibrate, statin-niacin, statin-BAS, and statin-omega-3 combinations with respect to statin … statin-niacin, and statin-omega-3 combinations.

25. Archived: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - statin use in adults aged 40 to 75 years are small. … There are limited data on different statin dosing strategies; trials that directly compare titrated statin … Harms of Statin Use In randomized trials of statin use for the primary prevention of CVD, statin therapy … adults 76 years and older who are not already taking a statin. … to "which population should be prescribed statin therapy?"

26. Disposition of Comments Report for CER 132 Combination Therapy Versus Intensification of Statin Monotherapy: An Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_disposition-comments.pdf
    September 01, 2014 - We agree that new trials with statin mono vs. statin + “add on” combo agent (e.g., ACCORD, AIM HIGH) … Statin/niacin vs statin/EZE: fewer adverse cardiac events with statin/niacin v statin/EZE (Taylor 2009 … statin combo therapies. … lower incidence of major cardiovascular events with statin+niacin than with statin+ezetimibe. … as a potent statin alone.

27. Reducing Disparities in the Primary Prevention of Cardiovascular Disease (pdf file)
    www.ahrq.gov/sites/default/files/wysiwyg/professionals/prevention-chronic-care/decision/research-centers/persell_cvd_disparities.pdf
    June 02, 2025 - Statin drugs decrease CVD illness and mortality in people at high risk. … in statin use among people of different race, ethnicity, and socioeconomic status. … Will patients who receive outreach from care managers seek out and obtain statin treatment to lower …  Barriers to at risk patients starting a statin regiment include: – Primary care clinicians focus … , as was done in this study) may more effectively increase appropriate statin use and lower CVD risk

28. Archived: Evidence Summary: Statins for Prevention of Cardiovascular Disease in Adults: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Preventive Medication | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-statins/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - We included randomized trials of statin therapy vs placebo or no statin and assessed all-cause mortality … Benefits of Statin Treatment Key Question 1a. … What are the harms of statin treatment? … How do benefits and harms vary according to statin treatment potency? … statin therapy is associated with increased diabetes or cataract risk; and to determine how statin intensity

29. S143 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
    October 01, 2007 - We identified statin initiators and those eligible for statin initiation (based on having a physician … RESULTS There was an average of 504 (�60.0) statin initiators and 8090 (�1168) statin noninitiators … Statin Initiators and Randomly* Selected Comparators No. … Statin Initiators and Matched Comparators (Reduced Model) No. … Statin Initiators and Comparators (Expanded Model) No.

30. High-Cholestorol-Medicines-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medicines-update_executive.pdf
    February 01, 2014 - doses of statin could be used. … monotherapy, which enabled us to synthesize data across statin type and statin dose. … Included studies of fibrates + statin. Included studies of niacin + statin. … statin potency. … therapy with omega-3 fatty acid and statin to intensification of statin monotherapy.

31. STATISTICAL BRIEF #458: Out-of-Pocket Health Care Expenses for Non-Elderly Families by Income and Family Structure, 2015
    meps.ahrq.gov/data_files/publications/st458/stat458.shtml
    November 01, 2014 - medications, and each specific class of statin medication during the year. … Trends in Statin Therapy among Adults (Age ≥ 18), United States, 2000 to 2011 . … 17.6 23.5 30.6 34.0 38.3 40.8 Generic Statin 0.1 1.1 2.4 11.6 20.5 26.5 Branded Statin 17.5 … Number of statin fills among adults (age ≥ 18), 2000–2001 to 2010–2011 Type of Statin 2000–2001 ( … 652 762 741 674 610 529 Generic Statin NA 334 425 401 278 157 Branded Statin 653 774 756

32. Articulate Word Output (pdf file)
    www.ahrq.gov/sites/default/files/wysiwyg/evidencenow/heart-health/primary-prevention-cvd-with-statins.pdf
    June 02, 2025 - And, finally, to examine effective techniques for encouraging adherence to statin therapy. 4 Mr … Would you recommend a statin for CVD risk reduction in this patient? How would you decide? … As such, we recommend that you initiate a moderate dose generic statin for primary prevention. … It assumes a relative risk reduction of 25% with statin therapy. … their statin medication within six months.

33. Strategies to Better Manage Lipids—Statin Pearls | Agency for Healthcare Research and Quality
    www.ahrq.gov/evidencenow/heart-health/cholesterol/statins.html
    September 01, 2018 - Strategies to Better Manage Lipids—Statin Pearls Resource title: Strategies to Better Manage … Lipids—Statin Pearls Resource description: This slide deck and transcript of a 20-minute video with

34. Clinic Intervention Tracking Sheet (doc file)
    www.ahrq.gov/sites/default/files/wysiwyg/evidencenow/tools-and-materials/skills-qi-tracking.docx
    June 02, 2025 - alert staff for lipid panel in general population for low risk patients CDS reminder to order statin … in ASCVD, IVD, CVD CDS reminder to order statin in DM CDS reminder to order statin in patients … with low-density lipoprotein (LDL) >=190 CDS reminder to order statin in general population with … Outreach list for DM not on statin Outreach list for LDL>=190 not on a statin Outreach … list for increased CVD risk not on statin Outreach list for smokers Agreement with community

35. Implementation Guide: Statin Use for the Primary Prevention of CVD in Adults: Patient-Facing CDS Intervention (pdf file)
    cds.ahrq.gov/sites/default/files/cds/artifact/1056/2024_CDS_Connect_IG_Statin_CVD_Patient_Facing_2.pdf
    January 01, 2024 - Those currently receiving or prescribed a statin medication. … These “Statin Use” artifacts exhibit two main differences. … The Statin Use: Patient-Facing artifact leveraged this previous work. a. … Statin Use for the Primary Prevention of Cardiovascular Disease in Adults. … Statin-induced rhabdomyolysis: a comprehensive review of case reports.

36. Psn-Pdf (pdf file)
    psnet.ahrq.gov/node/46911/psn-pdf
    May 02, 2018 - Errors in electronic health record–based data query of statin prescriptions in patients with coronary … Errors in Electronic Health Record-Based Data Query of Statin Prescriptions in Patients With Coronary … https://psnet.ahrq.gov/issue/errors-electronic-health-record-based-data-query-statin-prescriptions-patients … The authors evaluated how their institution's EHR measured a common quality metric—statin prescription … https://psnet.ahrq.gov/issue/errors-electronic-health-record-based-data-query-statin-prescriptions-patients-coronary

37. Implementation Guide: Statin Use for the Primary Prevention of CVD in Adults: Clinician-Facing CDS Intervention (pdf file)
    cds.ahrq.gov/sites/default/files/cds/artifact/18/2024_CDS_Connect_IG_Statin_CVD_Clinician_Facing.pdf
    January 01, 2024 - Alpha begin taking a statin. … • Those currently receiving or prescribed a statin medication. … Suggested order for a statin medication. 5. … These “Statin Use” artifacts exhibit two main differences. … Exclusions “statin medication order, …statement, … dispensed… within the past 2 years” A statin

38. Intervention Tracking (pdf file)
    www.ahrq.gov/sites/default/files/wysiwyg/evidencenow/results/research/intervention-tracking-worksheet-mw.pdf
    May 19, 2016 - mellitus Alert for a lipid panel in general population (low risk patients) Reminder to order a statin … in ASCVD (or IVD, or CVD) Reminder to order statin in diabetic patients Alert to order a statin … in pts with LDL ≥190 Alert to order statin in general population with increased risk (based on a … patients with uncontrolled hypertension Outreach to patients who need cholesterol measurement or statin … Outreach to tobacco users or smokers Outreach to patients with increased CVD risk who are not on a statin

39. Cholesterol Management in Primary Care (pdf file)
    www.ahrq.gov/sites/default/files/wysiwyg/evidencenow/heart-health/cholesterol-academic-detailing-guide.pdf
    July 07, 2015 - Statin benefits for patients with coronary artery disease1,2 i16% Reduction in absolute risk of … statin Diabetes LDL-C 70-189mg/dl, Age 40-75 y > 7.5% - Estimated 10-y ASCVD risk < 7.5% … Effectiveness of statin therapy in adults with coronary heart disease. Arch Intern Med. … The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease … Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes.

40. Implementation Guide: Statin Use for the Primary Prevention of CVD in Adults: Patient-Facing CDS Intervention (pdf file)
    cds.ahrq.gov/sites/default/files/cds/artifact/1056/2023_CDS_Connect_IG_Statin_CVD_Patient_Facing.pdf
    January 01, 2023 - • Those currently receiving or prescribed a statin medication. … There are two differences between the two “Statin Use” artifacts. … The Statin Use: Patient-Facing artifact leveraged this previous work. a. … Exclusions “statin medication order, … statement, … dispensed … within the past 2 years” A statin … Statin-induced rhabdomyolysis: a comprehensive review of case reports.