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421. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_june_2012.pdf
     January 01, 2012 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … Sequenom states that circulating fetal DNA can be obtained from a maternal blood sample very early … In May 2012, the company announced the prenatal test’s commercial launch in the United States and … Sequenom states that circulating fetal DNA can be obtained from a maternal blood sample very early

422. 15 Crosscutting Potential High Impact 2012-12-11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/15_crosscutting_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … Several versions of this model are being implemented in the United States, and we describe one of those … but several other community paramedicine models have been implemented recently across the United States … One clinical expert states, “This innovation may have the [p]otential to drive a wedge in the important

423. Gastric-Cancers-Supplementary-App-I (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-i.xlsx
     January 01, 2019 - ICEMAN - Primary studies RefID Study name State a single candidate effect modifier Was the effect modifier measured before or at randomization/assignment? State a single outcome and time-point of interest State a single effect measure 1: Was the direction of the effect modification correctly hypothesized a priori? 1: …

424. Disposition of Comments Report for Evidence Report/Technology Assessment No. 214 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
     February 25, 2014 - Reviewer 12 Introduction Key Question 2 states that the report will examine child outcomes, but there … excluded because it did not have validated cessation, but this paper (including the abstract) clearly states

425. Functional-Limitations-Horizon-Scan-High-Impact-1306 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/functional-limitations-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … The average wholesale cost of this drug in the United States is about $8,400 per 30-mg dose (one dose … Two phase III trials with 652 patients at 90 centers in Europe and the United States were reported … The manufacturer states that transfer to and from a patient’s wheelchair and the powered exoskeleton

426. MEDLINE Searches (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
     March 01, 2009 - Berg AO, United States Preventive Services Task Force. … United States. 60 or 120 mg/day; 1 year. … United States. 60 or 120 mg/day; 1 year. … United States and Europe. 2.5 mg/ day; 36 months. … United States. 1.25 or 2.5 mg/day; 3 months.

427. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/infectious-disease-horizon-scan-high-impact-1512.pdf
     January 28, 2016 - or for which some preliminary efficacy data in the target population are available) in the United States … That limited efficacy coupled with low incidence of dengue virus infection in the United States limit … HCV has six genotypes, with genotype 1 accounting for about 70% of HCV infections in the United States … Of the 1 million people with HIV infection in the United States, about 50,000 also have chronic HCV … However, its 2015 Preferred Drug Exclusions List states that Sovaldi may be covered in patients who

428. Interventions-Horizon-Scan-High-Impact-1306 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/interventions-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … Several versions of this model are being implemented in the United States, and we describe one of those … but several other community paramedicine models have been implemented recently across the United States … One clinical expert states, “This innovation may have the [p]otential to drive a wedge in the important

429. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/12_pregnancy_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … The first official human milk bank in the United States was established in 1919. 10 The Human Milk

430. Disposition of Comment Report for Wireless Motility Capsule Versus Other Diagnostic Technologies for Evaluating Gastroparesis and Constipation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/wireless-motility-capsule_disposition-comments.pdf
     May 20, 2013 - of times and the worst of times: sustaining the future of academic gastroenterology in the United States … The paper states, "anorectal outlet function testing was not avoided by WMC performance (0%)." … The draft report states adding WMC to GES improves sensitivity and reports GES sensitivity ranges from … use of laxatives seems to be a European recommendation and is infrequently performed in the United States … The Use of Colonic Testing to Guide Treatment in the Introduction chapter now states, “If testing confirms

431. Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
     September 26, 2014 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … Furthermore, about 86 million people in the United States have prediabetes or are at risk of developing … The Mayo Foundation for Medical Education and Research (MFMER) states that T1DM risk factors include … MFMER states that all patients with T1DM require insulin therapy.

432. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
     September 01, 2011 - Summary This might also be a good place to mention that investigations should also report disease states … ACR Pediatric 75 at month 12) are not included, even though the methods section of the draft report states

433. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
     June 01, 2010 - We have revised our language and states, in both the Executive Summary and main report, that the analysis … Introduction Page 7, line 44: "lack of approval outside the United States" would imply that rFVIIa has … been approved for trauma, intracranial hemorrhage, cardiac surgery etc. in the United States. … Tranexamic acid is not marketed in the United States. … The report no longer states that rFVIIa is common.

434. Dietary-Supplements Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
     January 01, 2013 - CER #51: Dietary Supplements in Adults Taking Cardiovascular Drugs Original release date: April, 2012 Surveillance Report: April, 2013 Key Findings: - A small number of new studies were identified on the interaction between omega-3 fatty acids, both over-the- counter and prescription-grade, on the ef…

435. Comparative Effectiveness Research Review Disposition of Comments Report (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disabilities-quality-improvement-outcomes_disposition-comments.pdf
     October 15, 2012 - A detailed discussion of The National Core Indicators, as the report states, is beyond the scope of … The NCI represents a significant effort to create a core set of indicators states can use to monitor … All I can say if that these results prompted me to think about ways of helping states moving to managed … Peer Reviewer #3 Discussion The conclusion also states “The broad scope of the review was, however

436. PULMONARY with "Discussions" in Exec Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
     June 01, 2013 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States …  Key Facts: COPD is the third most common cause of death and chronic complications in the United States … pulmonary disease (COPD) is the third most common cause of death and chronic complications in the United States

437. Disposition of Comments for Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
     August 27, 2012 - Commentator & Affiliation Section Comment Response Peer reviewer #6 General The introduction states … Introduction provides a succinct overview of ASD in adolescence and young adulthood, and it clearly states … The report states that it is a number to allow for sufficient effect size, but is that a statistical … The review states, “The upper age of 30 accounted for potential developmental delays in individuals”

438. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
     August 24, 2011 - Centers for Disease Control and Prevention (CDC), more than 4 million births occur in the United States … Source: www.effectivehealthcare.ahrq.gov Published Online: August 24, 2011 3 the United States … Labor pain management in the United States: understanding patterns and the issue of choice.

439. Disposition of Comments Report for Acute Migraine Treatment in Emergency Settings (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
     November 27, 2012 - Peer Reviewer #7 Methods Table 2 states one of the outcomes is a 10-point verbal scale. … I personally have practiced in approximately 20 EDs in 4 different states and never once have given

440. Disposition of Comments for Screening of Methicillin-Resistant Staphylococcus Aureus (MRSA) (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mrsa-screening-2010_disposition-comments.pdf
     January 01, 2010 - One of the strengths of this report is that it clearly and explicitly states the target populations … It is noteworthy that the report states that the effectiveness of hand hygiene in preventing the spread … ) Intro/ES Introduction: Executive summary: ES-2, line 17 and page 3, line 19-20: The manuscript states … The Methods chapter states, “The quality of the abstracted studies and the body of evidence was assessed … At the bottom of the page, the report states that health care-associated MRSA acquisition is an indirect