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361. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … a physical therapy protocol, as well as diet and hormone counseling as needed.6 The manufacturer states … that the new Regenexx procedure offered in the United States is compliant with Code of Federal Regulations … individual during the same surgical procedure.19,20 At least 22 medical facilities in the United States

362. Disposition of Comments Report for Multigene Panels in Prostate Cancer Risk Assessment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_disposition-comments.pdf
     July 03, 2012 - In 1b it states “the incremental gain in AUC observed when the predictive model including the SNP data

363. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … ’s PriceGuide Database, the average price paid for the ReShape intragastric balloon in the United States … Available: http://pro.reshapeready.com/now-fda-approved- in-the-united-states/. 20. … Novo Nordisk to promote drug to treat obesity in United States. [internet].

364. Behavioral Programs for Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
     September 11, 2015 - private-sector organizations in their efforts to improve the quality of health care in the United States … Over the past few decades, much of the care and education of people with diabetes in the United States … For both T1DM and T2DM, we included studies conducted in the United States or other highly developed … Our findings are generally applicable to these settings in the United States. … The results seem to be applicable to community health settings in the United States.

365. EHC Protocol: Addressing Social Isolation To Improve Health of Older Adults: A Rapid Evidence Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-surgical-report-cards.pdf
     July 01, 2023 - 2011 when 5 the search was done for the MHS II report in English and performed in the United States … Published in 2010 or earlier Setting Inpatient and outpatient surgical care settings in the United States … identify a recent eligible systematic review, the reviewer will use the criteria developed by the United States

366. Disposition of Comments_Comparative Effectiveness Review No. 261_Postpartum Care up to 1 Year After Pregnancy: A Systematic Review and Meta-analysis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/postpartum-care-one-year-disposition-comments.pdf
     June 02, 2023 - study screening (title/abstract and full text) was conducted and why KQ 1 was focused on the United States … and Canada and why KQ 2 was focused on the United States only. … The next sentence states the modification that was made for this systematic review: “Specifically,

367. 08 Functional Limitations Potential High Impact 2012-12-10 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/08_functional_limitations_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … Discussion The AHRQ priority area of functional limitations encompasses a wide range of disease states … In September 2011, Oceana Therapeutics launched Nasha/Dx in the United States. … The average wholesale cost of this drug in the United States is about $8,400 per dose.

368. Single-arm studies in comparative effectiveness reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
     January 01, 2013 - private-sector organizations in their efforts to improve the quality of health care in the United States … detailed clinical data on all patients receiving implantable ventricular assist pumps in the United States … Secular trends in diabetes-related preventable hospitalizations in the United States, 1998-2006.

369. Disposition of Comments Report for Local Hepatic Therapies for Metastases to the Liver From Unresectable Colorectal Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
     December 11, 2012 - As the reviewer states there were no comparative studies, and in the absence of such studies conclusions … page 54, Table 6 states median/range of age not reported -- it was as mean and range We apologize … Peer Reviewer #5 Results page 60, table 8 states TTP and TTLP not reported, both are reported Based … As our conclusion states we believe the most important outcomes to be overall survival, QOL and adverse

370. AHRQ’s Evidence-based Practice Center Program- Synthesizing evidence to improve health care practice and delivery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/epc-evidence-reviews-federal-agencies.pdf
     July 01, 2020 - programs, the Evidence-based Practice Center (EPC) Program, funds 9 independent EPCs across the United States

371. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
     March 10, 2010 - Revised: The United States Food and Drug Administration defines SAE as any untoward medical occurrence … In both the CPK and rhabdomyolysis sections, a sentence describing the Stein study (reference 104) states … We find this surprising, because the publication states that "Efficacy analyses were based on a modified … If this description is insufficient, the study protocol (on file with the FDA) states "For the efficacy … that the study was described in the publication as "double-blind" and Jadad et al., 1996 explicitly states

372. Slide 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
     August 27, 2012 - Slide 1 Research Triangle Institute RTI International is a trade name of Research Triangle Institute. www.rti.org The Use of Conjoint Analysis to Elicit Patient Preferences in Selecting Treatment Endpoints F. Reed Johnson, PhD Distinguished Fellow and Principal Economist Research Triangle Institute I…

373. CER 218 Disposition of Comments: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
     April 23, 2019 - George Jarekso- Amgen) Page 24 (Key Points on Key Question1) Comment: Page 24 of the Draft Report states … This is consistent w ith the Agency discussion on page ES-13 w hich states “w e found no usable data … George Jarekso- Amgen) Page 76 (Key Points on Key Questions 7 and 8) Comment: The Draft Report states … The revised Discussion section on future research needs states: “Future…studies should specify analysis … Document states “may” increase the risk.

374. Disposition of Comments Report for Biologic and Nonbiologic Systemic Agents and Phottherapy for Treatment of Chronic Plaque Psoriasis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_disposition-comments.pdf
     November 27, 2012 - Commentator & Affiliation Section Comment Response Introduction The background section on page 2 states … Executive Summary In the executive summary, page ES-12 it states that, “For the comparison of adalimumab … On page 31 of the report it states that five patients in a trial by Barker et al experienced infusion-related … reactions in the infliximab group whereas in Appendix F Table 11, it states that 17/649 patients experienced … 2012 17 Commentator & Affiliation Section Comment Response On page 31 of the report, it states

375. S96 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s96.pdf
     October 01, 2007 - operates in 63 hospital EDs, selected as a stratified probability sample of all hospitals in the United States … Washington, DC: United States General Accounting Office; 2000. 3. … Health, United States, 2005. In: Chartbook on Trends in the Health of Americans. … electronic injury surveillance system-cooperative adverse drug event surveillance project—six sites, United States … Spontaneous reporting in the United States. In: Strom B, ed. Pharmacoepidemiology. 4th ed.

376. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/dementia-horizon-scan-high-impact-1406.pdf
     February 01, 2015 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … According to the Alzheimer’s Association, over 5 million people in the United States were living with … National Center for Health Statistics places AD as the sixth-leading cause of death in the United States … Alzheimer disease in the United States (2010- 2050) estimated using the 2010 census.

377. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
     February 10, 2010 - utilization, decreased quality of life, and significant activity limitations.2,3 In the United States … In the United States, the annual cost (both direct and indirect) of asthma is estimated to be over $20 … Study geography Developed countries with a Human Development Index > 0.90 including: United States … The burden of asthma in the United States: level and distribution are dependent on interpretation of … Table 2-1 Lifetime Asthma Prevalence Percents by Age, United States.

378. CARDIOVASCULAR (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
     December 01, 2014 - developed for technologies and programs that appear to be close to diffusion into practice in the United States … or for which some preliminary efficacy data in the target population are available) in the United States … ES-5 Costs associated with the Watchman device have not been established in the United States. … The estimated cost of HF in the United States in 2013 was $32 billion. … (Natick, MA) in 2011.16 The device is limited to investigational use in the United States.15 Atritech

379. Disposition of Comments Report for Interventions for Adult Offenders With Serious Mental Illness (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-adults-prisons_disposition-comments.pdf
     August 21, 2013 - The report states between line 14 and 19 of this section that “ The R & R cognitive skills program … Table A states the consistency is unknown. This is incorrect. … While this is not the most common arrangement, there are some other states with the same model, e.g … has been determined by case law, 2. if the facility voluntarily seeks accreditation, or 3. in some states … The studies were conducted in the United States, Canada, United Kingdom, New Zealand and Australia.

380. Disposition of Comments Report for Comparison of Characteristics of Nursing Homes and Other Residential Long-Term Care Settings for People With Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_disposition-comments.pdf
     October 23, 2012 - It states it is only examined in context of the other KQs but appears forgotten in the ES We have