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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard
Meta-analysis … Background
When evaluating medical test performance, a reference standard for comparison is considered … Gold Standard: A reference standard that is considered adequate in defining the presence or absence of … standards, study designs, et cetera, between the studies
Challenges
Trikalinos TA, Coleman CI, Griffith … standards, study designs, or others.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard
Meta-analysis … Background
When evaluating medical test performance, a reference standard for comparison is considered … Gold Standard: A reference standard that is considered adequate in defining the presence or absence of … standards, study designs, et cetera, between the studies
Challenges
Trikalinos TA, Coleman CI, Griffith … standards, study designs, or others.
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effectivehealthcare.ahrq.gov/products/iom-standards
April 10, 2013 - EPC Response to IOM Standards for Systematic Reviews
Timeline
April 09, 2013
Topic … Initiated
April 10, 2013
White Paper
EPC Response to IOM Standards
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effectivehealthcare.ahrq.gov/products/iom-standards/white-paper
April 10, 2013 - EPC Response to IOM Standards for Systematic Reviews
White Paper April 10, 2013 Web Version [NLM Site … Following the release of these standards in March 2011, the EPC program established a collaborative process … to comparatively examine the standards with respect to general EPC practice and guidance. … Purpose
The purpose of this process was to assess which elements of the IOM standards should be adopted … Results
EPC directors identified 34 elements across the 21 standards that required remediation and
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
January 01, 2011 - Reference Standards for the Diagnosis of Iron
Deficiency
A total of 27 studies were included for Key … However, there were large variations
across studies in the definitions of these reference
standards … However, there existed a large heterogeneity in the
reference standards used in these studies as well … However, because
the reference standards (Hb versus Hct/decrease in
EPO dose) were not comparable, … However,
across studies, the definitions of these reference standards vary widely.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/iom-standards_white-paper.pdf
April 01, 2013 - into four chapters:
• Standards for Initiating an SR (consisting of 8 standards with 28 elements) … • Standards for Finding and Assessing Individual Studies (consisting of 6 standards with 30
elements … )
• Standards for Synthesizing the Body of Evidence (consisting of 4 standards with 13
elements) … • Standards for Reporting an SR (consisting of 3 standards with 11 elements)
The following methods were … While this guidance is generally consistent with IOM standards, certain elements of the IOM
standards
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - standard and
ranged from 0.72 to 0.75 in studies that used other reference standards. … standard and
ranged from 0.65 to 0.86 in studies that used other reference standards. … standard or mixed reference standard; only 3 studies evaluated an
imaging/clinical reference standard … HCC because few studies evaluated alternative reference standards. … Evaluating
diagnostic accuracy in the face of multiple reference standards.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/registry-of-patient-registries_research_1.pdf
April 15, 2019 - Standardization
across outcome measures is a critical starting point. … No publications on harmonization or
standardization of data elements for registries were identified, … In contrast to much of the clinical research activity, EHR
data standardization efforts are largely … Standardization of Questions in Rare Disease
Registries: The PRISM Library Project. … Standardization of terminology, definitions and
outcome criteria in immune thrombocytopenic
purpura
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/registry-of-patient-registries_research.pdf
April 15, 2019 - Standardization
across outcome measures is a critical starting point. … No publications on harmonization or
standardization of data elements for registries were identified, … In contrast to much of the clinical research activity, EHR
data standardization efforts are largely … Standardization of Questions in Rare Disease
Registries: The PRISM Library Project. … Standardization of terminology, definitions and
outcome criteria in immune thrombocytopenic
purpura
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effectivehealthcare.ahrq.gov/products/health-systems/quality-improvement
August 08, 2018 - definitions of QI interventions from the literature, and selected two definitions from AHRQ 1 and Standards … A consolidated SoF table will be derived from relevant reporting elements of Standards for Quality Improvement … Reporting Excellence (SQUIRE 2.0); 2 Standards for Reporting Implementation Studies (StaRI); 3 Template … Standards for Quality Improvement Reporting Excellence 2.0: revised publication guidelines from a detailed … Standards for Reporting Implementation Studies (StaRI): explanation and elaboration document.
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-rev-team-confidentiality-form.pdf
September 01, 2018 - The IOM report on Standards for Systematic Review2 also emphasizes the importance of protecting
systematic … Finding What Works in Health Care: Standards for Systematic
Reviews. … /Standards%20for%20Systematic%20Review%202010%20Insert.
pdf. … Finding What Works in Health Care: Standards for Systematic Reviews. … /Standards%20for%20Systematic%20Review%202010%20Insert.pdf.
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-ki-tep-confidentiality-form.pdf
August 01, 2020 - Consistent with the IOM recommendations on Standards for Systematic Reviews (1) to protect
the independence … Finding What Works in Health Care: Standards for Systematic Reviews. … /Standards%20for%20Systematic%20Review%202010%20Insert.pdf. … Finding What Works in Health Care: Standards for Systematic Reviews. … /Standards%20for%20Systematic%20Review%202010%20Insert.pdf.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
July 24, 2013 - In addition, the use of different reference standards—such as those for explanted liver
specimens in … Therefore,
potential variation in test performance with different reference standards also should be … standard, apply the reference standard to all patients, use blinded interpretation of the diagnostic … standard (nonpathologically based reference standard)
Table 1. … standard will be
considered in the context of the reference standard used.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-app-protocol.pdf
January 01, 2018 - The first step is to delineate the
characteristics and minimum standards to inform the development of … What characteristics and minimal standards of available behavioral health mobile
applications need … The IAB develops industry standards to
support standardization in the digital advertising industry and … Evidence standards framework for
digital health technologies. https://www.nice.org.uk/about/what-we-do … /our-
programmes/evidence-standards-framework-for-digital-health-technologies.
13.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-app-protocol-updated.pdf
January 01, 2018 - The
first step is to delineate the characteristics and minimum standards to inform the
development … What characteristics and minimal standards of available behavioral health mobile
applications need … The IAB develops industry standards to
support standardization in the digital advertising industry and … Evidence standards framework for
digital health technologies. https://www.nice.org.uk/about/what-we-do … /our-
programmes/evidence-standards-framework-for-digital-health-technologies.
13.
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effectivehealthcare.ahrq.gov/system/files/docs/topic-brief-endotracheal-intubation.pdf
January 26, 2021 - They are requesting the development of standards for endotracheal
intubation to promote practice change … Decision:
The EPC program synthesizes and appraises existing evidence and does not develop clinical
standards … However, as of 2011, that rate had decreased to 0.4 per 100,000 due to
improved safety standards and … stenosis is estimated at 4.9 per million in
adults.9
The nominator asks for development of clinical standards … Resources
While the proposed action, the development of clinical guidance or standards, falls outside
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-performance_methods.pdf
July 01, 2012 - Of the many challenges that pertain to issues with reference standards, we will
discuss only one, namely … Imperfect Reference Standards
What is meant by “imperfect reference standard,” and why is it
important … Diagnostic Accuracy, or the Case of the “Perfect” Reference Standard
A “perfect” reference standard … Identifying (Defining) the Reference Standard
One consideration is what reference standard is most … Meta-
analysis of diagnostic tests with imperfect
reference standards.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
January 01, 2013 - What reference standards
are used for the diagnosis of iron
status in studies evaluating test
accuracy … These variations in
the reference standards in the published studies resulted in incomparable study … However, across studies, there are
large variations in the definitions of these reference standards. … However, across studies, there are large
variations in the definitions of these reference standards. … standards used in many existing studies, and often referred
as the reference standard for functional
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - An “imperfect reference standard” is a reference standard test that misclassifies “true” status at a … lead to reference standard bias. … Reference Standard Validity
Most reference standards are not perfect, and we accept this. … Meta-analysis of diagnostic tests with imperfect reference standards. … Meta-analysis of diagnostic tests with imperfect reference standards.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-options-summarizing.ppt
June 01, 2012 - An “imperfect reference standard” is a reference standard test that misclassifies “true” status at a … lead to reference standard bias. … Reference Standard Validity
Most reference standards are not perfect, and we accept this. … Meta-analysis of diagnostic tests with imperfect reference standards. … Meta-analysis of diagnostic tests with imperfect reference standards.