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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
June 01, 2023 - subject matter expert panel which will
assess the feasibility of developing consensus-based quality standards … standard or
method to detect the impact of
screening
KQ2: No reference standard to
determine the … • Reference standard: The domain will evaluate whether the reference standard, its
conduct, or its … interpretation may have introduced bias, taking into account the
quality of the reference standard … The assessment will take into account whether the interval
between the tool and the reference standard
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effectivehealthcare-admin.ahrq.gov/sites/default/files/lung-cancer-staging_executive.pdf
April 01, 2016 - For comparative accuracy (KQ1), the study must have
compared both tests to a common reference standard … The reference standard must not have been defined
by either imaging test being assessed. … We set no
requirements on what the reference standard must be
(e.g., biopsy, clinical followup). … standard was used), risk of bias items, and
outcome data. … standard.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colorectal-cancer-staging_research-protocol.pdf
May 20, 2013 - Reference Standards To Assess Test Performance
o Histopathological examination of tissue
o Intraoperative … Were readers of the diagnostic test of interest blinded to the results of the reference standard? … Were readers of the reference standard blinded to all other clinical information?
10. … Were patients assessed by a reference standard regardless of the test’s results?
11. … Were all patients assessed by the same reference standard regardless of the test’s results?
12.
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effectivehealthcare-admin.ahrq.gov/products/library-depression/white-paper
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
August 09, 2013 - Instead, the imperfect reference standard is clinical followup. … The study must have compared both
tests to a reference standard.
3. … Is the reference standard likely to correctly classify the target condition?
7. … who underwent different reference standards such as clinical follow-up and surgical
findings)? … Were readers of both tests of interest blinded to the results of the reference standard (or the
reference
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effectivehealthcare-admin.ahrq.gov/products/breast-biopsy-update/research-protocol
December 01, 2019 - Comparators (reference standard and comparator index tests)
For test performance outcomes (KQ 1) the … findings according to core-needle biopsy that are classified as positive by the reference standard) … are found to be invasive according to the reference standard)
For KQ 2:
Rate of inconclusive … The reference standard is used in their definition and is not a “comparator test.” … Studies must have used as reference standard for core-needle biopsy one or more of the following: open
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effectivehealthcare-admin.ahrq.gov/products/safety-emerging-methods/overview
November 01, 2017 - Designed Delays Versus Rigorous Pragmatic Trials: Lower Carat Gold Standards Can Produce Relevant Drug … Designed Delays vs Rigorous Pragmatic Trials: Lower Carat Gold Standards Can Produce Relevant Drug Evaluations
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effectivehealthcare-admin.ahrq.gov/products/lumbar-spondylolisthesis/white-paper
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
March 14, 2012 - Previous consensus
recommendations from 2008 established baseline standards for scintigraphy and discussed … standard tests like scintigraphy. … Radiopaque Markers
Slow-transit constipation is defined by the reference standard of radiopaque marker … Gastroparesis: The reference standard is a 4-hour gastric emptying study.
2. … standard is a 4-hour gastric emptying study
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-249-malnutrition-hospitalized-adults-evidence-summary_0.pdf
October 01, 2021 - malnutrition
while other patients were either (1) not screened or assessed or (2) assessed with a
reference … standard (i.e., imaging or SGA).
-
effectivehealthcare-admin.ahrq.gov/products/ptsd-pharm-non-pharm-treatment-update/research
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effectivehealthcare-admin.ahrq.gov/products/renal-cancer/research-protocol
December 01, 2019 - Risk: Low/High/Unclear
Domain 3: Reference Standard
Is the reference standard likely to correctly … (Yes/No/Unclear)
Were the reference standard results interpreted without knowledge of the results … (Yes/No/Unclear)
Could the reference standard, its conduct, or its interpretation have introduced … (Yes/No/Unclear)
Did all patients receive a reference standard? … (Yes/No/Unclear)
Did all patients receive the same reference standard?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
December 08, 2014 - The reference standard must not have been defined
by either imaging test being assessed. … We will set no requirements on what the
reference standard must be (e.g., biopsy, clinical follow-up … who underwent different reference standards such as clinical
follow-up and surgical findings)? … Were readers of both tests of interest blinded to the results of the reference standard
(or the reference … Were the people determining the reference standard unaware of the diagnostic test
results?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/white-paper-standardized-library.pdf
February 01, 2019 - updating of outcome measures would appear vital to the ultimate success of any harmonization
and standardization … This lack of standardization
introduces the potential for different providers to use different definitions … Additionally, several
consensus-based efforts aimed at harmonization and standardization exist, providing … http://www.hl7.org/implement/standards/product_brief.cfm? … curation and updating of
outcome measures is vital to the ultimate success of any harmonization and standardization
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
November 19, 2009 - fundamental shortcomings in the design, conduct, and reporting of diagnostic accuracy
studies.34 The STAndards … Errors
made by the reference standard bias the usual estimators of sensitivity and specificity of
the … standard) can be jointly false negative for cancers with little
intraluminal manifestation or jointly … Treating colonoscopy as an error-free reference standard likely overestimates the ability
of the camera … Meta-
analysis of diagnostic tests with
imperfect reference standards.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
January 01, 2009 - The results of the test under evaluation are compared to those from a reference standard
in order to … standard or when the
new test is thought to be better than the current reference standard. … Strategies exist to deal with
cases in which the reference standard result is missing in some patients … or when information can
be used to build a substitute or proxy for the reference standard, but when … there is no accepted
reference standard, other approaches have to be used.42
6
There are other
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
January 01, 2009 - The results of the test under evaluation are compared to those from a reference standard
in order to … standard or when the
new test is thought to be better than the current reference standard. … Strategies exist to deal with
cases in which the reference standard result is missing in some patients … or when information can
be used to build a substitute or proxy for the reference standard, but when … there is no accepted
reference standard, other approaches have to be used.42
6
There are other
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effectivehealthcare-admin.ahrq.gov/products/outcomes-research-depression/abstract
June 01, 2022 - findings and lessons learned from this project serve as a roadmap to support future work in AHRQ developed standards-based
-
effectivehealthcare-admin.ahrq.gov/products/standardized-libraries
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effectivehealthcare-admin.ahrq.gov/products/obesity-research-methods/systematic-review
November 01, 2019 - Research could be advanced by more use of data dictionaries, reporting standards on data linkage, long-term … environment changes on obesity prevention and control, such as consistent use of data dictionaries, reporting standards