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  1. www.uspreventiveservicestaskforce.org/Home/GetFile/1/16813/prostate-cancer-models-overview/pdf
    May 01, 2018 - For the PSAPC and SCANS models, the benefit of screening arises from a shift to an earlier stage of … cancer (stage shift) due to screening. … Allowing the risk of progression to distant stage to be different produced higher distant-stage but … similar local- regional stage incidence projections. … ‘Distant stage’ is the cancer spread (asymptomatic) utility (0.67), therefore 0.92- 0.67=0.25.
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/hWPZYvUZJXUQghbFtSDC42
    August 01, 2011 - to 70%) will recur after treatment, with a 10% to 20% risk for the tumor to progress to the invasive stage … associated with early treatment, which may occur more frequently with greater detection of cases of early-stage … bladder cancer has been diagnosed, several fac- tors determine treatment, including tumor grade, cancer stage … One challenge of screen- ing for bladder cancer is accurately identifying cases of early-stage cancer … As noted, prospective cohort studies are needed to more accurately identify cases of early-stage cancer
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-c-screening
    December 21, 2017 - include those defined by age, race/ethnicity, sex, drug use, receipt of maximally assisted therapy, stage … Populations Persons with screen-detected or asymptomatic HCV infection (patients with a METAVIR fibrosis stage … HCV transmission; and the population for antiviral treatment includes persons with a METAVIR fibrosis stage
  4. www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/2025-03/uspstf-who-we-are-how-we-work-2025.pdf
    January 01, 2025 - Topics can be searched by type of preventive service, population, publication date, and stage of recommendation … • We invite input at every stage. … Recommendation Statement The Task Force and EPC consider all comments submitted in the draft recommendation stage
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/za7BqXMwT8BMz4Z_ygrvKm
    May 01, 2004 - screening with serum CA-125 level or transvaginal ultrasound can detect ovarian cancer at an earlier stage … Furthermore, existing evidence that screening can detect early-stage ovarian cancer is insufficient to … abnormally elevated levels) reported that 50% of patients with ovarian cancer in the screened group were in Stage … using transvaginal ultrasound screening reported that 59% to 65% of ovarian cancers were diagnosed in Stage … I.11,12 However, there is no evidence that detecting earlier-stage tumors through screening leads to
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/LSbrGFWSvekVzhcxwjTuXv
    February 01, 2016 - For advanced cancer outcomes, studies that reported the incidence of late-stage disease among screened … These include stage III and IV dis- ease (i.e., regional and metastatic, respectively), size 40 to 50 … Studies provided heterogeneous measures of breast cancer severity and generally reported early-stage … Biennial versus annual mammography and the risk of late-stage breast cancer. … as stage IIA or higher; size ≥50 mm is classified as stage IIB or higher. ‡ Represents the highest category
  7. www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-screening-2001
    April 01, 2001 - In the elderly, melanoma tends to be diagnosed at a later stage and is more likely to be lethal than … Screening consistently identifies melanomas that are, on average, thinner (i.e., at an earlier stage) … It is not known if this stage shift leads to decreased morbidity or mortality. … Periodic total-body skin examination can increase the detection of thin (earlier stage
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/j-FyHoTDHNJu_qmotFzJq3
    February 15, 2001 - In the elderly, melanoma tends to be diagnosed at a later stage and is more likely to be lethal than … Screening consistently identifies melanomas that are, on average, thinner (i.e., at an earlier stage) … It is not known if this stage shift leads to decreased morbidity or mortality. … Discussion Periodic total-body skin examination can increase the detection of thin (earlier stage) melanoma
  9. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary14/bladder-cancer-in-adults-screening
    October 15, 2010 - Stage 2 tumors and higher are muscle-invasive. … proportion of patients with signs or symptoms suggesting bladder cancer, occupational exposures, the stage … only controlled cohort studies on screening suggest that screening might result in a shift to earlier stage … diagnosis: 43% (9 of 21) vs. 19% (99 of 511); RR, 2.2 (CI, 1.3-3.7) Muscle-invasive or higher-stage … screening for bladder cancer was associated with decreased risk for bladder cancer mortality or lower stage
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan97/breast-cancer-screening-january-2016
    July 17, 2014 - on intermediate breast cancer outcomes g (e.g., ductal carcinoma in situ [DCIS] detection rates, stage … Intermediate breast cancer outcomes include: interval breast cancer incidence, DCIS diagnosis rate, stage … KQ 10: Interval breast cancer incidence, DCIS diagnosis rate, stage at breast cancer diagnosis, invasive … value for: invasive breast cancer, breast lesions (DCIS), total breast cancer, and breast cancer by stage
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review48/hepatitis-b-in-pregnant-women-screening-2009
    June 15, 2009 - Both reviewers evaluated all articles at the abstract and full-text article stage on the basis of predetermined … Articles selected at the first stage by at least 1 reviewer were advanced to the next stage of review … At the full-text article stage, we resolved differences of opinion by a consensus process.
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/mEtSwJk3YPA4BXJ8eZyD2S
    June 01, 2009 - Both reviewers evaluated all articles at the abstract and full-text article stage on the basis of predetermined … Articles selected at the first stage by at least 1 reviewer were advanced to the next stage of review … At the full-text article stage, we resolved differences of opinion by a consensus process.
  13. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-vii-criteria-assessing-external-validity-generalizability-individual-studies
    July 01, 2017 - Stage or severity of disease: the selection of subjects for the study includes persons at a disease stage
  14. www.uspreventiveservicestaskforce.org/USPSTF_Admin/Home/GetFile/1/996/syphilup/pdf
    July 01, 2004 - Late-stage syphilis includes gummatous, cardiovascular, and neurological complications that can lead … The preparation, dosage, and length of treatment depend on the stage and clinical manifestations of disease … and delivered non-infected infants.27 High VDRL titers at treatment and delivery, earlier maternal stage … A study of the treatment of individuals exposed to a sexual partner with early- stage syphilis compared … The CDC recommends using the penicillin regimen appropriate for the stage of syphilis, despite the lack
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/L5UwXoftg4JHw4buVDhjUT
    October 01, 2010 - Stage 2 tumors and higher are muscle- invasive. … proportion of patients with signs or symptoms suggest- ing bladder cancer, occupational exposures, the stage … tar–pitch chemicals, there were nonstatistically significant trends toward a higher proportion of early-stage … screening for bladder cancer was associated with decreased risk for bladder cancer mortality or lower stage … only controlled cohort studies on screening suggest that screening might result in a shift to earlier stage
  16. www.uspreventiveservicestaskforce.org/uspstf/update-on-methods-insufficient-evidence---table-3
    February 01, 2009 - Melanomas detected at a late stage have a poor prognosis.
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/nNc2RNWq72TLentsPFw7WE
    Dosage and route may vary depending on the stage of disease and patient characteristics.
  18. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary46/skin-cancer-screening-2009
    February 15, 2009 - Does screening with whole-body examination or by self-examination detect melanomas at an earlier stage … Does screening with whole-body examination or by self-examination detect melanomas at an earlier stage … Does screening with whole-body examination or by self-examination detect melanomas at an earlier stage … remains whether encouraging skin self-examination would identify more lesions or lesions at an earlier stage … CQ2: Does screening with whole-body examination or by self-examination detect melanomas at an earlier stage
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/LgBN7_z7hqynt6BRzUUYA-
    February 01, 2009 - Does screen­ ing with whole-body examination or by self-examination detect melanomas at an earlier stage … Does screening with whole- body examination or by self-examination detect melano­ mas at an earlier stage … : Does screening with whole-body examination or by self-examination detect melanomas at an earlier stage … Does screening with whole-body examination or by self- examination detect melanomas at an earlier stage … remains whether encouraging skin self-examination would identify more lesions or lesions at an earlier stage
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/bladder-cancer-adults-screening-1996
    January 01, 1996 - Survival in patients with bladder cancer is strongly associated with stage … screening may have a limited potential for detecting lethal bladder cancers at an early, treatable stage … bladder cancer detected by screening were early tumors confined to superficial areas of the bladder (Stage … tumors become invasive early in the course of disease, and the potential to detect them at an earlier stage

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