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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RkeQEwKRWULreuWecXG8S-
    July 01, 2013 - Screening benefits are expressed in terms of the percentage of cancers detected at an early stage ( … The improved prognosis in Model E is represented as a cure fraction specific to stage at detection, … Model F estimates cure rates that depend on sex, tumor stage, and histology. … Mortality reduction due to screening is due to the earlier stage and younger age at detection. … early-stage cases are detected before this occurs.
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/677cVB3_YRhoEd3qakdjuS
    September 01, 2010 - Three studies were considered for inclusion at the full-text stage of review. … Articles selected for further examination by at least 1 author ad­ vanced to the next stage of review … At the full-text article stage, differences of opinion were resolved by consensus. … There­ fore, we will discuss the 3 articles that reached the full-text review stage (Table). … population: 5 Excluded study design: 4 Full-text articles reviewed (n = 3) Excluded at abstract stage
  3. www.uspreventiveservicestaskforce.org/uspstf/document/article/prostate-cancer-screening-2008
    August 05, 2008 - The USPSTF found good evidence that PSA screening can detect early-stage prostate cancer but found mixed … Articles selected by at least 1 reviewer advanced to the next stage of review. … We did not identify any population-based studies in which patients with stage T1c prostate cancer were … A recent report of a population-based cohort of men with untreated, early-stage prostate cancer found … reviewed (n = 6) Articles excluded at complete review stage (n = 3) Articles meeting inclusion
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/NhXnjZM5ubvygH5GrqDZHC
    August 01, 2008 - Articles selected by at least 1 re- viewer advanced to the next stage of review. … Fair Roemeling et al., 2006 (24) Prospective cohort 64 men with stage T1c or T2 prostate cancer, in … the first screening round of the Rotterdam section of ERSPC, who chose watchful waiting; 50 had stage … Articles excluded at title stage (n = 342) Articles identified by initial literature review (n = 390 … review stage (n = 3) Complete articles reviewed (n = 6) Articles meeting inclusion criteria (n =
  5. www.uspreventiveservicestaskforce.org/uspstf/recommendation/pancreatic-cancer-screening
    August 06, 2019 - Neoadjuvant or adjuvant chemotherapy may be recommended, depending on the stage of cancer and other factors … overall 5-year survival rate for pancreatic cancer is 9.3%, and survival rates vary depending on the stage … to improve chances of survival; however, most cases of pancreatic cancer are detected at an advanced stage … The remaining 4 cases were detected with advanced-stage nonresectable disease. … Twelve of the cases (66.7%) were detected at stage I or II or were classified as “resectable.” 12 , 13
  6. www.uspreventiveservicestaskforce.org/uspstf/recommendation/ovarian-cancer-screening-1996
    January 01, 1996 - Although pelvic examinations can occasionally detect ovarian cancer, 12 , 13 small, early-stage ovarian … CA-125 is elevated in 82% of women with advanced (Stage III or IV) ovarian cancer, 22 and it is also … elevated, although less frequently, in women with earlier stage disease. 23 In studies of women with … known or suspected ovarian cancer, the reported sensitivities of CA-125 in detecting Stage I and Stage … to provide more reliable data on the sensitivity of this and other tumor markers in detecting early-stage
  7. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/skin-cancer-screening
    July 26, 2016 - Measures: Melanoma incidence and mortality, harms from cancer screening, diagnostic accuracy, and stage … One good-quality study evaluated cancer stage and all-cause mortality. … Using the same study population and categorizing by SEER summary stage, distant stage was associated … After duplicates were removed, 12,061 unique citations were reviewed at the title/abstract stage. … II melanoma 9.99 (8.84–11.29) for stage III melanoma 27.1 (22.4–32.8) for stage IV melanoma
  8. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/skin-cancer-screening-july-2016
    July 26, 2016 - Measures: Melanoma incidence and mortality, harms from cancer screening, diagnostic accuracy, and stage … One good-quality study evaluated cancer stage and all-cause mortality. … Using the same study population and categorizing by SEER summary stage, distant stage was associated … After duplicates were removed, 12,061 unique citations were reviewed at the title/abstract stage. … II melanoma 9.99 (8.84–11.29) for stage III melanoma 27.1 (22.4–32.8) for stage IV melanoma
  9. www.uspreventiveservicestaskforce.org/uspstf/document/modeling-study/breast-cancer-screening
    April 30, 2024 - Treatment was assigned based on age, stage, and molecular subtype. … with digital mammography, although a reduction in advanced stage has not yet been demonstrated. 6 , … For example, some models incorporated a benefit from screening due to within-stage shift in detection … and subsequent treatment (models E, S, and W) while others required a stage shift (models D and GE) … distribution (AJCC or SEER Summary Stage) Stage distributions by mode of detection, age group (40-
  10. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/task-force-resources/uspstf-and-public-engagement
    April 01, 2021 - the USPSTF and its processes more transparent, the Task Force solicits public comments during each stage … The Task Force looks to the public during the final recommendation stage to share its recommendations
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/k2QHcwuK4NkvxFXhvGrbwY
    May 01, 2004 - indicated that although there was no direct evidence from prospective studies that women with early-stage … cancer in the U.S. is 50%, but may improve to 95% for women whose disease is detected and treated at stage … strategies are focused on increasing the proportion of cases detected in early stages, particularly stage … in a voluntary community screening program, reported that 58.8% of 85 ovarian cancers detected were stage … Approximately 65% of tumors in this study were stage I.
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/nmcMhEwWT9BncBBBQQN6Uf
    December 01, 2015 - If screen detection occurs, a new stage, possibly earlier than the clinical stage, is assigned to the … To do this, the model draws on distributions of stage dwell. … S(t) depends on age, stage, and ER/HER2 status. … Screening helps detect cancer in an earlier stage (stage shift). … This is called “beyond stage shift.”
  13. www.uspreventiveservicestaskforce.org/uspstf/recommendation/testicular-cancer-screening
    April 15, 2011 - consists of orchiectomy and may include other surgery, radiation therapy, or chemotherapy, depending on stage … Regardless of disease stage, over 90% of all newly diagnosed cases of testicular cancer will be cured … orchiectomy and may include other surgery, radiation therapy, and chemotherapy, depending on the disease stage … Regardless of disease stage, more than 90% of all newly diagnosed cases of testicular cancer will be
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan104/skin-cancer-screening
    July 17, 2014 - skin cancer screening leads to earlier detection of skin cancer tumors, specifically either an earlier stage … Comparison KQs 1, 2: No visual skin examination KQ 3: Biopsy KQ 4: Usual care KQ 5: Stage … false-positive results, false-negative results, cancer detection rates KQ 4: Lesion thickness or stage
  15. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan104/skin-cancer-screening-july-2016
    July 17, 2014 - skin cancer screening leads to earlier detection of skin cancer tumors, specifically either an earlier stage … Comparison KQs 1, 2: No visual skin examination KQ 3: Biopsy KQ 4: Usual care KQ 5: Stage … false-positive results, false-negative results, cancer detection rates KQ 4: Lesion thickness or stage
  16. www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/uspstf-public-engagement-fact-sheet-2021.pdf
    January 01, 2021 - Task Force and its processes more transparent, the Task Force solicits public comments during each stage … The Task Force looks to the public during the final recommendation stage to share its recommendations
  17. www.uspreventiveservicestaskforce.org/Home/GetFile/1/16255/collabmodelingbc/pdf
    December 01, 2015 - If screen detection occurs, a new stage, possibly earlier than the clinical stage, is assigned to the … To do this, the model draws on distributions of stage dwell. … S(t) depends on age, stage, and ER/HER2 status. … Screening helps detect cancer in an earlier stage (stage shift). … This is called “beyond stage shift.”
  18. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review79/ovarian-cancer-screening-2004
    May 15, 2004 - indicated that although there was no direct evidence from prospective studies that women with early-stage … U.S. is 50 percent, but may improve to 95 percent for women whose disease is detected and treated at stage … strategies are focused on increasing the proportion of cases detected in early stages, particularly stage … report estimated that approximately 50 percent (95% CI, 23-77) of ovarian cancers are diagnosed at stage … Approximately 65 percent of tumors in this study were stage I.
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/DcUgaNRhU6PvJWXqqsa8X7
    June 14, 2016 - Screening Tests There are numerous screening tests to detect early-stage colorectal cancer, including … Treatment and Interventions Treatment of early-stage colorectal cancer generally consists of local
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/VhSwc46MPwjDPNsgVrVm-B
    June 07, 2016 - Syphilis in- fection of the central nervous system (neurosyphilis) can occur at any stage of disease … Left untreated, syphilis can progress to late-stage disease in about 15% of persons who are infected. … Dosage and route may vary depending on the stage of disease and patient characteristics. … Dosage and route may vary depending on the stage of dis- ease and patient characteristics. … Syphilis infection of the nervous system (neuro- syphilis) can occur at any stage.

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