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effectivehealthcare.ahrq.gov/products/liver-cancer
July 25, 2013 - Imaging Techniques for the Surveillance, Diagnosis, and Staging of Hepatocellular Carcinoma (HCC)
Timeline
September 21, 2012
Topic Initiated
July 25, 2013
Research Protocol
Archived
Imaging Techniques for the Surveillance, Diagnosis, and Staging of Hepatocel…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
January 01, 2011 - Effective Health Care
Topic Number: 0407
Document Completion Date: 02-14-12
1
Results of Topic Selection Process & Next Steps
Primary diagnosis and staging of pancreatic cancer will go forward for refinement as a systematic
review. The scope of this topic, including populations, interventions, c…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
March 06, 2013 - How do tumor characteristics (stage, grade, multiplicity, size, molecular and genetic
alterations) … Initial treatment for this stage of
bladder cancer usually involves surgical removal of the tumor through
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - due to renal cell carcinoma are driven by the failure of systemic treatments
in metastatic (later stage … Localized renal cell carcinoma (stage T1N0M0, ≤ 7 cm in
diameter; stage T2N0M0, > 7 cm in diameter) … Given the increased incidence in early, low-stage tumors without improvement in cancer-related
deaths … T1, and > 85% for stage T2 tumors). … Kane, C.J., et al., Renal cell cancer stage migration: analysis of the National Cancer Data
Base.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-executive-summary.pdf
August 01, 2024 - insufficient to
• Evidence remains uncertain for other comparisons including local excision versus
CRT for stage … insufficient for remaining comparisons (not shown in Table A) including local excision
for early-stage
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - Common pressure ulcer sites
Stage: I
Intact skin with … Stage: III
Full thickness
tissue loss. … Stage: IV
Full thickness
tissue loss with
exposed bone,
tendon or
muscle. … Stage I is
defined as superficial erythema, stage II as partial thickness
ulceration, stage III as … used the
corresponding NPUAP stage in summary tables and text
when possible.
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effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
February 24, 2016 - The ES now reports stage-specific
outcomes.
b. … The Woldu paper also had too few patients (262 of 1306) in the Stage 3
group, with only 74 Stage 3B … Takagi showed
benefit of NSS for those with baseline GFR 45-59 (Stage 3A) but not
Stage 3B. … of stage III or
greater patients. … of stage III or greater patients.
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effectivehealthcare.ahrq.gov/products/prostate-cancer-therapies-update/research-protocol
March 29, 2013 - grouping) to determine the overall stage, which is commonly reported in Roman figures (Stages I, IIA … , IIB, III, and IV), with stage I being the least advanced and stage IV being the most advanced. … of 7, or a clinical stage of T2b but not qualifying for high risk
High risk (roughly corresponding … to stage IIB): a PSA level of more than 20 ng/mL, a Gleason score of 8–10, or a clinical stage of T2c … stratified by stage.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
April 01, 2013 - Lymph node (N) stages
Stage Description
NX Nearby lymph nodes were not assessed
N0 The cancer has … , IIB, III, and IV), with stage I being the least advanced and stage IV being the most
advanced. … for high risk
• High risk (roughly corresponding to stage IIB): a PSA level of more than 20 ng/mL, … Prostate cancer that is believed to be confined to the prostate gland (T1–T2, NX,
M0; or stage I–II) … not stratified by stage.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/anal-cancer-draft-report.pdf
October 31, 2023 - • Evidence remains uncertain for other comparisons including local excision versus CRT
for stage … Stage Definition
I T1 (tumor ≤2 cm in greatest dimension), no nodal involvement (N0), and no distant … of total sample), whereas the smaller
RCT (n=110)8 reported no cases of stage IV cancer at baseline … Treatment
compliance in early-stage anal cancer. … Management of Stage I
Squamous Cell Carcinoma of the Anal
Canal.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/liver-cancer_research-protocol.pdf
July 24, 2013 - all individuals with other
causes for cirrhosis (including alcoholic cirrhosis), and patients with stage … imaging techniques are available to
identify the presence of lesions, diagnose HCC, and determine the stage … There is clinical uncertainty about which imaging technique to use to diagnose and stage
HCC. … What is the comparative test performance of imaging techniques to predict HCC tumor
stage?
i. … Outcomes Diagnostic outcomes include:
• Measures for accuracy of staging (stage reclassification).
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
October 23, 2014 - Clearly the goal of any surveillance
program is the detection of a deadly disease at a curable stage … Peer Reviewer
#5
Introduction The introduction provides the necessary background to set the stage … Many of the studies
evaluating imaging for staging HCC have used the TNM stage, but this is
not the … For each stage of care, appropriate testing and
treatment are outlined. … That is, changes in
therapeutic management or stage reclassification are appropriate terminal
points
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effectivehealthcare.ahrq.gov/products/alzheimers-type-dementia/protocol
November 27, 2018 - Reasons for exclusion at this stage will be reported. … For individual CATD treatment studies, for each outcome of interest (i.e., stage, global cognition and … Based on the frequency with which they are reported, we will decide which specific stage, cognitive ( … than at CATD stage, so that recognizing CATD currently is a higher priority than recognizing MCI. … There was some TEP confusion about whether the protocol would look at CATD stage as a potential
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
November 02, 2018 - age, sex, race/ethnicity, education, depression, pre-treatment cognitive or
functional level/CATD stage … Reasons for exclusion at this stage will be reported. … Based on the frequency with which they are reported, we will decide
which specific stage, cognitive … than at CATD stage, so that recognizing CATD currently is a higher
priority than recognizing MCI. … Specified that we would
determine which validated
stage, cognitive,
functional, quality of life,
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effectivehealthcare.ahrq.gov/products/liver-cancer/research
October 23, 2014 - Current Page Topic Timeline Sep. 21, 2012 Topic Initiated Jul. 25, 2013 Research Protocol Oct. 23, 2014 Systematic Review Jan. 29, 2015 Disposition of Comments Report Imaging Techniques for the Diagnosis and Staging of Hepatocellular Carcinoma
Systematic Review Archived October 23, 2014 Web Version [NLM Site] Down…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/advanced-care-decision-aids_disposition-comments.pdf
July 29, 2014 - Framework: ACP (and thus tools for
ACP) vary by the target group’s stage of life and health. … These are real decisions for person in stage 1 of ACP
(healthy) and they are appropriately not focused … In stage one (healthy), a key index decision is “Who will
be my surrogate if one should be needed?” … For someone in stage three (advanced stage of
serious illness), a proxy decision is still critical if … At what stage of disease? Should the doctor
be allowed to initiate this discussion?
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
March 13, 2012 - I) to the upper abdomen (FIGO
Stage III).10 The possibility of rapid spread from the ovary means that … many cancers identified at
Stage I may represent a subgroup of less aggressive tumors rather than a … Ovarian cancer can either be detected at a given stage or progress
to the next stage prior to detection … I
cancer
Undetected
Stage I
cancer
Detected
Stage II
cancer
Undetected
Stage II
cancer … Detected
Stage III
cancer
Undetected
Stage III
cancer
Detected
Stage IV
cancer
Undetected
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/iron-deficiency-anemia-in-renal-dialysis-patients
June 17, 2008 - (For example, an ethnic group, stage or severity of a disease.) … Health Care Program
None
Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage
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effectivehealthcare.ahrq.gov/products/renal-disease-iron/abstract
January 24, 2012 - Comparative Effectiveness of Intravenous Iron Formulations in the Treatment of Anemia in End Stage Renal
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effectivehealthcare.ahrq.gov/products/bladder-cancer-muscle-invasive/research-protocol
July 21, 2014 - and adjacent structures. 5 Bladder cancers that have not invaded the bladder smooth muscle layer (stage … Stage 2 cancers are muscle-invasive, and higher stage cancers invade beyond the muscle layer into surrounding … fat (stage classification T3 bladder cancer). … Stage T4a cancers, which go beyond the fat into the prostate, vaginal wall, or uterus, are also still … Approximately 25 percent of newly diagnosed bladder cancers present as stage 2 or higher tumors. 6 Once