-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
August 09, 2013 - Once
pancreatic adenocarcinoma is diagnosed, the stage of disease is a key determinant of clinical … • We added the precise stage (stage IA, IB, IIA, IIB, III, or IV) to KQ 2 (staging) because
some … studies may report accuracy data based on stage (e.g., percentage of tumors judged
to be stage IB by … imaging and were later found to be stage IB during surgery) … • N stage
• M stage
• Stage I, II, III, or IV
• Vessel involvement
• Resectability
2b P2 Same
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
May 01, 2025 - An effective screening test will reduce the number of cancers
diagnosed at an advanced stage, and ultimately … KQ 2b: What is the effectiveness of screening with MCSTs on the cumulative
detection of late-stage cancer … (i.e., stage shift) overall and by cancer type? … 3: What is the accuracy of MCSTs for detection of cancer and does accuracy
vary by cancer type or stage … Noninvasive detection of any-stage cancer
using free glycosaminoglycans.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-surveillance_executive.pdf
December 01, 2011 - Stage
ii. Tumor volume
iii. Gleason score
iv. PSA
c. Diagnostic Strategies
i. … Tumor stage
Fifteen studies (covering 1969–2005) reported incidence
data, stratified by tumor stage … by tumor stage. … of prostate cancer
stage at diagnosis. … Consultant—second opinion
One survey was of men diagnosed with early-stage cancer.
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
February 01, 2016 - dependent, with a greater than 95 percent 5-year disease
specific survival for stage T1 tumors, and … greater than
85 percent 5-year disease specific survival for stage
T2 tumors. … 3, 3b, and/or
4 [or greater], and incidence of end-stage renal disease. … 3, chronic kidney disease stage 3b, end-stage renal disease,
as well as change in creatinine and … Renal
cell cancer stage migration: analysis of the National Cancer Data
Base.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
September 23, 2014 - Peer Reviewer 2 Discussion EUS is clearly superior in T stage assessment. … Trying to define T stage is useless. … About T
stage, we included it only because it was one facet
of clinical stage, even though its importance … For each stage of care, appropriate
testing and treatment are outlined. … We also concluded “US-FNA
is more accurate than MDCT in the assessment of
the T stage of pancreatic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-draft-appendix-d1.xlsx
January 01, 2024 - Randomized Overall NCCN risk group Intervention Group NCCN risk group Control group NCCN Risk group Cancer stage … overall Cancer stage intervention group 1 Cancer stage intervention group 2 PSA level overall PSA … Age ≥18 years, unfavorable intermediate- or favorable high-risk prostate cancer, ≥1 of risk factors stage … Not reported Multiple Age >18 years, histologically confirmed prostate adenocarcinoma, clinical stage … Inclusion criteria were stage T3b-T4a; T1-T3a with Gleason Score (GS) 8–10; T1-T3a with GS 7 and serum
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-disposition-comments.pdf
May 14, 2025 - direct evidence from industry studies that
detectable cancers are more aggressive
within the same stage … Review
authors also calculated a statistically
significant reduction in Stage III or IV cancer
in … One of the most considered is
reduction in advanced stage cancer burden,
referred to as “stage shift … A related
approach is recurrence-updated stage
shift5. … (i.e., stage shift) overall
and by cancer type?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - due to renal cell carcinoma are driven by the failure of systemic treatments
in metastatic (later stage … Localized renal cell carcinoma (stage T1N0M0, ≤ 7 cm in
diameter; stage T2N0M0, > 7 cm in diameter) … Given the increased incidence in early, low-stage tumors without improvement in cancer-related
deaths … T1, and > 85% for stage T2 tumors). … Kane, C.J., et al., Renal cell cancer stage migration: analysis of the National Cancer Data
Base.
-
effectivehealthcare.ahrq.gov/products/anal-cancer-treatment/research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - Common pressure ulcer sites
Stage: I
Intact skin with … Stage: III
Full thickness
tissue loss. … Stage: IV
Full thickness
tissue loss with
exposed bone,
tendon or
muscle. … Stage I is
defined as superficial erythema, stage II as partial thickness
ulceration, stage III as … used the
corresponding NPUAP stage in summary tables and text
when possible.
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_disposition-comments.pdf
February 24, 2016 - The ES now reports stage-specific
outcomes.
b. … The Woldu paper also had too few patients (262 of 1306) in the Stage 3
group, with only 74 Stage 3B … Takagi showed
benefit of NSS for those with baseline GFR 45-59 (Stage 3A) but not
Stage 3B. … of stage III or
greater patients. … of stage III or greater patients.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_disposition-comments.pdf
October 23, 2014 - Clearly the goal of any surveillance
program is the detection of a deadly disease at a curable stage … Peer Reviewer
#5
Introduction The introduction provides the necessary background to set the stage … Many of the studies
evaluating imaging for staging HCC have used the TNM stage, but this is
not the … For each stage of care, appropriate testing and
treatment are outlined. … That is, changes in
therapeutic management or stage reclassification are appropriate terminal
points
-
effectivehealthcare.ahrq.gov/products/anal-cancer-treatment/protocol
-
effectivehealthcare.ahrq.gov/products/chronic-kidney-disease-anemia-2011/research-protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
April 01, 2013 - Lymph node (N) stages
Stage Description
NX Nearby lymph nodes were not assessed
N0 The cancer has … , IIB, III, and IV), with stage I being the least advanced and stage IV being the most
advanced. … for high risk
• High risk (roughly corresponding to stage IIB): a PSA level of more than 20 ng/mL, … Prostate cancer that is believed to be confined to the prostate gland (T1–T2, NX,
M0; or stage I–II) … not stratified by stage.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-executive-summary.pdf
August 01, 2024 - insufficient to
• Evidence remains uncertain for other comparisons including local excision versus
CRT for stage … insufficient for remaining comparisons (not shown in Table A) including local excision
for early-stage
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
January 01, 2011 - Effective Health Care
Topic Number: 0407
Document Completion Date: 02-14-12
1
Results of Topic Selection Process & Next Steps
Primary diagnosis and staging of pancreatic cancer will go forward for refinement as a systematic
review. The scope of this topic, including populations, interventions, c…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
March 13, 2012 - I) to the upper abdomen (FIGO
Stage III).10 The possibility of rapid spread from the ovary means that … many cancers identified at
Stage I may represent a subgroup of less aggressive tumors rather than a … Ovarian cancer can either be detected at a given stage or progress
to the next stage prior to detection … I
cancer
Undetected
Stage I
cancer
Detected
Stage II
cancer
Undetected
Stage II
cancer … Detected
Stage III
cancer
Undetected
Stage III
cancer
Detected
Stage IV
cancer
Undetected
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
March 06, 2013 - How do tumor characteristics (stage, grade, multiplicity, size, molecular and genetic
alterations) … Initial treatment for this stage of
bladder cancer usually involves surgical removal of the tumor through
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
October 01, 2012 - 5 experts thought this conclusion was still
valid. 1 cited a study21 stating separate data
on CKD stage … Congestive Heart Failure; CKD=Chronic Kidney Disease; eGFR=Epidermal growth factor receptor; ESRD=End-Stage … fruits and
vegetables OR oral
sodium bicarb OR
no intervention
27 Hypertensive nephropathy
at stage … 1 or 2 eGFR
Indices of kidney injury 30 days Indices of kidney injury were not changed in
Stage 1 … However, stage 2 patients
decreased urinary albumin, N-acetyl B-D-
glucosaminidase and transforming