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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
    September 02, 2011 - Data Extraction and Data Management Determine Outcomes To Extract Specific outcomes to extract … We will make these judgments for each of the main KQs and any subquestions related to specific outcomes … bias is derived from the quality assessment of the individual studies which addressed that KQ and specific … as needed by the EPC with input from Key Informants and the TEP to assure that the questions are specific … They are selected to provide broad expertise and perspectives specific to the topic under development
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
    March 19, 2018 - TEP reviewer #3 No specific comments on this section. … The specific domains which contributed to the downgrading of all outcomes, organized per KQ, appear … It may be more specific to state that the intermittent dosing is defined as a change in dosing with … Conclusions are always solidly based on the specific KQs and on an objective assessment of the data … We have added subheading to break up the lengthy discussion to identify specific KQ.
  3. effectivehealthcare.ahrq.gov/products/methodological-recommendations-framework-communications/research
    September 09, 2013 - Finally, giving specific methods guidance for addressing difficult or ill-defined problems can be premature
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_disposition-comments.pdf
    March 01, 2012 - Specific reference to the use of embolic protection devices in saphenous vein grafts has been added … E.g. specific outcomes in rows, covariates in columns and available evidence (pooled or otherwise) in … We have organized the report according to the specific population (STEMI vs. other ACS) for several … There are references to specific device names that were used in specific trials, which was commonly … done in the event there was only one trial evaluating the specific outcome/comparison.
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-protocol-amended.pdf
    June 10, 2018 - Many unidimensional and multidimensional pain assessment scales are available including specific scales … for a variety of pain conditions10-13 and for specific sub- populations.14-17 Multidimensional assessment … We will construct search strategies to identify original research on specific acute pain conditions … Information Management Evidence tables specific to each priority acute pain condition will be created … • Are you aware of clinical practice guidelines addressing specific common acute pain conditions?
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiotherapy-proton-beam_research.pdf
    May 01, 2012 - proton beam radiotherapy has gained acceptance based on a theo- retical advantage for the treatment of specific … CMS has yet to issue a national coverage rule for proton beam therapy or its specific indications. … proton beam radiotherapy along with external beam radiotherapy in general but without identifying specific … one of the LCDs. *** These indications appear in the claims but are not covered in the LCDs listing specific … DISCUSSION As a highly specific form of advanced radiotherapy, proton beam therapy may play an important
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
    September 02, 2016 - spur pediatric research, children remain “therapeutic orphans” 12 for whom a paucity of pediatric-specific … Appendix A includes the literature searches from the original report and the specific search strategies … o Sociodemographic risk factors KQ 1: Children with chronic OME (allow study-specific definitions of … Global and otitis-specific child and parental quality of life 2. Speech and language outcomes 3. … Global and otitis-specific child and parental quality of life o Intermediate outcomes 1.
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
    November 24, 2014 - This specific question relates to risk of bias considerations (rather than grading strength of evidence … Specific recommendations for study design, dosing, monitoring antibiotic levels should be included … believe that a recommendation this specific is applicable. … Peer Reviewer #2 Discussion/ Conclusion More discussion of MICs and specific organisms in the … Is there a way to advise in the power and the specific outcomes that need to be measured?
  9. effectivehealthcare.ahrq.gov/products/prostate-cancer-therapies-update/research-protocol
    March 29, 2013 - These presenting symptoms along with a physical examination, prostate-specific antigen (PSA) levels, … The cancer is identified by needle biopsy, which is performed because of high prostate-specific antigen … Details (specific search terms and search strategies) are provided in Appendix A of this protocol. … Prostate-Specific Antigen Best Practice Statement: 2009 Update. … They are selected to provide broad expertise and perspectives specific to the topic under development
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol-2014.pdf
    January 01, 2014 - As recommended by the Methods Guide for Medical Test Reviews,11 the searches will not use filters specific … Manufacturers of diagnostic equipment (polarizing microscopes) will be contacted for unpublished data specific … This input is intended to ensure that the key questions are specific and relevant. IX. … They are selected to provide broad expertise and perspectives specific to the topic under development … provide information to the EPC to identify literature search strategies and recommend approaches to specific
  11. effectivehealthcare.ahrq.gov/products/patient-safety-databases-prescriptions/research
    August 26, 2008 - Sex-specific analysis. … Sex-Specific Analysis Of the 880 female-specific diagnoses, only 11 (0.1 percent) occurred in males … No male-specific disorders were identified in females. … Not Female-Specific Female-Specific Female 93,784 869 94,653 69.36% 0.64% 70% Male … If we focus on more granular outcomes by examining specific drugs and/or specific adverse event codes
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/inguinal-hernia_research-protocol.pdf
    August 15, 2011 - Within each of these categories, several specific procedures have been employed. … Non-sutured “tension-free” surgical mesh gained in popularity, and many specific open procedures were … Specific aspects about mesh repair that may influence outcomes are the type of mesh (e.g., lightweight … These mesh-specific issues are covered by specific Key Questions (see Key Questions below). … Procedure category, specific procedure, specific mesh (if applicable), fixation method (if applicable
  13. effectivehealthcare.ahrq.gov/products/antiplatelet-treatment/research-protocol
    November 22, 2011 - The observation that specific CYP2C19 variants or levels of on-treatment platelet reactivity above a … Other potential modifiers of the utility of genetic and phenotypic test results include the specific … The precision of estimates of analytic validity depends on the specific statistic used; generally, a … Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug … On some specific reports, such as reports requested by the Office of Medical Applications of Research
  14. effectivehealthcare.ahrq.gov/products/ptsd-adult-treatment/research-protocol
    December 20, 2011 - Subsequently, the selection of specific psychotherapies, or specific pharmacologic interventions, may … Eclectic psychotherapy refers to a general class of therapies rather than to a specific intervention … They are selected to provide broad expertise and perspectives specific to the topic under development … Requires patient to associate each symptom with a specific traumatic event. 15-minute administration … There are three versions of the PCL: PCL-M (military), PCL-C (civilian), and PCL-S (specific). 5–10
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
    June 01, 2012 - Research during the 1970s and 1980s suggested that domain-specific training may be insufficient to … In addition, many treatments target specific functional difficulties regardless of etiology. … • Only included impairment-specific interventions. … Other programs described outreach to TBI survivors;40 community-based care;36 specific approaches to … Further guidance that would match measures most appropriate for specific patients and interventions
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-strength-evidence.ppt
    June 01, 2012 - Grading the strength of evidence Challenges specific to diagnostic tests Principles of grading the strength … Challenges Specific to Diagnostic Tests (1 of 2) Singh S, Chang SM, Matchar DB, et al. … Challenges Specific to Diagnostic Tests (1 of 2) One common challenge faced by reviewers of diagnostic … Challenges Specific to Diagnostic Tests (2 of 2) Singh S, Chang SM, Matchar DB, et al. … Challenges Specific to Diagnostic Tests (2 of 2) A second challenge faced by reviewers is applying the
  17. effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-strength-evidence.ppt
    June 01, 2012 - Grading the strength of evidence Challenges specific to diagnostic tests Principles of grading the strength … Challenges Specific to Diagnostic Tests (1 of 2) Singh S, Chang SM, Matchar DB, et al. … Challenges Specific to Diagnostic Tests (1 of 2) One common challenge faced by reviewers of diagnostic … Challenges Specific to Diagnostic Tests (2 of 2) Singh S, Chang SM, Matchar DB, et al. … Challenges Specific to Diagnostic Tests (2 of 2) A second challenge faced by reviewers is applying the
  18. effectivehealthcare.ahrq.gov/products/cad-women-diagnosis/research-protocol
    December 08, 2010 - Exercise ECG has been recognized in the literature as being less sensitive and specific for diagnosing … Despite sex-specific limitations, existing ACC/AHA guidelines propose that evidence of sex-specific limitations … which is summarized below. 7 These recommendations are made for the general population and are not specific … Grading will be outcome-specific; thus, a given study may be graded to be of different quality for two … Technical Expert Panel (TEP) A TEP panel is selected to provide broad expertise and perspectives specific
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
    June 28, 2013 - We have added in tamponade as a specific adverse event in the figure as suggested. … TEP #1 ES (Discussion/ Conclusion) Specific comments: 1. … We do however now list the specific guideline reference for Figure 1 as suggested. … TEP #6 Introduction No specific concerns Thank you. … In addition, the data is insufficient for this specific comparison/outcome.
  20. effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-patients-with-chronic-diseases-where-large-numbers-of-physicians-do-not-follow-guideline-based-care-such-as-with-asthma-the-most-common-chronic-disease-what-are-the-most-and-least-effective-interventions-to-modify-physici
    July 16, 2010 - submitted: July 16, 2010 Download Topic Suggestion Disposition [PDF · 180.2 KB] Briefly describe a specific … yes If yes, explain the specific technologies, devices, drugs, or interventions you would like to … (Please include specific details such as age range, gender, coexisting diagnoses, and indications for

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