-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/erythropoiesis-stimulating-agents-utilization_research.pdf
February 01, 2011 - An extremely small proportion of non-KD
beneficiaries used ESAs (<0.4%), and this proportion decreased … A small proportion
of cancer only beneficiaries used ESAs; use
declined from 6 percent to about 2 percent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
July 01, 2017 - predictive value: 99.8%
Negative predictive value: 68.5%
Nondiagnostic rate: 14%
���
Harms 16 (2,422)b A small … results NA ���
Local recurrence-free
survival
2 (217) Better results with RN, but all studies had a
small
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-risk-of-bias.pdf
December 01, 2017 - reconciliation method
• Reviewers must be trained
• Pilot test assessment of risk-of-bias tools using a
small … Pilot test assessment of risk-of-bias tools using a small subset of studies that are likely to represent
-
effectivehealthcare.ahrq.gov/sites/default/files/data-points-6-tables.xls
January 01, 2006 - population)
by Class of Drug and Active Ingredient, 2006-2009
Note: A single period (.) signifies a small … 0.50
Other Immunosuppresives CYCLOSPORINE 7.45 7.32 7.19 7.07
Note:a single period (.) signifies a small … population)
by Class of Drug and Active Ingredient, 2006-2009
Note: A single period (.) signifies a small … Other Immunosuppresives CYCLOSPORINE 81.38 79.12 77.58 73.12
Note:a single period (.) signifies a small … population)
by Class of Drug and Active Ingredient, 2006-2009
Note: A single period (.) signifies a small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_executive.pdf
February 01, 2012 - We excluded case-control studies,
meeting presentations, and very small (<10 patients)
studies. … For ultrasound, in 2006 we evaluated a relatively small set
of studies of B-mode grayscale ultrasound … Macromolecular
contrast medium (feruglose) versus small molecular contrast
medium (gadopentetate) enhanced … contrast-enhanced power Doppler
sonography using a microbubble echo-enhancing agent in
evaluation of small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-fatigue_executive.pdf
July 01, 2016 - Most studies enrolled
predominantly female patients, had small sample sizes, and
were conducted in … specialty clinics based on
the CDC (Fukuda, 1994) or Oxford (Sharpe, 1991) case
definitions, had small … Available studies generally enrolled
small numbers of participants, and many treatment trials
were … too small to detect significant differences between
groups.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-comments_0.pdf
October 11, 2019 - We agree that small number of studies per meta-
analysis is an issue. … Comment Response
Peer reviewer #4 General Comments Statistical issues: When the number of studies is small … doesn’t always
converge and may overestimate the confidence
intervals when the number of studies is small … We agree that small number of studies per meta-
analysis is an issue.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-disposition-comments.pdf
August 29, 2023 - TEP #2 General comments A summary table that is small, understandable and at 30k feet
might be worth … Peer Reviewer #2 Results The authors state that SF EBRT is associated with a small
decrease in overall
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-executive.pdf
December 01, 2009 - to remove the entire lesion during
the biopsy procedure (excisional biopsy) if the lesion is
fairly small … A core-needle biopsy is a procedure that involves
removing small samples of breast tissue through a
hollow … For others, the greater safety and less
invasive nature of core-needle biopsy are worth a small
sacrifice
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
March 13, 2012 - In this group, adjuvant chemotherapy may produce a small improvement in
overall survival when compared … with surgery alone, and it may afford a small reduction
in the risk of disease recurrence. … The data indicate that MMR
deficiency or high microsatellite instability (MSI-H) may identify a small
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
February 01, 2019 - same system as in the 2018 AHRQ noninvasive treatment for chronic pain review,13
recognizing that small … A small/slight effect was defined for pain as a mean between-group
difference following treatment of … The clinical
relevance of effects classified as small/slight might vary for individual patients depending
-
effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
October 01, 2007 - Addition-
ally, trials are often too short or too small to detect harms that
are rare or which emerge … patients might place a higher value on
preventing a stroke, but they would also need to consider the
small … Individual RCT and meta-analysis26,28 Net benefits emerge at 2 yr but are small (100
operations to prevent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
September 01, 2014 - does
not always differentiate malignant from benign pancreatic
lesions, and its ability to detect small … tumors or small
hepatic/peritoneal metastases is limited. … The
evidence base in both reviews was small: four or five
studies each. … patients without
jaundice that same test is worse), and tumor characteristics
17
(e.g., for staging small … Trikalinos TA, Hoaglin DC, Small KM, et al.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/phenylketonuria_research-protocol.pdf
March 29, 2011 - Published Online: March 29, 2011
EPC Protocol – Version 8 – 12.22.10
Scan of the Literature
A small … effectiveness using traditional statistical methods, we will use
appropriate methods for studies with small … anticipate that the evidence garnered from the literature search described above will
consist of small … Scan of the Literature
A small body of literature reports on aspects of treatment of PKU; initial searches … We anticipate that the evidence garnered from the literature search described above will consist of small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_executive.pdf
April 01, 2012 - The exception was
a single study that showed that lower-dose sertraline
had some small improvement … antipsychotics (olanzapine, risperidone,
ariprazole, quetiapine) used as augmenting agents, which
showed small … The second trial evaluated
a dose escalation of fluoxetine in a small sample, and was
suggestive of … A second study, a pilot with small
sample size evaluating dose escalation, showed no effect. … Phenytoin as an
augmentation for SSRI failures: A small controlled study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/procalcitonin_executive.pdf
October 01, 2012 - The pool of
studies was too small to permit meaningful subgroup
and sensitivity analyses. … A second study22
(n=72) was judged too small to be informative. … of evidence was judged insufficient to make
conclusions on mortality and morbidity because of the
small … The evidence consisted of one small
(n=20) trial.33
Discussion
Clinical Context and Applicability … Although this was a small study,
it suggests that this approach might identify a group
who would benefit
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - chose to swim may be less likely to report minor degrees
of otorrhea).
15
Overall, aside from the small … The changes in the disease-specific health-related quality-
of-life scores at 2 weeks were small but … We were
unable to provide pooled results due to the small number
of studies, multiple interventions … systematically
excluded from comparative trials, limiting the applicability
of the evidence to these and other small … However, a nuanced
understanding of which children may benefit from
adenoidectomy is limited by the small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - • Limits: There were small sample sizes in all but one trial; few trials reported
most outcomes … • Limits: Sample size was small; there were few clinical events; no data were
reported for mortality … • Limits: This was a small trial; there were few outcomes. … • Limits: This was a small trial with few deaths; no data were reported for clinical
vascular … clinical outcomes in
patients with CKD stages 1–3 is unclear because diet
intervention RCTs were small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_executive.pdf
September 01, 2013 - We used Egger’s
regression-based test37 to assess the presence of small-
study effects.37,38
Strength … We considered evidence to be sparse if it was from only
one study with a small sample size. … Asian
ethnicity; however, this finding needs to be interpreted with
caution, given the relatively small … The sixth
study was a small genetic substudy of 126 patients that
reported no major bleeding events … Our confidence in these
findings is limited by the relatively small number of studies
available for
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/case-management_executive.pdf
January 01, 2013 - The sample sizes of the studies of CM were variable,
but many of the studies included fairly small samples … Due to heterogeneity in the characteristics of CM
interventions and the limitation of small sample sizes … across studies,
and overall, the improvements in QOL and functional
status achieved by CM were either small … Because studies comparing CM with usual care have
generally found only small differences in important