-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
October 01, 2019 - Mucolytics
may have a small effect on reducing the frequency
of ECOPD.22, 23 In clinical practice, … need
for hospital admission and improve health-related
quality of life based on single studies with small … majority of studies were conducted in
hospitalized patients with moderate or severe
ECOPD with only a small … As these findings were based on
single, relatively small studies, evidence from well-
conducted large … prescribed in
patients hospitalized for ECOPD, but there was
insufficient evidence (from relatively small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4.pdf
January 01, 2023 - The new study was assessed as high risk of bias and
had a small sample size (n=60).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_disposition-comments.pdf
May 24, 2013 - patients with small accessible tumors are candidates for ablation
whereas more extensive disease would … While combination therapies represent a small proportion of the
treatments for these patients we felt … patients with small accessible tumors are candidates for ablation
whereas more extensive disease would … The principle reason
is in the approach to the 'lesions' - if small <3cm
and accessible the default … with different disease characteristics are candidates for different
treatments (e.g. patients with small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
January 01, 2013 - The exception was a
single study that showed that lower-dose
sertraline had some small improvement … antipsychotics (olanzapine,
risperidone, aripiprazole, quetiapine) used as
augmenting agents, which showed small … Health
Canada/MHRA (UK)
Expert Opinion
EPC Investigator Other
Experts
Conclusion
from SCEPC
small … The exception was a
single study that showed that lower-dose
sertraline had some small improvement … The
second trial evaluated a dose escalation of
fluoxetine in a small sample, and was
suggestive of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
November 01, 2012 - This is primarily due to single, relatively
small trials comparing pairs of active treatments. … There is a relatively small body of evidence for the
parenteral treatment of acute migraine headache … in the ED
setting, and the evidence arises from small studies, usually
from single centers. … A small number of studies and overall small sample sizes
contributed to imprecision. … We checked the data for
inconsistency and found that the number of inconsistent
nodes was small.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-276-ocd-executive-summary.pdf
December 01, 2024 - After removing small RCTs (N <
100 participants) that evaluated novel comparators, e.g., variations … Limitations
Multiple small studies reported novel comparisons sizes that did not support graded
conclusions
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1306.pdf
October 01, 2014 - a systematic process that involves compiling
information on topics and issuing topic drafts to a small … to improve patient
outcomes, but a few noted that the target population for this intervention is small … However, they moderated this
opinion somewhat because of the relatively small number of patients who … Experts agreed that this intervention would have dramatic cost impacts for the small population
for … period] had large and
rapid antidepressant effects with[in] 24 hours of administration in several small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
August 01, 2013 - Anxiety
symptoms
136 Insufficient for LLLT A single study with high risk of bias and small sample … Depression
symptoms
136 Insufficient for LLLT A single study with high risk of bias and small sample … Small sample sizes led
to these studies being considered imprecise. … Sample sizes
tended to be small (<100 persons), and power calculations
were largely absent from the … In
general, SOE for TSQoL is rated as insufficient based on
the high risk of bias, and the small sample
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
December 14, 2010 - the stomach with an
implanted medical device; Roux-en-y gastric bypass (RYGB), which re-routs the small … intestine to a small stomach pouch; biliopancreatic diversion with duodenal switch
(BPD/DS), which … redirects the pancreatic/biliary content flow and constructs a small
stomach tube; and sleeve gastrectomy … Gastric bypass: A surgical weight-loss procedure that involves the creation of a
small stomach pouch … www.effectivehealthcare.ahrq.gov
Published Online: December 14, 2010
duodenum and other segments of the small
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
May 01, 2016 - Core-needle procedures, which remove a small tissue sample
through a very small incision, have been
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
April 10, 2020 - evidence for non-
pharmacological interventions was based on single (as opposed to
pooled) RCTs with small … “Abstract: Evidence on benefits of
psychotherapy arose from single small
studies. … monotherapy may
not match combined therapy for those
without ADHD but these findings arise from
small … monotherapy may
not match combined therapy for those
without ADHD but these findings arise from
small … these interventions, they rated as
insufficient because these single studies
for each modality were small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-information-exchange_executive.pdf
December 01, 2015 - Studies were of a small number of the
functioning HIE implementations, with
similarity to unstudied … which studies
of 12 different HIE implementations are the most frequent
even though they represent a small … Fewer studies were based
on national surveys/datasets, and a comparatively small
number of studies … affect practice and
numerous outcomes; however, evaluation studies have
focused on only one or a small … Health
information exchange in small-to-medium sized family
medicine practices: motivators, barriers,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
March 01, 2009 - Trial N too small
B-7
85. Crowell EB, Jr., Jubelirer SJ. … Trial N too small
138. Gluck O, Maricic M. … Trial N too small
188. Lo SS, Vogel VG. … Trial N too small
218. Olevsky OM, Martino S. … Trial N too small
275. Tchou J, Morrow M.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_disposition-comments.pdf
October 01, 2012 - This report is much
smaller in scope and really is limited to analysis of a
small set of measures. … First, the small number of studies that embrace the CQI
framework. … Second, virtually small number of studies that actually
has hospice as the site of care. … I have
made a few general comments in an up-loaded
attachment file that pertains to small points in … Remind the reader that The percentiles are
based on only a small number of studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_disposition-comments.pdf
November 07, 2012 - In both the community and nursing
homes, individuals are allowed to keep only a small amount of
financial … With the small
number of studies and limited samples, we felt
that this information was uninformative … One small critique -- the last paragraph
of the introduction needs to be modified. … Our conclusions
were limited given the small number of studies
and the weaknesses of those studies. … In this case, the increased
cost of the new users may more than offset what may be relatively
small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
April 17, 2024 - These forms will be refined through a pilot phase
involving a small set of studies to ensure they adequately … Estimates below the threshold for a small effect will
be categorized as “no effect.”23-25 Results with … a small, medium, or large effect that do not achieve
statistical significance will be considered to … Definitions of effect sizes
Effect size Definition
Small effect MD 0.5 to 1.0 points on a 0 to 10- … Fiducial markers: Small markers placed in or near the tumor to help guide and precisely target radiation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
March 01, 2012 - Randomization among a relatively small
number of clusters requires planning so as to address the need … Size of the
study sample may range from small to very large. … Small studies may involve one or a few
providers or practices and may approximate case studies. … Study size can be
small to large, depending on the intervention and the availability of data. … Study size may be small or large, depending on the intervention or the
availability of data.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-results-search-strategies-developed-with-without-text-mining-tools.pdf
March 01, 2021 - Results: Across all reviews, UP searches seemed to perform better than TMT, but because of the
small … Again, the small sample size precludes
significance
• TMTs neither affected search evaluation time … Because of the small sample size, the analysis
was limited to descriptive measures, including means, … Due to the
brevity and small number of comments a full content analysis was not performed; however, … The research base on these tools is very small, with very few
studies on any specific tool.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
January 01, 2007 - due to restrictive patient eligibility or
inadequate reporting; and limited power of studies due to small … rates of cardiovascular events between
interventions; however, it is likely that the studies were too small … Notably, the trials were small and
clearly too small to be adequately powered for clinical outcomes … However, it is clear that various complications after
revascularization do occur in a small percentage … • Although studies were generally too small to detect any but large differences
in mortality rates
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
February 01, 2013 - We found a very small number of relevant studies (Table 1).5-8 The most relevant example
was a prospective … Although the amount of evidence is small to confirm the presence of bias, the potential for bias is … Exclusion of small studies may
exclude valuable information. … Exclusion of small studies introduce
bias such as by excluding studies
conducted in nonacademic or … interventions may be smaller than studies on pharmaceuticals, thus biasing a review that
excludes small