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21. Executive Summary - Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2023 Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
    January 01, 2023 - <6 months): • Comparable plant-extracted THC to CBD ratio oral spray is probably associated with small … • Synthetic THC (high-THC to CBD) may be associated with small improvement in pain severity, but … Estimates that were below the threshold for a small effect were categorized as “no effect.”9,10 Table … Definitions of effect sizes Effect Size Definition Small effect • MD 0.5 to 1.0 points on a 0 to 10 … effect (7) [] Small effect (6) [] High THC – Synthetic, Oral Insufficient (2, 1 new)c

22. Systematic Review on Noninvasive Nonpharmacological Treatment for Chronic Pain: Surveillance Report 2 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-2-noninvasive-nonpharma.pdf
    April 01, 2022 - UC, AC, or placebo Function, short term Small improvement SOE: Moderate 10 RCTs (N=940) *2 … term Small improvement SOE: Moderate 3 RCTs (N=1,026) *1 fair-quality RCT (N=116)8 Moderate … in conclusions Pain, intermediate term Small improvement SOE: Moderate 3 RCTs (N=1,026) 1 … fair-quality RCT (N=116)8 Small improvement No change in conclusions Pain, long term Small … evidence 2 RCTs (N=109) *1 good-quality RCT (N=84)20 Small improvement Small improvement SOE

23. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-nonsurgical-therapies_research-protocol.pdf
    February 22, 2012 - The role of radiation therapy in non-small cell lung cancer. … Lung"[Mesh] OR ("Lung Neoplasms"[Mesh] OR "lung cancer") AND ("non-small-cell" OR "non-small cell" … Lung"[Mesh] OR ("Lung Neoplasms"[Mesh] OR "lung cancer") AND ("non-small-cell" OR "non-small cell" … lung cancer'/exp OR ('lung neoplasms'/exp OR 'lung cancer'/exp AND ('non- small-cell' OR 'non-small … lung cancer'/exp OR ('lung neoplasms'/exp OR 'lung cancer'/exp AND ('non- small-cell' OR 'non-small

24. Executive summary_Comparative Effectiveness Review No. 250_Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2024 Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
    January 01, 2024 - as described in • Extracted, comparable THC to CBD ratio oral spray is probably associated with small … Estimates that were below the threshold for a small effect were categorized as “no effect.”5,6 Table … Definitions of effect sizes Effect Size Definition No effect/trivial effect • Below thresholds for small … effect Small effect • MD 0.5 to 1.0 points on a 0 to 10-point scale, 5 to 10 points on a 0 to 100-point … d Potential effect: SOE of low or higher; findings indicate at least a small magnitude of effect but

25. What is the comparative effectiveness of conventional CT, MDCT (including “virtual CT bronchoscopy”), PET/PET-CT, and MRI for the diagnosis or pretreatment staging of small cell and non-small cell lung cancer? | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-conventional-ct-mdct-including-virtual-ct-bronchoscopy-petpet-ct-and-mri-for-the-diagnosis-or-pretreatment-staging-of-small-cell-and-non-small-cell-lung-cancer

26. Executive summary_Comparative Effectiveness Review No. 274: Diagnosis and Treatment of Tethered Spinal Cord (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-274-tethered-spinal-cord-executive-summary.pdf
    October 01, 2024 - • A small number of existing studies indicated benefits of prophylactic surgery for motor function … • A very small body of evidence exists for revision detethering and spinal column shortening for … A small body of evidence evaluated prophylactic surgery and indicated benefits for motor function and … A very small body of evidence exists for revision detethering and spinal column shortening for repeat

27. Evidence Summary: CER 231 Care Interventions for People Living With Dementia and Their Caregivers (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-231-dementia-interventions-evidence-summary_0.pdf
    August 01, 2020 - (low-strength evidence) The literature does not allow for further determination of whether the very small … to small average effects applied to all enrolled PLWD or if larger effects were concentrated in an unidentified … The vast majority of studies had small sample size, were pilots that had not undergone traditional efficacy … The goal may in fact be to slow the rate of burden—and studies may be underpowered to detect such a small … That is, small but true differences may exist between many of the categories we summarized into our

28. Designing a Deliberative Forum (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/delilberative-methods-design-abelson.pdf
    May 29, 2025 - 100 – 1000+ or smaller groups of 12-20 Key considerations  Ensure adequate opportunity for small-group … participation and meaningful deliberation  Establish clear goals and carefully manage transitions between small

29. Therapies for Clinically Localized Prostate Cancer: Evidence Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/prostate-cancer-therapies-summary.pdf
    September 01, 2020 - We derived a priori thresholds defining “small,” “moderate,” and “large” effect sizes for benefits and … 3 Watchful waiting may result in moderate to large increases in overall mortality and small … WW probably results in small to large increases in metastases through 15–20 years. … Metastases were infrequent, but AM probably results in a small increase compared with RP and EBR+AD. … EBR plus AD probably results in a small reduction in overall mortality and may result in a small reduction

30. Noninvasive Treatments for Low Back Pain (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
    February 01, 2016 - Effects on function were small for NSAIDs, opioids, tramadol, and duloxetine. … Effects were small to moderate in magnitude. … to no effect 2 RCTs Low Small to no effect 2 RCTs Low Spinal manipulation vs. sham Small 2 RCTs Low … MCE vs. general exercise (long term) Small, favors MCE for long term 1 SR (4 RCTs) Low Small, favors … no lumbar support, but effects were small. There was no clear effect on function.

31. Hemorrhage-Postpartum Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
    April 01, 2015 - Six small studies of fair and poor quality each addressed different drugs. … Six small studies of recombinant activated factor VIIa (rFVIIa) had mixed results. … number of studies and small sample sizes. … Six small studies of fair and poor quality addressed different pharmacologic agents. … medical management in 1 small study with high limitations.

32. Treatment Resistant Depression Surveillance FINAL (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_surveillance.pdf
    April 01, 2016 - One small Tier 1 RCT (n=131), identified by an expert found no difference in adherence when comparing … Likely Current Two very small new uncontrolled trials report positive effects of rTMS on patients … Tier 1: A small multi-site RCT (n=73) compared ECT (n=38) to APT (n=35) for treatment resistant … Tier 3: A small phase II RCT (n=60) examined individuals with MDD who had responded to ECT and … Likely Current One very small study of HFrTMS found increases in QOL scores for global, physical,

33. Evidence Summary for CER 239: Acute Treatments for Episodic Migraine (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
    December 01, 2020 - • Only a small number of studies have evaluated opioids. … • Although only studied in one or a few small trials, several other therapies available in the United … Other comparisons: • Although only studied in one or a few small trials, several other therapies may … • Although only studied in one or a few small trials, several nonpharmacological acute treatments … Limitations For many interventions, very few or a single trial were available and most were small,

34. Comparative Effectiveness of Initial Chemotherapy for Advanced Non-Small Cell Lung Cancer | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/lung-cancer-chemotherapy/abstract

35. Hunt_Panel_1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/hunt_panel_1.pdf
    January 01, 2010 - Practice Gap • Evidence-­‐based treatments can  double or even  triple success rates, but only a small … aware o Real-­‐time (cravings support) Slide  8: Make  It Easy • Microengagements o Keep content small … • How can keep content  small and fast  and create opportunities for microengagements?

36. Dp5 Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/dp5_summary.pdf
    January 01, 2009 - Claim Count No. of No. of File Type Year Category No. of Categories Mean Minimum Median Maximum Small … Cells Mean Minimum Median Maximum Small Cells DME 2006 5-digit ICD-9 11,549 1,439 1 8 2,921,847 … Category No. of Categories Beneficiary Count Claim Count Mean Minimum Median Maximum No. of Small … Cells Mean Minimum Median Maximum No. of Small Cells Inpatient 2009 3-digit ICD-9 926 14,122 … Cells Mean Minimum Median Maximum No. of Small Cells SNF 2009 5-digit ICD-9 7,889 331 1 7 455,691

37. Lung-Cancer-Nonsurgical-Therapies Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
    June 01, 2013 - Lung Cancer Executive Summary Background Non–small-cell lung cancer (NSCLC) refers to any type of … epithelial lung cancer other than small-cell lung cancer.1 The disease arises from epithelial cells … Laser Versus PDT The evidence for this comparison comprised one small RCT40 (n=31). … The role of radiation therapy in non-small cell lung cancer. … Palliative endobronchial brachytherapy for non-small cell lung cancer.

38. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_executive.pdf
    October 01, 2007 - Only one small trial of PCI vs. CABG used drug-eluting stents (Seoul-Hong). … The PCI- CABG difference in freedom from MI was small, less than 1 percent (PCI/CABG odds ratios ranged … , was compared with PCI in eight small randomized trials. … Groningen A small, single-center Dutch study of 100 patients with single-vessel proximal LAD disease … Myoprotect I A small, single-center German trial of 44 high-risk patients with left main or left main

39. Medical Therapies for Children With Autism Spectrum Disorder—An Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
    May 01, 2017 - – Omega-3 fatty acids, N-acetylcysteine, and tetrahydrobiopterin did not improve outcomes in small … In two small trials, bumetanide plus applied behavior analysis improved symptom severity more than … N-acetylcysteine had no effect on social skills outcomes in two small RCTs. … Most studies were small (median 40 total participants/ study) and addressed variable agents. … Data were inadequate in a small study of guanfacine to draw conclusions about effects on any outcomes

40. Slide 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cf_deliberativemethodswebinar_desigingdeliberativeforum.pdf
    May 29, 2025 - of 100 – 1000+ or smaller groups of 12-20 Key considerations • Ensure adequate opportunity for small-group … and meaningful deliberation • Establish clear goals and carefully manage transitions between small