-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0108_05-24-2009.pdf
January 01, 2009 - These
consensus statements have been supported by multiple small trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-206-evidence-summary-sodium-potassium.pdf
June 01, 2018 - eight RCTs); however,
a sensitivity analysis that excluded high or unclear
RoB studies resulted in a small … studies had high RoB for the
methods used to assess sodium intake, and the number
of studies was small … • Evidence from a small number of RCTs does not
support an effect of sodium reduction on the risk … The methods used to estimate sodium
intake varied across the observational studies, and only
a small … • Of the small number of studies that assessed long term
CVD outcomes, few assessed these as primary
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
July 08, 2014 - The meta-analysis by Grote et al found very small effects
of depression on birth outcomes that may be … Even if the effects of
depression on birth outcomes are small, we do not feel that an
alternative is … suggest future research should focus on the comparative risk of
congenital anomalies and although a small … In this very small study, depression was measured in two ways; the
BDI and a Likert scale. … evidence discussed here is insufficient to support conclusions
because it is based on a single very small
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rotator-cuff-tears-future_research.pdf
February 01, 2013 - The literature limitations included low study quality, disparate
treatments and outcomes, small sample … Even with 100 percent participation, the prioritization activity was limited to a small sample, and … However, a small proportion of ongoing studies focus
on the broader questions in rotator cuff treatment … RCTs with sufficient sample sizes
are able to detect small treatment effects or differences in rotator … Single-row versus double-row
arthroscopic rotator cuff repair in small- to medium-sized tears.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery_research.pdf
June 01, 2010 - Not have a diagnosis of cancer of the esophagus (ICD-9 150-150.9), stomach (ICD-9
151-151.9), small … hyperlipidemia and hypertension, although this
has been described previously.
15,16
There is a small … Gastric
bypass
43645 Laparoscopy, surgical, gastric restrictive procedure; with gastric bypass and small … Gastric
bypass
43847 Gastric restrictive procedure, with gastric bypass for morbid obesity; with small … bowel to small bowel anastomosis Other
4551
1
Isolated intestinal bypass, small bowel to segment
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_disposition-comments.pdf
May 27, 2010 - This includes the majority of the 3D RT
papers, and excludes a small minority in which 3D techniques … We agree
that all the randomized studies were small and that multivariate analyses for
confounding … to deliver higher doses to the tumor
site may in fact present a risk ..should be removed: There are small … This includes the majority of the 3D RT papers, and excludes a
small minority in which 3D techniques … We agree that all
the randomized studies were small and that multivariate analyses for confounding
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
June 01, 2013 - a systematic process that involves compiling
information on topics and issuing topic drafts to a small … One new therapy has emerged to address a very small proportion of the CF population, but
the remainder … Intervention: Ivacaftor (Kalydeco™) is a small-molecule, CF transmembrane conductance
regulator (CFTR … However, because of the small patient population and the drug’s oral administration,
ivacaftor is not … the importance of this unmet need is tempered because
CF is a rare condition and that within the small
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
April 01, 2012 - systematic process that involves compiling a profile
on topics and issuing topic profile drafts to a small … However, experts also cited the small evidence base,
lack of long-term data, serious risks associated … However, the experts cited the
small evidence base, lack of long-term data, serious adverse events … However, the experts cited the small evidence base, lack of long-term
data, serious risks associated … Ivacaftor (Kalydeco™, VX-770, Vertex
Pharmaceuticals, Inc., Cambridge, MA) is a small-molecule, cystic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_executive.pdf
June 01, 2013 - We identified three controlled trials
and two small cohort studies comparing surgery with
nonsurgical … Still, we identified only
two observational studies comparing surgical procedures
and two small cohort … Outcomes at 12 to
24 months were reported for only a small number of
patients (6.8 percent) presumably … that involves removing 70 percent of the stomach,
along with bypassing a significant proportion of small … Roux-en-Y gastric bypass (RYGB): A surgical weight-
loss procedure that involves the creation of a small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
September 28, 2015 - Also in the executive summary, we now state “In the
comparisons with active controls, the small number … If not, then small and large studies
Studies were weighted by sample size and variance. … Peer Reviewer 4 Methods For publication bias, better to call it a small study effect
with publication … effect sizes) and
our assessment that many of the studies were small
or had unfavorable outcomes. … Some nodes had very
few studies, small sample sizes, and/or wide
credibility intervals, thus we did
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - We therefore excluded small (n < 50) single-site studies
reporting the results of specific surgical … However, exploration of heterogeneity was typically
limited by the small number of studies for each … These studies examined a wide range of interventions,
but sample sizes often were small. … Other types of support surfaces
were evaluated only in small single studies. … Most studies were
small, and many were underpowered to detect significant
differences.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
July 01, 2010 - operative approach should be used for
different types of tears (e.g., partial-thickness
or full-thickness; small … treatment approach
should be used for different types of tears
(e.g., partial-thickness, full-thickness; small … The three comparative studies were
relatively small and no overall conclusions were
possible. … Operative augmentation
Porcine small intestine submucosa vs. no Low The evidence was too limited to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow_executive.pdf
January 01, 2017 - • The clinical significance of differences
in discrimination is likely to be small
and could be offset … We defined
a small difference in the AUROC a priori as a difference
of less than 0.05, moderate as … – One study found very small differences between
out-of-hospital tGCS (cutoff of ≤13) versus the … However, the difference in the AUROC on each
of these outcomes was small (<0.05). … The clinical significance of
small differences in discrimination is likely to be small,
and could be
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ehc-research-gaps-telehealth.pdf
April 01, 2023 - outcomes as compared with in-
person care; differences in clinical outcomes, when
seen, were generally small … schedules with fewer visits did not show
differences in gestational age at birth, likelihood of
being small … particularly for the
prioritized outcomes that occur infrequently (e.g.,
NICU admissions, preterm birth, and small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
April 01, 2012 - Echinacea
In one small study in 12 healthy male participants (low
CHD risk),59 post-treatment levels … Hawthorn
One small trial72 found no significant difference in an
ECG measure (PR interval, which is … Most of these studies recruited a small number of
participants and were underpowered for the outcomes … Sample sizes were generally small,
except for one study that recruited over 9,000 women.39
Vitamin … As extant literature is largely based on few small-
size efficacy studies of limited internal validity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_clinician.pdf
July 01, 2016 - standard for diagnosing celiac disease, but the
procedure is invasive and accompanied by a risk, albeit small … b This systematic review represents a review of video capsule endoscopy (VCE) for various suspected small-intestine … It is usually asymptomatic but
may cause small-bowel obstruction or require surgical removal (especially
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_consumer.pdf
January 01, 2016 - � T1: The cancer is too small to be felt during a digital rectal exam
or seen in an imaging test … The doctor then uses
an ultrasound probe to
guide the needles that
place small radioactive
seeds … difficult to urinate)**
��Trouble getting or keeping an erection
��Loss of fertility†
��Hernia††
��Small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
December 01, 2015 - full-text review because our
preliminary searches indicated that non–English-language
studies had small … sample sizes and represented a small
portion of the evidence base for any given test modality,
so … Only six small studies reported
that other pathology was found when appendicitis was
also present … risk
of bias, a relatively small number of direct comparisons
among index tests in diagnostic cohort … Many had sample sizes that were too
small to reliably detect small or moderate differences
between
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - • Comparable THC to CBD ratio oral spray is probably associated with small
improvements in pain … Comparable THC to
CBD Ratio Benefits
and Harms
Benefits: small improvements in
pain severity and … a Potential effect: SOE of low or higher; findings indicate at least a small magnitude of effect but … Magnitude of benefit was categorized into no effect or small, moderate, and large
effects. … Improvement in pain
was small to moderate with high and comparable THC to CBD ratio products.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-exe-sum.pdf
April 01, 2025 - Of eight RCTs and two comparative observational studies, only one small trial
of CBT (n=40 patients) … with supportive group treatment matched for treatment format and frequency.
5
One small … One small RCT suggested that ABFT was more
effective than usual care in reducing SI and suicidal behavior … identified only one study examining a pharmacological treatment for suicidal
youth.48, 49 Due to the small … In the context of small sample
7
size and short followup, potentially effective