-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
September 01, 2017 - We identified one small study using gabapentin (off-label)
in primary care. … A single
small trial of a lower dose of naltrexone (n=128)24 with conflicting results is unlikely to … Most studies were
small, and results were inconsistent. … New information for KQ4, KQ5 and KQ6 is limited by the small number of studies, and
heterogeneity of … Unsure
Likely current
(Small studies
found no
effect.)
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
December 01, 2022 - of Studies: Effectiveness and implementation studies
frequently employed less rigorous designs, had small … implementation across study sites
• The most frequently identified weakness after overall study design is small … rigorous study designs that do not sufficiently
address differences in the groups compared and include small
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
March 01, 2011 - Otherwise, option 1, difference
between post scores, produces a small SE. … If the sample size is small and the
study obtained the p-value using a two-sample t-test, then the … The bias associated with the use of SMD is small when the true variance is small relative to
the effect … Caution is warranted when RoM is used for small trials with large SDs and large
effect sizes. … SMDs of 0.2, 0.5, and 0.8 correspond to small, medium, and large effects.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_appendixes.pdf
June 16, 2008 - Carbon ion radiotherapy for stage I non-small
cell lung cancer. … High-dose proton beam therapy for Stage I non-small-cell
lung cancer. … Proton irradiation for non-small cell lung cancer. … Clinical evaluation of proton radiotherapy for non-
small-cell lung cancer. … Proton irradiation of small choroidal malignant
melanomas.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - The small
number of lesions in this study precludes reliable
conclusions. … In general, differences among tests were
relatively small: for example, differences in sensitivity … Comparisons among MRI-guided biopsy methods
were imprecise, reflecting the small number of available … MRI-guided biopsies were
evaluated in only six studies with small sample sizes,
leading to substantial … Because the
number of studies of women at high risk of cancer was
small, comparisons of test performance
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
January 07, 2016 - Do small changes in serum creaitnine necessarily represent changes in kidney
function (e.g. … The
disease populations differ and the number of
studies on each disease population is too
small to … Due to the small numbers, this is really a question
of noninferiority margins, and the authors did not … approach this issue in this way
because the confidence intervals are so large with such small sample … The meta-analysis included 63 randomized controlled trials which were
mostly small and open label.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - There appears to be a small difference in change in
diabetes control, renal function between ACEIs and … ARBs (favoring ACEIs),
progression of but this difference is both small and most likely not clinically … studies of LV mass/
Low (ACEI vs. function, these were dominated by poor-quality studies with
ARB); small … ACEI or in longitudinal cohort studies, and relatively small sample
ARB) sizes for ARBs, the precise
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism_research-protocol.pdf
December 09, 2009 - interventions that vary in their modality;
many lack a systematic evidence base and are instead supported by small … case series, single
cases, or small, short-term trials. … interventions.7 While controlled trials seem to be increasing,
much research is observational, generally with small … Sample sizes must be appropriate for the study question
addressed in the paper; single case reports or small … adolescents, we do not want to lose those
studies that are predominantly about children, but may include a small
-
effectivehealthcare.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
January 01, 2010 - interventions that vary in their modality;
many lack a systematic evidence base and are instead supported by small … case series, single
cases, or small, short-term trials. … interventions.7 While controlled trials seem to be increasing,
much research is observational, generally with small … Sample sizes must be appropriate for the study question
addressed in the paper; single case reports or small … adolescents, we do not want to lose those
studies that are predominantly about children, but may include a small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
September 01, 2011 - climb during that decade, it was due to medically indicated
deliveries and attempted to salvage very small … and 8709), (respectively)
and speak strongest to the lack of adverse cardiac side effects with
this small … Finally, it is unlikely
given the small numbers of deliveries at gestational ages below 28-
30 weeks … This again underscores my concern that the expressed
statistical suspicion of bias, however small, will … Peer Reviewer 3 General The figures are a bit small. Figures have been enlarged.
-
effectivehealthcare.ahrq.gov/sites/default/files/sadwin.pdf
January 01, 2011 - Slide 12
Image: Screenshot of 'small steps to BIG changes' of the My Life Check website.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - reviews found that opioids,11 several nonopioid drugs,12 and
some nonpharmacologic treatments13 have small … Publication bias (small sample size bias) will
be assessed using funnel plots when there are eight or … A small/slight effect is
defined for pain as a mean between-group difference following treatment of … Small effects using this system may be below published thresholds for clinically
meaningful effects; … For
some patients a small improvement in pain or function using a treatment with low cost or no
serious
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
March 14, 2012 - Idiopathic gastroparesis is the most
common etiology, estimated by some small studies to range between … Then pressure measurements are captured, which provide
information about the small bowel and gastric … This new modality
is a portable, small capsule that, when swallowed, records and transmits data to a … Wireless motility
capsule testing has been studied in small trials to assess gastric emptying. … The patient takes the pill after eating a standardized meal and wears a small monitor that allows
the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - earlier detection of
cancer prior to symptoms.[5] The greatest increase in incidence was noted in small … 20, 2015
2
characteristics into composite models to classify tumors preoperatively.[12-15] In small … Larger or central
tumors are more likely to be invasive, but small peripheral tumors may also be invasive … For instance, young women with small
(<2 cm) tumors have the highest likelihood of having benign tumors … Mullins, J.K., et al., Tumor complexity predicts malignant disease for small renal masses.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
February 01, 2008 - One small (N=106), older
trial indicated that, compared with EBRT, RP was
more effective in preventing … One small RCT comparing RP
alone and RP combined with neoadjuvant ADT
found no overall or disease-specific … One small trial comparing different doses
of supplemental EBRT, 20 Gy (N=83) vs. 44 Gy
(N=76), adjuvant … Preliminary
results from one small trial (N=126) comparing
125I with 103Pd brachytherapy found similar … Iridium brachytherapy Low 1 small trial with an adequate method of allocation.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-testing-machine-learning-tool-chronic-pain.pdf
November 01, 2020 - • Use of the machine learning classifier resulted in a small to moderate estimated time
savings … relevant articles but subsequently minimized irrelevant studies
at the expense of possibly missing small … Due to the small number of studies included in each
monthly update search, we tested the update searches … The estimated time savings ranged from small to moderate, totaling 2.0 to 13.2 hours when
update searches … The update searches were imbalanced (i.e., small number of included citations
relative to the number
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Based on this, we will
continue to track the intervention for additional data from two small ongoing … In small studies, ketamine administration also reduced suicidal ideation
in depressed inpatients and … In clinical trials and small studies, telemedicine facilitates
delivery of one, or a combination, of … Patients are often responsible for none or a small portion of these costs, particularly in
cases in … Off-label
prescriptions for depression pick up in small
clinics, part 2. [internet].
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
September 22, 2011 - There was a very small
change in the self-administered treatment group (67.3 vs.
69.8). … (Strength of evidence = insufficient)
• One small fair-quality RCT found greater
improvements in QOL … In addition, the relatively small trial (n=29) comparing the
effect of CBT with usual care found that … The six included RCTs were rated as primarily poor
quality, with small sample sizes (21–250). … Only two
small poor-quality studies27,28 reported data on QOL.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-executive-summ.pdf
January 01, 2023 - States (59%) and had
sample sizes in the range of 25 to 99 participants (58%), with a relatively
small … military) participants,
and had sample sizes in the range of 25 to 99 participants (53%); a
relatively small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
June 01, 2022 - We did not conduct statistical
or graphical methods for assessing for small sample effects (a potential … marker for
publication bias) due to small numbers of trials and heterogeneity in study design
methods