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effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
October 01, 2015 - – Evidence for other head-to-head comparisons of
urinary biomarkers was based on small numbers of … MMC Versus Epirubicin:
• One small trial found no difference between MMC and
epirubicin 80 mg in risk … epirubicin: Local
adverse events
Low One small trial found no difference between
MMC and epirubicin … CIs that are too
narrow when heterogeneity is present, particularly when
the number of studies is small … Other
than quantitative NMP22 and qualitative BTA, urinary
biomarkers were assessed in small numbers
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/machine-learning-quality_research.pdf
September 01, 2012 - The selected training sample represents a small percentage (17 percent) of the total search
output … Wallace BC, Small K, Brodley C. et al. Active
learning for biomedical citation screening. … LIMITATIONS: The study involved a small number of practices and
lacked a pure control group. … Although this project initially focused on a small number of
patients, it has enabled the teams to … A small number of protocols with the specific aims of reducing the length of
stay in the ED as well
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
May 27, 2014 - Because of the number of permutations of outcomes and the
relatively small number of trials, I question … , given the economic imperatives currently, it is
somewhat surprising that the evidence base is as small … It may take a small table showing the
definition (which is probably quite varied) among the studies … Font is quite
small…. … There is the very strong (though small study size) effect from the
Naylor study.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
May 08, 2013 - Regarding the quality of the studies, we agree that there were many studies of poor
quality and/or small … to low air-loss beds
compared to standard foam
mattresses” is potentially
misleading because the small … Small RCT but,
nevertheless, with very clear
findings in favour of AP over an air
filled reactive … Effect sizes were small, no studies showed an impact on complete wound healing,
the highest strength … To continually rely on a small
handful of weak and outdated
papers, plus a questionable
retrospective
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - Notably, weight change was
small to moderate, generally less than 2 kg between
baseline and final values … The effects on lipid levels varied across
medication type, but most were small to moderate
(changes of … three
comparisons were included for the outcome of
neuropathy, and these studies were limited by their
small
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
September 01, 2010 - thickness
inflammation that can occur anywhere in the gastrointestinal tract, but most often affects small … course of many years.4 The most common complications of Crohn’s include fibrotic narrowings
in the small … Surgical management of upper gastrointestinal and small bowel Crohn's
disease.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
February 01, 2012 - There was a
preponderance of small uncontrolled studies, as is often the case in the study of rare diseases … regimens was outside the scope
of the CER due to their evolving nature and difficulties in stratifying small … There was a preponderance of
small, uncontrolled studies, as is often the case in the study of rare … ability to
recruit:
Recruitment is a challenge as the
numbers of patients at any one
center is small … However,
multicenter studies would be
employed to recruit patients in a
timely manner due to the small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
November 01, 2010 - This lack of balance may be due in part to the
small size of the trial (n=23). … appropriately
randomize based on their internal methodology and report on this
difference within a small … We unequivocally agree that that even small change
can be powerful and meaningful; however, it is also … For example, Elder et al conducted a
small RCT and found no benefits. … Perhaps this
study was too small to include in the review?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
August 01, 2012 - only reported proportions of patients
in each treatment group with the outcome and a p-value), and small … The single randomized,
controlled trial had too small of a sample size and
too short of a follow up … the 2-
5-year overall
survival between
IMRT and 3DCRT
(or 2DRT) and was
inconclusive due to
very small … The single randomized, controlled
trial had too small of a sample size and too short of a
followup
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
March 01, 2015 - Small differences in effect
magnitudes among SSRIs/SNRIs, isoflavones, gabapentin,
black cohosh, and … We identified large trials examining
vitamin E, small trials of isoflavones, and observational
studies … Symptom Relief in Subgroups
A small subset of trials identified for Key Question
1 reported subgroup … The closeness of most
network and pairwise estimates shows that inconsistencies
are likely small.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
September 26, 2014 - a systematic process that involves compiling
information on topics and issuing topic drafts to a small … , 30
mL pouch where food will enter.95 The surgeon then connects the distal small intestine to this … Next, the surgeon connects the duodenum portion of the upper small intestine to a distal section of … the small intestine. … The procedure connects the ileum, the lowest part of the small
intestine, to the proximal intestine
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
August 09, 2013 - does not always differentiate malignant from
benign pancreatic lesions, and its ability to detect small … tumors or small hepatic/peritoneal
metastases is limited. … The endoscopist can take a small aspiration (FNA) of
any suspicious lesions, permitting cytologic evaluation … MRI may be helpful when characterizing small (<1 cm) hepatic
lesions, differentiating an inflammatory … Trikalinos TA, Hoaglin DC, Small KM, et al.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
June 01, 2010 - While the use of rFVIIa might have increased
over the same period, it accounted for only a very small … Introduction Patients with hemophilia with long-term inhibitors constitute a small but
significant portion … even though
the use of rFVIIa might have increased over this period, it still
accounted for a very small … Null assessments that are relatively
precise are those where the statistical estimate has small
confidence … Despite their relatively small
populations, rFVIIa use by patients with hemophilia with inhibitors or
-
effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
January 01, 2013 - A limited exception may be when the magnitude of bias is known to be small. … One limited exception may be when the magnitude of bias is known to be small.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
June 01, 2010 - Progesterone treatment for preventing preterm birth was first studied in several small trials
during … • Sample sizes must be appropriate for study question addressed in paper;
single case reports or small
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - robustness certainty surrounding these estimates given the
presence of outcome reporting bias and small … For small study bias, the Harbord test for small study effects is
considered to be superior to Eggers … findings, e.g. for
cardiovascular mortality, there are only a total of 24 events
which is a very small … ) studies
produced discrepant results (this also resulted in a
statistically significant test for small … And stent
thrombosis showed strong evidence for small study effects
using the Egger test.
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - These comparisons had no or small differences (<2 beats
per minute) between groups (Table C). … A 2011 Cochrane systematic review showed small
between-group differences in HbA1c, around 0.3 percent … some combination comparisons
were more effective than others, most between-group
differences were small … Weight gain was small to moderate in the trials in which
participants gained weight; even in the longest … While the clinical relevance of these small differences is
unclear, a change of 3 to 5 mmHg is about
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - depends on the specific
statistic used; generally, a sample size of 50 excludes studies that are too small … review because our preliminary searches indicate that non–English-
language studies are few and have small … Such criteria are often inadequate
(e.g., low power when the number of studies is small) and do not … larger) and less precise (smaller) studies will be assessed using the Egger regression-
based test for small-study
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
July 01, 2012 - In most instances,
there was small to moderate variability in effects,
even across diagnostic groups … Comment Response
Peer Reviewer 5 Executive
Summary
Page 26 [ES-18], line 38 – “Because of the small … In most instances,
there was small to moderate variability in effects,
even across diagnostic groups … prognostic factors
may be reported or even known, (3) clinically important differences may
be concealed by small
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/multinational-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - outcomes for psoriasis patients treated with systemic
agents; however, these registries typically had small … enroll as many patients as possible from a very limited global pool
of patients; given the extremely small … validation, each
translated CRF also should undergo cognitive debriefing, where it is tested on a small … These incentives may take the form of small payments (often in the form of gift cards); in
addition,