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Showing results for "small".

1241. Bladder-Cancer-Non-Muscle-Invasive Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
      October 01, 2015 - – Evidence for other head-to-head comparisons of urinary biomarkers was based on small numbers of … MMC Versus Epirubicin: • One small trial found no difference between MMC and epirubicin 80 mg in risk … epirubicin: Local adverse events Low One small trial found no difference between MMC and epirubicin … CIs that are too narrow when heterogeneity is present, particularly when the number of studies is small … Other than quantitative NMP22 and qualitative BTA, urinary biomarkers were assessed in small numbers

1242. Machine Learning Methods in Systematic Reviews: Identifying Quality Improvement Intervention Evaluations (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/machine-learning-quality_research.pdf
      September 01, 2012 - The selected training sample represents a small percentage (17 percent) of the total search output … Wallace BC, Small K, Brodley C. et al. Active learning for biomedical citation screening. … LIMITATIONS: The study involved a small number of practices and lacked a pure control group. … Although this project initially focused on a small number of patients, it has enabled the teams to … A small number of protocols with the specific aims of reducing the length of stay in the ED as well

1243. Disposition of Comments for Comparative Effectiveness Review 133 Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
      May 27, 2014 - Because of the number of permutations of outcomes and the relatively small number of trials, I question … , given the economic imperatives currently, it is somewhat surprising that the evidence base is as small … It may take a small table showing the definition (which is probably quite varied) among the studies … Font is quite small…. … There is the very strong (though small study size) effect from the Naylor study.

1244. Disposition of Comments for Pressure Ulcer Treatment Strategies: Comparative Effectiveness (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
      May 08, 2013 - Regarding the quality of the studies, we agree that there were many studies of poor quality and/or small … to low air-loss beds compared to standard foam mattresses” is potentially misleading because the small … Small RCT but, nevertheless, with very clear findings in favour of AP over an air filled reactive … Effect sizes were small, no studies showed an impact on complete wound healing, the highest strength … To continually rely on a small handful of weak and outdated papers, plus a questionable retrospective

1245. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
      March 01, 2011 - Notably, weight change was small to moderate, generally less than 2 kg between baseline and final values … The effects on lipid levels varied across medication type, but most were small to moderate (changes of … three comparisons were included for the outcome of neuropathy, and these studies were limited by their small

1246. Evidence Report on the (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
      September 01, 2010 - thickness inflammation that can occur anywhere in the gastrointestinal tract, but most often affects small … course of many years.4 The most common complications of Crohn’s include fibrotic narrowings in the small … Surgical management of upper gastrointestinal and small bowel Crohn's disease.

1247. Future Research Needs for Hematopoietic Stem-Cell Transplantation in the Pediatric Population (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
      February 01, 2012 - There was a preponderance of small uncontrolled studies, as is often the case in the study of rare diseases … regimens was outside the scope of the CER due to their evolving nature and difficulties in stratifying small … There was a preponderance of small, uncontrolled studies, as is often the case in the study of rare … ability to recruit: Recruitment is a challenge as the numbers of patients at any one center is small … However, multicenter studies would be employed to recruit patients in a timely manner due to the small

1248. Microsoft Word - Comparative_Effectiveness_Research_Review_Disposition_of_Comments_Report_Final_120710_refs_delinked1.docx (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism_disposition-comments.pdf
      November 01, 2010 - This lack of balance may be due in part to the small size of the trial (n=23). … appropriately randomize based on their internal methodology and report on this difference within a small … We unequivocally agree that that even small change can be powerful and meaningful; however, it is also … For example, Elder et al conducted a small RCT and found no benefits. … Perhaps this study was too small to include in the review?

1249. Surveillance & Identification of Triggers for Updating Systematic Reviews for the EHC Program (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
      August 01, 2012 - only reported proportions of patients in each treatment group with the outcome and a p-value), and small … The single randomized, controlled trial had too small of a sample size and too short of a follow up … the 2- 5-year overall survival between IMRT and 3DCRT (or 2DRT) and was inconclusive due to very small … The single randomized, controlled trial had too small of a sample size and too short of a followup

1250. Menopause Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
      March 01, 2015 - Small differences in effect magnitudes among SSRIs/SNRIs, isoflavones, gabapentin, black cohosh, and … We identified large trials examining vitamin E, small trials of isoflavones, and observational studies … Symptom Relief in Subgroups A small subset of trials identified for Key Question 1 reported subgroup … The closeness of most network and pairwise estimates shows that inconsistencies are likely small.

1251. Diabetes Mellitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1406.pdf
      September 26, 2014 - a systematic process that involves compiling information on topics and issuing topic drafts to a small … , 30 mL pouch where food will enter.95 The surgeon then connects the distal small intestine to this … Next, the surgeon connects the duodenum portion of the upper small intestine to a distal section of … the small intestine. … The procedure connects the ileum, the lowest part of the small intestine, to the proximal intestine

1252. Cancer-Pancreas Research-Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
      August 09, 2013 - does not always differentiate malignant from benign pancreatic lesions, and its ability to detect small … tumors or small hepatic/peritoneal metastases is limited. … The endoscopist can take a small aspiration (FNA) of any suspicious lesions, permitting cytologic evaluation … MRI may be helpful when characterizing small (<1 cm) hepatic lesions, differentiating an inflammatory … Trikalinos TA, Hoaglin DC, Small KM, et al.

1253. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
      June 01, 2010 - While the use of rFVIIa might have increased over the same period, it accounted for only a very small … Introduction Patients with hemophilia with long-term inhibitors constitute a small but significant portion … even though the use of rFVIIa might have increased over this period, it still accounted for a very small … Null assessments that are relatively precise are those where the statistical estimate has small confidence … Despite their relatively small populations, rFVIIa use by patients with hemophilia with inhibitors or

1254. Slide 1
      effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
      January 01, 2013 - A limited exception may be when the magnitude of bias is known to be small. … One limited exception may be when the magnitude of bias is known to be small.

1255. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
      June 01, 2010 - Progesterone treatment for preventing preterm birth was first studied in several small trials during … • Sample sizes must be appropriate for study question addressed in paper; single case reports or small

1256. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
      September 25, 2013 - robustness certainty surrounding these estimates given the presence of outcome reporting bias and small … For small study bias, the Harbord test for small study effects is considered to be superior to Eggers … findings, e.g. for cardiovascular mortality, there are only a total of 24 events which is a very small … ) studies produced discrepant results (this also resulted in a statistically significant test for small … And stent thrombosis showed strong evidence for small study effects using the Egger test.

1257. CER 173 Executive Summary: Diabetes Medications for Adults With Type 2 Diabetes: An Update (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
      January 01, 2015 - These comparisons had no or small differences (<2 beats per minute) between groups (Table C). … A 2011 Cochrane systematic review showed small between-group differences in HbA1c, around 0.3 percent … some combination comparisons were more effective than others, most between-group differences were small … Weight gain was small to moderate in the trials in which participants gained weight; even in the longest … While the clinical relevance of these small differences is unclear, a change of 3 to 5 mmHg is about

1258. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
      November 22, 2011 - depends on the specific statistic used; generally, a sample size of 50 excludes studies that are too small … review because our preliminary searches indicate that non–English- language studies are few and have small … Such criteria are often inadequate (e.g., low power when the number of studies is small) and do not … larger) and less precise (smaller) studies will be assessed using the Egger regression- based test for small-study

1259. Disposition of Comments Report for Comparative Effectiveness Review #68 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_disposition-comments.pdf
      July 01, 2012 - In most instances, there was small to moderate variability in effects, even across diagnostic groups … Comment Response Peer Reviewer 5 Executive Summary Page 26 [ES-18], line 38 – “Because of the small … In most instances, there was small to moderate variability in effects, even across diagnostic groups … prognostic factors may be reported or even known, (3) clinically important differences may be concealed by small

1260. Research White Paper Multinational Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/multinational-registries-guide-3rd-ed-addendum-white-paper.pdf
      February 01, 2018 - outcomes for psoriasis patients treated with systemic agents; however, these registries typically had small … enroll as many patients as possible from a very limited global pool of patients; given the extremely small … validation, each translated CRF also should undergo cognitive debriefing, where it is tested on a small … These incentives may take the form of small payments (often in the form of gift cards); in addition,