-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
December 08, 2014 - cell lung
cancer
small cell lung carcinoma'/exp OR 'carcinoma small cell'/de OR
'lung small cell … cancer':de
2 ('small-cell' OR 'small cell') NEAR/2 (lung OR bronch*) OR 'oat
cell' OR sclc
3 2 … NOT ('non-small cell':ti OR 'non-small-cell':ti OR 'non small
cell':ti OR 'nonsmall cell':ti OR nsclc … cell
lung cancer
(('small-cell' OR 'small cell') AND (lung OR bronch*)) OR 'oat cell'
OR sclc … 2 2 NOT ('non-small cell'[ti] OR 'non-small-cell'[ti] OR 'non small
cell'[ti] OR 'nonsmall cell'[ti]
-
effectivehealthcare.ahrq.gov/sites/default/files/data-points-6-maps.pdf
May 29, 2025 - Enrolled Medicare Parts A and B Fee-for-Service Population, by
Hospital Referral Region, 2006
* Small … Enrolled Medicare Parts A and B Fee-for-Service Population, by
Hospital Referral Region, 2007
* Small … Enrolled Medicare Parts A and B Fee-for-Service Population, by
Hospital Referral Region, 2008
* Small … Enrolled Medicare Parts A and B Fee-for-Service Population, by
Hospital Referral Region, 2009
* Small … Enrolled Medicare Parts A and B Fee-for-Service Population, by Hospital
Referral Region, 2006
* Small
-
effectivehealthcare.ahrq.gov/sites/default/files/noninvasive-nonpharm-pain-summary.pdf
April 01, 2020 - are small). … +
moderate
+
Psychological
Therapies: CBT
Primarily
small
++
small
++
small
++
small … +
small
+ no evidence none
+
small
++ no evidence
Manual Therapies:
Massage
small
++ … +
moderate
++ no evidence
Acupuncture small
+
none
+
none
+
small
++
none
+
small … +
Multidisciplinary
Rehabilitation
small
+
small
+
none
+
small
++
small
++
none
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
September 01, 2021 - for reducing pain and improving function in older
(Medicare-eligible) populations, but benefits are small … The magnitude of effects was
classified as small, moderate or large using previously defined criteria … Vertebroplasty was associated with a
small improvement versus sham or usual care in function at 2 to … sham or usual care
Vertebral
compression
fractures
Small†
+
Moderate‡
++
Small
++
Small … ++
Small
++
Insufficient§ Small
+++
Small
++
Small
+++
Small
++
Kyphoplasty
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-251-integrated-pain-management-evidence-summary.pdf
October 01, 2021 - • Beneficial effects were usually considered small to moderate for both program
types. … a Effect size: None, small, moderate, or large difference favoring IPMP; SOE: + = low, ++ = moderate, … ++
Small
+ No evidence No evidence
Intermediate term
(≥6 to <12 months)
None
+
None
++ … Small
++
None
+
None
+
Long term
(≥12 months)
None
+
None
++
Small
+
None
+ … a Effect size: None, small, moderate, or large difference favoring CPMP; SOE: + = low, ++ = moderate,
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-evidence-summary.pdf
March 01, 2021 - inpatient
Low-strength
evidence of a small,
but nonsignificant,
difference
3 RCTs
(n=370) 12% … inpatient
Low-strength
evidence of a small,
but nonsignificant,
difference
2 cohort
studies … membrane
sweeping
Low-strength
evidence of a small,
but nonsignificant,
difference
3 RCTs … placebo
Meconium
Aspiration
Syndromed
Low-strength
evidence of a small,
but nonsignificant, … placebo
Shoulder
dystocia
Low-strength
evidence of a small,
but nonsignificant,
difference
-
effectivehealthcare.ahrq.gov/products/lung-cancer-staging/research-protocol
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - and
small improvements in function and quality of
life (SOE: High). … Topical diclofenac showed
small improvement in pain in the short term. … degree), and cannabidiol oral spray (ranging
from a small increase to large increases). … placebo
Small
++
None
+
None
+
Oxcarbazepine vs. placebo Small
++ No evidence None
+
Pregabalin … placebo
Small
++
Small
++
None
++
QoL = quality of life; SOE = strength of evidence
Effect size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
October 01, 2021 - • Comparable THC to CBD ratio oral spray is probably associated with small
improvements in pain severity … Additionally, results that were below the threshold for a small effect were considered
to reflect “no … Definitions of effect sizes
Effect Size Definition
Small effect • MD 0.5 to 1.0 points on a 0 to 10 … a Effect size: none (i.e., no effect/no statistically significant effect), small, moderate, or large … a Effect size: none (i.e., no effect/no statistically significant effect), small, moderate, or large
-
effectivehealthcare.ahrq.gov/products/lung-cancer-staging/research
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0491-140827.pdf
February 19, 2014 - Process & Next Steps
§ The topic, Imaging for Diagnosing and Staging Lung Cancer, as it relates to small … join-the-email-list1/.
§ The topic, Imaging for Diagnosing and Staging Lung Cancer, as it relates to non-small … Population(s): Patients with suspected small cell or non-small cell lung cancer
Topic Number(s): 0410 … cell lung cancer (SCLC) and non-small cell lung
cancer (NSCLC). … Both address the
use of a range of imaging modalities to diagnose (and treat) non-small cell lung cancer
-
effectivehealthcare.ahrq.gov/sites/default/files/lung-cancer-staging_executive.pdf
April 01, 2016 - CER 174 Executive Summary: Imaging for the Pretreatment of Small Cell Lung Cancer
Comparative Effectiveness … Small cell lung cancer treatment
(PDQ) health professional version. … Pathobiology and staging of small cell
carcinoma of the lung. … Impact of [(18)F]FDG-PET
on the primary staging of small-cell lung cancer. … Imaging for the Pretreatment
Staging of Small Cell Lung Cancer.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - Additionally, results that were
below the threshold for a small effect were considered to reflect “no … Results with
a small, medium, or large effect that were not statistically significant were considered … Definitions of effect sizes
Effect Size Definition
Small effect • MD 0.5 to 1.0 points on a 0 to 10 … a Potential effect: SOE of low or higher; findings indicate at least a small magnitude of effect but … Improvement in pain was
small to moderate with high and comparable THC to CBD ratio products.
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-pain-management-grand-rounds-slides.pptx
March 01, 2022 - effect (7)
[++] Small effect (6)
[++]
High-THC – Synthetic, Oral Insufficient (1) Moderate effect ( … , moderate, or large increased risk; SOE: + = low, ++ = moderate, +++ = high.
b Findings with small or … , moderate, or large increased risk; SOE: + = low, ++ = moderate, +++ = high.
b Findings with small or … effect (7) Small effect (6)
High THC – Synthetic, Oral Insufficient (2, 1 new) Small effect (7, 1 new … Synthetic oral THC (high THC to CBD ratio) products may be associated with small improvement in pain
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-research-executive-summ.pdf
April 01, 2025 - effect
+
6 RCTs
Small effect
+
Parent-only
Long term
2 RCTs
Insufficient evidence
1 RCT … effect
+
Parent-only
Intermediate term
6 RCTs
Small effect
+
3 RCTs
Moderate effect
+ … Parent-only
Long term
3 RCTs
Small effect
+
2 RCTs
Small effect
+
Multicomponent
Posttreatment … effect
+
1 RCT
Insufficient evidence
Multicomponent
Intermediate term
6 RCTs
Small effect … +
1 RCT
Insufficient evidence
Multicomponent
Long term
6 RCTs
Small effect
+
No evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-summary.pdf
August 01, 2023 - HDMF
Pain, Overall Response
(Effect Size/SOE)a
Post-RT to
4 weeks
Small favoring MF
++
Small … favoring
HDSF
+
No difference
++
>4 weeks
to 12
weeks
No difference
++
Small favoring … EBRT IMRT Vs. 3DCRT
Pain, Overall Response
(Effect Size/SOE)a
4 weeks Small
+ No evidence
12 … weeks and 26
weeks
Small
++
No difference
+
36 weeks Moderate
+ No evidence
Pain, VAS Pain … a Effect size: No, small, moderate, or large difference favoring SF scheme; SOE: + = low, ++ = moderate
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
December 01, 2020 - Otherwise, meta-
analyses were not conducted due to small number of studies, methodological limitations … The magnitude of effects was classified as small, moderate or
large using previously defined criteria … Effect sizes were primarily small to moderate for pain, the most
commonly evaluated outcome. … Muscle relaxants might be associated with
small to moderate improvement versus benzodiazepines. … An opioid plus acetaminophen or NSAID is probably associated with a
small to moderate increase in pain
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/Evidence%20Summary_0_0.pdf
April 01, 2020 - , exercise vs. active control,
and spirituality-informed online sessions vs. wait-
list), from one small … CBT)
(CDRS): 11.1;
95% CI, 17.68
to 4.52
1 RCT
(n=63)64, 65
Imprecision
(small
sample size), … CBT)
(CGAS): 6.60;
95% CI, 3.23
to 9.97
1 RCT
(n=185)23,
34-36, 40, 62, 63
Imprecision
(small … bupropion
(based on
BDI)
5.2; 95% CI,
9.31 to 1.09
1 RCT
(n=65)68
Imprecision
(small
sample … CBT)
(CDRS): 11.1;
95% CI, 17.68
to 4.52
1 RCT
(n=63)64, 65
Imprecision
(small
sample size),
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-executive-sum.pdf
January 01, 2025 - Estimates that were below the threshold for a small effect were categorized as
“no effect.”11,12
Table … effect
Small effect • MD 0.5 to 1.0 points on a 0 to 10-point scale, 5 to 10 points on a 0 to 100- … this review; it primarily consists of polyunsaturated
fatty acids and does not contain THC, but has small … , the
SOE for these products was insufficient due to evidence being limited to single trials with
small … d Potential effect: SOE of low or higher; findings indicate at least a small magnitude of effect but
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-1.pdf
July 01, 2019 - bias into meta-analysis and
reduce precision.5
► Use standard tests (e.g., Egger test) to examine small … Pooling decision tree: Steps D and E
Steps D and E: Small number of studies
• Steps D & E: Consider … these high risk of bias situations
when pooling a small number of studies:
► Small sample sizes: Results … from small trials are less reliable even
when risk of bias is low.6
− If sample sizes are small, pooled … : Steps B and C
Slide Number 12
Publication bias, reporting bias
Slide Number 14
Steps D and E: Small