-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
March 01, 2016 - and judging whether
differing interventions are differentially influenced by such factors as fibroid size … Progestin-containing intrauterine devices;
• Medications to improve or resolve symptoms or reduce size … (e.g., age, race/ethnicity; symptoms; vascular supply to fibroids; menopausal status; or
number, size … of the patients (e.g., age, menopausal status; symptom
status) and fibroid characteristics (e.g., size … data and information specific to subgroups defined by factors such as
menopausal status or fibroid size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
February 01, 2013 - * 1
Does the comparative accuracy of NITs in women vary based on: body size, heart size,
menopausal … What are the predictors of diagnostic accuracy (e.g., age, race/ethnicity, body size,
heart size, menopausal … Does the comparative accuracy of NITs in women vary based on: body size,
heart size, menopausal status … * 1
Does the comparative accuracy of NITs in women vary based on: body size, heart size,
menopausal … RCT
--Sample size needed for outcome
--Size of pool of potential subjects
--Duration of follow-up required
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-272-genitourinary-syndrome-executive-summary.pdf
July 01, 2024 - on natural products (i.e., herbal or botanical supplements and
vitamins) and were small in sample size … hyaluronic acid; MBS=most bothersome symptom; NR=not reported; N/A=not assessed; OIS = optimal information size … did not provide adequate statistical reporting)
dDowngraded one level for imprecision (total sample size … imprecision (SD crosses no-effect threshold)
fDowngraded two levels for imprecision (total sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-259-partial-breast-irradiation-executive-summary.pdf
January 01, 2023 - Additionally, the results of subgroup analysis are limited by sample size and the risk of
false-positive … Defining an optimal radiation dose,
fractionation, and target size using contemporary techniques for … age range,
estrogen receptor (ER) positive status, grade 1-2, no lymph node involvement, and tumor
size … minority of patients who participated, for example age <50 years,
invasive lobular carcinoma, tumor size
-
effectivehealthcare.ahrq.gov/sites/default/files/prostate-cancer-therapies-summary.pdf
September 01, 2020 - ‡The node size reflects the sample size. … • Varying thresholds to define effect size estimates may alter certainty of evidence and
clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
September 02, 2016 - This spreadsheet will capture basic intervention, outcome,
study design, sample size, and whether results … to include data on study design,
intervention type and duration, population, outcomes, and sample size … We quantify such impact as a potential increase
in total study population sample size (>20%), a change … Estimating effect size under publication bias: small sample
properties and robustness of a random effects … the scope of the review to a manageable size without
compromising its validity.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
August 01, 2016 - Furthermore, some questionnaires
do not include portion size, so further estimation or
extrapolation … of potentially
eligible studies (more than 400), we applied
arbitrary thresholds based on sample size … For MI, the strength of evidence was rated
low primarily because the summary effect size estimate
was … Meta-analysis, however, found a
nonsignificant effect size (HR=0.88; 95% CI 0.77 to 1.02),
with no … Meta-analysis
found a nonsignificant effect size (HR=0.92; 95% CI 0.82
to 1.02), with no significant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
July 01, 2009 - single quantitative estimate is desired, the strength of evidence may be
insufficient if an effect size … If a meta-analysis was performed, this will be the
confidence interval around the summary effect size … This additional domain should be considered if
the effect size is particularly large. … Use one of two levels:
• Strong: Large effect size that is unlikely to
have occurred in the absence … of a true effect
of the intervention
• Weak: Small enough effect size that it could
have occurred
-
effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
January 01, 2013 - context of decisionmaking, whether the central issue is harms or benefits, and the relative effect or size … If a meta-analysis was performed, this will be the confidence interval around the summary effect size … Weak: small enough effect size that it could have occurred solely as a result of bias from confounding … Domains: Strength of Association Scores
This additional domain should be considered when the effect size … single quantitative estimate is desired, the strength of evidence may be insufficient if an effect size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
November 01, 2009 - Study design and size
3.d. Comparator used in comparative studies.
3.e. … proportional to the
logarithm of the
total sample size. … proportional to the
logarithm of the total
sample size. … proportional to the
logarithm of the total
sample size. … Study design and size
3.d. Comparators
RCTs
3.e. Length of followup
3.f.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
March 01, 2025 - healthy individuals on balanced diets.14, 15
Systematic Review on Risk of Type 2 Diabetes, Growth, Size … between dietary digestible carbohydrate intake and the incidence of T2D and
the effect on growth, size … Review of the Effect of Dietary Digestible
Carbohydrate Intake on Risk of Type 2 Diabetes, Growth,
Size … Growth, Size, and Body Composition
Seven studies with 85,827 participants reported the association between … Review of the Effect of Dietary Digestible Carbohydrate Intake on Risk of Type 2 Diabetes, Growth, Size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
December 14, 2010 - Types of bariatric surgery include laparoscopic
adjustable gastric banding (LAGB), which reduces the size … Minimum sample size of
the study is two (i.e., individual case report will not be reviewed). … For each intervention within a trial, the sample
size, mean outcome, and standard deviation will be … If all studies within a subgroup use the same scale, then the effect
size does not need to be standardized … analyses are scored so that more severely symptomatic
persons have higher scores, a negative effect size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
February 01, 2012 - following criteria:
• Advantages of the study design for producing a valid result
• Resource use, size … Resource Use,
Size and
Duration
Likely to require substantial
resources to recruit and treat the … Resource Use,
Size and Duration
Likely to require substantial
resources to recruit and
follow the … Resource Use,
Size and
Duration
Likely to require
substantial
resources to recruit
and follow … List of recently published studies
Research Gap Study Study Objective Research
Design
Sample Size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
August 01, 2012 - in statistical significance (from nonsignificant to significant)
B2 A change in relative effect size … In addition, the study was not published in a pivotal journal, and the sample size
was not larger than … and
Article ID /
Cohort/First
Author/Year
Participants
(age, sex,
condition)/
Sample size … Article ID /
Cohort/First
Author/Year
Participants
(age, sex,
condition)/
Sample size
Inclusion … but
Article ID /
Cohort/First
Author/Year
Participants
(age, sex,
condition)/
Sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
January 01, 2012 - 27 RCTs examined (22 percent) reported that they had used the findings of previous RCTs
in sample size … Several publications have proposed methods which can be used to simulate sample size
calculations and … Does the proposed study have adequate sample size and power? … Insufficient data: too few primary studies, or studies that are too small (sample size inadequate or … Evidence-based sample size calculations
based upon updated meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-mri-utilization_research.pdf
August 01, 2012 - We present results for
the comedo subtype where there is adequate sample size. … Rural refers to counties with
fewer than 2,500 people.15
Tumor size: We defined tumor size using the … Increasing size and higher grade are
related to higher rates of MRI use for
women with DCIS but not … 69 396 19.2 1,641 27.5
70-74 386 18.7 1,507 22.4
75-79 295 15.9 1,331 16.5
80+ 294 7.5 1,753 9.4
Size … In general, women with higher risk DCIS
(larger tumor size, higher grade disease, or
ER-negative tumors
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
March 01, 2018 - Comparison of the sample size, primary outcome, and withdrawals due to adverse
events reported in the … What were the differences, if any, in pre-specified outcome measures, statistical
plan and size of the … Two reviewers compared the planned sample size, the primary outcome, and the analysis
plan specified … Sample
Size
Followup
Published
literature only
Karmakar, 201435 Not found NA NA NA 28 6 weeks … Sample
Size
Followup
Published
literature
only
Thienel,
200441a
Not found NA NA NA 1269
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol-2021_0.pdf
January 01, 2021 - are screened and determined to meet inclusion criteria, study design, year, setting,
country, sample size … Characteristics
of included studies, such as number of publications by year, study sample size, proportion … Results for primary PTSD outcome (measure score and within-group effect size)
h. … Between-group effect size for primary PTSD outcome
i.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd4-final-protocol.pdf
October 01, 2022 - are screened and determined to meet inclusion criteria, study design, year, setting,
country, sample size … Characteristics of
included studies, such as number of publications by year, study sample size, proportion … Results for primary PTSD outcome (measure score and within-group effect size)
h. … Between-group effect size for primary PTSD outcome
i.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
June 01, 2012 - What are the predictors of diagnostic accuracy
(e.g., age, race/ethnicity, body size, heart size,
menopausal … , heart
size, menopausal status, functional status, stress
modality
Outcomes of women not reported … Second, the sample size and low representation
of women in most of the comparator studies may affect … Studies of sufficient sample size and representation
of women. … The Accuracy of
the Electrocardiogram during Exercise Stress Test Based on Heart
Size.