-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
January 01, 2009 - Means (Standard Deviations or Standard Errors; please specify)
rhGH group Control group
Sample size … Gallstones: Concentrated deposits of bile that can vary in size and usually form in the
gallbladder … Each study’s mean, standard deviation,
and sample size is taken into account to determine its level … For example, a study with a large sample size will have a greater impact on the
composite endpoint … than a similar study with a small sample size.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-radiation_executive.pdf
November 01, 2009 - Current clinical evidence on charged particle radiotherapy
Notes: Each circle represents a study, with size … Primary outcomes were explicitly stated in
only three trials, which also reported a priori sample
size … All trials enrolled a relatively
small sample size, ranging from 15 to 393 patients, and
studied different
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-protocol.pdf
April 08, 2024 - section, and post-partum
weight retention.18-20 Risks to the developing fetus include larger birth size … including digestible
carbohydrate intake, among infants and young children and its impact on growth, size … Outcome KQ1:
Newborn size and body
composition
• Birth weight, weight-
for-age and percentile … This may be
based on sample size sufficiency and number of events. … When quantitative
synthesis is not possible, sample size and assessment of variance within individual
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pelvic-pain_research-protocol.pdf
February 16, 2011 - • Loss to followup: varies by study; to maximize acceptable sample size, we will assume
0 percent … • Statistic: use the two-tailed z-test and the t-test for sample size. … • Sample size: for an RCT with 2 groups, with 100 percent meeting the diagnostic criteria
for CPP … size of 128 would be the smallest acceptable … • Null hypothesis of effect size of 30 percent: need 176 subjects per group; a total
sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - It is based on the potential for random error evaluated through the sufficiency of
sample size and, … EPCs can evaluate sufficiency of
sample size relative to the optimal information size (OIS). … For a given effect size (such as an OR, a
RR, or a weighted mean difference), the optimal number of … patients derives from standard
sample size calculations for a single, sufficiently powered trial. … This additional domain should be considered when the
effect size is particularly large.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
February 25, 2014 - = 0.30) the sample size per
E + C Group. … The justification for
this unacceptable sample size criteria in the Report makes
no sense. … Although it is commonly used, a minimum sample size
of 50 has no intrinsic value as a cutoff. … Rather the
decision about sample size should be based on the
purpose of the review and the methods … Methodology
guidance for EPC reviews does not stipulate a
minimum sample size for inclusion of RCTs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - The
sample size of the studies ranged from 45 15 to 2739 7. … CG: Effect size= 0.91; 95% CI= 0.56, 5.80; p<0.0001
• PFMT IT vs. … CG:
Effect size= 0.91; 95% CI=
0.56, 5.80; p<0.0001
PFMT IT vs. … a relative change in effect size of at least
50%. … CG:
Effect size= 0.91; 95% CI= 0.56, 5.80; p<0.0001
IT vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - If a meta-analysis was performed, this will be the confidence interval around the summary effect size … Two scores are possible for strength of association:
Strong: large effect size that is unlikely to have … Weak: small enough effect size that it could have occurred solely as a result of bias from confounding … Domains: Strength of Association Scores
This additional domain should be considered when the effect size … single quantitative estimate is desired, the strength of evidence may be insufficient if an effect size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-jaw-rapid-response.pdf
May 01, 2025 - country, funding source
• Study design: study design, study population eligibility criteria, sample size … for one
study in Germany,40 all included cohort studies were conducted in Asia.38,39,41–44 Sample size … tooth extractions on MRONJ occurrence
Author
Year
Country
RoB/Quality
Study Design
Sample Size … Medication
Confounder
Adjustment
Outcomes
Assessed
Treatment or Control
Group (Sample Size … Medication
Confounder
Adjustment
Outcomes
Assessed
Treatment or Control
Group (Sample Size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
October 01, 2010 - on thorough investigations of
clinical and methodological diversity as well as variation in effect size … to identify variation among effects estimates, but
their performance is influenced by number and size … from the analysis as they do not
provide information on the direction and magnitude of the effect size … on thorough investigations of clinical and
methodological diversity as well as variation in effect size … Distribution theory for Glass‘s
estimator of effect size and related
estimators.
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
October 01, 2010 - on thorough investigations of
clinical and methodological diversity as well as variation in effect size … to identify variation among effects estimates, but
their performance is influenced by number and size … from the analysis as they do not
provide information on the direction and magnitude of the effect size … on thorough investigations of clinical and
methodological diversity as well as variation in effect size … Distribution theory for Glass‘s
estimator of effect size and related
estimators.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/selecting-evidence.ppt
January 01, 2010 - be attributed to factors other than the intervention under review
Consistency
Extent to which effect size … Consistency is the extent to which the effect size and direction vary within and across studies. … Precision
Includes sample size, number of studies, and heterogeneity of effect sizes
Reporting bias
Extent … (II)
Precision is the degree of certainty surrounding a result and is determined by sample size, number … These criteria may include minimum duration of followup, minimum sample size, a defined threshold for
-
effectivehealthcare.ahrq.gov/sites/default/files/selecting-evidence.ppt
January 01, 2010 - be attributed to factors other than the intervention under review
Consistency
Extent to which effect size … Consistency is the extent to which the effect size and direction vary within and across studies. … Precision
Includes sample size, number of studies, and heterogeneity of effect sizes
Reporting bias
Extent … (II)
Precision is the degree of certainty surrounding a result and is determined by sample size, number … These criteria may include minimum duration of followup, minimum sample size, a defined threshold for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
April 01, 2013 - Again, blinding and sample size are key considerations. … This should be considered when calculating sample size. … Resource use, size
and duration
Resource requirements are high because a large sample size and long-term … Again, blinding and sample size are key considerations. … This should be considered when calculating sample size.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - are screened and determined to meet inclusion criteria, study design, year, setting,
country, sample size … Characteristics of included
studies, such as number of publications by year, study sample size, proportion … Results for primary PTSD outcome (measure score and within-group effect size)
h. … Between-group effect size for primary PTSD outcome
i.
-
effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
February 01, 2016 - size as a categorical variable
and in studies evaluating size as a continuous variable
(effect size … dNonrandomized studies must have a minimum sample size of 500 participants.
Table A. … Studies
Strength of Evidence
Finding
Tumor Size 12 Moderate
Increasing tumor size consistently is … The effect size varied by inclusion
criteria and other variables (i.e. age, tumor size). … Metastatic renal cell
carcinoma risk according to tumor size. J Urol 2009; 182(1):41-5.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
July 01, 2010 - enrolled <500 subjects will be excluded,
since numerous RCTs already exist within this smaller sample size … Observational studies will be assessed for sample size,
participant selection method, exposure measurement … when a meta-analysis is performed, we will
evaluate the confidence interval around the summary effect size … duration with
clinically relevant treatment modalities, assessed adverse events, had an adequate
sample size … Rheolytic thrombectomy with percutaneous coronary
intervention for infarct size reduction in acute myocardial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-disposition.pdf
May 26, 2017 - TEP Reviewer
#4
Methods Almost all of the studies reviewed are noted to have "small" sample
size, … Similarly, what
is the justification for using cut-offs of 10 and 20 for sample size
(understanding … Moreover, most studies noted as a
limitation their small sample size. … We selected a minimum sample size of 10 for RCTs
because we felt that the typically greater controls … for
bias and rigor helped to mitigate limitations of a
smaller sample size.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
January 01, 2023 - determined to meet inclusion criteria, we will abstract study
design, year, setting, country, sample size … Within-group results: mean scores, score difference, within-group effect size(s), calculated within- … group standardized effect size (Cohen’s d analog)
9. … effect size (Hedges’ g)
PTSD Dichotomous Outcomes
1. … Between-group results: between-group effect size for diagnostic change and/or clinically
meaningful
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting-future_research.pdf
January 01, 2014 - Intervention There is a lack of IVUS trial data on the influence of operator’s choice of balloon
size … Intervention There is a lack of IVUS trial data on the influence of operator’s choice of balloon
size … The feasibility of such studies, generally, does not depend on the desired sample size. … Resource Use, Size, and Duration
An RCT, especially one with a long duration and large sample size, … Resource Use, Size, and Duration
An RCT, especially one with a long duration and large sample size,