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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
    January 01, 2013 - planned to use single group studies, selection criteria for single group studies (minimum sample size … However, this interpretation is limited by the small sample size. F Figure 2. … the absence of the intervention of interest are believed to be well known, and the expected effect size … randomized two arm trial designs (though the two arm studies required a 2–4 fold increased sample size … the expected outcomes in the absence of the intervention are well-known, and the expected effect size
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment_research-protocol.pdf
    December 20, 2011 - In addition, we will include nonrandomized controlled trials of any sample size, prospective cohort … studies with an eligible comparison group with a sample size of at least 500, and case-control studies … with a sample size of at least 500. … We will not include observational studies with a sample size of less than 500 or for other KQs due … For KQ 6, we have chosen a sample size cutoff Source: www.effectivehealthcare.ahrq.gov Published
  3. effectivehealthcare.ahrq.gov/sites/default/files/rfviia.pptx
    May 01, 2010 - productID=450 Strength of evidence available from existing studies was compromised by: Small study size … The strength of evidence available from existing studies was thereby compromised by small study size, … rFVIIa indication using circle charts, with the area of each circle approximating the total sample size … Hemorrhage TE Events/Total Patients (%) rFVIIa Usual Care Risk Difference Summary Effect Size … Off-Label Use of rFVIIa TE Events/Total Patients (%) rFVIIa Usual Care Risk Difference Summary Effect Size
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rfviia.pptx
    May 01, 2010 - productID=450 Strength of evidence available from existing studies was compromised by: Small study size … The strength of evidence available from existing studies was thereby compromised by small study size, … rFVIIa indication using circle charts, with the area of each circle approximating the total sample size … Hemorrhage TE Events/Total Patients (%) rFVIIa Usual Care Risk Difference Summary Effect Size … Off-Label Use of rFVIIa TE Events/Total Patients (%) rFVIIa Usual Care Risk Difference Summary Effect Size
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-results-search-strategies-developed-with-without-text-mining-tools.pdf
    March 01, 2021 - Across all reviews, UP searches seemed to perform better than TMT, but because of the small sample size … usual practice (UP) search strategy development in six out of seven reports, but the small sample size … TMTs searches appear less sensitive than UP searches in all but one project, but the small sample size … Again, the small sample size precludes significance • TMTs neither affected search evaluation time … Because of the small sample size, the analysis was limited to descriptive measures, including means,
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_surveillance.pdf
    May 01, 2013 - in statistical significance (from nonsignificant to significant) B2 A change in relative effect size … Evidence Table Author, year Study design Comparison Sample size Results Serruys, 200912 (SYNTAX
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
    December 09, 2009 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: December 9, 2009 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Non-Pharmacologic Interventions for Treatment-resistant Depression i…
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
    May 01, 2016 - Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence Focus of This Summary This is a summary of a systematic review evaluating the evidence regarding the effectiveness, comparative effectiv…
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
    September 01, 2014 - ) multiplanar reconstruction images within a single breath-hold, enabling determination of tumor size … What is the staging accuracy of each imaging technique (for tumor size, lymph node status, vessel involvement … What is the staging accuracy of each imaging technique (for tumor size, lymph node status, vessel involvement … • MDCT and PET/CT use radiation and therefore can cause cancer, but the size of the risk is not possible … However, the size of the risk is not possible to estimate, specifically when used for diagnosis and
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
    April 20, 2015 - in the range of 0.55 to 0.65.[3, 16- 18] The best predictors of malignancy are male sex and tumor size … magnetic resonance imaging *Composite models need to adjust for imaging characteristics (i.e. tumor size … between event rates are between 5-10%, substantial differences between the N of two arms, or when effect size … Thompson, R.H., et al., Metastatic renal cell carcinoma risk according to tumor size. … any treated mass, any new or visually enlarging neoplasm, new nodularity, failure of regression in size
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-healthcare-community-amended-protocol.pdf
    July 02, 2020 - Data extracted will include author, year, country, study design, study dates, sample size, intervention
  12. effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
    November 01, 2020 - Interventions for Breathlessness in Patients With Advanced Cancer: Evidence Summary Comparative Effectiveness Review Number 232 Interventions for Breathlessness in Patients With Advanced Cancer Evidence Summary Main Points For patients with advanced cancer: • Airflow interventions (fans) were …
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
    December 11, 2012 - Thank you Peer Reviewer #5 Methods page 16, Key Points bullet 3: The emphasis on reporting sizeSize and number of tumors is not relevant for stratifying embolotherapy patients; instead, % tumor … heterogeneity in the studies that were evaluated re: appropriate patient population (i.e., number and size … number and size of metastases, performance status) and variations in the delivery of the interventions
  14. Slide 1 (ppt file)

    effectivehealthcare.ahrq.gov/sites/default/files/marketing_evidence_evans.ppt
    September 13, 2006 - Slide 1 Marketing “evidence” to healthcare consumers: Applying social marketing to evidence about the harms and benefits of pharmaceuticals Presented by W. Douglas Evans, Ph.D. Lauren McCormack, Ph.D., M.S.P.H Presented at Agency for Healthcare Research and Quality Conference: Communicating Harms and Benefits of …
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
    April 10, 2020 - non- pharmacological interventions was based on single (as opposed to pooled) RCTs with small sample size … include the study reference number (superscript reference number in the "study design and sample size … It emphasizes the adequacy of the sample size to rule out spurious associations and results that are
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
    July 01, 2009 - expanding its technical capabilities to complete the analyses of phase 2 as well as scale up the size … affect small populations (for which no single care delivery system would have a sufficient sample size … affect small populations (for which no single care delivery system would have a sufficient sample size … the following: GENERAL  The diabetic cohort from the Ingenix Impact Database is sufficient in size … Blueprint for the Future DARTNet has received a contract from AHRQ to expand its size, to conduct
  17. Han (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/han.pdf
    December 26, 2012 - Inconsistency of results  Indirectness of evidence  Imprecision of results  Publication  bias o Effect size
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
    December 20, 2011 - include study characteristics (e.g., first author, country of research origin, study design and sample size … In the context of intervention studies, this is the degree of spread of the summary effect size. … Precision (refers to the width of confidence intervals for diagnostic accuracy outcomes, and the effect size … for treatment monitoring; this domain is related to study sample size) 5) Other key domains (publication
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
    August 01, 2012 - limitations in study design, including selection/ spectrum bias as well as (in one study) small sample size … Studies should have an a priori calculation of the sample size needed to determine the desired precision
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
    October 18, 2010 - Randomization sequence generation x Allocation concealment4 x Adequate sample size … Assessment of Loss to Followup: Since the reported sample size could represent either the total number

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