-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
January 01, 2013 - planned to
use single group studies, selection criteria for single group studies (minimum sample size … However, this interpretation is limited by the small sample size.
F
Figure 2. … the absence of the intervention of interest are believed
to be well known, and the expected effect size … randomized two arm trial
designs (though the two arm studies required a 2–4 fold increased sample size … the expected outcomes in the absence of the intervention
are well-known, and the expected effect size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment_research-protocol.pdf
December 20, 2011 - In addition, we will include nonrandomized
controlled trials of any sample size, prospective cohort … studies with an eligible comparison group with a sample
size of at least 500, and case-control studies … with a
sample size of at least 500. … We will not include
observational studies with a sample size of less than 500
or for other KQs due … For KQ 6, we have chosen a sample size cutoff
Source: www.effectivehealthcare.ahrq.gov
Published
-
effectivehealthcare.ahrq.gov/sites/default/files/rfviia.pptx
May 01, 2010 - productID=450
Strength of evidence available from existing studies was compromised by:
Small study size … The strength of evidence available from existing studies was thereby compromised by small study size, … rFVIIa indication using circle charts, with the area of each circle approximating the total sample size … Hemorrhage TE Events/Total Patients (%)
rFVIIa Usual Care Risk Difference
Summary Effect Size … Off-Label Use of rFVIIa TE Events/Total Patients
(%)
rFVIIa Usual Care Risk Difference
Summary Effect Size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rfviia.pptx
May 01, 2010 - productID=450
Strength of evidence available from existing studies was compromised by:
Small study size … The strength of evidence available from existing studies was thereby compromised by small study size, … rFVIIa indication using circle charts, with the area of each circle approximating the total sample size … Hemorrhage TE Events/Total Patients (%)
rFVIIa Usual Care Risk Difference
Summary Effect Size … Off-Label Use of rFVIIa TE Events/Total Patients
(%)
rFVIIa Usual Care Risk Difference
Summary Effect Size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-results-search-strategies-developed-with-without-text-mining-tools.pdf
March 01, 2021 - Across all reviews, UP searches seemed to perform better than TMT, but because of the
small sample size … usual practice (UP) search strategy development in six out of seven reports,
but the small sample size … TMTs searches appear less sensitive than UP searches in all but one project, but the small
sample size … Again, the small sample size precludes
significance
• TMTs neither affected search evaluation time … Because of the small sample size, the analysis
was limited to descriptive measures, including means,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_surveillance.pdf
May 01, 2013 - in statistical significance (from nonsignificant to significant)
B2 A change in relative effect size … Evidence Table
Author, year Study design Comparison Sample size Results
Serruys, 200912
(SYNTAX
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/treatment-resistant-depression_research-protocol.pdf
December 09, 2009 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov
Published Online: December 9, 2009
1
Evidence-based Practice Center Systematic Review Protocol
Project Title: Non-Pharmacologic Interventions for Treatment-resistant
Depression i…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
May 01, 2016 - Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence
Management and Outcomes of Binge-Eating Disorder
in Adults: Current State of the Evidence
Focus of This Summary
This is a summary of a systematic review evaluating the evidence regarding the effectiveness, comparative effectiv…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
September 01, 2014 - ) multiplanar
reconstruction images within a single breath-hold, enabling
determination of tumor size … What is the staging accuracy of each imaging
technique (for tumor size, lymph node status,
vessel involvement … What is the staging accuracy of each imaging
technique (for tumor size, lymph node status,
vessel involvement … • MDCT and PET/CT use radiation and therefore can
cause cancer, but the size of the risk is not possible … However, the size of the risk is not possible to
estimate, specifically when used for diagnosis and
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_research-protocol.pdf
April 20, 2015 - in the range of 0.55 to 0.65.[3, 16-
18] The best predictors of malignancy are male sex and tumor size … magnetic
resonance imaging
*Composite models need to adjust for
imaging characteristics (i.e. tumor size … between event rates are between 5-10%, substantial differences
between the N of two arms, or when effect size … Thompson, R.H., et al., Metastatic renal cell carcinoma risk according to tumor size. … any
treated mass, any new or visually enlarging neoplasm, new nodularity, failure of regression in
size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-prevention-covid-healthcare-community-amended-protocol.pdf
July 02, 2020 - Data extracted will include author,
year, country, study design, study dates, sample size, intervention
-
effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
November 01, 2020 - Interventions for Breathlessness in Patients With Advanced Cancer: Evidence Summary
Comparative Effectiveness Review
Number 232
Interventions for Breathlessness in
Patients With Advanced Cancer
Evidence Summary
Main Points
For patients with advanced cancer:
• Airflow interventions (fans) were …
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-liver-metastases-therapies_disposition-comments.pdf
December 11, 2012 - Thank you
Peer Reviewer #5
Methods page 16, Key Points bullet 3:
The emphasis on reporting size … Size and number of
tumors is not relevant for stratifying embolotherapy patients; instead, %
tumor … heterogeneity in the studies that were evaluated re:
appropriate patient population (i.e., number and size … number and size of metastases, performance
status) and variations in the delivery of the
interventions
-
effectivehealthcare.ahrq.gov/sites/default/files/marketing_evidence_evans.ppt
September 13, 2006 - Slide 1
Marketing “evidence” to healthcare consumers: Applying social marketing to evidence about the harms and benefits of pharmaceuticals
Presented by
W. Douglas Evans, Ph.D.
Lauren McCormack, Ph.D., M.S.P.H
Presented at
Agency for Healthcare Research and Quality Conference:
Communicating Harms and Benefits of
…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
April 10, 2020 - non-
pharmacological interventions was based on single (as opposed to
pooled) RCTs with small sample size … include the study reference
number (superscript reference number in the "study design and sample
size … It emphasizes the adequacy of
the sample size to rule out spurious
associations and results that are
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-ambulatory-therapeutics_research.pdf
July 01, 2009 - expanding its technical capabilities to complete the
analyses of phase 2 as well as scale up the size … affect small populations (for which no
single care delivery system would have a sufficient sample size … affect small populations (for which no single care delivery system
would have a sufficient sample size … the following:
GENERAL
The diabetic cohort from the Ingenix Impact Database is sufficient in size … Blueprint for the Future
DARTNet has received a contract from AHRQ to expand its size, to conduct
-
effectivehealthcare.ahrq.gov/sites/default/files/han.pdf
December 26, 2012 - Inconsistency of results
Indirectness of evidence
Imprecision of results
Publication
bias
o Effect size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-natriuretic-peptide_research-protocol.pdf
December 20, 2011 - include study characteristics (e.g., first author,
country of research origin, study design and sample size … In the context of intervention studies, this is the
degree of spread of the summary effect size. … Precision (refers to the width of confidence intervals for diagnostic
accuracy outcomes, and the effect size … for treatment monitoring; this
domain is related to study sample size)
5) Other key domains (publication
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
August 01, 2012 - limitations in study design, including selection/
spectrum bias as well as (in one study) small sample
size … Studies should have an
a priori calculation of the sample size needed to determine
the desired precision
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - Randomization sequence generation
x
Allocation concealment4
x
Adequate sample size … Assessment of Loss to Followup:
Since the reported sample size could represent either the total number