-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
January 01, 2011 - The size of prospective single-arm studies ranged from
2 to 164 patients, and retrospective studies ranged
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
January 01, 2009 - duration and clinically relevant treatment modalities
Assess for adverse events
Have an adequate sample size … and clinically relevant treatment modalities
Assess for adverse events
Have an adequate sample size … comparators, whether they reflect best alternative therapy, and how this may impact treatment effect size … describe each, whether they reflect the best alternative therapy, and how this may impact treatment effect size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-nonpharmacologic-treatment_research-protocol.pdf
October 04, 2016 - strength of association, and the
possibility that all plausible confounders would increase the effect size … surrounding an effect estimate with respect to a
given outcome, based on the sufficiency of sample size … Small sample size may be an
important limitation in many studies, and addressing this through meta-analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disposition-of-comments-cer-192-anxiety-in-children.pdf
August 31, 2017 - analysis but we did
evaluate them and accounted for
them, 3) we did not have restrictions
on study size … We disagree with
reviewer that we have an “open
door” for study inclusion based on
size. … This is a common approach of
evidence synthesis and restricting
studies based on size is a mistake … funded
or small studies), we believe that the
issue is not about who funded the
study or the sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_surveillance.pdf
January 01, 2013 - in statistical significance (from nonsignificant to significant)
B2 A change in relative effect size … One study assessed the effect of optic disc
size on the diagnostic accuracy of RTVue
spectral domain … The range of sample size was 25
to 174 glaucomatous eyes and 15 to
164 healthy eyes. … Effect of disease severity and optic disc size
on diagnostic accuracy of RTVue spectral
domain optical … The range of sample size was 25 to 174
glaucomatous eyes and 15 to 164 healthy eyes.
-
effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_international_king.ppt
January 01, 2005 - What do we know about how evidence of harm and benefit is communicated in other countries?
What do we know about how evidence of harm and benefit is communicated in other countries?
Valerie King MD, MPH and David Hickam MD, MPH
John M. Eisenberg Clinical Decisions and Communications Science Center
Oregon Health &…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
February 01, 2013 - If PCI is prescribed,
the particulars of how to stent the
lesion (stent size, length, material, and … cardiac events [MACE], freedom from angina, quality
of life, and quality-adjusted survival)
Sample Size … and Study Design
We did not specify a minimum sample-size threshold
or a minimum duration of followup … We considered evidence to be
sparse if only one study of a small sample size addressed
the analysis … Of the 32 eligible studies that looked at optimizing stent
placement (i.e., stent size and dilation)
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_surveillance.pdf
January 30, 2013 - However, given the small number of
events and limited sample size
(n=42), the RCT was underpowered … Or 2) a trial not published in the above top 5 journals but have a sample size of at least triple the … size of
the previous largest trial in the original CER.
… Change in effect size of at least 50% (B2)
Refers to a situation in which the new result indicates … a relative change in effect size of at least
50%.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_surveillance.pdf
January 30, 2013 - However, given the small number of
events and limited sample size
(n=42), the RCT was underpowered … Or 2) a trial not published in the above top 5 journals but have a sample size of at least triple the … size of
the previous largest trial in the original CER.
… Change in effect size of at least 50% (B2)
Refers to a situation in which the new result indicates … a relative change in effect size of at least
50%.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/deliberative-methods_presentation-2011.pdf
January 01, 2011 - relevant
Community Forum Community Forum Community Forum
12
Length, duration
Group size
-
effectivehealthcare.ahrq.gov/sites/default/files/prostatic-hyperplasia-medications_disposition-comments.pdf
May 26, 2016 - Prostate size has not been shown to correlate well with BPH-
related LUTS (small prostates with BPH can … the sentence in the
methods section: “Inclusion criteria did not
restrict trials by minimal sample size … TEP Reviewer
#4
Methods Similarly, the methods should indicate whether there was a minimal sample size … added a sentence to
methods section: “Inclusion criteria did not
restrict trials by minimal sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/dementia-agitation-aggression_executive.pdf
March 01, 2016 - We
assessed the contextual and methodological heterogeneity
and variation in effect size to determine … direct link between intervention and
outcome); (3) consistency (similarity of effect direction
and size … However,
because the effect size was unlikely to be clinically
meaningful, the statistical difference … Sample
size calculations should also take into consideration
that individuals with dementia may change … These facilities vary greatly in size, environments, and
staffing models.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-232-breathlessness-cancer-comments.pdf
November 19, 2020 - intervention nature,
duration and intensity, and methodologic rigour
(primary outcomes,
blinding, sample size … Given the 3 studies with substantial
sample size, and our prespecified criteria, we have kept
the conclusion … opioids -
given the large number of studies, most of which are
consistent, and very small effect size … meet the inclusion criteria
but is noted in the discussion; as noted below given the
small sample size … Also, why cut studies off at a size of 10 subjects?
-
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
May 14, 2019 - EHC Technical Brief 32: Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder
Technical Brief Disposition of Comments Report
Research Review Title: Pharmacologic and Nonpharmacologic Treatments for
Posttraumatic Stress Disorder: Groundwork for a Publicly Available Repository of
…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
September 03, 2019 - Peer Reviewer
#1
Results Evidence Summary > Results: Consider mentioning total
sample size between … We have opted not to include the effect sizes in the
summary tables because the effect size for some
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
September 01, 2013 - Background context for recommendation R5.2 (“Given R5.1, regress the effect size di
versus its precision1 … hypothetical recommendation within the background context in Table 6:
R5: Use a regression of effect size … and s 2
i its sampling variance;
and a testable statement:
R5.2 Given R5.1, regress the effect size … the likelihood of publication bias based on funnel plot asymmetry
Use a regression test of effect size … The
performance of tests of publication bias and
other sample size effects in systematic
reviews of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-executive-summary.pdf
November 01, 2024 - Further, by focusing
only on studies rated low to moderate risk of bias, we limited the size of our
-
effectivehealthcare.ahrq.gov/sites/default/files/selection-of-data-sources-chapter-8.pptx
January 01, 2013 - identifier to indicate active ingredient(s), dosage and strength, route of administration, and package size … ingredient, the dosage form and route of administration, the strength of the product, and the package size … approach contrasts with data pooling and networking, which are tools primarily used to increase the size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
July 01, 2012 - Judging the overall quality of an individual study involves
examining the size of the study, the direction … of data analysis, applicability, whether ethics approval is specified, and
5-2
whether sample size … Judging the overall quality of an individual study involves examining the size of
the study, the direction
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_executive.pdf
May 01, 2013 - These studies compared different types of tubes
(e.g., design, materials, size), approaches to insertion … effect sizes and many researchers fail to report
their statistical power calculations of the sample size