-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
June 01, 2012 - The sample size of the randomized trials ranged from 82 11
to 806 7. … The sample size of the observational studies ranged from 40 13 to 149 5 participants. … [sample size =55]
The survival curves were nearly
identical for the two groups over 42
months. … Or 2) a trial not published in the above top 5 journals but have a sample size of at least triple the … a relative change in effect size of at least
50%.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - Primary orchiopexy is possible
if the testicle is of normal size and appearance and if the
testicular … intervention
• The effect on infertility/subfertility
• The development of testicular malignancy
• The size … intervention
• The effect on infertility/subfertility
• The development of testicular malignancy
• The size … information from observational
research)
• Precision (precise or imprecise based on outcome
rates, size … The most common outcomes were virilizing
effects (e.g., hair, increase in penis size, and erections)
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
September 21, 2012 - low power to detect
differences in subgroup effects.7 For example,
when compared with the sample size … required
for detecting ATE of a particular size, a sample
size roughly four times as large is required … difference in subgroup effects of the
same magnitude as ATE for a 50:50 subgroup split;
a sample size … Heterogeneity of Treatment Effects
outcome measures, thereby improving statistical
power for a given sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-reduction-asthma-evidence-summary.pdf
February 01, 2018 - We also need further
research on the interaction between the effect size of
outcome measures and meaningful
-
effectivehealthcare.ahrq.gov/sites/default/files/s44.pdf
October 01, 2007 - Aspects negotiated
by researchers and policymakers also deviated from ideal: length of
delay; size and … background, participants,
interventions, objectives
Joint decisions,
negotiated
Duration of delay, size … in the controls;
just one of DD trials had to collect
data by survey of patients
Outcomes, sample size … Size of Control Group. … ethical policy trial for coxibs would have
been a self-designing trial.24 In such trials, the final size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
May 08, 2013 - quality of the studies, we agree that there were many studies of poor
quality and/or small sample size … I don't
agree that it is realistic to apply an
arbitrary sample size of 50 subjects
for singlecentre … Unfortunately, most had
intermediate outcomes of
decreases in wound size. … We only see some changes in
wound size. … The authors did not
report what is a clinically
meaningful change in wound size.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
August 24, 2011 - labor pain management strategies used in U.S. hospitals –
stratified by number of yearly births and size … We set a cut-off level for study size for inclusion in the review at a minimum of 20 participants. … English only
Admissible evidence (study
design and other criteria)
Admissible designs
Study size … publication, study location (e.g., country, city, state) and time period, population
description, sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
April 03, 2013 - The effect size will change in such cases
depending on the follow-up time. … Studies with too small a sample size often
have other more covert problems as well. … Using one common effect size for all possible outcome measures would also help
with #3 above. … Biases of Success Rate Differences Shown in Binomial Effect Size
Displays. … Size of Treatment Effects and their Importance
to Clinical Research and Practice.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
November 06, 2012 - Specifically, because side effects of PT are rare
and not serious, we define the effect size to be … precise if the 95 percent CI of effect size does not
include 0. … For 95 percent CI of estimated
standardized effect size does include 0, the 95
percent CI should be … While in few
outcome comparisons the no PT involvement
groups had a larger effect size, in general … However, the sample size of most
pooled analyses decreased, and whether or not we
restricted to only
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
March 26, 2013 - Even if the
outcome rate is 10 percent (i.e., quite high), the sample size needs to be >400 patients … other effectiveness reviews and will include elements
that address population characteristics, sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
August 10, 2022 - permanent side effects in normal tissues, for palliative treatment, shorter courses of larger
fraction size … categories that include but
are not limited to: study design, year, setting, country, funding, sample size … characteristics including key subgroups (gender, age), primary tumor histology,
characteristics (e.g., size … This may be based on sample size sufficiency and number of
events. … When quantitative synthesis is not possible, sample size
and assessment of variance within individual
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - The major limitation of the systematic review was the lack of high-quality studies of
sufficient size … duration of interventions; lack
of statistical analyses beyond simple healing rates; lack of sample size … The evidence was insufficient to answer this
question due to the small number, small size, and
poor … The evidence was insufficient to answer this
question due to the small number, small size, and
poor … The duration and size of an ulcer
appear relevant to the effectiveness of certain dressings.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - Studies with documentation of coexisting
conditions and factors in trials with sufficient
sample size … Study Design
• Trials with sufficient sample size designed to
evaluate differential effectiveness … to evaluate
uncommon and serious harms would be a useful
supplement to RCTs, given likely sample size … • Studies with sufficient size to evaluate
differential effectiveness and safety of
treatments in
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-i.xlsx
January 01, 2019 - ICEMAN - Primary studies
RefID Study name State a single candidate effect modifier Was the effect modifier measured before or at randomization/assignment? State a single outcome and time-point of interest State a single effect measure 1: Was the direction of the effect modification correctly hypothesized a priori? 1: …
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain_disposition-comments.pdf
January 01, 2012 - The
sample size calculations provided were particularly helpful. … Fig. 1
(pg. 23) I did wonder about the high number of studies (n=548)
excluded due to low sample size … As the report notes in the Methods section, we
set a sample size cut off of 50 for treatment
studies … Even using a generous sample size
requirement of 50, few studies included
enough participants.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
January 01, 2016 - ,11 we rated evidence as precise
if the total number of patients exceeded the optimum
information size … If the total number of patients
exceeded the optimum information size and the 95% CI
did not exclude … For the main outcome of interest, CIN, we
used an optimum information size of 2,000, based on
an expected … For less frequent adverse outcomes, we used
an optimum information size of 10,000, based on an
expected
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
November 09, 2011 - pay-for-performance, and local sentinel events
b) Organization structural characteristics, such as size … relevant to both internal and external
validity, including study design, consistency of results, the size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
June 28, 2013 - provide # of studies, some indication of
quality/type of study, and perhaps something about sample size … of the
study so that readers can have some perspective on the size and
power of the study
We have … We have
therefore left off the sample size in the forest plots
but have instead included the number … After discussion with our statistician he confirmed
that the sample size within a forest plot can be … We have
therefore left off the sample size in the forest plots
but have instead included the number
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_technical-brief.pdf
January 01, 2012 - Study design/size.
c. … Study design/size. … wheeled mobility service delivery
Reference
Study Purpose Population Included Study Design
Sample Size … wheeled mobility service delivery
Reference
Study Purpose Population Included Study Design
Sample Size … mobility service delivery (continued)
Reference
Study Purpose Population Included Study Design
Sample Size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_clinician.pdf
August 01, 2016 - studies were mild or
moderate, but the ability of the studies to detect harms was
limited by their size … Disruptive
behaviors
3
(3 RCTs)
537 ��Significant change in disruptive behavior scores (effect size