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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
    June 01, 2012 - The sample size of the randomized trials ranged from 82 11 to 806 7. … The sample size of the observational studies ranged from 40 13 to 149 5 participants. … [sample size =55] The survival curves were nearly identical for the two groups over 42 months. … Or 2) a trial not published in the above top 5 journals but have a sample size of at least triple the … a relative change in effect size of at least 50%.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
    December 01, 2012 - Primary orchiopexy is possible if the testicle is of normal size and appearance and if the testicular … intervention • The effect on infertility/subfertility • The development of testicular malignancy • The size … intervention • The effect on infertility/subfertility • The development of testicular malignancy • The size … information from observational research) • Precision (precise or imprecise based on outcome rates, size … The most common outcomes were virilizing effects (e.g., hair, increase in penis size, and erections)
  3. effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
    September 21, 2012 - low power to detect differences in subgroup effects.7 For example, when compared with the sample size … required for detecting ATE of a particular size, a sample size roughly four times as large is required … difference in subgroup effects of the same magnitude as ATE for a 50:50 subgroup split; a sample size … Heterogeneity of Treatment Effects outcome measures, thereby improving statistical power for a given sample size
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-reduction-asthma-evidence-summary.pdf
    February 01, 2018 - We also need further research on the interaction between the effect size of outcome measures and meaningful
  5. S44 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s44.pdf
    October 01, 2007 - Aspects negotiated by researchers and policymakers also deviated from ideal: length of delay; size and … background, participants, interventions, objectives Joint decisions, negotiated Duration of delay, size … in the controls; just one of DD trials had to collect data by survey of patients Outcomes, sample sizeSize of Control Group. … ethical policy trial for coxibs would have been a self-designing trial.24 In such trials, the final size
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_disposition-comments.pdf
    May 08, 2013 - quality of the studies, we agree that there were many studies of poor quality and/or small sample size … I don't agree that it is realistic to apply an arbitrary sample size of 50 subjects for singlecentre … Unfortunately, most had intermediate outcomes of decreases in wound size. … We only see some changes in wound size. … The authors did not report what is a clinically meaningful change in wound size.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-nitrous-oxide_research-protocol.pdf
    August 24, 2011 - labor pain management strategies used in U.S. hospitals – stratified by number of yearly births and size … We set a cut-off level for study size for inclusion in the review at a minimum of 20 participants. … English only Admissible evidence (study design and other criteria) Admissible designs Study size … publication, study location (e.g., country, city, state) and time period, population description, sample size
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_disposition-comments.pdf
    April 03, 2013 - The effect size will change in such cases depending on the follow-up time. … Studies with too small a sample size often have other more covert problems as well. … Using one common effect size for all possible outcome measures would also help with #3 above. … Biases of Success Rate Differences Shown in Binomial Effect Size Displays. … Size of Treatment Effects and their Importance to Clinical Research and Practice.
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
    November 06, 2012 - Specifically, because side effects of PT are rare and not serious, we define the effect size to be … precise if the 95 percent CI of effect size does not include 0. … For 95 percent CI of estimated standardized effect size does include 0, the 95 percent CI should be … While in few outcome comparisons the no PT involvement groups had a larger effect size, in general … However, the sample size of most pooled analyses decreased, and whether or not we restricted to only
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
    March 26, 2013 - Even if the outcome rate is 10 percent (i.e., quite high), the sample size needs to be >400 patients … other effectiveness reviews and will include elements that address population characteristics, sample size
  11. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
    August 10, 2022 - permanent side effects in normal tissues, for palliative treatment, shorter courses of larger fraction size … categories that include but are not limited to: study design, year, setting, country, funding, sample size … characteristics including key subgroups (gender, age), primary tumor histology, characteristics (e.g., size … This may be based on sample size sufficiency and number of events. … When quantitative synthesis is not possible, sample size and assessment of variance within individual
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
    January 01, 2014 - The major limitation of the systematic review was the lack of high-quality studies of sufficient size … duration of interventions; lack of statistical analyses beyond simple healing rates; lack of sample size … The evidence was insufficient to answer this question due to the small number, small size, and poor … The evidence was insufficient to answer this question due to the small number, small size, and poor … The duration and size of an ulcer appear relevant to the effectiveness of certain dressings.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
    January 01, 2023 - Studies with documentation of coexisting conditions and factors in trials with sufficient sample size … Study Design • Trials with sufficient sample size designed to evaluate differential effectiveness … to evaluate uncommon and serious harms would be a useful supplement to RCTs, given likely sample size … • Studies with sufficient size to evaluate differential effectiveness and safety of treatments in
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-i.xlsx
    January 01, 2019 - ICEMAN - Primary studies RefID Study name State a single candidate effect modifier Was the effect modifier measured before or at randomization/assignment? State a single outcome and time-point of interest State a single effect measure 1: Was the direction of the effect modification correctly hypothesized a priori? 1: …
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pelvic-pain_disposition-comments.pdf
    January 01, 2012 - The sample size calculations provided were particularly helpful. … Fig. 1 (pg. 23) I did wonder about the high number of studies (n=548) excluded due to low sample size … As the report notes in the Methods section, we set a sample size cut off of 50 for treatment studies … Even using a generous sample size requirement of 50, few studies included enough participants.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_executive-2016.pdf
    January 01, 2016 - ,11 we rated evidence as precise if the total number of patients exceeded the optimum information size … If the total number of patients exceeded the optimum information size and the 95% CI did not exclude … For the main outcome of interest, CIN, we used an optimum information size of 2,000, based on an expected … For less frequent adverse outcomes, we used an optimum information size of 10,000, based on an expected
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-safety-practices_research-protocol.pdf
    November 09, 2011 - pay-for-performance, and local sentinel events b) Organization structural characteristics, such as size … relevant to both internal and external validity, including study design, consistency of results, the size
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
    June 28, 2013 - provide # of studies, some indication of quality/type of study, and perhaps something about sample size … of the study so that readers can have some perspective on the size and power of the study We have … We have therefore left off the sample size in the forest plots but have instead included the number … After discussion with our statistician he confirmed that the sample size within a forest plot can be … We have therefore left off the sample size in the forest plots but have instead included the number
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-service_technical-brief.pdf
    January 01, 2012 - Study design/size. c. … Study design/size. … wheeled mobility service delivery Reference Study Purpose Population Included Study Design Sample Size … wheeled mobility service delivery Reference Study Purpose Population Included Study Design Sample Size … mobility service delivery (continued) Reference Study Purpose Population Included Study Design Sample Size
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_clinician.pdf
    August 01, 2016 - studies were mild or moderate, but the ability of the studies to detect harms was limited by their size … Disruptive behaviors 3 (3 RCTs) 537 ��Significant change in disruptive behavior scores (effect size

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