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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
    July 13, 2011 - head comparisons: double-blind, placebo-controlled RCTs Minimum study duration 6 weeks Sample size … quality, controlled observational studies Minimum study duration For all studies: 3 months Sample size … 3 months Study population Adult inpatients and outpatients with recurrent depression Sample size … inpatients and outpatients with major depressive disorder, dysthymia, or subsyndromal depression Sample size
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
    April 01, 2012 - 1 Comparative Effectiveness Review Number 54 Drug Therapy for Psoriatic Arthritis in Adults: Update of a 2007 Report Executive Summary Background Psoriatic arthritis (PsA) is among the most disabling forms of arthritis, even though it affects fewer people than other types of arthritis. PsA has a highly variabl…
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
    January 10, 2012 - Sample Size Case studies with only one patient or very small numbers of patients (e.g., <20 patients … If there are large numbers of includable studies for the KQ(s), we may determine a minimum sample-size … into categories that include but are not limited to: study design, year, setting, country, sample size … Applicability will be estimated by examining the characteristics of the patient populations, the sample size
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
    May 01, 2016 - hollow-core needle, ranging in size from 11 to 16 gauge, to remove one or more pieces of breast tissue … The size, location, or imaging characteristics of a lesion may influence the choice of one breast biopsy
  5. S50 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
    October 01, 2007 - There is no minimal effect size in PBE-CPI studies; effect sizes change as we examine finer and finer
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_executive.pdf
    April 28, 2010 - ) Strength of Evidence Increased smoking No difference between groups (unable to calculate effect size … Moderate Anxiety No difference between groups (unable to calculate effect size). … , utilization, and other outcomes (continued) Type of Outcome Specific Outcome Results Effect Size … : Health, and utilization, and other outcomes Type of Outcome Specific Outcome Results Effect Size … Using drink size to talk about drinking during pregnancy: a randomized clinical trial of Early Start
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
    April 01, 2017 - clinical trial included women with screen-detected DCIS, low to intermediate nuclear grade, ≤2.5 cm size … or T1 DCIS Not allowed If all of the below: • Screen-detected • Low to intermediate nuclear grade • Size … 1 of the pathologic factors below and does not have any "unsuitable" factors Pathologic factors: • Size … 3.0 cm a • T2 • Close margins (b2 mm) • Limited/focal LVSI • ER(-) • Clinically unifocal with total size … and do not meet the criteria for cautionary Margins Positive No change DCIS N3 cm No change a The size
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_research-protocol.pdf
    January 01, 2020 - We will include studies published in English of any sample size, any design (randomized controlled trial … the evidence into summary tables/plots by population subgroup, vibration platform, study location, size … Distribution of the studies that examined the effects of vibration therapy by study design, sample size … comparators Vibration platform Vibration amplitude Vibration duration Study design Sample size
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
    January 01, 2006 - If relevant, the tables or text should include information on study design, sample size in each study … In addition, the individual evaluations should be weighted in some way (e.g., according to sample size … GI Safety in observational studies 149 Author, Year Sample size Population Duration (days … CV Safety in observational studies Author, Year Data source Sample size Population Exposure … CV Safety in observational studies Author, Year Data source Sample size Population Exposure
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
    March 24, 2017 - The sample size threshold is only for observational studies; RCTs of any size were eligible. … We clarified the text: “For KQ1-2: RCTs of any size and large prospective quasi-experimental cohort … Randomized controlled trials of any size were eligible. … We clarified the text: “For KQ1-2: RCTs of any size and large prospective quasi- experimental cohort … We agree that an effect size of 0.66 after 10 years is relatively large in magnitude, but it needs
  11. effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
    March 24, 2017 - The sample size threshold is only for observational studies; RCTs of any size were eligible. … We clarified the text: “For KQ1-2: RCTs of any size and large prospective quasi-experimental cohort … Randomized controlled trials of any size were eligible. … We clarified the text: “For KQ1-2: RCTs of any size and large prospective quasi- experimental cohort … We agree that an effect size of 0.66 after 10 years is relatively large in magnitude, but it needs
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
    September 11, 2015 - ratios (RRs) with corresponding 95% confidence intervals (CIs), as appropriate, and weighted by sample size … In adults <65 years, the effect size for behavioral programs compared with active controls at longest … The effect size for minority participants reached clinical importance.
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
    June 07, 2013 - We have restricted effect size values to 2 decimal places throughout the report. … articles still have English abstracts (at least in PubMed), providing some information like sample size … and effect size with confidence interval. … limitation), providing a summary table of this information from the abstract (to get at the sample size … It would be helpful to mention the sample size needed for a BRCA1+ population, which would be smaller
  14. effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
    February 01, 2008 - In evaluating all KQs, RCTs of any size or controlled observational trials enrolling ≥ 750 patients … Observational studies will be limited to those with a larger sample size given that most contemporary … Observational studies will be assessed for sample size, participant selection method, exposure measurement … when a meta-analysis is performed, we will evaluate the confidence interval around the summary effect size … Source: www.effectivehealthcare.ahrq.gov Published Online: August 06, 2010 had an adequate sample size
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
    February 01, 2008 - In evaluating all KQs, RCTs of any size or controlled observational trials enrolling ≥ 750 patients … Observational studies will be limited to those with a larger sample size given that most contemporary … Observational studies will be assessed for sample size, participant selection method, exposure measurement … when a meta-analysis is performed, we will evaluate the confidence interval around the summary effect size … Source: www.effectivehealthcare.ahrq.gov Published Online: August 06, 2010 had an adequate sample size
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
    August 27, 2012 - With the assistance of our content and technical experts, we selected a minimum sample size of 20 in … TEP #3 Methods Study size should indicate that criterion of n= 20+ refers to total sample (thus studies … The report states that it is a number to allow for sufficient effect size, but is that a statistical … With the assistance of our content and technical experts, we selected a minimum sample size of 20 in
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
    September 23, 2014 - from different specialities using EUS-FNA, CT, MRI, PET/PET-CT scan and DWI are difficult, as the size … The various diagnostic modalities should be compared only using patients with similar size profiles. … Little data is available with modalities other than EUS-FNA for accuracy based on tumor size, especially … The point about comparing the tests in patients with similar size profiles is well taken; it is one … Once again, the size of tumor is key in making such comparisons.
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
    October 10, 2019 - For patients with good prognosis (expected survival of 3 months or more), the number, size and resectability … Does the effectiveness depend on tumor size or radiation dose and fractionation and, and again, should … providers need to evaluate existing evidence on whether the effectiveness varies with tumor type, size … study), key question contribution (effects, adverse events, both), number of participants (study size … We will highlight the direction and size of effect narratively in addition to providing the numerical
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
    December 01, 2012 - Primary orchiopexy is possible if the testicle is of normal size and appearance and if the testicular … intervention • The effect on infertility/subfertility • The development of testicular malignancy • The size … intervention • The effect on infertility/subfertility • The development of testicular malignancy • The size … information from observational research) • Precision (precise or imprecise based on outcome rates, size … The most common outcomes were virilizing effects (e.g., hair, increase in penis size, and erections)
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-reduction-asthma-evidence-summary.pdf
    February 01, 2018 - We also need further research on the interaction between the effect size of outcome measures and meaningful

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