-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - head comparisons: double-blind, placebo-controlled RCTs
Minimum study duration
6 weeks
Sample size … quality, controlled observational studies
Minimum study duration
For all studies: 3 months
Sample size … 3 months
Study population
Adult inpatients and outpatients with recurrent depression
Sample size … inpatients and outpatients with major depressive disorder,
dysthymia, or subsyndromal depression
Sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_executive.pdf
April 01, 2012 - 1
Comparative Effectiveness Review
Number 54
Drug Therapy for Psoriatic Arthritis in Adults:
Update of a 2007 Report
Executive Summary
Background
Psoriatic arthritis (PsA) is among the most
disabling forms of arthritis, even though
it affects fewer people than other types
of arthritis. PsA has a highly variabl…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
January 10, 2012 - Sample Size
Case studies with only one patient or very small numbers of patients (e.g., <20 patients … If there are large numbers of includable studies for the KQ(s), we may
determine a minimum sample-size … into categories that include but
are not limited to: study design, year, setting, country, sample size … Applicability will be estimated by examining the characteristics of the patient populations,
the sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
May 01, 2016 - hollow-core needle, ranging in size from 11 to 16 gauge, to
remove one or more pieces of breast tissue … The size, location, or imaging
characteristics of a lesion may influence the choice of one
breast biopsy
-
effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
October 01, 2007 - There is no minimal effect size in PBE-CPI studies; effect
sizes change as we examine finer and finer
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_executive.pdf
April 28, 2010 - )
Strength of
Evidence
Increased smoking No difference between groups (unable to calculate effect size … Moderate
Anxiety No difference between groups (unable to calculate effect size). … , utilization, and other outcomes (continued)
Type of
Outcome
Specific
Outcome
Results
Effect Size … : Health, and utilization, and other outcomes
Type of
Outcome
Specific
Outcome
Results
Effect Size … Using drink size
to talk about drinking during pregnancy: a randomized clinical
trial of Early Start
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
April 01, 2017 - clinical trial included
women with screen-detected DCIS, low to intermediate
nuclear grade, ≤2.5 cm size … or T1
DCIS Not allowed If all of the below:
• Screen-detected
• Low to intermediate nuclear grade
• Size … 1 of the pathologic factors
below and does not have any "unsuitable" factors
Pathologic factors:
• Size … 3.0 cm a
• T2
• Close margins (b2 mm)
• Limited/focal LVSI
• ER(-)
• Clinically unifocal with total size … and do not meet the criteria for cautionary
Margins Positive No change
DCIS N3 cm No change
a The size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoporosis-vibration-therapy_research-protocol.pdf
January 01, 2020 - We will include studies published in English of any
sample size, any design (randomized controlled trial … the evidence into summary tables/plots by population subgroup,
vibration platform, study location, size … Distribution of the studies that examined the effects of vibration therapy by study design,
sample size … comparators
Vibration
platform
Vibration
amplitude
Vibration
duration Study design
Sample
size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - If relevant, the tables or text should include information on study design,
sample size in each study … In addition, the individual evaluations should be
weighted in some way (e.g., according to sample size … GI Safety in observational studies
149
Author, Year
Sample size
Population Duration
(days … CV Safety in observational studies
Author, Year
Data source
Sample size
Population Exposure … CV Safety in observational studies
Author, Year
Data source
Sample size
Population Exposure
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
March 24, 2017 - The sample size
threshold is only for observational studies;
RCTs of any size were eligible. … We clarified the
text:
“For KQ1-2: RCTs of any size and large
prospective quasi-experimental cohort … Randomized controlled trials of any size were
eligible. … We clarified the text: “For KQ1-2: RCTs
of any size and large prospective quasi-
experimental cohort … We agree that an effect size of 0.66
after 10 years is relatively large in magnitude,
but it needs
-
effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
March 24, 2017 - The sample size
threshold is only for observational studies;
RCTs of any size were eligible. … We clarified the
text:
“For KQ1-2: RCTs of any size and large
prospective quasi-experimental cohort … Randomized controlled trials of any size were
eligible. … We clarified the text: “For KQ1-2: RCTs
of any size and large prospective quasi-
experimental cohort … We agree that an effect size of 0.66
after 10 years is relatively large in magnitude,
but it needs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
September 11, 2015 - ratios (RRs) with corresponding
95% confidence intervals (CIs), as appropriate, and
weighted by sample size … In
adults <65 years, the effect size for behavioral programs
compared with active controls at longest … The
effect size for minority participants reached clinical
importance.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
June 07, 2013 - We have restricted effect size values to 2 decimal
places throughout the report. … articles still have English
abstracts (at least in PubMed), providing some
information like sample size … and effect size with
confidence interval. … limitation), providing
a summary table of this information from the abstract (to
get at the sample size … It would be helpful to mention the sample size
needed for a BRCA1+ population, which would be smaller
-
effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
February 01, 2008 - In evaluating all KQs, RCTs of any size or
controlled observational trials enrolling ≥ 750 patients … Observational studies will be limited to those with a larger sample size given that
most contemporary … Observational studies will be assessed for sample size, participant selection method,
exposure measurement … when a meta-analysis is performed, we will
evaluate the confidence interval around the summary effect size … Source: www.effectivehealthcare.ahrq.gov
Published Online: August 06, 2010
had an adequate sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
February 01, 2008 - In evaluating all KQs, RCTs of any size or
controlled observational trials enrolling ≥ 750 patients … Observational studies will be limited to those with a larger sample size given that
most contemporary … Observational studies will be assessed for sample size, participant selection method,
exposure measurement … when a meta-analysis is performed, we will
evaluate the confidence interval around the summary effect size … Source: www.effectivehealthcare.ahrq.gov
Published Online: August 06, 2010
had an adequate sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
August 27, 2012 - With the assistance of our
content and technical experts, we selected a
minimum sample size of 20 in … TEP #3 Methods Study size should indicate that criterion of n= 20+ refers to total
sample (thus studies … The report states that it is a number to allow for
sufficient effect size, but is that a statistical … With the assistance of our
content and technical experts, we selected a
minimum sample size of 20 in
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
September 23, 2014 - from different specialities using EUS-FNA, CT, MRI, PET/PET-CT scan and
DWI are difficult, as the size … The various diagnostic modalities should be compared only using
patients with similar size profiles. … Little data is available with modalities other
than EUS-FNA for accuracy based on tumor size, especially … The point about comparing the tests in patients with
similar size profiles is well taken; it is one … Once again, the size of
tumor is key in making such comparisons.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
October 10, 2019 - For patients with good prognosis (expected survival of 3 months or
more), the number, size and resectability … Does the effectiveness depend on tumor size or radiation dose and
fractionation and, and again, should … providers need to evaluate existing evidence on whether the effectiveness varies with
tumor type, size … study), key question
contribution (effects, adverse events, both), number of participants (study
size … We will highlight the direction and size of effect narratively in addition to providing the
numerical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - Primary orchiopexy is possible
if the testicle is of normal size and appearance and if the
testicular … intervention
• The effect on infertility/subfertility
• The development of testicular malignancy
• The size … intervention
• The effect on infertility/subfertility
• The development of testicular malignancy
• The size … information from observational
research)
• Precision (precise or imprecise based on outcome
rates, size … The most common outcomes were virilizing
effects (e.g., hair, increase in penis size, and erections)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-reduction-asthma-evidence-summary.pdf
February 01, 2018 - We also need further
research on the interaction between the effect size of
outcome measures and meaningful