-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
January 01, 2016 - most children, IH will
become apparent in the first few weeks of
life and reach 80 percent of total size … Specific disease characteristics, such as lesion size,
location, rate of growth, and persistence as … Lesion characteristics such as size, location,
and type (e.g., superficial, deep) also influence the … Studies comparing propranolol and steroids
to reduce IH size had conflicting findings. … Low SOE for effectiveness of PDL vs. observation in
reducing lesion size.
PDL vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-executive-sum.pdf
January 01, 2024 - Definitions of effect sizes
Effect Size Definition
No effect/trivial effect • Below thresholds for … placebo in the
short term (4 weeks to <6 months)
Product, THC to CBD Ratio
Pain Responsea
Effect Size … (N Studies)
[SOE]
Pain Severity
Effect Size (N Studies)
[SOE]
Function
Effect Size (N Studies … (N
Studies)
[SOE]
SAE
Effect Size (N
Studies)
[SOE]
Dizziness
Effect Size (N
Studies)
[SOE … ]
Nausea
Effect Size (N
Studies)
[SOE]
Sedation
Effect Size (N
Studies)
[SOE]
Comparable
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-pci-bypass_appendixes.pdf
October 06, 2006 - at randomization
CABG sample size at randomization
Group 1 outcome
1
Specify: Specify … at randomization
CABG sample size at randomization
Group 2 outcome
1
Specify: Specify … at randomization
CABG sample size at randomization
Group 3 outcome
1
Specify: Specify … at randomization
CABG sample size at randomization
Group 4 outcome
1
Specify: Specify … at randomization
CABG sample size at randomization
Group 1 outcome
2
Specify: Specify
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - Definitions of effect sizes
Effect Size Definition
Small effect • MD 0.5 to 1.0 points on a 0 to 10 … placebo in the
short term (4 weeks to <6 months)
Product, THC to CBD Ratio
Pain Response
Effect Size … (N Studies)
[SOE]
Pain Severity
Effect Size (N Studies)
[SOE]
Function
Effect Size (N
Studies … (N
Studies)
[SOE]
SAE
Effect Size (N
Studies)
[SOE]
Dizziness
Effect Size (N
Studies)
[SOE … ]
Nausea
Effect Size (N
Studies)
[SOE]
Sedation
Effect Size (N
Studies)
[SOE]
Comparable
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/scope-communicating-evolving-evidence-white-paper_0.pdf
June 01, 2025 - were available but there was
no change to findings (i.e., strength of evidence assessment or effect size … The TEP also emphasized the importance of highlighting
changes in effect size or strength of evidence … (N Studies)
[SOE]
Pain Severity
Effect Size (N Studies)
[SOE]
Function
Effect Size (N
Studies … (N
Studies)
[SOE]
SAE
Effect Size (N
Studies)
[SOE]
Dizziness
Effect Size (N
Studies)
[SOE … ]
Nausea
Effect Size (N
Studies)
[SOE]
Sedation
Effect Size (N
Studies)
[SOE]
Comparable
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-protein-intake-protocol-amendment.pdf
November 28, 2023 - screening, we will “tag” studies in PICO portal (using certain
identifiers, such as small sample size … direct link between intervention and outcome); 3) consistency (similarity of effect
direction and size … Population,
Intervention,
Comparator,
Outcome, Timing,
Setting/Study
Design (PICOTS)
Study Size … Thus, studies
performed in this
population will also be
included regardless of
sample size.
11/ … Thus, studies
performed in this
population will also be
included regardless of
sample size.
11/
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
December 01, 2024 - paroxetine for PTSD treatment
FDA
Study ID Corresponding Publication
Regulatory
Decision
Sample
Size … The
figures also illustrate differences in the lower confidence limit of the overall effect size: -7.02 … Effect Size Considerations: The likelihood of unpublished negative trials and the
likelihood that unpublished … Anticipated
effect size
Drugs with low
or small effect
sizes
Drug with high or large
effect sizes … Evidence size Few large trials
published
There are multiple large
good-quality trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/continuous-outcomes-quantitative-synthesis_methods.pdf
March 01, 2011 - Look up the sample size on Table 1 and use the given divisor. … For example, if the sample size
is 22, then SD could be estimated as range/3.819. … a sample size of 30 with a SD
of 7.53 for the mean difference. … Baseline distribution and
conditional size. J Biopharm Stat. 1993
Sep;3(2):265-76. … Estimation of effect size from a
series of independent experiments.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
July 01, 2017 - over another, patient factors (e.g., comorbidities,
life expectancy), tumor characteristics (e.g., size … for regional or distant metastases (���), some
other associations were observed:
�– Increased tumor size … 12 (9,401) A positive relationship between tumor size and malignancy
risk was found.
1.326 (1.220 … per tumor size in centimeters. … c The odds ratio represents the effect size per age in years.
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - Definitions of effect sizes
Effect Size Definition
Small effect • MD 0.5 to 1.0 points on a 0 to 10 … SOE
Function
Short Term
Effect Size SOE
QoL
Short Term
Effect Size SOE
Neuropathic
pain
Pregabalin … SOE
SNRIs (duloxetine/
milnacipran)
Intermediate Term
Effect Size SOE
TCAs
Short Term
Effect Size … SOE
NSAID
Intermediate
Term
Effect Size
SOE
NSAID
Long Term
Effect Size
SOE
Topical
Diclofenac … Effect Size
SOE
nsNSAID
Versus
Celecoxib
Long Term
Effect Size
SOE
WAE Small
++
None
+
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
January 01, 2024 - newly added studies had sample sizes ranging from 22 to 1,001,
with most studies (61%) having a sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - of 243 patients51 while a smaller
observational study reported no cases.19 Despite the large effect size … bias table
Author, Year
Related Studies
Trial ID
Location
Setting
Study Design
Study Size … 2024
C-2
Author, Year
Related Studies
Trial ID
Location
Setting
Study Design
Study Size … 2024
C-3
Author, Year
Related Studies
Trial ID
Location
Setting
Study Design
Study Size … 2024
C-4
Author, Year
Related Studies
Trial ID
Location
Setting
Study Design
Study Size
-
effectivehealthcare.ahrq.gov/sites/default/files/study-eligibility-criteria.ppt
January 01, 2000 - depression risk)
Country (United States only)
Setting (hospital-based studies only)
Study population size … Using Narrow Criteria
Can be helpful in culling homogenous literature
Can reduce size of the literature … size N ≥ 50 in each study at study start. … A total of 79 studies out of more than 2,000 were excluded on the basis of study size. … This decision was based on expert opinion and the size and scope of the literature.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/white-paper-roadmap-interventions.pdf
November 01, 2020 - .
• Five constructs (direction of effect, size of effect, clinical importance, statistical
significance … These two items were certainty of evidence and size of effect. … For example, the size
of an effect can affect the judgment about clinical importance. … Clinical importance and size of
effect may affect the determination of the direction of effect (e.g. … Judgments about the
clinical importance and size constructs are needed to determine the precision and
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-draft-appendices.pdf
January 01, 2025 - surveillance (CT scan, renal ultrasound, abdominal
radiograph) to detect radiographic stone recurrence, size … stone*”[tw] OR
“cystine calcul*”[tw] OR “struvite stone*”[tw] OR “struvite calcul*”[tw] OR “stone size … (less than 30 per arm)
Ala-Opas, 19875 Excluded for ineligible sample size (less than 30 per arm) … Barcelo, 19936 Excluded for ineligible sample size (less than 30 per arm)
Borghi, 19937 Excluded for … for ineligible sample size (less than 30 per arm)
Scholz, 198228 Excluded for ineligible sample size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
May 01, 2012 - See the following section regarding
sample size estimates. … See Table 3 in sample size section. … • Resource use, size, and duration
o This design option would require a sample size of at least … Sample size required to detect treatment effects in a 2x2 factorial design
Effect Effect size
Approximate … required to detect a treatment effect of a given size.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_clinician.pdf
June 01, 2016 - affected children, IH becomes
apparent in the first few weeks of life and reaches 80 percent
of total size … Conclusions
Propranolol is effective at reducing IH lesion size (i.e., lesion
clearance) when compared … Findings were limited by study size,
lack of standard processes, and lack of direct comparison at
the … of Treatment Interventions for Infantile
Hemangioma
Intervention Outcome Studies Finding Effect Size … Findings were
limited by study size, lack of standard processes, and lack
of direct comparison at the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dcis-prognostic-tests_research.pdf
August 22, 2012 - risk factors for DCIS progression and recurrence include com-
edo histology, younger age, larger tumor size … Tumor size: We defined tumor size using
the SEER collaborative staging tumor
extension field. … Women with DCIS also had a higher incidence of un-
known tumor size and grade (Table 1). … Likewise, the
association between tumor size and ER/PR testing dif-
fered between DCIS and invasive … In women with
invasive cancer, rates of ER/PR testing were relatively
stable across tumor size.
-
effectivehealthcare.ahrq.gov/sites/default/files/Evidence%20Summary_2.pdf
May 01, 2020 - We also did not include
interventions such as estimation of fetal size or
clinical pelvimetry which … use: Evidence summary for major outcomes and adverse events
Category Outcome
Study Design
(Sample Size … control: Evidence summary in women with unspecified
parity
Category Outcome
Study Design
(Sample Size … Moderate
(Imprecise)
11
Category Outcome
Study Design
(Sample Size) Conclusion
SOE
(Rationale … control: Evidence summary in women with
unspecified parity
Category Outcome
Study Design
(Sample Size
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-271-mental-health-pregnant-executive-summary.pdf
July 01, 2024 - treatments for depressive or anxiety disorders
Intervention Population Outcome Conclusion
Effect Size … (95% CI)
Effect Size, Back-
Transformed (95%
CI)
SoE
CBT vs. … 1.62,
0.06)
Insufficient
evidence
5
Intervention Population Outcome Conclusion
Effect Size … (95% CI)
Effect Size, Back-
Transformed (95%
CI)
SoE
CBT vs.