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41. Disposition of Comments_Comparative Effectiveness Review 255: Transitions of Care From Pediatric to Adult Services for Children With Special Healthcare Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/transitions-care-pediatric-to-adult-services-disposition-comments.pdf
    May 31, 2022 - We have detailed the domains in further detail in the appendix accompanying this table, Appendix G, … which outlines several of the domains identified by the reviewer (e.g., utilization, health-related … the Six Core Elements.” … and they are reflected in the Six Core Elements of HCT. … what is incorporated in the pediatric package of the Six Core Elements.

42. Making Healthcare Safer IV: Fatigue and Sleepiness of Clinicians Due to Hours of Service (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatigue-sleepiness-protocol.pdf
    July 01, 2023 - Making Healthcare Safer IV: Fatigue and Sleepiness of Clinicians Due to Hours of Service 1 … to hours of service? … translates into poorer performance by clinicians3 and ultimately contributes to medical errors.4 Thirty six … insufficient evidence base within healthcare settings, but fatigue management interventions from other work domains … the Cochrane Collaboration’s tool that cover the domains of selection bias, performance bias, detection

43. Treatment for Restless Legs Syndrome Disposition of Comments Report (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
    November 27, 2012 - MOS Sleep Scale: In study XP052, improvements in the total sleep score and all domains of the MOS sleep … There was a statistically significantly greater improvement in all domains of the MOS at Week 12 using … , placebo-controlled, six-week dose- finding trial in Europe. … a placebo-controlled trial longer than six months could raise questions that a relative benefit of … up to six months duration have be conducted for some RLS treatments, including rotigotine, pramipexole

44. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/dementia_hi_impact.pdf
    January 01, 2012 - change depending on expert comments received on interventions issued for comment during the preceding six … available; (2) information was compiled by November 2011 in this priority area; and (3) we received six … In this report, two new imaging agents are discussed from a class of six or seven similar positron … Results and Discussion of Comments Six experts, with research, clinical, and health systems backgrounds … , offered perspectives on florbetapir, and six different experts, with clinical, research, and health

45. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
    September 01, 2013 - of health care services. … of health care in the United States. … care quality. … 2, i.e., apply all six options to a sizable number of systematic reviews. … framework is quite general, in that it could be applied to methodological recommendations in other domains

46. Strategies To Reduce Cesarean | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/cesarean-birth-2010/research-protocol
    May 06, 2011 - Six open, active trials were identified in ClinicalTrials.gov that included cesarean birth rate as a … For RCTs, the fundamental domains will include: adequate sequence generation, allocation concealment, … Comparative Effectiveness Reviews , 10 which emphasizes the following four major domains: risk of bias … ratings for the individual domains. … of the final draft of the report.

47. S44 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s44.pdf
    October 01, 2007 - qualitative reassessment comprised: (1) applying criteria for reporting PRTs and (2) assessing DD trials in 3 domains … This led us to restructure our reassessment so that it covered 3 domains of responsibility: (1) policymakers … Key Elements in the Conduct of Two Designed Delay Trials in British Columbia Three Domains of Decisions … Six months of de- layed savings in 10% of nebulized medication users would equal 2.5 weeks of delayed … The Dictionary of the History of Ideas: Studies of Selected Pivotal Ideas. Vol 3.

48. #06 Developmental Delays ADHD, and Autism (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_autism_potential_high_impact_june_2012.pdf
    January 01, 2012 - No statement in this report should be construed as an official position of AHRQ or of the U.S. … the case of new applications of already-diffused technologies. … Perspectives of an expert with a COI are balanced by perspectives of experts without COIs. … phase III data were available; (2) information was compiled by April 15, 2012; and (3) we received six … They also subject patients to risks of adverse events, some of which could be serious.

49. Depression SSRI Surveillance Assessment_CER 62_Low-1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
    January 01, 2013 - The remaining six studies were abstracted into an evidence table (Appendix B).3-8 3.2 Expert Opinion … Opinion EPC Investigator Other Experts Conclusion from SCEPC Therapies in Adults There were six … Domains with the greatest variability included domain 3 (rigor of development), domain 5 (applicability … Combined Therapies Versus Combined Therapies in Adults There were six studies (n=832) for which … Domains with the greatest variability included domain 3 (rigor of development), domain 5 (applicability

50. Untitled (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
    October 05, 2015 - is closely followed as a quality-of-care measure, particularly for psychiatric patients in hospital … of quality of care.50 The Joint Commission reported in 2010 more than 200 deaths related to seclusion … at preventing aggressive behavior (e.g., implementation of a procedure informed by the NASMHPD’s Six … of!a!procedure!informed!by!the! NASMHPD’s!Six!Core!Strategies)! KQs!1b/1c!and!2b/2c:!Strategies! … of!a!procedure!informed!by!NASMHPD’s! Six!Core!Strategies)! KQ!3:!Same!as!KQs!1!and!2!

51. Nppv-Respiratory-Failure Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
    July 01, 2012 - ) Domains Pertaining to SOE Strength of Evidence Risk of Bias: Study Design/ Quality Consistency … Of these, four were of good quality, six were of fair quality, and two were of poor quality. … Summary of the strength of evidence for KQ 2—CPAP versus BPAP Number of Studies (Subjects) Domains … Number of Studies (Subjects) Domains Pertaining to SOE Strength of Evidence Risk of Bias: Study … Number of Studies (Subjects) Domains Pertaining to SOE Strength of Evidence Risk of Bias: Study

52. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
    November 01, 2016 - the following:4 Results from the trial show that after six months of treatment, both doses of elagolix … , at month three, as well as month six, as measured by the Daily Assessment of Endometriosis Pain scale … Treatment with peptide GnRH receptor agonists is usually limited to six monthly injections because … Results and Discussion of Comments Six experts, with clinical, research, health systems, and health … However, two experts were skeptical of clinician acceptance because of the lack of long- term data.16,21

53. - (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
    January 01, 2009 - sleep propensity in adult hypopituitary patients with growth hormone deficiency before and after six … 52 items across nine domains: physical functioning, social functioning, treatment issues, chest symptoms … Contains eight domains: physical functioning, role limiations due to physical problems, social functioning … between Jan 2000 and Jun 2003. 1 year Cox proportional hazards model %FEV1, best value within six … The six-minute walk test: a guide to assessment for lung transplantation.

54. final Fibromyalgia CER protocol_3-31-14 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
    April 03, 2014 - of Bias tool.53 The seven domains of the tool are sequence generation, allocation concealment, blinding … , and other sources of bias (i.e., problems not covered by other domains). … Published online: April 3, 2014 10 several of the domains but the study was blinded or, if … the three domains other than risk of bias. … Health status and disease severity in fibromyalgia: results of a six-center longitudinal study.

55. Systematic Review of Intermittent Inhaled Corticosteroids and of Long-acting Muscarinic Antagonists for Asthma (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
    December 27, 2016 - summarize the process and recommendations from their needs assessment.5 The Working Group identified six … Additional domains (plausible confounding, dose-response, and magnitude of effect) will be considered … Asthma control is determined by assessing the domains of impairment (patient self-reported symptoms, … by assessment of the impairment and risk domains. … risk domains.

56. Lung-Cancer-Nonsurgical-Therapies Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
    June 01, 2013 - bias.34 This system explicitly addresses four required domains: risk of bias, consistency, directness … Case series or single-arm studies were deemed indirect, imprecise, and “unknown” for the domains of … Additional domains, including strength of association, publication bias, coherence, dose-response relationship … Six single-arm studies were available. The risk of bias was high. … The strength of evidence for the six included RCTs is summarized in Table D.

57. Mass-Casualty-Events-Scarce-Resources Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
    June 01, 2012 - of health care in the United States. … care quality. … and Comparative Effectiveness Reviews.12 That approach requires assessment in four domains: risk of … All but one of the six studies we reviewed reported data collected from a single community. … No State plan addressed all four domains.

58. Acute Migraine Treatment in Emergency Settings | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/migraine-emergency/research-protocol
    July 18, 2011 - controlled trials. 20 The tool examines six domains (sequence generation, concealment of allocation … The overall assessment is based on the responses to individual domains. … If one or more individual domains are assessed as having a high risk of bias, the overall score will … Guide for Effectiveness and Comparative Effectiveness Reviews . 29 We will examine the following four domains … for each comparison, we will assign an overall evidence grade based on the ratings for the individual domains

59. EHC Research Protocol: Documentation Burden (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/documentation-burden-protocol.pdf
    July 26, 2023 - validity in the domains of reliability, consistency, and expected relations with other variables is … Collating and assessing evidence across these domains will inform efforts by health systems and standard-setting … Guiding Questions Description/Overview of measurements of documentation burden: 1) What metrics of … Discussions with Key Informants We plan to recruit six to nine KIs with different expertise, backgrounds … interactions and, subsequently, its effects on outcomes and quality of care.

60. Labor-Nitrous-Oxide Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/labor-nitrous-oxide_executive.pdf
    August 01, 2012 - We graded available evidence for each key outcome for each of the following domains: • risk of bias … Effect of Nitrous Oxide on the Route of Birth Six studies compared the route of birth in women who … ) Domains Pertaining to Strength of Evidence Strength of EvidenceRisk of Bias Consistency Directness … , 6 studies of fair quality, and 40 studies of poor quality total Note: Domains pertaining to SOE … Exposure to nitrous oxide in delivery suites at six Swedish hospitals.