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41. DEMENTIA INCLUDING ALZHEIMER'S #04 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/dementia_hi_impact.pdf
    January 01, 2012 - change depending on expert comments received on interventions issued for comment during the preceding six … available; (2) information was compiled by November 2011 in this priority area; and (3) we received six … In this report, two new imaging agents are discussed from a class of six or seven similar positron … Results and Discussion of Comments Six experts, with research, clinical, and health systems backgrounds … , offered perspectives on florbetapir, and six different experts, with clinical, research, and health

42. final Fibromyalgia CER protocol_3-31-14 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
    April 03, 2014 - of Bias tool.53 The seven domains of the tool are sequence generation, allocation concealment, blinding … , and other sources of bias (i.e., problems not covered by other domains). … Published online: April 3, 2014 10 several of the domains but the study was blinded or, if … the three domains other than risk of bias. … Health status and disease severity in fibromyalgia: results of a six-center longitudinal study.

43. Labor-Nitrous-Oxide Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/labor-nitrous-oxide_executive.pdf
    August 01, 2012 - We graded available evidence for each key outcome for each of the following domains: • risk of bias … Effect of Nitrous Oxide on the Route of Birth Six studies compared the route of birth in women who … ) Domains Pertaining to Strength of Evidence Strength of EvidenceRisk of Bias Consistency Directness … , 6 studies of fair quality, and 40 studies of poor quality total Note: Domains pertaining to SOE … Exposure to nitrous oxide in delivery suites at six Swedish hospitals.

44. EHC Protocol: Making Healthcare Safer IV: Opioid Stewardship (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
    July 01, 2023 - (NQF) identified fundamental actions to support opioid stewardship in healthcare organizations,5 six … Purpose of the Review The overall purpose of this review is to determine the effect of opioid stewardship … Cochrane Collaboration’s tool that cover the domains of selection bias, performance bias, detection … of the reported results.8 The risk of bias assessments will focus on the main outcome of interest … If any of the PSPs have more than one study of effectiveness, we will grade the strength of evidence

45. Disposition of Comments: Technical Brief No. 39_Disparities and Barriers to Pediatric Cancer Survivorship Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-39-pediatric-cancer-survivorship-comments.pdf
    March 01, 2021 - serve children and adolescents under a Medicaid demonstration program, providing care for at least a six-month … and quality and satisfaction with care captured in health services/ economic outcome domains. … We have edited the figures for GQs 4 and 5 so that they fully map to the outcome domains. … , but is not included under any of the outcome domains considered in the technical brief (it is noted … under the care domains of survivorship care plan, model of care, or survivorship care service.

46. #06 Developmental Delays ADHD, and Autism (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/06_devdelays_potential_high_impact_2012-12-10.pdf
    January 01, 2012 - No statement in this report should be construed as an official position of AHRQ or of the U.S. … the case of new applications of already-diffused technologies. … Perspectives of an expert with a COI are balanced by perspectives of experts without COIs. … available; (2) information was compiled by September 21, 2012, in this priority area; and (3) we received six … They also subject patients to risks of adverse events, some of which could be serious.

47. EHC Research Protocol: Documentation Burden (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/documentation-burden-protocol.pdf
    July 26, 2023 - validity in the domains of reliability, consistency, and expected relations with other variables is … Collating and assessing evidence across these domains will inform efforts by health systems and standard-setting … Guiding Questions Description/Overview of measurements of documentation burden: 1) What metrics of … Discussions with Key Informants We plan to recruit six to nine KIs with different expertise, backgrounds … interactions and, subsequently, its effects on outcomes and quality of care.

48. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
    November 01, 2016 - the following:4 Results from the trial show that after six months of treatment, both doses of elagolix … , at month three, as well as month six, as measured by the Daily Assessment of Endometriosis Pain scale … Treatment with peptide GnRH receptor agonists is usually limited to six monthly injections because … Results and Discussion of Comments Six experts, with clinical, research, health systems, and health … However, two experts were skeptical of clinician acceptance because of the lack of long- term data.16,21

49. Nppv-Respiratory-Failure Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
    July 01, 2012 - ) Domains Pertaining to SOE Strength of Evidence Risk of Bias: Study Design/ Quality Consistency … Of these, four were of good quality, six were of fair quality, and two were of poor quality. … Summary of the strength of evidence for KQ 2—CPAP versus BPAP Number of Studies (Subjects) Domains … Number of Studies (Subjects) Domains Pertaining to SOE Strength of Evidence Risk of Bias: Study … Number of Studies (Subjects) Domains Pertaining to SOE Strength of Evidence Risk of Bias: Study

50. Treatment for Restless Legs Syndrome Disposition of Comments Report (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_disposition-comments.pdf
    November 27, 2012 - MOS Sleep Scale: In study XP052, improvements in the total sleep score and all domains of the MOS sleep … There was a statistically significantly greater improvement in all domains of the MOS at Week 12 using … , placebo-controlled, six-week dose- finding trial in Europe. … a placebo-controlled trial longer than six months could raise questions that a relative benefit of … up to six months duration have be conducted for some RLS treatments, including rotigotine, pramipexole

51. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amendment.pdf
    February 05, 2025 - We also held discussions with six members of our Technical Expert Panel (TEP). … to assess risk of bias in randomized trials.37 The five domains of the tool are the randomization process … bias rating of “high,” “some concerns,” or “low” for each of the above domains and the overall risk … to a four-level scale by evaluating and weighing the combined results of the included domains. … Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section

52. Untitled (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
    October 05, 2015 - is closely followed as a quality-of-care measure, particularly for psychiatric patients in hospital … of quality of care.50 The Joint Commission reported in 2010 more than 200 deaths related to seclusion … at preventing aggressive behavior (e.g., implementation of a procedure informed by the NASMHPD’s Six … of!a!procedure!informed!by!the! NASMHPD’s!Six!Core!Strategies)! KQs!1b/1c!and!2b/2c:!Strategies! … of!a!procedure!informed!by!NASMHPD’s! Six!Core!Strategies)! KQ!3:!Same!as!KQs!1!and!2!

53. Mindfulness-Based Interventions for Wellbeing and Mental Health in Children and Adolescents: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ped-mindfulness-protocol-amended.pdf
    September 25, 2024 - We also held discussions with six members of our Technical Expert Panel (TEP). … to assess risk of bias in randomized trials.37 The five domains of the tool are the randomization process … bias rating of “high,” “some concerns,” or “low” for each of the above domains and the overall risk … to a four-level scale by evaluating and weighing the combined results of the included domains. … Below, we discuss the primary domains and how we will assess them: Risk of bias (see the above section

54. Mass-Casualty-Events-Scarce-Resources Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mass-casualty-events-scarce-resources_executive.pdf
    June 01, 2012 - of health care in the United States. … care quality. … and Comparative Effectiveness Reviews.12 That approach requires assessment in four domains: risk of … All but one of the six studies we reviewed reported data collected from a single community. … No State plan addressed all four domains.

55. Association Between Outcomes and Dental Services in People Receiving Treatments That Cause Medication-Related Osteonecrosis of the Jaw: A Rapid Response Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-jaw-rapid-response.pdf
    May 01, 2025 - system leaders, and policymakers, among others—make well-informed decisions and thereby improve the quality … of healthcare services. … dental treatment in relation to the development of MRONJ.39–44 Six cohort studies compared outcomes … the true population.39 The remaining six cohort studies, evaluated the occurrence of MRONJ in patients … of six academic societies: the Japanese Society for Bone and Mineral Research, Japan Osteoporosis

56. Urinary-Incontinence-Treatment Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
    October 29, 2012 - , and New England Journal of Medicine) and six specialty journals (Journal of Urology, International … We identified one RCT that demonstrated significant differences in three domains of quality of life … We identified one RCT that demonstrated significant differences in two domains of quality of life measure … Darifenacin Darifenacin significantly improved urgency UI and several domains of quality of life more … Darifenacin Darifenacin significantly improved urgency UI and several domains of quality of life more

57. Comparative Effectiveness of Strategies to De-escalate Aggressive Behavior in Psychiatric Patients in Acute Care Settings (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
    October 01, 2016 - restraints only as a last resort.14-22 Finally, using seclusion and restraints is closely followed as a quality-of-care … Directors’ Six Core Strategies.24 These Six Core Strategies ultimately aim to forestall or at least … posted on the Agency for Healthcare Quality and Research (AHRQ) Web site for public comment (www.effectivehealthcare.ahrq.gov … of care in such settings. … What is the role of quality measures, designed to create incentives to improve the quality of care,

58. Prostate-Cancer-Risk-Assessment-Genes Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-risk-assessment-genes_executive.pdf
    July 01, 2012 - of health care in the United States. … care quality. … The properties of a 5-SNP panel were investigated in six articles, four of which also considered family … Across six studies, the range of observed diagnostic ORs for the 5-SNP panel was 2.4 to 4.5. … moderate risk of bias. 5 Rating the Body of Evidence We considered the domains of risk of bias,

59. Traumatic-Brain-Injury-Rehabilitation Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
    June 01, 2012 - We evaluated SOE based on four required domains (risk of bias, consistency, directness, and precision … certain rehabilitation programs and compared results to those not participating in the program.30-33 Six … Six studies were conducted in the United States and two in other countries (United Kingdom and Finland … Six studies assessed comparative effectiveness with respect to productivity outcomes.35, 37, 41-43, … This would enable researchers to better define impairment domains and levels of impairment, which is

60. Future Research Needs for Diagnosis of Obstructive Sleep Apnea (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
    February 01, 2012 - well-informed decisions in designing and funding research and thereby improve the quality of health … care services. … of health care in the United States. … care quality. … six new topics.