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41. A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/primary-research-design/research
    January 01, 2019 - Step 2 provides a simple method to identify an existing systematic review which is current, valid, and

42. Brooks_ECCS2012 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/brooks_eccs2012.pdf
    January 01, 2012 - Slide 14: Simple Messages  (“Less  Is  More”) • Prostate cancer affects many men. • There are

43. Statistical Design and Analytic Considerations for N-of-1 Trials (Chapter 4) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-1
    August 01, 2019 - and treatment differences are clear, such simple methods work well; graphs are always informative, and … Nonparametric Tests The earliest n-of-1 trials in medicine used a simple nonparametric test called … In that case, the model becomes a simple two-mean model with random errors: Model 2: y ijkl = β … A simple check for carryover when the analyst has a sufficient number of observations taken over time … In the simple (and perhaps unrealistic) case that the outcomes are independent, the probability for the

44. Evidence Summary for CER 239: Acute Treatments for Episodic Migraine (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-239-acute-migraine-evidence-summary.pdf
    December 01, 2020 - butalbital-containing medications have a two-fold higher risk of medication overuse headache compared with simple … treatment for migraine and other recurrent headache disorders, and guidelines recommend that triptans and simple

45. Information Technology Infrastructure for N-of-1 Trials (Chapter 5) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014
    August 01, 2019 - work has addressed the procedures necessary to run individual trials using pen-and-paper techniques or simple … The system supports simple A-B treatment responses as well as multiphase withdraw/reversal or alternating … The service consists of a simple administrative dashboard to create and review user accounts. … 4 identifies a variety of options for performing statistical analysis of n-of-1 trials, including simple … n-of-1 trials with strong effects, it might be straightforward to analyze the trial outcomes using simple

46. Assessing Applicability (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
    January 01, 2009 - Applicability depends on context and cannot be assessed with a simple rating scale. … Applicability depends on context and cannot be assessed with a simple rating scale. … A simple and valid tool distinguished efficacy from effectiveness studies. … A simple and valid tool distinguished efficacy from effectiveness studies. … A simple and valid tool distinguished efficacy from effectiveness studies.

47. Noncyclic Chronic Pelvic Pain Therapies for Women: Comparative Effectiveness | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/pelvic-pain/research
    March 01, 2020 - interventions, there was no evidence that laparoscopic uterosacral nerve ablation (LUNA) is more effective than simple

48. Modeling to evaluate benefits and harms of new diagnostic tests compared to established diagnostic tests – uses and limitations (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/benefits-harms-modeling_research.pdf
    November 19, 2009 - an invasive procedure that was being considered for the differential diagnosis of suspected herpes simple … in real life, comprehensive enough to capture important behaviors of the simulated scenario and simple … A simple regression method proposed by Moses and Littenberg52 calculates a summary receiver operating … complex clinical scenarios can be modeled with suitable techniques that include but are not limited to simple

49. Frameworks for Determining Research Gaps During Systematic Reviews | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-future-research-steps-framework/research
    December 01, 2019 - We also developed a simple, user-friendly worksheet with instructions to facilitate the use of the framework

50. Allocation of Scarce Resources During Mass Casualty Events | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/mass-casualty-events-scarce-resources/research
    April 01, 2020 - In particular, the public believes that resource allocation guidelines should be simple and consistent

51. Quantitative Synthesis Chapter 3. Choice of Statistical Model for Combining Studies (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
    February 01, 2018 - A simple confidence interval for meta‐analysis. Stat Med. 2002;21(21):3153-9. … A simple confidence interval for meta‐analysis. Stat Med. 2002;21(21):3153-9. 6.

52. Assessing Applicability (ppt file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/assessing-applicability.ppt
    January 01, 2009 - Applicability depends on context and cannot be assessed with a simple rating scale. … Applicability depends on context and cannot be assessed with a simple rating scale. … A simple and valid tool distinguished efficacy from effectiveness studies. … A simple and valid tool distinguished efficacy from effectiveness studies. … A simple and valid tool distinguished efficacy from effectiveness studies.

53. Ebell_Presentation_REVISED_FINAL (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/use_of_handheld_ebell_presentation.pdf
    January 01, 2009 - • Expert  opinion   • Simple  calculators   • Multivariate  scores   • Point  scores  

54. CER 22 Rotator Cuff Tears NSD clean (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-nomination-140925.pdf
    March 20, 2014 - absorbable sutures § Bioabsorbable corkscrews vs. metal suture anchor § § Mattress locking vs. simple

55. Decision-Analytic Modeling to Evaluate Benefits and Harms of Medical Tests – Uses and Limitations | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/benefits-harms-modeling/research
    November 01, 2017 - an invasive procedure that was being considered for the differential diagnosis of suspected herpes simple … occur in real life, comprehensive enough to capture important behaviors of the simulated scenario and simple … A simple regression method proposed by Moses and Littenberg 52 calculates a summary receiver operating … complex clinical scenarios can be modeled with suitable techniques that include but are not limited to simple

56. Methods Guide for Medical Test Reviews Chapter 10 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
    July 01, 2012 - We discuss a simple algorithm for helping systematic reviewers think through this possibility, and illustrate … Figure 10–2 shows an outline of the management options in the form of a simple tree, for the clinical … of this figure is to outline the management options for positive and negative tests (here they are simple … we do not know of specialized hedges to identify 10-10 modeling studies, we suspect that even simple

57. Introduction to N-of-1 Trials: Indications and Barriers (Chapter 1) | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-4
    August 01, 2019 - This simple design allows for direct comparison of treatments A and B and protects against several forms … systematic review by Gabler et al., 32 approximately half of the trials reported using a t-test or other simple … Simple graphical analysis can transmit results clearly, but not all formats are equally understandable … Simple randomization (e.g., AABABBBA) optimizes blinding (more difficult to guess treatment), while balanced

58. Rotator-Cuff-Tear-Surveillance-140925 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-surveillance-140925.pdf
    February 01, 2014 - comparison of simple suture repairs to massive cuff stitch repairs for treatment of small- and … stitch MCS vs. simple stitch Visual analog scale for pain, activities of daily living, and UCLA … scores The clinical outcomes between the MCS and simple stitch were not significantly different. … irreparable rotator cuff tears suture of the cuff improvement: Simple Shoulder Test and Constant … There was moderate evidence for no difference in cuff integrity between mattress locking and simple

59. Methods for Benefit and Harm Assessment in Systematic Reviews | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/methods-balancing-harms-benefits/research-2012
    November 01, 2017 - the ratio of the number needed to treat to the number needed to harm, may be suitable for relatively simple

60. Slide 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
    August 27, 2012 -  Good validity and reliability for relatively simple trade-off problems.