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effectivehealthcare.ahrq.gov/sites/default/files/related_files/asd-medical-executive-170505.pdf
May 01, 2017 - e
Effective Health Care Program
2
Treatment of ASD
The manifestation and severity of symptoms of … What characteristics (e.g., age, symptom severity),
if any, of the child modify the effectiveness of … In two small trials, bumetanide
plus applied behavior analysis improved symptom severity
more than … Studies also included children with highly variable
severity of challenging behaviors, ASD symptom severity … Most
of the studies reported including children with at least
moderate level of severity of ASD.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/fibromyalgia_executive.pdf
January 01, 2015 - 2010 the ACR eliminated
the criterion of tender points examination
and added (1) physician-rated severity … on
two scales, the Widespread Pain Index
and the Symptom Severity Scale, and (2)
a requirement of … Two of three RCTs found no difference
in BPI average pain severity by race,3,63 but in one RCT
that … One duloxetine RCT with
high risk of bias reported 6-month changes in BPI average
pain severity for … Health status and disease
severity in fibromyalgia: results of a six-center longitudinal study.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - • Synthetic THC (high THC to CBD ratio) may be associated with moderate improvement
in pain severity … Comparable THC to
CBD Ratio Benefits
and Harms
Benefits: small improvements in
pain severity and … Synthetic High THC
to CBD Ratio
Benefits and Harms
Benefits: moderate
improvements in pain severity … Marijuana Use Is Not Associated With
Changes in Opioid Prescriptions or Pain
Severity Among People … Funnel Plot of High-THC Ratio Studies Included in Meta-Analysis for Pain Severity
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-research-protocol.pdf
April 11, 2018 - in
medication.”4 AECOPD are generally characterized by increased dyspnea, increased
frequency and severity … of cough, and/or increased sputum production.5 Exacerbations
may range in severity from mild to severe … " OR "increasing severity"
OR "increased seriousness" OR "increasing seriousness" OR exacerbation OR … " OR "increasing severity" OR "increased seriousness" OR "increasing
seriousness" OR exacerbation OR … " OR "increasing severity" OR
"increased seriousness" OR "increasing seriousness" OR exacerbation OR
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_disposition-comments.pdf
January 07, 2013 - Peer Reviewer #2 General KQ1: A key issue: Cough counting although a potential measure of
cough severity … Therefore, for the purpose of this
report, we considered instruments that
measured both severity and … QOL
together to be "severity/QOL"
instruments. … We evaluated
responsiveness of both frequency and
severity/QOL measures by reporting
data on changes … QOL
together to be "severity/QOL"
instruments.
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effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
January 01, 2012 - comparator selection is necessary to ensure validity of study results; confounding
by indication or severity … , confounding by indication
or severity poses a significant threat to the
validity of observational … Historical comparison groups will still be
vulnerable to confounding by indication or severity
when … information on indication or severity is
unmeasured. … When historical comparison groups are used, any
changes in the severity or operational definitions
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0260_07-16-2010.pdf
January 01, 2010 - Comparator(s): No treatment, placebo, or comparative effectiveness of treatments
Outcome(s): Reduced severity … Many
systematic reviews were identified that address individual interventions to reduce the severity
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - The effects
of quetiapine versus placebo for remission rates and for
global impressions of severity … SGAs likely increase response rates
and (slightly) clinical severity. … SGAs (and
risperidone) appear to reduce clinical severity, and they
probably reduce severity more for … A 6-point
reduction in tic severity using the Yale Global Tic Severity
Scale’s total tic score has … Limited evidence
suggests that SGAs are effective for reduction in tic
severity.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation_research-protocol.pdf
October 25, 2010 - Injury severity is determined through one or more
measures, including structural imaging findings, … Traumatic brain injury severity levels
Criteria Mild Moderate Severe
Structural Imaging Normal Normal … days
Glasgow Coma Scale (best
available score in 24 hours)
13–15 9–12 3–8
Abbreviated Injury Severity … Once a recovering patient’s impairment
severity and number of affected domains are lessened, rehabilitation … Definition of Terms
Abbreviated Injury Severity Scale (AIS)—Measure used to classify the severity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0277_03-10-2008.pdf
January 01, 2008 - Factors that impact the
appropriateness and success of any HSCT include the stage and/or severity of … Given the cost of treatment,
the severity of diseases that HSCT is used to treat, and the prevalence
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_surveillance.pdf
October 29, 2012 - What is the association between patient outcomes (continence, severity and frequency of
UI, quality … How do pharmacologic treatments affect continence, severity and frequency of UI, and
quality of life … Which patient characteristics, including age, type of UI, severity of UI, baseline disease
that affects … How do nonpharmacological treatments affect incontinence, UI severity and frequency,
and quality of … How do combined modalities of nonpharmacological treatments with drugs affect
incontinence, UI severity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0365_10-28-2010.pdf
January 01, 2010 - expressed
interest in how the effectiveness of treatments may differ by factors such as types and
severity … addition to wait list or placebo group participants
Outcome(s): Amelioration of symptoms (reduction in severity … reviews of treatment effectiveness by subpopulations of interest to the
nominator (including types and severity
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/ems-911-workforce-protocol.pdf
January 01, 2015 - What are the characteristics, incidence, prevalence, and severity of
occupationally-acquired exposures … How do the incidence, prevalence, and severity of exposures vary by
demographic characteristics (e.g … How do the incidence, prevalence, and severity of exposures vary by
workforce characteristics (e.g., … (Outcomes
of interest include but are not limited to, incidence, prevalence, duration,
severity, missed … (Outcomes of interest include but are not limited to, incidence, prevalence,
duration, severity, missed
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/impact-healthcare-algorithms-racial-ethnic-disparities-March-2.pdf
May 15, 2023 - • Leads to allocation of non
knee-based treatments
• But what do we mean by
‘disease severity’? … Pain
X-ray
Looks
normal
‘Not in the
knee’
Current SOTA
Measuring osteoarthritis severity … measure: –9%
• Adjusting for algorithmic
severity measure: –43%
► 4.7x more than standard
measure … (Y/N)
Primary Outcome
Severity of
Illness Scores
Applied to
Crisis
Standards of
Care
3
[Ashana … (Y/N)
Primary Outcome
Severity of
Illness Scores
Applied to Crisis
Standards of
Care
3
[Ashana
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/lysosomal-storage-diseases-therapies_research-protocol.pdf
November 15, 2012 - Data collected will include: study design, number of study
subjects, severity of disease, ERT dosing … Life expectancy depends on severity of
symptoms, ranging from <20 yrs to later adulthood,
with cause … The clinical course, disease progression, and
severity among the different organ systems vary
markedly … Life expectancy varies widely, depending on the
severity of symptoms, and can extend to near
normal … Severity of symptoms vary markedly
among pts.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
February 01, 2012 - Trials of CPAP stratified by disease severity.
b. … Analyses of CPAP stratified by disease severity
b. … Analyses of CPAP stratified by disease severity
b. … Analyses of CPAP stratified by disease severity
b. … Analyses of CPAP stratified by disease severity
b.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
April 03, 2014 - in two scales, the Widespread Pain Index and the Symptom Severity
Scale, plus symptoms present for … diagnostic criteria were
published in 2011 that eliminated physician estimates of somatic symptom severity … Fibromyalgia criteria and severity scales for
clinical and epidemiological studies: a modification of … Gender
differences in pain severity, disability, depression, and widespread pressure pain sensitivity … Health status and disease severity in fibromyalgia:
results of a six-center longitudinal study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-table-E-5.xlsx
January 01, 2023 - C Individual SF-36 domains; Individual depression and anxiety domains for HADS; BPI Pain Severity; EQ … B
BPI (0-10 scale [SD]): 5.1 (1.4) vs. 5.1 (1.8) Lagged mixed-effects linear regression: BPI pain severity … Mixed chronic pain (primarily non-cancer pain) Mixed Mean 47 53 NR NR NR NR NR NR NR 6; severity NR 761 … Pain VAS (0-10 scale [median, IQR]): 7.00 (6.00-8.00 [groups A and C]; 5.25-7.75 [group B])
BPI-Severity … converted to 0-10 scale)
4.4 (SD 1.46) Propensity matched on age, gender, stage of chronification, severity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-table-F5.xlsx
January 01, 2022 - C Individual SF-36 domains; Individual depression and anxiety domains for HADS; BPI Pain Severity; EQ … B
BPI (0-10 scale [SD]): 5.1 (1.4) vs. 5.1 (1.8) Lagged mixed-effects linear regression: BPI pain severity … Mixed chronic pain (primarily non-cancer pain) Mixed Mean 47 53 NR NR NR NR NR NR NR 6; severity NR 761 … Pain VAS (0-10 scale [median, IQR]): 7.00 (6.00-8.00 [groups A and C]; 5.25-7.75 [group B])
BPI-Severity … converted to 0-10 scale)
4.4 (SD 1.46) Propensity matched on age, gender, stage of chronification, severity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
October 01, 2021 - • Comparable THC to CBD ratio oral spray is probably associated with small
improvements in pain severity … • Synthetic THC (high-THC to CBD) may be associated with moderate
improvement in pain severity, no … In the short term (4 weeks to <6 months), small magnitude improvements in pain
severity and overall … In the short term, moderate
improvements in pain severity and no effect on overall function were found … In the short-term, moderate improvements in
pain severity were found with whole-plant extracted, high-THC