-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tinnitus_research-protocol.pdf
February 22, 2012 - Severity and Comorbidities
The severity of tinnitus experienced by patients may vary or depend on comorbidities … Measures
Various measures can be used to evaluate the presence and severity of the tinnitus.9 There … Tinnitus Handicap Inventory and the Tinnitus Reaction
Questionnaire are useful for grading tinnitus severity … Comparators
Different clinical evaluation methods used to characterize a diagnosis and measure severity … Guidelines for the grading of tinnitus severity: the results
of a working group commissioned by the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/delirium-disposition-comments.pdf
September 03, 2019 - TEP Peer
Reviewer #3
Clarity and
Usability
Third, while delirium severity was an agreed upon
outcome … However, it seemed to reviewers that the negative symbol
in the table next to delirium severity would … imply that
delirium severity was reduced by the antipsychotic. … The
concept of "slightly less improvement in severity than with
placebo" was hard to conceptualize … the reviewer that a patient’s length of
stay can be confounded by other variables such as
illness severity
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
March 01, 2022 - • Synthetic THC may be associated with moderate
improvement in pain severity, no effect on overall … e.g., identifying which
interventions are most effective for a given primary
substance of misuse, severity … , baseline severity of
behavioral and psychological symptoms of
dementia, and living setting. … Outcomes
• Studies should report asthma severity, comorbidity,
and socioeconomic factors and examine … Outcomes
• Outcome should include delirium severity, impact
on cognitive functioning, caregiver burden
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
June 01, 2012 - What are the patient characteristics, including etiology, predominant clinical
presentation, and severity … What are the patient characteristics, including etiology, predominant clinical presentation, and severity … support statements on whether
other clinical features (such as
demographics or indicators of RAS
severity … Medical therapy
Stenosis, Mean (range) — %
76 (40–100) vs. 75 (20–99) 0.29
Severity — no. … support statements on
whether other clinical features (such as demographics or
indicators of RAS severity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
January 01, 2019 - Several schema to
classify diverticulitis severity have been published,12 from the earliest one by Hughes … diagnosis but also with
prognosis.10, 11 Multiple other classification schemes exist that mostly stage severity … diverticulitis vs. other condition
o Complicated vs. uncomplicated diverticulitis
o For staging of severity … In particular, we will extract, as available, data on stage and
severity of acute diverticulitis (including … Impact of age on recurrence and severity of left
colonic diverticulitis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
October 01, 2012 - Dementia Severity and Other
Characteristics of the Person With Dementia
Two studies examined outcomes … of residents with
dementia in terms of dementia severity or socio-
demographic variables. … Hospitalization rates did not
differ by dementia severity for NH residents. … Hospitalization rates
did not differ by dementia severity for NH residents. … Only one study
considered the evidence in relation to the level of dementia
severity.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - comparable amounts of THC
and CBD in combination is probably associated
with small improvements in pain severity … • Synthetic THC may be associated with moderate
improvement in pain severity, no effect on
overall … Outcomes
• Future studies should include pain response,
pain severity, measures of overall function … estimates of treatment
effect that adequately account for important
confounders, such as age and severity … continue to be
important in identifying harms, researchers
should report more details about disease
severity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-executive-sum.pdf
January 01, 2025 - Extracted, comparable THC to CBD ratio oral spray is probably associated with
small improvements in pain severity … • Synthetic and purified THC (high THC to CBD) may be associated with small
improvement in pain severity … weeks to <6 months)
Product, THC to CBD Ratio
Pain Responsea
Effect Size (N Studies)
[SOE]
Pain Severity … 10
Product, THC to CBD Ratio
Pain Responsea
Effect Size (N Studies)
[SOE]
Pain Severity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
June 15, 2010 - not consistently
operationalized, but it is generally accepted that a 50 percent decrease in symptom severity … these therapies compare in different populations (for example, different depressive
diagnoses, disease severity … high-risk of bias vs. low- risk of bias) and clinical diversity (e.g.,
study population gender, disease severity … any potential differences in participants amongst the trials (e.g., age, gender,
diagnoses, disease severity … with sensitivity analyses (if meta-analyses can be undertaken) including the following: 1)
disease severity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
August 15, 2023 - reliability or validity (content,
construct, convergent, discriminant, divergent,
face)
OCD symptom severity … • Children’s Yale-Brown Obsessive
Compulsive Scale Total (CY-BOCS)*
• Clinical Global Impression–Severity … COVID-19 pandemic (as
defined by study authors)
o Duration of symptoms prior to treatment
o Symptom severity … Study Eligibility Criteria section, focusing on listed prioritized outcomes related to OCD
symptom severity … The prioritized outcomes include:
KQ 1
• Sensitivity/Specificity
KQ 2
• OCD symptom severity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_clinician.pdf
July 01, 2016 - cases and
feedback to health care teams, or clinical care algorithms)
for reducing the incidence or severity … heterogeneous across studies.
�� Some interventions were found to be effective in reducing
the incidence and severity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
March 15, 2010 - associated with an increased likelihood for motor vehicle and other accidents.15,16
Diagnosis
The severity … Does the comparative effect of treatments vary based on presenting patient
characteristics, severity … race, weight, bed partner, airway and other physical
characteristics, specific comorbidities
• OSA severity … time, resulting in uncertainty about what
constitutes “obstructive sleep apnea” and how to
define severity … The EPC will capture definitions of severity of sleep
apnea and will review the evidence in light of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-protocol-amendment.pdf
January 22, 2024 - Study Eligibility Criteria
Key Questions
Key Question 1: What are the incidence, prevalence, and severity … Are the incidence, prevalence, and severity modified by:
i. … KQ1= What are the incidence, prevalence, and severity of mental health issues (depression, anxiety, PTSD … For KQ 1 (incidence/prevalence/severity), for longitudinal studies, we will use items from the
Joanna … Because KQ 1 is
largely about
epidemiology
(incidence,
prevalence, and
severity), a sample
size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0210_12-07-2009.pdf
January 01, 2009 - are differences in the effectiveness or harms of these
treatments for specific subpopulations (e.g., severity
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0519_02-27-2012.pdf
January 01, 2012 - Patients with heart failure requiring hospitalization, including subgroups
based on age, symptom severity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
September 30, 2015 - problems): adjusted odds ratio 0.69, p=0.16 (treatment x time, adjusted for race and depression)
Pain severity … Pain condition: Chronic moderate to severe knee osteoarthritis pain (≥ 3 months)
Age: ≥55 years
Pain severity … weeks followup Multicenter
International Pain condition: Chronic low back pain
Age: ≥18 years
Pain severity … Pain condition: Moderate to severe osteoarthritis pain of the hip or knee
Age: NR
Pain severity: WOMAC … months Pain clinic
Netherlands Pain condition: Nonspecific chronic low back pain
Age: 18 to 75
Pain severity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/urinary-incontinence-treatment_executive.pdf
April 01, 2012 - What is the association between patient outcomes
(continence, severity and frequency of UI, quality … How do pharmacologic treatments affect continence,
severity and frequency of UI, and quality of life … Which patient characteristics, including age, type
of UI, severity of UI, baseline disease that affects … How do nonpharmacological treatments affect
incontinence, UI severity and frequency, and quality of … How do combined modalities of nonpharmacological
treatments with drugs affect incontinence, UI severity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
April 01, 2012 - Does the comparative effect of treatments vary based on presenting patient characteristics, severity … The
STOP-Bang equivalent model and prediction of
severity of obstructive sleep apnea: relation to … Does the comparative effect of treatments vary based on presenting patient characteristics, severity … CPAP
Subjective daytime
functioning, functional impact
of sleepiness, sleepiness,
fatigue severity … Does the comparative effect of treatments vary based on presenting patient characteristics, severity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-234-headaches-pregnancy-summary.pdf
November 01, 2020 - combination metoclopramide and diphenhydramine may be more effective
to reduce migraine or tension headache severity … with codeine, combination metoclopramide and
diphenhydramine reduced migraine or tension headache severity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_executive.pdf
January 01, 2020 - For each AE associated with a particular vaccine,
what is the average severity (grade 1/mild; grade 2 … For each AE associated with a particular vaccine,
what is the average severity (grade 1/mild; grade 2 … For each AE associated with a particular vaccine,
what is the average severity (grade 1/mild; grade 2 … (Many studies provided data on a
list of AEs but did not address severity.) … enough information for our investigators to
determine severity.