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  1. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary29/obstructive-sleep-apnea-in-adults-screening
    November 15, 2022 - (29 trials) or from mild to severe (16 trials). … only and mild only or mild to moderate vs mild to severe) ( Figure 3 ). … to moderate, moderate only and moderate to severe, and severe only) did not find a clear difference … , −2.21 for moderate only and moderate to severe, and −3.08 for severe only, and CIs overlapped; the … only or moderate to severe group ( Figure 3 ).
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Z6Rfj-qwfoMbuLp-hBmhzS
    May 01, 2021 - (29 trials) or from mild to severe (16 trials). … only and mild only or mild to moderate vs mild to severe) (Figure 3). … to mod- erate, moderate only and moderate to severe, and severe only) did not find a clear difference … only and moderate to severe, and −3.08 for severe only, and CIs overlapped; the analysis still found … to severe group (Figure 3).
  3. www.uspreventiveservicestaskforce.org/uspstf/recommendation/obstructive-sleep-apnea-in-adults-screening-january-2017
    January 24, 2017 - estimated prevalence of OSA in the United States is 10% for mild OSA and 3.8% to 6.5% for moderate to severeSevere OSA is associated with increased all-cause mortality; 6 however, the role OSA plays in increasing … OSA. 4 The prevalence of severe OSA in asymptomatic persons is unknown. … Based on prospective cohort studies, severe OSA has been found to be associated with a 2-fold increased … Screening for severe obstructive sleep apnea syndrome in hypertensive outpatients.
  4. www.uspreventiveservicestaskforce.org/uspstf/recommendation/chronic-obstructive-pulmonary-disease-copd-screening-2008
    March 15, 2008 - Fair evidence also indicates that fewer than 10% of those identified by screening spirometry have severe … or very severe COPD, using current diagnostic criteria. … or very severe COPD (FEV 1 <50% of predicted). … Risk Assessment Screening for COPD would theoretically benefit adults with a high probability of severe … or very severe COPD.
  5. untitled (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/VNs-WaxpPcsodxCb57gYmn
    January 03, 2017 - Severe OSA is associated with increased all-cause mortality, cardiovascular disease and cerebrovascular … moderate to severe OSA.1-3 Current prevalence may be higher, given the increasing prevalence of obesity … prevalence of severe OSA in asymptomatic persons is unknown. … Patients with severe untreated OSA have an increased risk of all-cause mortality. … Screening for severe obstructive sleep apnea syndrome in hypertensive outpatients.
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/QTJe7MfZ7cru9yYpxqx77m
    April 01, 2008 - or very severe COPD, using current diagnostic criteria. … or very severe COPD (FEV1 �50% of predicted). … to very severe COPD would benefit from pharma- cologic treatment to the same degree as symptomatic indi … Risk Assessment Screening for COPD would in theory benefit adults with a high probability of severe … or very severe COPD.
  7. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obstructive-sleep-apnea-in-adults-screening-january-2017
    January 24, 2017 - Comparing mortality for patients with severe or moderate to severe OSA vs controls, meta-analysis found … In multivariable analyses, all 3 studies reported that participants with severe or moderate to severe … People with severe (AHI ≥30) or moderate to severe (AHI ≥15) OSA had a hazard ratio for death of 2.07 … There was also consistent evidence showing that people with severe or moderate to severe OSA have increased … f Mild, 34%; moderate, 22%; severe, 25%.
  8. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/chronic-obstructive-pulmonary-disease-screening
    October 08, 2020 - patients with identified alpha-1 antitrypsin deficiency; pregnant women KQs 2, 3: Patients with severe … or very severe COPD; pregnant women; patients with identified alpha-1 antitrypsin deficiency … †Patients with severe disease would constitute a very small minority of those identified by asymptomatic
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rm4E5SooP2GnqJ_HVRA5M4
    January 01, 2017 - f Mild, 34%; moderate, 22%; severe, 25%. g At least mild (AHI �5 and ESS score >10), 25%; severe (AHI … Comparing mortality for patients with severe or moderate to severe OSA vs controls, meta-analysis found … In multivari- able analyses, all 3 studies reported that participants with severe or moderate to severe … People with severe (AHI �30) or moderate to severe (AHI �15) OSA had a hazard ratio for death of 2.07 … There was also consistent evidence showing that people with severe or moderate to severe OSA have increased
  10. www.uspreventiveservicestaskforce.org/uspstf/recommendation/hypertensive-disorders-pregnancy-screening
    September 19, 2023 - The presence of any systemic signs or symptoms of severe hypertension (systolic blood pressure ≥160 mm … Hg or diastolic blood pressure ≥110 mm Hg) is indicative of preeclampsia with severe features; HELLP … Hypertensive disorders of pregnancy can quickly evolve into severe disease that can result in serious … The timing of delivery depends on gestational age and whether severe features of preeclampsia are present … Contribution of hypertension to severe maternal morbidity. 
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/DxeDM5ywg2J7SwKmETXfbX
    May 01, 2021 - adults aged 30 to 70 years was 14% for men and 5% for women, and the estimated prevalence of moderate to severe … OSA (defined as AHI �15) was 13% for men and 6% for women.1 Severe OSA is associated with increased … adults aged 30 to 70 years was 14% for men and 5% for women, and the estimated prevalence of moderate to severeSevere OSA is associated with increased all-cause mortality. … Severe OSA is associated with increased all-cause mortality.
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/LNtA2SDWjpsDwjXvsH4F5m
    April 17, 2023 - The presence of any systemic signs or symptoms of severe hypertension (systolic blood pressure�160 mm … Hg or diastolic blood pressure �110 mm Hg) is indicative of preeclampsia with severe fea- tures; HELLP … syndrome is a severe form of preeclampsia that is di- agnosed based on a constellation of laboratory … Hypertensive disorders of pregnancy can quickly evolve into severe disease that can result in serious … Contribution of hypertension to severe maternal morbidity.
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/sDvjG49sFm7t3f3CnZUuFw
    October 04, 2005 - Severity 1-4 Minimal depression 5-9 Mild depression 10-14 Moderate depression 15-19 Moderately severe … depression 20-27 Severe depression PHQ9 Copyright © Pfizer Inc.
  14. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan102/chronic-obstructive-pulmonary-disease-screening-2016
    May 15, 2014 - patients with identified alpha-1 antitrypsin deficiency; pregnant women KQs 5–8: Patients with severe … (FEV 1 30%–49% normal) or very severe (FEV 1 <30% normal) COPD ‡ ; pregnant women; patients with COPD-related … § Patients with severe disease would constitute a very small minority of those identified by asymptomatic
  15. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/obstructive-sleep-apnea-in-adults-screening
    November 15, 2022 - adults aged 30 to 70 years was 14% for men and 5% for women, and the estimated prevalence of moderate to severe … OSA (defined as AHI ≥15) was 13% for men and 6% for women. 1 Severe OSA is associated with increased … and other cardiovascular risk factors), as well as the role of progression rates of OSA from mild to severe … test, sensitivity ranged between 88% and 92% and specificity ranged between 44% and 76% to predict severe … More data on the natural history of OSA; in particular, the rates of progression from mild to severe
  16. www.uspreventiveservicestaskforce.org/uspstf/recommendation/obstructive-sleep-apnea-in-adults-screening
    November 15, 2022 - Severe OSA is associated with increased all-cause mortality. … OSA (defined as AHI ≥15) was 13% for men and 6% for women. 1 Severe OSA is associated with increased … and other cardiovascular risk factors), as well as the role of progression rates of OSA from mild to severe … test, sensitivity ranged between 88% and 92% and specificity ranged between 44% and 76% to predict severe … More data on the natural history of OSA; in particular, the rates of progression from mild to severe
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/3XUeA-_n8KhYeS95ohoo2_
    August 03, 2020 - —Studies con¬ ducted in the developing world have documented outcomes associated with severe anemia during … the normal group (Hgb a89 g/L), 32% in the moderate anemia group (Hgb 75 to 88 g/L), and 42% in the severe … Stillbirths per 1000 births were 51 in the normal group and 150 and 147 in the moderate and severe anemia … The incidence of preeclampsia was 22% in women with severe anemia, compared with a gen¬ eral incidence … —A previously mentioned Kenyan study21 found that women with moderate to severe anemia (Hgb £88 g/L)
  18. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/iron-deficiency-anemia-in-pregnant-women-screening-and-supplementation
    July 07, 2022 - Outcomes KQ 1: Maternal health outcomes: Mortality; health-related quality of life; preeclampsia (severe … KQs 1, 3, 5: Maternal health outcomes: Mortality; health-related quality of life; preeclampsia (severe
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/mggnaKHr496c8QCgHe9-tm
    May 01, 2021 - Progression to severe disease can prevent participation in normal activities because of deteriora- tion … Progression to severe disease can prevent participation in normal activities because of deterioration … the postbronchodilator FEV1% pre- dicted; 80% or more is mild, 50% to 79% is moderate, 30% to 49% is severe … , and less than 30% is very severe. … The percent reduc- tion in the annual rate of moderate to severe exacerbations was higher for LABAs +
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/hEz3hmuzj-qYPRWLxucuPc
    during childhood and adolescence increases risk of skin cancer later in life, especially when more severe

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