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Showing results for "severe".

61. C- Evidence-based Practice Center Technical Brief Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/musculoskeletal-disorders-imaging_research-protocol.pdf
    August 05, 2010 - Suspected spinal stenosis: moderate/severe central stenosis (>1/3 canal) and lateral recess stenosis … Radicular pain: moderate/severe central stenosis, lateral recess stenosis, nerve root compression, … Non-specific spine pain: moderate/severe central stenosis, lateral recess stenosis, nerve root compression … recess stenosis (displacing or compressing nerve root, disc extrusion) • Radicular pain (moderate /severe … lateral recess stenosis, nerve root compression, disc extrusion) • Non-specific spine pain (moderate/severe

62. Evidence Summary: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-221-copd-evidence-summary_0.pdf
    October 01, 2019 - One uncertainty relates to the need for antibiotics in mild and moderately severe ECOPD, especially … in an outpatient setting.33 While antibiotics for treatment of severe ECOPD have been shown to be … Most studies were conducted in hospitalized patients with moderate to severe COPD. … The majority of studies were conducted in hospitalized patients with moderate or severe ECOPD with … Outcomes following acute exacerbation of severe chronic obstructive lung disease.

63. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - Infliximab: Discontinuation rates and severe adverse events higher with infliximab. … (Low) Insufficient evidence on differences in the risk for rare but severe adverse events. … (Low) Mixed evidence on differences in the risk for rare but severe adverse events. … Infliximab: Discontinuation rates and severe adverse events higher with infliximab. … (Low) Mixed evidence on differences in the risk for rare but severe adverse events.

64. Rheumatoid-Arthritis-Medicine Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - Infliximab: Discontinuation rates and severe adverse events higher with infliximab. … (Low) Insufficient evidence on differences in the risk for rare but severe adverse events. … (Low) Mixed evidence on differences in the risk for rare but severe adverse events. … Infliximab: Discontinuation rates and severe adverse events higher with infliximab. … (Low) Mixed evidence on differences in the risk for rare but severe adverse events.

65. PEPTIC ULCER #11 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pepticulcer_hi_impact.pdf
    January 01, 2012 - Monoclonal antibody (vedolizumab) for treatment of moderate to severe inflammatory bowel disease 3 … is no established “cure” for UC, a debilitating condition that can require surgery if it becomes severe … Patients with severe UC report paying $300 to $4,700 for a 10-week dose of pig whipworms ordered from … Treatment for severe SBS may involve oral rehydration solutions, intravenous nutrition delivery, and … In very severe cases, intravenous nutrition can be required indefinitely. 20 In cases where there

66. Stem-Cell-Children Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_executive.pdf
    February 01, 2012 - Griscelli syndrome type 2 Interferon-gamma receptor deficiencies Leukocyte adhesion deficiency Severe … alpha-mannosidosis Peroxisomal storage disorders Adrenoleukodystrophy Variable Allo NM Osteoporosis Severe … systemic lupus erythematosus (SLE), scleroderma, immune cytopenias, Crohn’s Upfront therapy for severe … natural history in patients with newly diagnosed type 1 juvenile diabetes mellitus or those with severe … single autologous HSCT for patients with newly diagnosed type I juvenile diabetes and patients with severe

67. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
    July 18, 2011 - systems and intracranial vasculature. 1 Acute exacerbations of episodic and chronic migraine cause severe … Of Americans with migraine, 7 percent reported using an ED or urgent care center for treatment of severe … Intermediate outcomes  Time in ED (hours)  Vital signs  Recurrence of severe symptoms/return … Use of the emergency department for severe headache. A population-based study. … Parenteral dexamethasone for acute severe migraine headache: meta-analysis of randomised controlled

68. Traumatic Brain Injury and Depression (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury-surveillance-160902.pdf
    January 30, 2014 - Prevalence"and"predictors"of"personality"change"after"severe" brain"injury." … $and$severe$to$mild"$moderate$ and$no$symptoms. … $PARTICIPANTS:$Individuals$with$ moderate$or$severe$TBI$(N=1662)$aged$16$years$or$older$consecutively … $ discharge,$of$individuals$ aged$40"49,$15.9%$ experienced$moderate$or$ severe$depressed$mood$ … $and$ severe$to$mild"$moderate$ and$no$symptoms.

69. Lysosomal-Storage-Diseases-Therapies Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/lysosomal-storage-diseases-therapies_research-protocol.pdf
    November 15, 2012 - may develop visceral problems (hepatomegaly, splenomegaly), anemia, thrombocytopenia, lung disease, severe … For clinical purposes, MPS II is divided into two forms, a severe form and an attenuated form. … - The more severe form has CNS involvement with symptoms presenting by 2 yrs of age. … The physical symptoms may include the same as the severe form, but are milder in nature. … Female carriers may be asymptomatic or have symptoms as severe as affected males.

70. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1506.pdf
    November 01, 2016 - Elagolix for Treatment of Endometriosis  Key Facts: Pharmacologic interventions for moderate or severe … Elagolix for Treatment of Endometriosis Unmet need: Pharmacologic interventions for moderate or severe … before using elagolix. 3 Clinical Pathway at Point of This Intervention Women with moderate to severe … A clinical study to evaluate the safety and efficacy of elagolix in subjects with moderate to severe … Study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate to severe

71. PREGNANCY, INCLUDING PRETERM BIRTH #12 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pregnancy-horizon-scan-high-impact-1512.pdf
    November 01, 2016 - Elagolix for Treatment of Endometriosis  Key Facts: Pharmacologic interventions for moderate or severe … Pharmacologic interventions for moderate or severe endometriosis include peptide gonadotropin-releasing … Clinical Pathway at Point of This Intervention Women with moderate to severe endometriosis may use peptide … Study to evaluate the long-term safety and efficacy of elagolix in subjects with moderate to severe … A clinical study to evaluate the safety and efficacy of elagolix in subjects with moderate to severe

72. Sleep-Apnea Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
    April 01, 2012 - (87%) and severe (70%) sleep disordered breathing, while the 4-Variable screening tool had higher … specificity to predict moderate –to-severe and severe sleep disordered breathing. … Australia Crossover RCT N=38, patients with obstructive sleep apnea in the upper moderate or severe … CPAP Sleep latency, reaction time and number of lapses, comfort In patients with severe obstructive … Kushida, 201113; USA Parallel RCT N=168, patients with moderate to severe obstructive sleep apnea

73. Migraine-Emergency Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
    November 01, 2012 - systems and intracranial vasculature.1 Acute exacerbations of episodic and chronic migraine cause severe … Furthermore, when the initial oral treatment for acute severe headaches fails, subsequent attempts … to assess the effectiveness of various parenteral medications for adult patients with moderate to severe … In other studies, patients self-rated their headache as moderate or severe. … Use of the emergency department for severe headache. A population-based study.

74. Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
    December 31, 2022 - meta-analysis, and data visualization that compared the risk of reinfection in adults with prior severe … IgG= Immunoglobulin G; SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2 What Is New? … In the Qatari cohort, previous infection was 87.8 percent effective in protecting against severe COVID … Factors affecting antibody response to SARS-CoV-2 in patients with severe COVID-19. … An Observational Cohort Study on the Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (

75. Disposition of Comments for CER 161 Major Depressive Disorder (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder-disposition-160504.pdf
    December 08, 2015 - John's wort as first line treatments for patients with moderate to severe MDD." This is confusing! … We acknowledge that there are a variety of definitions for a “severe” depressive episode, but a mean … of 19 on the HAM-D17 is commonly the threshold of what would be considered a severe MDD episode … of 19 on the HAM-D17 is commonly the threshold of what would be considered a severe MDD episode … For example, Roger McIntyre and Jay Nathanson in their book "Severe Depression" (Oxford University

76. Rapid Response_Linking Dental Services to Treatment Outcomes for Chronic Kidney Disease: A Rapid Response Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-outcomes-chronic-kidney-rapid-research.pdf
    November 01, 2024 - CKD stage 4 represents severe kidney damage. … CKD stage 5, representing severe kidney damage or failing kidneys and also termed as end stage kidney … Severe periodontitis affects more than 15 percent of American adults,8 constituting a major cause of … patients on dialysis in some studies11 suggesting that this is a near-ubiquitous comorbidity with severe … , PD (n=3), ND (n=6)# ; Low ↑ eGFR ↓ CRP ↓ IL6 da Silva 202124; 3; 3-5; Moderate – severe

77. App-D-Surv-Report-1-Noninvasive-Nonpharma 0 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-1-noninvasive-nonpharma_0.xlsx
    January 01, 2021 - ); Tumors (Rx Control); Diagnosed metabolic diseases; Previous neck surgery; Red flags (night pain, severe … with score >29 Hospital Anxiety and Depression questionnaire (HAD) (0-21, score => 11 moderate to severe … medication that could influence balance, associated pathologies such as alcoholism or severe … B Withdrawals due to severe knee pain: 0% (0/48) vs. 4.2% (2/48) AEs NR Scientific and Technological … paralysis, and schizophrenia; (f ) conditions that might interfere with treatment effects, such as severe

78. App-D-Surv-Report-2-Noninvasive-Nonpharma (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-2-noninvasive-nonpharma.xlsx
    January 01, 2021 - ); Tumors (Rx Control); Diagnosed metabolic diseases; Previous neck surgery; Red flags (night pain, severe … with score >29 Hospital Anxiety and Depression questionnaire (HAD) (0-21, score => 11 moderate to severe … medication that could influence balance, associated pathologies such as alcoholism or severe … B Withdrawals due to severe knee pain: 0% (0/48) vs. 4.2% (2/48) AEs NR Scientific and Technological … paralysis, and schizophrenia; (f ) conditions that might interfere with treatment effects, such as severe

79. Comparative Effectiveness of β-Adrenergic Antagonists on the Risk of Rehospitalization in Adults with Heart Failure (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-rehospitalization_research.pdf
    November 01, 2007 - The effect of spironolactone on morbidity and mortality in patients with severe heart failure. … Effect of carvedilol on survival in severe chronic heart failure. … Xamoterol in severe heart failure. The Xamoterol in Severe Heart Failure Study Group. … LUNG OSCR 49391.002 Bronchial asthma severe persistent LUNG OSCR 49391.004 Bronchial asthma acute … exacerbation LUNG OSCR 49391.005 Asthma/RAD severe persistent LUNG OSCR 49391.006 Asthma- severe persistent

80. Rapid Evidence Product: No-Touch Modalities for Disinfecting Patient Rooms in Acute Care Settings (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-no-touch-modalities.pdf
    May 01, 2022 - may use other mechanisms. 2 Since data directly assessing no-touch modalities for severe … For studies assessing impact on severe acute respiratory syndrome coronavirus (SARS-CoV), which emerged … Neurologic features in severe SARS-CoV-2 infection. N Engl J Med. 2020 Jun 4;382(23):2268-70. … acute respiratory syndrome coronavirus 2[tiab] OR severe acute respiratory syndrome corona virus 2 … acute respiratory syndrome'/de OR sars:ab,ti,kw OR 'severe acute respiratory syndrome':ab,ti,kw ─