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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
March 01, 2022 - compounds (PBCs), such as cannabinoids and kratom, used to treat chronic pain, addressing
concerns about severe … 9-Tetrahydrocannabinol/cannabidiol
(Sativex(R)): a review of its Use in patients
with moderate to severe … Treatment of severe
chronic pain with cannabis preparations. … Effectiveness and tolerability of
THC:CBD oromucosal spray as add-on
measure in patients with severe
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effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - conditions such as conduct disorders,
antipsychotics are usually given for adjunctive treatment
of severe
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amended.pdf
February 07, 2025 - Progression-free survival
• Nutritional assessment
• Quality of life, using validated scales
• Direct moderate-severe … prioritize
using summary measures for the purpose of analysis (e.g., incidence of any moderate to severe … grade the SOE for the following outcomes:
• Overall survival
• Quality of life
• Direct moderate-severe
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - regarding
liver injury, lactic acidosis, pancreatitis, hypoglycemia, congestive heart failure, cancer, severe … regarding liver injury, lactic acidosis, pancreatitis, hypoglycemia, congestive heart
failure, cancer, severe … injury
§ Lactic acidosis
§ Pancreatitis
§ Hypoglycemia
§ Congestive heart failure
§ Cancer
§ Severe … For the outcome of hypoglycemia, we will conduct separate analyses for: (a) severe
hypoglycemia and
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - threatening hypoglycemia leading to emergency
care or death; liver failure; congestive heart failure
(CHF); severe … conditions such as chronic renal insufficiency,
6
chronic liver disease, congestive heart failure, or severe … decrease in hematocrit was
small (1 g/dL) and would not be clinically relevant
except for subjects with severe … or borderline severe
anemia.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - Bias; Design/Quality Consistency Directness Precision Absolute Risk Difference per
100 Patients
Severe … The row identifying the outcome as a whole (e.g., severe diarrhea) also gives the overall rating (e.g … This slide depicts the magnitude of effect and strength of evidence grade for two outcomes: severe diarrhea … shows that 4 fair-quality randomized controlled trials (RCTs), with a total of 256 subjects, reported severe
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disabilities-quality-improvement-outcomes_executive.pdf
October 01, 2012 - Project Scope
Our scope did not include severe and persistent mental
illness as a primary diagnosis … , since the disability profile
and the cyclical nature of severe and persistent mental
illness suggest … community settings
Our exclusion criteria included:
• Inpatient settings
• Institutional settings
• Severe … The review
collected severity information (mild, moderate, severe,
chronic stable, frail, end stage
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-update_research-protocol.pdf
December 23, 2014 - CDI symptoms can range from mild diarrhea to severe
cases including pseudomembranous colitis and toxic … The vast majority of
severe morbidity and mortality is experienced in the elderly population.5,6 In … Vancomycin is recommended for severe initial incident CDI.19 However, both vancomycin and
metronidazole … Severe Clostridium difficile-associated
disease in populations previously at low
Source: www.effectivehealthcare.ahrq.gov
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
August 01, 2013 - The effects of sertraline on
severe tinnitus suffering--a randomized, double-blind, placebo-
controlled … The impact of sertraline
on health-related quality of life in severe refractory tinnitus: a
double-blind … A randomized trial
of nortriptyline for severe chronic tinnitus. … Effect of traditional Chinese
acupuncture on severe tinnitus: a double-blind, placebo-controlled,
clinical
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - Severe Adverse Events
The strength of the evidence on the comparative risks
of second-generation antidepressants … Other Severe Adverse Events
The existing evidence on the comparative risk for rare
but severe adverse … Severe adverse events
Comparative risk of suicidality Insufficient Results from 11 observational studies
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/protocol-pharm-pregnant-women_0.pdf
December 05, 2018 - following childbirth when compared with during pregnancy, suggesting
a potentially different etiology for severe … The authors suggest that
childbirth could serve as a “potent and highly significant trigger” of severe … by
indication, in that women who are receiving pharmacologic treatment may be likely to have more
severe … Open-label, proof-of-concept study of
brexanolone in the treatment of severe postpartum depression.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse_research-protocol.pdf
April 28, 2010 - women in the United
States reported recent use of alcohol.
18
It is generally accepted that less severe … , risky/hazardous drinking) are
appropriate for brief interventions in primary care, whereas more severe … Behavioral interventions and patient education are often used for patients who have less
severe alcohol … screening modalities (if any) are capable of distinguishing people with dependence from
those with less severe
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - ineffective in treating negative symptoms.7 Such symptoms
particularly play a critical role in producing the severe … Bipolar Disorder
Bipolar disorder is characterized by severe fluctuations in mood, activity, thought … of onset of 20 years.1 The APA
(2002) recommends the following treatment plan: 1) polytherapy for severe … Prochlorperazine Approved 1956 Schizophrenia
Severe nausea and
vomiting
Adults and children
Children
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf
January 01, 2024 - Progression-free survival
• Nutritional assessment
• Quality of life, using validated scales
• Direct moderate-severe … prioritize
using summary measures for the purpose of analysis (e.g., incidence of any moderate to severe … grade the SOE for the following outcomes:
• Overall survival
• Quality of life
• Direct moderate-severe
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-surveillance-report-3_0.pdf
May 01, 2022 - (PBCs), such as cannabinoids and kratom, used to treat chronic pain, and addresses
concerns about severe … Treatment of severe
chronic pain with cannabis preparations. … -
Tetrahydrocannabinol/cannabidiol
(Sativex(R)): a review of its Use in patients
with moderate to severe … Effectiveness and tolerability of
THC:CBD oromucosal spray as add-on
measure in patients with severe
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-chemotherapy-dental.pdf
July 01, 2023 - important for alerting the patient that
initiation of chemotherapy frequently leads to xerostomia, a severe … Some cancer treatments are associated with an increased risk of severe deterioration of
the bones of … Rates of moderate or severe mucositis were slightly
lower in the Dental Evaluation group in each day … Most participants
included in the studies had severe life-threatening types of cancer for which short-term … applicable Patients who received
dental care prior to bone
marrow transplantation
experienced less severe
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-translation-c-diff-treatment-clinical-pathway.pdf
November 01, 2019 - D5: Diagnose CDI
Severity Non-
Severe
Treatment
Selection
Diagnose patient presenting with non-recurrent … CDI as "CDI, non-
severe" if WBC<15,000 cells/mL AND Cr <1.5 mg/dl. … D6: Diagnose CDI
Severity Severe
Treatment
Selection
Diagnose patient presenting with non-recurrent … CDI as "CDI, severe" if
WBC>=15,000 cells/mL or Cr >=1.5 mg/dl. … Treatment recommendations for
non-severe and severe CDI were renamed as “non-fulminant”
7 X-ray recommendations
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
November 13, 2014 - non-pharmacologic treatments (e.g., increased agitation), are less frequent and severe … Elderly patients with dementia-related symptoms of severe
agitation and aggression: consensus statement
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-post-transplant-complications-rapid-research.pdf
May 01, 2025 - severity of
mucositis: a score of 0 indicates no mucositis, while a score of 5 indicates the most severe … significantly lower in the treatment group than
the control group (2.12 vs 2.56, p=0.001), indicating more severe … the severity of mucositis: a score of 0 indicates no mucositis, while a score of 5 indicates the most severe … Low-Level Laser Therapy
Prevents Severe Oral Mucositis in Patients
Submitted to Hematopoietic Stem … 77572012000200020
Timing of dental
care not of interest
Ferreira 2016 Low-level laser therapy prevents severe
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/anxiety-children_research-protocol.pdf
September 12, 2016 - lifetime prevalence between the
ages 13 and 18 years of 25.1% and a lifetime prevalence of 5.9% for "severe … used when psychotherapy is not available, does not lead to adequate response, or for
moderate or severe … another recommends they be used if CBT is not sufficient10, and the
third recommends their use for more severe