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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-evidence-summary.pdf
April 01, 2018 - Physiologic Predictors of Severe Injury: Systematic Review, Evidence Summary
Comparative Effectiveness … Review
Number 205
Physiologic Predictors of Severe Injury:
Systematic Review
Evidence Summary … Field hypotension in
patients who arrive at the hospital normotensive: a marker of
severe injury or … Prehospital shock index
and pulse pressure/heart rate ratio to predict massive transfusion
after severe … Physiologic
Predictors of Severe Injury: Systematic Review.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
April 20, 2022 - Hypertensive Disorders of Pregnancy, and Peripartum Magnesium Sulfate Regimens for Preeclampsia With Severe … Hypertensive Disorders of Pregnancy, and Peripartum
Magnesium Sulfate Regimens for Preeclampsia With Severe … that include preexisting chronic hypertension (HTN),
gestational HTN, preeclampsia with and without severe … features.16 Severe features of
preeclampsia include a severe-range BP (defined by the American College … Management of severe hypertension in pregnancy.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-264-maternal-morbidity-mortality-executive-summary.pdf
December 01, 2023 - morbidity; delivery location may
contribute up to 37 percent of ethnic disparity in severe maternal … o Nationally, if rural Indigenous birthing women experienced severe
maternal morbidity and mortality … maternal morbidity, contributing up to 37
percent of ethnic disparity in severe maternal morbidity … Neighborhood
racial and economic polarization, hospital of
delivery, and severe maternal morbidity. … Severe maternal morbidity and
mortality among indigenous women in the
United States.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19-appendix-table-B-1.xlsx
January 24, 2022 - any infection (n/N or % asymptomatic) Disease severity (hospitalized, not hospitalized; or mild/mod/severe … March 2020 Individuals who were vaccinated 32
Median (IQR)
Total: NR
Mild: 31 (29-59)
Moderately severe … : 127* (89.4)*
Severe: 13* (9.2)
Hospital admission: 122* (85.9)
LT
Non-severe: 63 (88.7)
Hospital admission … : 58 (89.2)
Hospital admission: 54 (83.1)
Control
Non-severe: 59 (90.8)
Hospital admission: 56 (86.2 … : 41
Mild: 42
Asymptomatic: 19
SOT
Severe: 22
Mild: 22
Asymptomatic: 9
IC
Severe: 19
Mild: 20
Asymptomatic
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-executive-summary.pdf
February 01, 2025 - depressive symptoms and stress were mild/low to moderate and mean
levels of burnout were mild to severe … (2.8% to 12.4%), and extremely severe (18.2%)
12 studies (11,089 participants) (moderate SoE)
Minimal … low personal
achievement (1% to 36.4%)
19 studies (10,977 participants) (moderate SoE)
Mild to severe … SoE)
Mild to severe general stress and operational and
organizational job stress. … Critical incidents 8 studies (5,511 participants) (low SoE)
Considerable variation for severe general
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-263-postpartum-hypertensive-pregnancy-executive-summary.pdf
May 01, 2023 - of disorders that include preexisting chronic HTN, gestational
HTN, preeclampsia with and without severe … now
understood that HDP can persist, worsen, or develop de novo after delivery, and may
result in severe … Individuals who develop preeclampsia with severe features are given MgSO4 to
prevent eclamptic seizures … Five RCTs evaluated
postpartum hospitalized patients with acute, severe HTN. … In six RCTs that enrolled patients with preeclampsia with severe features and
compared lower versus
-
effectivehealthcare.ahrq.gov/sites/default/files/clinical-pathway-methods-report-appendix-k.pdf
February 01, 2018 - CDI or if severe disease features
are present. … If severe, however, vancomycin should be used. … Provides protocol for daily assessment and dosing specifics for
both severe and non-severe symptoms. … Definition of severe Clostridium difficile infection. … • Severe CDI is defined as an episode of CDI with (1 or more specific signs and
symptoms of) severe
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
December 01, 2017 - Background
Patients with severe, persistent asthma are
managed with multiple medications that
may … intent of reducing excess airway
smooth muscle tissue in the airways and
reducing the frequency of severe … ,
a procedure that uses heat to remove
muscle tissue from the airways of
adults with moderate to severe … Relatively few randomized studies
have examined BT in patients with severe asthma and
addressed the … The evidence base was insufficient to draw
conclusions about BT’s effects on severe exacerbations,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
January 01, 2013 - Multidisciplinary Rehabilitation Programs for Moderate to Severe Traumatic Brain Injury in Adults: Future … Future Research Needs Paper
Number 36
Multidisciplinary
Rehabilitation Programs
for Moderate to Severe … Future Research Needs Paper
Number 36
Multidisciplinary Rehabilitation Programs for
Moderate to Severe … What is the effectiveness of postacute rehabilitation for moderate to severe TBI?
2. … What is comparative effectiveness of postacute rehabilitation for moderate to severe TBI?
3.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
January 10, 2012 - Since controversy surrounds the classification of
psoriasis as mild or moderate-to-severe, moderate-to-severe … Teva Pharmaceuticals
USA (Barr
Pharmaceuticals)
Symptomatic control of severe, recalcitrant, … erythema multiforme
(Stevens-Johnson syndrome), exfoliative dermatitis, mycosis fungoides, severe … Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis. … Methotrexate versus cyclosporine in
moderate-to-severe chronic plaque psoriasis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - We abstracted those at severity level 3, defined as " severe or medically
significant but not immediately … The other three studies of patients with severe COVID-
19 reported no significant difference. … Tocilizumab for treatment of patients with severe
COVID-19: A retrospective cohort study. … Convalescent
plasma treatment of severe COVID-19: a
propensity score-matched control study. … Tocilizumab
in Hospitalized Patients with Severe Covid-19
Pneumonia.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
January 01, 2009 - Preexisting: NR
-Gestational: 4.04%
Hypertension:
-Chronic: NR
-Gestational and preeclampsia without severe … 2.68% (listed as reason for IOL)
Hypertension:
-Chronic: NR
-Gestational and preeclampsia without severe … as reason for induction but type not specified)
-Chronic: NR
-Gestational and preeclampsia without severe … -Preexisting: NR
-Gestational: NR
Hypertension:
-Chronic: NR
-Gestational and preeclampsia without severe … -Preexisting: NR
-Gestational: NR
Hypertension:
-Chronic: NR
-Gestational and preeclampsia without severe
-
effectivehealthcare.ahrq.gov/products/predictors-trauma-care/research-2018
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation-surveillance-160902.pdf
May 29, 2025 - Multidisciplinary Postacute Rehabilitation for Moderate to Severe Traumatic Brain Injury in AdultsBrain … $Placebo"controlled$trial$of$amantadine$for$severe$
traumatic$brain$injury. … $Prevalence$and$predictors$of$personality$change$after$severe$
brain$injury. … $Severe$traumatic$brain$injury$in$Norway:$impact$of$
age$on$outcome. … $Severe$traumatic$brain$injuries$in$
Northern$Sweden:$a$prospective$2"year$study.
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effectivehealthcare.ahrq.gov/sites/default/files/pulmonary_hi_impact.pdf
April 01, 2012 - exacerbations experienced by patients with severe persistent asthma for at least 2 years.
7
The … or severe allergic asthma.
14
Some patients have severe asthma that
responds poorly to all forms … As a new treatment
modality BT may provide effective treatment for some patients with severe asthma … Persistence of effectiveness of bronchial
thermoplasty in patients with severe asthma. … in severe asthma (RISA) trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
December 14, 2017 - Airway Inflammation after Bronchial
Thermoplasty for Severe Asthma. … Finally, the authors did not
accurately differentiate severe from non-severe asthma. … The
evidence from the AIR trial on severe
exacerbations was insufficient and
inconclusive. … Cost effectiveness of bronchial thermoplasty in
patients with severe uncontrolled
asthma. … These data further demonstrate efficacy of BT
within this more severe population.
-
effectivehealthcare.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
August 27, 2012 - International Research Triangle Institute
Maximum Acceptable Breast-Cancer Risk
Vasomotor Symptoms
17
Severe … to
no symptoms
Severe to
mild symptoms
Severe to
moderate symptoms
0.025
M
a
x
im
u
m … International Research Triangle Institute
Maximum Acceptable Breast-Cancer Risk
Vasomotor Symptoms
18
Severe … to
no symptoms
Severe to
mild symptoms
Severe to
moderate symptoms
WHI Risk
0.025
M
a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation_executive.pdf
June 01, 2012 - Comparative Effectiveness Review
Number 72
Multidisciplinary Postacute Rehabilitation for
Moderate to Severe … The Department of Defense reported
more than 4,500 moderate to severe TBIs
among all service members … Criteria used to classify TBI severity7
Criteria Mild Moderate Severe
Structural Imaging Normal Normal … population lives with TBI-related disabilities, presumably
from moderate to severe TBI.10
Patients … Effects of
case management after severe head injury. BMJ. 1994 May
7;308(6938):1199-205.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar_research.pdf
August 01, 2015 - 2 * ‡
Non-severe hypoglycemia 0 *
Severe hypoglycemia 2 * ‡
Hyperglycemia 0 *
Adults
HbA1c 1 … HbA1c 0 *
Adherence 0 *
Non-severe hypoglycemia 0 *
Severe hypoglycemia 5 *
Hyperglycemia 0 … HbA1c 3 *
Adherence 0 *
Non-severe hypoglycemia 0 *
Severe hypoglycemia 1 *
Hyperglycemia 1 … 2 * ‡
Non-severe hypoglycemia 0 *
Severe hypoglycemia 2 * ‡
Hyperglycemia 0 *
Adults
HbA1c 1 … HbA1c 0 *
Adherence 0 *
Non-severe hypoglycemia 0 *
Severe hypoglycemia 5 *
Hyperglycemia 0
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
August 01, 2017 - .
�� FDA labels warn of several potential severe adverse
effects for all insomnia medications. … injuries because of drowsiness
�� Severe anaphylactic or anaphylactoid reactions
�� Possible respiratory … depression in people with severe lung disease
or sleep apnea
�� Withdrawal symptoms if abrupt dose … hallucinations)
�� Worsening depression or suicidal thoughts in people with
primary depression
�� Severe … � Decreased testosterone and increased prolactin levels
�� Possible adverse effects in people with severe