-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - that atypical antipsychotics can increase chances of adverse events such as significant weight
gain, sedation … Source: www.effectivehealthcare.ahrq.gov
Published Online: May 19, 2010
Tardive Dyskinesia
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - Pharmacologic and Nonpharmacologic Treatments of Posttraumatic Stress Disorder
Evidence-based Practice Center Systematic Review Protocol
Project Title: Pharmacologic and Nonpharmacologic Treatments of Posttraumatic Stress
Disorder
I. Background and Objectives for the Systematic Review
Posttraumatic stress…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-tables-e1-4.xlsx
January 01, 2024 - (Numerator) Intervention A, N Analyzed for Sedation (Denominator) Intervention A, % With Sedation Intervention … B, N With Sedation (Numerator) Intervention B, N Analyzed for Sedation (Denominator) Intervention B … , % With Sedation Intervention C, N With Sedation (Numerator) Intervention C, N Analyzed for Sedation … (Denominator) Intervention C, % With Sedation Intervention D, N With Sedation (Numerator) Intervention … D, N Analyzed for Sedation (Denominator) Intervention D, % With Sedation Intervention A, N of Cannabis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_executive.pdf
August 01, 2012 - Harms
or adverse effects reported in studies of antipsychotic
medications included sedation, gastrointestinal … depression.21,40,44 Adverse effects described in the study
of naltrexone included nausea, fatigue, sedation … in studies of SRIs included fatigue, tremor,
tachycardia, agitation, gastrointestinal complaints,
sedation … As in the case of efficacy, the data on adverse
effects associated with risperidone, including sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-tables-e1-4.xlsx
January 01, 2025 - (Numerator) Intervention A, N Analyzed for Sedation (Denominator) Intervention A, % With Sedation Intervention … B, N With Sedation (Numerator) Intervention B, N Analyzed for Sedation (Denominator) Intervention B … , % With Sedation Intervention C, N With Sedation (Numerator) Intervention C, N Analyzed for Sedation … (Denominator) Intervention C, % With Sedation Intervention D, N With Sedation (Numerator) Intervention … D, N Analyzed for Sedation (Denominator) Intervention D, % With Sedation Intervention A, N of Cannabis
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - resonance imaging (MRI), and
magnetic resonance (MR) angiography and venography,
some of which require sedation … Both techniques require
anesthesia or sedation. … Some approaches require sedation, and reported
success rates may reflect, in part, differences in the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - – General: extrapyramidal symptoms (EPS),
weight changes, agitation, constipation,
sedation, elevated … scores); positive, negative, and depressive
symptoms; relapse; quality of life; EPS; weight gain; and
sedation … Additionally, functional outcomes and symptomatic
outcomes (e.g., sedation, restlessness) were rarely
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - Side effects vary among the various medications, but
common side effects include dry mouth, sedation … • Weight gain (e.g., using Body Mass Index (BMI) growth charts)
• Agitation
• Constipation
• Sedation … events: extrapyramidal effects, weight gain (e.g., using BMI growth
charts), agitation, constipation, sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - Imaging approaches
include magnetic resonance angiography, which requires sedation or anesthesia and … Adverse effects, including but not limited to effects of sedation or anesthesia
Timing:
Timeframe
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2024-surv-rep-update-table-e5.xlsx
January 01, 2024 - C
Sedation
3 months: 31% (15/49) vs. 54% (28/52) vs. 33% (18/55), RR 0.57 (95% CI 0.35 to 0.93 for A … 1.29 (95% CI 0.75 to 2.21)
Nausea: 16.7% (36/215) vs. 9.7% (21/216), RR 1.72 (95% CI 1.04 to 2.85)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_clinician.pdf
August 01, 2016 - immediate in nature:
�– Adverse events frequently reported with risperidone
included weight gain, sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - amitriptyline
• SOE: Insufficient based
on 1 RCT
1 new RCT (n=70) found no
increase in SAEs, nausea, or
sedation … increase in cognitive AEs
• SOE: Low based on 8
RCTs
Large increase in dizziness,
peripheral edema, sedation … oral THC/CBD
associated with large increase in
WAEs, dizziness, nausea, but no
increase in SAEs or sedation … events, and liver or kidney-related harms for non-
steroidal anti-inflammatory drugs; weight gain, sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nv-hap-protocol.pdf
August 05, 2024 - prophylaxis, education of patients and caregivers and
staff, prophylactic antibiotics, minimizing sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-2025-surv-rep-update-table-e5.xlsx
January 01, 2025 - C
Sedation
3 months: 31% (15/49) vs. 54% (28/52) vs. 33% (18/55), RR 0.57 (95% CI 0.35 to 0.93 for A … 1.29 (95% CI 0.75 to 2.21)
Nausea: 16.7% (36/215) vs. 9.7% (21/216), RR 1.72 (95% CI 1.04 to 2.85)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
March 01, 2022 - There may be a large increased risk of
dizziness and sedation and a moderate increased
risk of nausea … with moderate
improvement in pain severity, no effect on overall
function, and increased risk of sedation … the
effect of antipsychotics on cognitive function,
delirium severity, or caregiver burden, or for
sedation … second-generation antipsychotics
used to prevent or treat delirium may lead to little
or no difference in sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - skilled nursing facility
Sitter use
Hospice enrollment
o Adverse effects of intervention(s)
Sedation … length
of stay in skilled nursing facility;
sitter use; hospice enrollment)
o Adverse effects (sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - There may be a large increased
risk of dizziness and sedation and a moderately
increased risk of nausea … associated with moderate
improvement in pain severity, no effect on
overall function, an increased risk of sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
June 01, 2013 - If the procedure becomes an outpatient procedure
performed under twilight sedation (more commonly known … as conscious sedation), as one clinical
expert from a facility with POEMs experience noted, the care-setting … The expert thought that POEM could be performed in an endoscopy suite under
moderate sedation and could
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-ape_0.xlsx
August 08, 2017 - -0.00 (-0.01 to 0.00)
Cognitive disturbance: SMD -0.16 (-0.21 to -0.10)
Nausea: 0.16 (0.14 to 0.19)
Sedation … placebo RD (95% CI)
WAE: -0.03 (-0.09 to 0.04)
SAE:0.00 (-0.05 to 0.05)
Nausea: 0.04 (-0.10 to 0.18)
Sedation … 0.00 (-0.01 to 0.01)
Cognitive disturbances: SMD -0.27 (-0.38 to -0.16)
Nausea: 0.19 (0.15 to 0.22)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/allergy-seasonal_research-protocol.pdf
March 08, 2012 - Nonselective antihistamines (e.g.,
diphenhydramine) bind central H1
receptors, which can cause sedation … Adverse effects, such as sedation,
are therefore reduced.27 The choice of which antihistamine to use … Nosebleeds
• Glaucoma
• Fracture
• Growth delay
• Hyperglycemia
• Urinary retention
• Palpitations
• Sedation … dryness, smell and taste abnormalities
• Selective and nonselective antihistamines
o Systemic effects: sedation