-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
October 01, 2014 - One review (Ching & Pringsheim, 2012) found
increased weight gain and higher risk ratios for
sedation … Notable side effects must be
considered, however, such as weight gain, sedation, drooling, and tremor … The most common AEs were sedation (26.5%),
somnolence (23.5%), headache (22.2%), and insomnia (13.6% … Eight patients (20.0%) experienced moderate to severe sedation and eight
(20.0%) experienced increased … For nearly all outcomes ratios for sedation and increased risk for weight regard to new evidence
and
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-pain-management-grand-rounds-slides.pptx
March 01, 2022 - Primary: efficacy outcomes (i.e., pain, overall function, adverse effects (e.g., dizziness, nausea, sedation … Size (N Studies)
[SOE]a Dizziness
Effect Size (N Studies)
[SOE]a Nausea
Effect Size (N Studies)
[SOE]a Sedation … Cannabis products associated with increased risk of adverse events (dizziness, sedation, nausea); studies
-
effectivehealthcare.ahrq.gov/sites/default/files/fraenkel.pdf
May 29, 2025 - http://www.effectivehealthcare.ahrq.gov/index.cfm) �
• Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
September 01, 2019 - events, such
as vomiting and subsequent airway
obstruction, respiratory depression,
hypotension, and sedation … at 15 min.
dInsufficient for drowsiness, changes in RAAS, reduced GCS, sleepiness/tired, confusion, sedation … , difficulty
concentrating.
eFor dizziness, sedation.
fInconclusive for mild sedation.
gFor dizziness
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-table-e5-2022-update_0.xlsx
January 01, 2022 - C
Sedation
3 months: 31% (15/49) vs. 54% (28/52) vs. 33% (18/55), RR 0.57 (95% CI 0.35 to 0.93 for A … 1.29 (95% CI 0.75 to 2.21)
Nausea: 16.7% (36/215) vs. 9.7% (21/216), RR 1.72 (95% CI 1.04 to 2.85)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
November 01, 2012 - acute migraine
Intervention Generic Name Trade Name(s) Mode of Administration
Agents for Procedural
Sedation … The results are presented by adverse
effect categories (e.g., sedation, dizziness, vomiting). … Sedation/Somnolence
Twenty-five studies reported on the development of
sedation/somnolence, including … The risk of developing sedation/
somnolence as a result of taking a placebo was 5 percent
(95% CI, 2 … The risk of
experiencing sedation following administration of
metoclopramide and prochlorperazine was
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - Duloxetine resulted in a large, dose-
dependent, increase in sedation (SOE: Moderate to
Low). … Additionally, pregabalin resulted in large increases
in risk of peripheral edema and sedation (SOE: … Duloxetine also resulted in increased sedation, but
lower doses did reduce the risk. … and
gabapentin resulted in moderate to large increases
in blurred vision, dizziness, weight gain, sedation … Additionally, pregabalin resulted in large
increases in risk of peripheral edema and sedation.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
July 18, 2011 - Addressing sedation as an adverse event. … Sedation/somnolence
b. Dizziness
c. Restless legs/akathisia
d. Anxiety
e. Vomiting
f. … Sedation/somnolence
2. Dizziness
3. Restless legs/akathisia
4. Anxiety
5. Vomiting
6. … in the ED, Visual Analog Scale score at discharge, and relapse after 48 hours)
and safety (e.g., sedation … interventions for acute migraine
Generic name Trade name(s) Mode of administration
Agents for procedural sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
August 01, 2013 - characteristics,
and symptoms
Comparative e�ectiveness of
treatment interventions
Worsening of tinnitus
Sedation … subjective loudness, quality of life, tinnitus severity, adverse effects (worsening
of tinnitus, sedation … subjective loudness, quality of life, return
to “normal” work, adverse effects (worsening of tinnitus, sedation … The findings for sedation were inconsistent
and imprecise, as estimates of affected patients were
poorly … characterized; the SOE for sedation was insufficient
in patients with tinnitus.
7
Table B.
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - FGAs are mainly
associated with dry mouth, sedation, and
extrapyramidal symptoms, which are
movement … cause
adverse effects including weight
gain, high triglyceride levels,
extrapyramidal symptoms, sedation … There may
be little or no difference between classes for sedation. … • Sedation. … There may be little or no difference between
olanzapine and risperidone for risk of sedation.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/suicide-prevention_research-protocol.pdf
December 23, 2015 - Untitled
Source: www.effectivehealthcare.ahrq.gov
Published online: December 23, 2015
Evidence-based Practice Center Systematic Review Protocol
Project Title: Suicide Prevention
I. Background and Objectives for the Systematic Review
Despite advances in the diagnosis and treatment of major mental disord…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-b.xlsx
May 29, 2025 - anticipated to be in the ICU for more than 48 hours; 2) Patients who had had any procedure(s) that required sedation … positive on the Confusion Assessment Method in the ICU tool; (4) Patients who had a Richmond Agitation-Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0215_01-06-2010.pdf
January 01, 2010 - Effective Health Care
Topic Number(s): 0239
Document Completion Date: 8-13-10
1
Results of Topic Selection Process & Next Steps
Treatment of restless legs syndrome will go forward for refinement as a systematic review. The scope
of this topic, including populations, interventions, comparato…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-apps-a-e-surveillance-report-2-final_0_0.pdf
March 01, 2022 - There may be a large increased risk of
dizziness and sedation, and a moderate increased risk of nausea … high THC to CBD) may be associated with moderate improvement in
pain severity and increased risk of sedation … no effect
on overall function/disability
(SOE: low; 2 RCTs)
Harms: moderate increased risk
of sedation … Combined THC/CBD may also be associated
with a moderate to large increased risk of dizziness, sedation … Sedation for comparable THC to CBD ratio versus placebo (short-term, 4 weeks to 6 months followup)
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-236-maternal-fetal-child-outcomes-disposition-comments.pdf
April 15, 2021 - In discussing the potential for adverse effects
with brexanolone, sedation and loss of consciousness
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F-5.xlsx
January 01, 2022 - C
Sedation
3 months: 31% (15/49) vs. 54% (28/52) vs. 33% (18/55), RR 0.57 (95% CI 0.35 to 0.93 for A … 1.29 (95% CI 0.75 to 2.21)
Nausea: 16.7% (36/215) vs. 9.7% (21/216), RR 1.72 (95% CI 1.04 to 2.85)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-table-F5.xlsx
January 01, 2022 - C
Sedation
3 months: 31% (15/49) vs. 54% (28/52) vs. 33% (18/55), RR 0.57 (95% CI 0.35 to 0.93 for A … 1.29 (95% CI 0.75 to 2.21)
Nausea: 16.7% (36/215) vs. 9.7% (21/216), RR 1.72 (95% CI 1.04 to 2.85)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs_research-protocol.pdf
December 16, 2011 - Mirapex
®
Yes
Ritigotine Neupro
®
Sedative-
hypnotics
Clonazepam Rivotril
®
Tolerance; sedation … Gabapentin Neurontin
®
Pregabalin Lyrica
®
Opioids Hydrocodone -Vicodin
®
-Lortab
®
Sedation
-
effectivehealthcare.ahrq.gov/health-topics/anesthesia
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_clinician.pdf
September 01, 2014 - .
Harms
� Aripiprazole and risperidone are associated with significant weight
gain, sedation,