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effectivehealthcare.ahrq.gov/products/antipsychotics/research-protocol
September 06, 2018 - skilled nursing facility
Sitter use
Hospice enrollment
Adverse effects of intervention(s)
Sedation … hospital; length of stay in skilled nursing facility; sitter use; hospice enrollment)
Adverse effects (sedation
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - Imaging approaches
include magnetic resonance angiography, which requires sedation or anesthesia and … Adverse effects, including but not limited to effects of sedation or anesthesia
Timing:
Timeframe
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_executive.pdf
December 01, 2012 - resonance imaging (MRI), and
magnetic resonance (MR) angiography and venography,
some of which require sedation … Both techniques require
anesthesia or sedation. … Some approaches require sedation, and reported
success rates may reflect, in part, differences in the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - Side effects vary among the various medications, but
common side effects include dry mouth, sedation … • Weight gain (e.g., using Body Mass Index (BMI) growth charts)
• Agitation
• Constipation
• Sedation … events: extrapyramidal effects, weight gain (e.g., using BMI growth
charts), agitation, constipation, sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - – General: extrapyramidal symptoms (EPS),
weight changes, agitation, constipation,
sedation, elevated … scores); positive, negative, and depressive
symptoms; relapse; quality of life; EPS; weight gain; and
sedation … Additionally, functional outcomes and symptomatic
outcomes (e.g., sedation, restlessness) were rarely
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preoperative-testing_executive.pdf
January 01, 2014 - both adults (≥18 years)
and children undergoing surgical procedures requiring
either anesthesia or sedation … elective or ambulatory surgical
or other invasive procedure that commonly requires
anesthesia or sedation … Cataract
surgery was included regardless of local practice
regarding anesthesia or sedation. … Patients undergoing nonsurgical diagnostic procedures
that may require anesthesia or sedation (e.g., … ophthalmologist’s office, that is minimally
invasive and usually requires only local anesthesia with
sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/draft-appendixes-plant-based-treatment.pdf
March 01, 2021 - pain,
function, disability, pain interference); harms and
adverse effects (e.g., dizziness, nausea, sedation … Sedation for comparable THC to CBD ratio versus placebo (short-term, 1 to 6 months followup)
Abbreviations … Sedation for high-THC versus placebo (short-term, 1 to 6 months followup)
Abbreviations: CI = confidence … Placebo
Sedation 6 RCTs
(N=866)1,2,4-7
Moderate Direct Consistent Imprecise Unknow n Large effect … dronabinol, not
statistically
signif icant
12% vs. 6%, RR
2.19 (0.77 to 5.39;
I²=0%)
Low
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pbt-lsr-appendixes.pdf
April 01, 2022 - pain,
function, disability, pain interference); harms and
adverse effects (e.g., dizziness, nausea, sedation … Sensitivity analysis of sedation for high-THC versus placebo (short term, 1 to 6 months followup) … Placebo
Sedation 6 RCTs
(N=866)1,2,4-7
Moderate Direct Consistent Imprecise Unknown Large effect … Placebo
Sedation 3 RCTs (N=335)9-
11
Moderate Direct Consistent Imprecise Unknown Moderate effect … Gabapentin
Alone)
Sedation 1 cohort study,
short- and
intermediate-term
(N=156)20
Moderate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - amitriptyline
• SOE: Insufficient based
on 1 RCT
1 new RCT (n=70) found no
increase in SAEs, nausea, or
sedation … increase in cognitive AEs
• SOE: Low based on 8
RCTs
Large increase in dizziness,
peripheral edema, sedation … oral THC/CBD
associated with large increase in
WAEs, dizziness, nausea, but no
increase in SAEs or sedation … events, and liver or kidney-related harms for non-
steroidal anti-inflammatory drugs; weight gain, sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - skilled nursing facility
Sitter use
Hospice enrollment
o Adverse effects of intervention(s)
Sedation … length
of stay in skilled nursing facility;
sitter use; hospice enrollment)
o Adverse effects (sedation
-
effectivehealthcare.ahrq.gov/products/ptsd-repository-expanded/protocol
February 14, 2020 - Current Page Topic Timeline Feb. 12, 2020 Topic Initiated Feb. 14, 2020 Research Protocol Nov. 4, 2020 Systematic Review Pharmacologic and Nonpharmacologic Treatments of Posttraumatic Stress Disorder
Research Protocol February 14, 2020 Download Main Document PDF 179.4 KB
I. Background and Objective…
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/renal-mass-and-localized-renal-cancer-the-following-questions-are-recommended-to-address-the-healthcare-tests-andor-treatments-this-program-should-consider-what-indicators-can-be-used-to-predict-malignancy-andor-aggressivenes
October 24, 2013 - Microwave vs. others
IV sedation / local anesthesia vs. general anesthesia
US vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-251-integrated-pain-management-evidence-summary.pdf
October 01, 2021 - Intergrated and Comprehensive Pain Management Programs: Effectiveness and Harms: Evidence Summary
Comparative Effectiveness Review
Number 251
Integrated and Comprehensive Pain
Management Programs: Effectiveness and
Harms
Evidence Summary
Main Points
Background and Purpose
Pain affects millions …
-
effectivehealthcare.ahrq.gov/products/antipsychotics-adults/research-protocol
December 01, 2010 - terms of extrapyramidal side effects and tardive dyskinesia, but produce other side effects, including sedation … General: extrapyramidal side effects, weight gain, agitation, constipation, sedation, elevated cholesterol … General adverse events : extrapyramidal effects, weight gain, agitation, constipation, sedation, elevated
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
June 01, 2013 - If the procedure becomes an outpatient procedure
performed under twilight sedation (more commonly known … as conscious sedation), as one clinical
expert from a facility with POEMs experience noted, the care-setting … The expert thought that POEM could be performed in an endoscopy suite under
moderate sedation and could
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-ape_0.xlsx
August 08, 2017 - -0.00 (-0.01 to 0.00)
Cognitive disturbance: SMD -0.16 (-0.21 to -0.10)
Nausea: 0.16 (0.14 to 0.19)
Sedation … placebo RD (95% CI)
WAE: -0.03 (-0.09 to 0.04)
SAE:0.00 (-0.05 to 0.05)
Nausea: 0.04 (-0.10 to 0.18)
Sedation … 0.00 (-0.01 to 0.01)
Cognitive disturbances: SMD -0.27 (-0.38 to -0.16)
Nausea: 0.19 (0.15 to 0.22)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/allergy-seasonal_research-protocol.pdf
March 08, 2012 - Nonselective antihistamines (e.g.,
diphenhydramine) bind central H1 receptors, which can cause sedation … Adverse effects, such as sedation,
are therefore reduced.27 The choice of which antihistamine to use … Nosebleeds
• Glaucoma
• Fracture
• Growth delay
• Hyperglycemia
• Urinary retention
• Palpitations
• Sedation … dryness, smell and taste abnormalities
• Selective and nonselective antihistamines
o Systemic effects: sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/labor-nitrous-oxide_executive.pdf
August 01, 2012 - given intravenously or by
intramuscular injection
• Provides some relief of labor pain and
causes sedation
-
effectivehealthcare.ahrq.gov/products/nonopioid-chronic-pain/protocol
March 01, 2019 - cardiovascular events, and liver or kidney-related harms for non-steroidal anti-inflammatory drugs; weight gain, sedation … kidney and liver-related harms with NSAIDs, weight gain, dry mouth/blurred vision, cognitive effects, sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
January 01, 2023 - There may be a large increased
risk of dizziness and sedation and a moderately
increased risk of nausea … associated with moderate
improvement in pain severity, no effect on
overall function, an increased risk of sedation