-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendix-f2-surveillance-report-1.xlsx
November 22, 2021 - Cognitive Effects Cognitive Effects Cognitive Effects Cognitive Effects Dry Mouth Dry Mouth Dry Mouth Sedation … Sedation Sedation Sedation Dizziness Dizziness Dizziness Weight Gain Weight Gain Weight Gain
Author … Cognitive Effects Dizziness Dizziness Dizziness Peripheral Edema Peripheral Edema Peripheral Edema Sedation … Sedation Sedation Sedation Weight Gain Weight Gain Weight Gain
Author, Year Quality Pain Population
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effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
December 01, 2014 - using Sedasys to benzodiazepine/opiate-mediated sedation. … Endoscopist/nurse teams administered both sedation methods. … of propofol for sedation during endoscopies, experts also
commented. … compared with benzodiazepine/opioid
sedation. … An
assessment of computer-assisted personalized
sedation: a sedation delivery system to administer
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1406.pdf
June 01, 2014 - delivered using Sedasys to benzodiazepine/opiate-mediated sedation. … sedation during routine endoscopy procedures. … Endoscopist/nurse
teams administered both sedation methods. … compared with benzodiazepine/opioid sedation. … An assessment of computer-assisted personalized
sedation: a sedation delivery system to administer
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
September 20, 2022 - Drug Assessment Time (Wk) Time Category WAE: n WAE: N SAE: n SAE: N Nausea: n Nausea: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Dry Mouth: n Dry Mouth: N N Randomized Dizziness: … : Specific AE Sedation: n Sedation: N N Randomized Dizziness: n Dizziness: N N Randomized Weight Gain … Randomized Dizziness: n Dizziness: N N Randomized Peripheral Edema: n Peripheral Edema: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Weight Gain: n Weight Gain: N N Randomized
Khasbage
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
September 20, 2022 - Specific AE Cognitive Effects: n Cognitive Effects: N N Randomized Dry Mouth: n Dry Mouth: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Dizziness: n Dizziness: N N Randomized Weight Gain … Randomized Dizziness: n Dizziness: N N Randomized Peripheral Edema: n Peripheral Edema: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Weight Gain: n Weight Gain: N N Randomized
Lee, 2020
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
September 20, 2022 - Specific AE Cognitive Effects: n Cognitive Effects: N N Randomized Dry Mouth: n Dry Mouth: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Dizziness: n Dizziness: N N Randomized Weight Gain … Randomized Dizziness: n Dizziness: N N Randomized Peripheral Edema: n Peripheral Edema: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Weight Gain: n Weight Gain: N N Randomized
Khasbage
-
effectivehealthcare.ahrq.gov/products/migraine-emergency/research
November 27, 2012 - The risk of sedation following administration of metoclopramide or neuroleptic agents was 17 percent. … The most common short-term side effects for triptans were skin reactions, local reactions, and sedation … For patients receiving DHE, the most common side effects were skin and local reactions, sedation, digestive
-
effectivehealthcare.ahrq.gov/sites/default/files/delirium-summary.pdf
September 01, 2019 - the
effect of antipsychotics on cognitive function,
delirium severity, or caregiver burden, or for
sedation … 12 The trials for
prevention of delirium evaluated delirium incidence,
length of hospital stay, sedation … The treatment
trials primarily evaluated hospital length of stay and
sedation effects, with most of … stay
in the hospital, inappropriate continuation of
antipsychotic medication once initiated, and
sedation … insufficient
evidence to determine the effect of haloperidol
versus placebo on delirium severity, sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-250-cannabis-other-plant-based-treatments-evidence-summary.pdf
October 01, 2021 - There may be a large increased risk of dizziness and
sedation and a moderate increased risk of nausea … associated with moderate
improvement in pain severity, no effect on overall function and increased risk of
sedation … [SOE]a
Dizziness
Effect Size (N
Studies)
[SOE]a
Nausea
Effect Size (N
Studies)
[SOE]a
Sedation … the results with recent systematic reviews that used
the same methodology, suggests that the risk of sedation … were found with comparable THC to CBD
ratio oral sprays, with large increased risk of dizziness and sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
October 01, 2021 - There may be a large increased risk of dizziness and
sedation and a moderate increased risk of nausea … associated with moderate
improvement in pain severity, no effect on overall function and increased risk of
sedation … [SOE]a
Dizziness
Effect Size (N
Studies)
[SOE]a
Nausea
Effect Size (N
Studies)
[SOE]a
Sedation … the results with recent systematic reviews that used
the same methodology, suggests that the risk of sedation … were found with comparable THC to CBD
ratio oral sprays, with large increased risk of dizziness and sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-chronic-pain-appendix-f5.xlsx
January 12, 2021 - none in any group
Withdrawals due to adverse events
6 months: 10% (5/49) vs. 23% (12/52) vs. 9% (5/55)
Sedation … NR (assumed 0)
Dizziness: 13.5% (29/215) vs. 9.7% (21/216)
Nausea: 16.7% (36/215) vs. 9.7% (21/216)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-chronic-pain-review-q2-tables-f5.xlsx
March 15, 2021 - none in any group
Withdrawals due to adverse events
6 months: 10% (5/49) vs. 23% (12/52) vs. 9% (5/55)
Sedation … NR (assumed 0)
Dizziness: 13.5% (29/215) vs. 9.7% (21/216)
Nausea: 16.7% (36/215) vs. 9.7% (21/216)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/draft-appendix-pbt-cohort-studies.xlsx
May 11, 2021 - none in any group
Withdrawals due to adverse events
6 months: 10% (5/49) vs. 23% (12/52) vs. 9% (5/55)
Sedation … 1.29 (95% CI 0.75 to 2.21)
Nausea: 16.7% (36/215) vs. 9.7% (21/216), RR 1.72 (95% CI 1.04 to 2.85)
Sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-appendix-f-1_0.xlsx
January 01, 2016 - (etomidate-only) 24 Harms Aspiration ITT Technique/Device ETI: RSI vs. sedation-facilitated No cases … No medication Sedation-facilitated vs. … No medication Sedation-facilitated vs. … Sedation-facilitated RSI vs. … Sedation-facilitated RSI vs.
-
effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-apf2_0.xlsx
January 01, 2018 - SAE SAE Cognitive Effects Cognitive Effects Cognitive Effects Cognitive Effects Nausea Nausea Nausea Sedation … Sedation Sedation Sedation Serotonin Syndrome Serotonin Syndrome Serotonin Syndrome Serotonin Syndrome … , 2009 Fair LBP SNRI Duloxetine 120 mg/d 13 Short 27 112 3 112 Confusional state 0 112 NR 14 112 NR Sedation … Sedation Sedation Sedation Weight Gain Weight Gain Weight Gain
Author, Year Quality Pain Population … Sedation Sedation Sedation
Author, Year Quality Pain Population Drug Class Drug Assessment Time (wk
-
effectivehealthcare.ahrq.gov/products/epilepsy-medicine/research-protocol
July 01, 2010 - Inhibitor: None
Yes
Levetiracetam
Synaptic vesicle release modulation
Partial
Neurological: sedation … Yes
Phenobarbital
Potentiate GABA receptor function
Partial
Tonic-Clonic
Neurological: sedation … No
Tiagabine
Increase GABA availability
Partial
Tonic-Clonic
Neurological: confusion, sedation … channel inhibition
Partial
Tonic-Clonic
Lennox-Gastaut
Neurological: psychomotor slowing, sedation … None
Enzyme Inhibitor: None
No
Zonisamide
Na+ channel inhibition
Partial
Neurological: sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/draft-report-plant-based-treatment.pdf
March 01, 2021 - There was a large increased risk of
dizziness and sedation and a moderate increased risk of nausea ( … dizziness: 6 RCTs, N=866, 30%
vs. 8%, relative risk [RR] 3.57, 95% CI 2.42 to 5.60, I2=0%; sedation: … There may
be a large increased risk of dizziness and sedation and a moderate increased risk of
nausea … The risk of
sedation and dizziness appears similar with cannabis-related products, opioids, and the … Important harms include typical adverse effects such as dizziness,
sedation and nausea, but may also
-
effectivehealthcare.ahrq.gov/get-involved/nominated-topics/pico-1-populations-children-with-infantile-hemangiomas-ihs-interventions-early-referral-comparators-delayed-referral-outcomess-minimization-of-functional-impairment-andor-cosmetic-deformity-pico-2-populations-children-with
November 14, 2013 - long-term cosmetic deformity
Pain and/or bleeding associated with ulceration
Avoidance of unnecessary sedation … corticosteroids
Risks of laser treatment (changes in skin pigmentation, ulceration)
Risks associated with sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
January 01, 2023 - There may be a large increased
risk of dizziness and sedation and a moderate increased risk of nausea … high-THC to CBD) may be associated with small improvement in
pain severity, but with increased risk of sedation … Studies)
[SOE]
Dizziness
Effect Size (N
Studies)
[SOE]
Nausea
Effect Size (N
Studies)
[SOE]
Sedation … Studies)
[SOE]
Dizziness
Effect Size (N
Studies)
[SOE]
Nausea
Effect Size (N
Studies)
[SOE]
Sedation … placebo, these interventions resulted in greater risk of common adverse
events (dizziness, nausea, sedation
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/pbt-lsr-draft-report.pdf
February 04, 2022 - There was a large increased risk of dizziness and sedation and a moderate increased risk of
nausea ( … dizziness: 6 RCTs, N=866, 30% vs. 8%, relative risk [RR] 3.57, 95% CI 2.42 to 5.60,
I2=0%; sedation: … There may
be a large increased risk of dizziness and sedation and a moderate increased risk of
nausea … More patients in the gabapentin group reported sedation (60%) than in the nabilone
20
group … Important harms include typical adverse effects such as dizziness,
sedation and nausea, but may also