-
effectivehealthcare-admin.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1412.pdf
December 01, 2014 - using Sedasys to benzodiazepine/opiate-mediated sedation. … Endoscopist/nurse teams administered both sedation methods. … of propofol for sedation during endoscopies, experts also
commented. … compared with benzodiazepine/opioid
sedation. … An
assessment of computer-assisted personalized
sedation: a sedation delivery system to administer
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1406.pdf
June 01, 2014 - delivered using Sedasys to benzodiazepine/opiate-mediated sedation. … sedation during routine endoscopy procedures. … Endoscopist/nurse
teams administered both sedation methods. … compared with benzodiazepine/opioid sedation. … An assessment of computer-assisted personalized
sedation: a sedation delivery system to administer
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
September 20, 2022 - Drug Assessment Time (Wk) Time Category WAE: n WAE: N SAE: n SAE: N Nausea: n Nausea: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Dry Mouth: n Dry Mouth: N N Randomized Dizziness: … : Specific AE Sedation: n Sedation: N N Randomized Dizziness: n Dizziness: N N Randomized Weight Gain … Randomized Dizziness: n Dizziness: N N Randomized Peripheral Edema: n Peripheral Edema: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Weight Gain: n Weight Gain: N N Randomized
Khasbage
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
September 20, 2022 - Specific AE Cognitive Effects: n Cognitive Effects: N N Randomized Dry Mouth: n Dry Mouth: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Dizziness: n Dizziness: N N Randomized Weight Gain … Randomized Dizziness: n Dizziness: N N Randomized Peripheral Edema: n Peripheral Edema: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Weight Gain: n Weight Gain: N N Randomized
Lee, 2020
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-f2-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
September 20, 2022 - Specific AE Cognitive Effects: n Cognitive Effects: N N Randomized Dry Mouth: n Dry Mouth: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Dizziness: n Dizziness: N N Randomized Weight Gain … Randomized Dizziness: n Dizziness: N N Randomized Peripheral Edema: n Peripheral Edema: N N Randomized Sedation … : Specific AE Sedation: n Sedation: N N Randomized Weight Gain: n Weight Gain: N N Randomized
Khasbage
-
effectivehealthcare-admin.ahrq.gov/products/plant-based-chronic-pain-treatment/draft-report
April 01, 2025 - There may be a large increased risk of dizziness and sedation (SOE: low) and a moderate increased risk … There was a large increased risk of dizziness and sedation, and a moderate increased risk of nausea ( … dizziness: 6 RCTs, N=866, relative risk [RR] 3.57, 95% CI 2.42 to 5.60, I 2 =0%; sedation: 6 RCTs, N= … There was a moderate increase in risk of WAEs, a moderate increase in sedation, and a large increase … −0.78, 95% CI −1.59 to −0.08, I 2 =64%; WAEs: 6 RCTs, N=487, RR 1.92, 95% CI 1.10 to 4.80, I 2 =0%; sedation
-
effectivehealthcare-admin.ahrq.gov/health-topics/anesthesia
Sedation can be used with or without anesthesia. … The type of anesthesia or sedation you get depends on many factors.
-
effectivehealthcare-admin.ahrq.gov/products/migraine-emergency/research
December 01, 2019 - The risk of sedation following administration of metoclopramide or neuroleptic agents was 17 percent. … The most common short-term side effects for triptans were skin reactions, local reactions, and sedation … For patients receiving DHE, the most common side effects were skin and local reactions, sedation, digestive
-
effectivehealthcare-admin.ahrq.gov/products/antipsychotics/research
March 01, 2022 - the effect of antipsychotics on cognitive function, delirium severity, or caregiver burden, or for sedation … functioning, length of stay in hospital, inappropriate continuation of antipsychotic drugs, falls, sedation … We were unable to draw conclusions regarding the effect of antipsychotics on sedation, falls, and delirium … Antipsychotics 0 No evidence Second-Generation Antipsychotics Other Therapies 0 No evidence Sedation … No evidence Second-Generation Antipsychotics Second-Generation Antipsychotics 0 No evidence Sedation
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
October 01, 2021 - There may be a large increased risk of dizziness and
sedation and a moderate increased risk of nausea … associated with moderate
improvement in pain severity, no effect on overall function and increased risk of
sedation … [SOE]a
Dizziness
Effect Size (N
Studies)
[SOE]a
Nausea
Effect Size (N
Studies)
[SOE]a
Sedation … the results with recent systematic reviews that used
the same methodology, suggests that the risk of sedation … were found with comparable THC to CBD
ratio oral sprays, with large increased risk of dizziness and sedation
-
effectivehealthcare-admin.ahrq.gov/products/plant-based-chronic-pain-treatment/living-review
March 01, 2025 - There may be a large increased risk of dizziness and sedation (SOE: low) and a moderate increased risk … There was a large increased risk of dizziness and sedation, and a moderate increased risk of nausea ( … dizziness: 6 RCTs, N=866, relative risk [RR] 3.57, 95% CI 2.42 to 5.60, I 2 =0%; sedation: 6 RCTs, N= … There was a moderate increase in risk of WAEs, a moderate increase in sedation, and a large increase … The exception was high-THC products and increased risk of sedation, which was imprecise and no longer
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-appendix-f-1_0.xlsx
January 01, 2016 - (etomidate-only) 24 Harms Aspiration ITT Technique/Device ETI: RSI vs. sedation-facilitated No cases … No medication Sedation-facilitated vs. … No medication Sedation-facilitated vs. … Sedation-facilitated RSI vs. … Sedation-facilitated RSI vs.
-
effectivehealthcare-admin.ahrq.gov/products/epilepsy-medicine/research-protocol
December 01, 2019 - Expired 9/26/09
Gabapentin
GABA analogue for alpha-2 delta subunit
Partial
Neurological: sedation … Phenobarbital
Potentiate GABA receptor function
Partial
Tonic-Clonic
Neurological: sedation … None
No
Primidone
Inhibition of neuronal firing
Partial
Tonic-Clonic
Neurological: sedation … Tiagabine
Increase GABA availability
Partial
Tonic-Clonic
Neurological: confusion, sedation … Enzyme Inhibitor: None
No
Zonisamide
Na+ channel inhibition
Partial
Neurological: sedation
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/nonopioid-chronic-pain-apf2_0.xlsx
January 01, 2018 - SAE SAE Cognitive Effects Cognitive Effects Cognitive Effects Cognitive Effects Nausea Nausea Nausea Sedation … Sedation Sedation Sedation Serotonin Syndrome Serotonin Syndrome Serotonin Syndrome Serotonin Syndrome … , 2009 Fair LBP SNRI Duloxetine 120 mg/d 13 Short 27 112 3 112 Confusional state 0 112 NR 14 112 NR Sedation … Sedation Sedation Sedation Weight Gain Weight Gain Weight Gain
Author, Year Quality Pain Population … Sedation Sedation Sedation
Author, Year Quality Pain Population Drug Class Drug Assessment Time (wk
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-executive-summary-2023-update.pdf
January 01, 2023 - There may be a large increased
risk of dizziness and sedation and a moderate increased risk of nausea … high-THC to CBD) may be associated with small improvement in
pain severity, but with increased risk of sedation … Studies)
[SOE]
Dizziness
Effect Size (N
Studies)
[SOE]
Nausea
Effect Size (N
Studies)
[SOE]
Sedation … Studies)
[SOE]
Dizziness
Effect Size (N
Studies)
[SOE]
Nausea
Effect Size (N
Studies)
[SOE]
Sedation … placebo, these interventions resulted in greater risk of common adverse
events (dizziness, nausea, sedation
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - Potentiate
GABA
receptor
function
Absence
Atypical
Absence
Myoclonic
Neurological: ataxia,
sedation … and increase
GABA
availability
Partial
Lennox-
Gastaut
Neurological: insomnia,
dizziness, sedation … Tonic-
Clonic
Atypical
Absence
Myoclonic
Lennox-
Gastaut
Neurological: dizziness,
diplopia, sedation … Yes
Phenobarbital Potentiate
GABA
receptor
function
Partial
Tonic-
Clonic
Neurological: sedation … No
Tiagabine Increase
GABA
availability
Partial
Tonic-
Clonic
Neurological: confusion,
sedation
-
effectivehealthcare-admin.ahrq.gov/products/mental-health-pregnancy/research
March 01, 2022 - Brexanolone probably improves depressive symptoms; it may increase the risk of sedation or somnolence … Brexanolone for depression onset in the third trimester or in the postpartum period may increase the risk of sedation
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
May 12, 2015 - medications, such as Parkinsonism, akathisia, dystonia, and tardive dyskinesia), prolactin elevation,
sedation … medication (e.g., diabetes mellitus, extrapyramidal symptoms / tardive dyskinesia,
prolactin elevation, sedation
-
effectivehealthcare-admin.ahrq.gov/news/best-of-2022
February 01, 2023 - may be associated with short-term improvements in chronic pain and increased risk for dizziness and sedation
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-evidence-summary-2022-update_0.pdf
January 01, 2022 - There may be a large increased risk of dizziness and sedation and a moderate
increased risk of nausea … high-THC to CBD) may be associated with moderate
improvement in pain severity, but with increased risk of sedation … Studies)
[SOE]
Dizziness
Effect Size (N
Studies)
[SOE]
Nausea
Effect Size (N
Studies)
[SOE]
Sedation … the results with recent systematic reviews
that used the same methodology, suggests that the risk of sedation … placebo, these interventions resulted in greater risk of common adverse events (dizziness,
nausea, sedation