-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-outcomes_disposition-comments.pdf
January 15, 2015 - risk population at risk for medical problems. … However, the epidemiological
characteristics and risk factors for suicide are very different
from those … Clinicians
can sometimes identify modifiable risks for suicide, with the
presumption that intervention … can reduce suicide risk. … (One might argue that
more frequent screenings for cardiovascular or diabetic risk
may be needed but
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-protocol-update-2023.pdf
January 01, 2023 - of bias using the Cochrane risk-of-bias tool for randomized trials
(RoB 2),16 and calculating standardized … Assessment of Methodological Risk of Bias of Individual Studies:
The EPC will conduct a risk of bias … RoB 2: a revised tool for assessing risk of bias in
randomised trials. BMJ. 2019;366:l4898. … Results for suicide- or self-directed violence-related outcomes
2. … RoB 2, A REVISED TOOL FOR ASSESSING RISK OF BIAS IN RANDOMISED
TRIALS: ASSESSMENT ELEMENTS
1.1) Was
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - The risk of
being seizure free for either 6–12 or 24 months
was significantly lower for newer antiepileptic … ,
HLA-B 1502 genotyping
could be used as a screening
tool and use of tegretol
should be avoided. … Suicidal risk and suicide attempts in
people treated with antiepileptic drugs for
epilepsy. … , suicide
attempts
Antiepileptic drugs probably do not have an impact on
suicidality
Misra, 201219 … The risk of being seizure
free for either 6–12 or 24 months was significantly lower
for newer antiepileptic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - The risk of
being seizure free for either 6–12 or 24 months
was significantly lower for newer antiepileptic … ,
HLA-B 1502 genotyping
could be used as a screening
tool and use of tegretol
should be avoided. … Suicidal risk and suicide attempts in
people treated with antiepileptic drugs for
epilepsy. … , suicide
attempts
Antiepileptic drugs probably do not have an impact on
suicidality
Misra, 201219 … The risk of being seizure
free for either 6–12 or 24 months was significantly lower
for newer antiepileptic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
October 24, 2019 - Other outcomes – Anxiety, anger, depression, functioning, quality of life, sleep,
substance use, suicide … Assessment of Methodological Risk of Bias of Individual Studies:
Risk of bias (ROB) assessment will … Suicide- and self-directed violence-related inclusion/exclusion criteria
t. … Results for all suicide- or self-directed violence-related outcomes
t. … COMPARATIVE EFFECTIVENESS REVIEW No. 207 RISK OF BIAS
ASSESSMENT ELEMENTS
a.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-opioid-stewardship-protocol.pdf
July 01, 2023 - However, opioids also carry well known risks,
including for overdose, misuse, and opioid use disorder … Risk of Bias (Quality) Assessment
For studies that address Review Question 5 about the effectiveness … of PSPs, the primary
reviewer will use the Cochrane Collaboration’s tool for assessing the risk of … The Cochrane Collaboration's tool for assessing risk of bias in
randomised trials. … ROBINS-I: a tool for assessing risk of bias in non-randomised
studies of interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1412.pdf
December 01, 2014 - Effectiveness
Research, AHRQ is interested in innovations in drugs and biologics, medical devices, screening … , treatments, screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations … treating depressed patients at high risk of suicide, are also registered.36,37
Manufacturer and regulatory … for suicide. … Pilot studies of ketamine intrigue
scientists, but risks of this anesthetic limit its
clinical use
-
effectivehealthcare.ahrq.gov/sites/default/files/depression_hi_impact.pdf
October 01, 2014 - This delay can increase suicide risk and mortality. … HDRS = 15.4 [+/-2.8]).”
7
According to
Medtronic, patients who undergo DBS to treat MDD would face risks … offer this intervention because of high costs, invasiveness,
infrastructure requirements, potential risks … This delay can result in increased suicide risk and mortality.
23
Therefore, an unmet need exists for … No citizen-soldiers left behind: six initiatives to
counteract veterans' PTSD, depression and
suicides
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
December 04, 2015 - Lastly, differences in some harms
outcomes (e.g., weight gain and metabolic risks) have been shown to … Suicide-related ideations or behaviors, or death by suicide*
•! … We will track the screening and selection results in
EndNote.
C.!Study!Selection! … The risk of bias for all other studies will be
rated as medium. … For binary outcomes, we will use a relative risk (RR) of 0.75 and 1.25 to represent
!
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pqmp-disposition-comments.pdf
April 07, 2025 - Thank you for this comment – we added:
“Additional barriers include potential financial risks or
drivers … are “fit for purpose”:
surveillance; quality improvement; financial risk—
“accountable care”. … screenings done at school, by school nurses, under
Thank you for your comment. … guidelines for pediatric auditory, visual, and
developmental screenings), the need for interventions … of systemic flexibility impact timely
intervention for at-risk children.
-
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-32-pharm-non-pharm-ptsd.pdf
May 14, 2019 - Since many of the PTSD
studies have already been rated for quality and risk of bias in
prior reviews … and for Risk
of Bias that could be filled in and marked as taken from a prior
review. … Future efforts on
expanding this data set may include risk of
bias assessments. … This is different from an initial screening for study
eligibility in which individuals would be excluded … While screening
studies for this project, we noted any studies
that were excluded only for this reason
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
April 01, 2013 - For pharmacological treatments, very few studies
reported any information about mortality, suicide, … The psychological
risks of Vietnam for U.S. veterans: a revisit with new data and
methods. … Post-traumatic stress disorder and suicide
risk: a systematic review. … Symptom reduction and
suicide risk in patients treated with placebo in antidepressant
clinical trials … Symptom reduction and
suicide risk among patients treated with placebo in antipsychotic
clinical trials
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
April 01, 2022 - increased likelihood of experiencing a pain
response (>30% reduction in pain intensity, 60% vs. 35%, relative … of suicide (fatal or nonfatal) but similar decreased risk of overdose events
when compared with dose … Opioid Risk Screening in an Oncology
Palliative Medicine Clinic. … suicide deaths in US veterans:
observational evaluation. … Validation of the OWLS, a Screening Tool
for Measuring Prescription Opioid Use
Disorder in Primary
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2023.pdf
January 01, 2023 - Who: Mental health conditions (including deaths from suicide and
overdose/poisoning related to substance … International Conference on Pharmacoepidemiology and Therapeutic Risk Management. … Making Healthcare Safer IV: Protocols for High-Risk Drugs: Reducing Adverse Drug Events Related to
Anticoagulants … U18 HS028736-02 Improving Primary Care Understanding of Resources and Screening for Urinary
Incontinence … The Improved Systematic Review Data Repository Plus (SRDR+): A Free, “FHIR-ed up” Tool for
Screening
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
March 28, 2019 - No studies used PHQ-9 for depression
screening/diagnosis and no exclusions
were made based on this … The Cochrane Risk of Bias tool was
used to assess the risk of bias for each
included RCT. … Hip fracture and suicide do not
seem to go together. … suicide
risk. … For example, depression
in an of itself in older adults a risk for falls.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Effectiveness Research, AHRQ is interested in innovations
in drugs and biologics, medical devices, screening … , treatments, screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations … immediate
intervention is vital to reduce the risk of serious harm to patients.1,2 An unmet need exists … Multiple experts also
opined that direct cost to patients, unresolved dosing protocols, and safety risks … Pilot studies of ketamine intrigue
scientists, but risks of this anesthetic limit its
clinical use
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1312.pdf
October 01, 2014 - , a subcategory of MDD, is associated with a higher risk of hospitalization,
suicide attempts, and … completed suicides than nonpsychotic MDD. … , especially considering the debilitating nature and risk of suicide attempts
and completed suicides … This delay can
increase suicide risk and mortality. … risk of hospitalization, suicide attempts, and suicides than nonpsychotic
MDD—are associated with
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-adhd-prescription-rapid-research.pdf
July 01, 2025 - Suicide attempts accounted for 74.1 percent of all non-accidental oral exposures. … is associated with increased risk for substance use disorders in adulthood. … use
disorder) 6.2%;
prevalence in those
without suicide ideation
1.7%. … Given by Friend class
had the lowest
prevalence of positive
screening scores on all
mental health … .001) and
perceptions of not having to worry
about potential negative side effects
and other health risks
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol-2021_0.pdf
January 01, 2021 - Assessment of Methodological Risk of Bias of Individual Studies:
The EPC will conduct a risk of bias … RoB 2: a revised tool for assessing risk of bias in
randomised trials. BMJ. 2019;366:l4898. … Suicide- and self-directed violence-related inclusion/exclusion criteria
t. … Results for all suicide- or self-directed violence-related outcomes
t. … RoB 2, A REVISED TOOL FOR ASSESSING RISK OF BIAS IN RANDOMISED
TRIALS: ASSESSMENT ELEMENTS
1.1) Was
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd4-final-protocol.pdf
October 01, 2022 - Assessment of Methodological Risk of Bias of Individual Studies:
The EPC will conduct a risk of bias … RoB 2: a revised tool for assessing risk of bias in
randomised trials. BMJ. 2019;366:l4898.
14. … Suicide- and self-directed violence-related inclusion/exclusion criteria
t. … Results for all suicide- or self-directed violence-related outcomes
t. … RoB 2, A REVISED TOOL FOR ASSESSING RISK OF BIAS IN RANDOMISED
TRIALS: ASSESSMENT ELEMENTS
1.1) Was