-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/anxiety-children_research-protocol.pdf
September 12, 2016 - Studies
included by either reviewer will be retrieved for full-text screening. … Assessment of Methodological Risk of Bias of Individual Studies
We will evaluate the risk of bias of … For
RCTs, we plan to apply the Cochrane Collaboration’s Risk of Bias tool to assess
sequence generation … the methodological
limitations of the studies (i.e., risk of bias); precision (based on the size of … Clinical response and risk for reported
suicidal ideation and suicide attempts in pediatric antidepressant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - behaviors, and death by suicide. … disorder, what is the comparative effectiveness and risks of
FGAs vs. … behaviors, and death by suicide … The risk of bias for all other studies will be rated as
unclear. … Data Synthesis
For each study, we will analyze comparisons between dichotomous outcomes by
using risk
-
effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_2012-12-10.pdf
January 01, 2012 - PMD is a subcategory of MDD and is associated with a higher risk of
hospitalization, suicide attempts … , and suicides than nonpsychotic MDD. … This
delay can increase suicide risk and mortality. … , suicide attempts, and suicides than
nonpsychotic MDD—are associated with unwanted side effects, extensive … Pilot studies of ketamine intrigue
scientists, but risks of this anesthetic limit its
clinical use
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1306.pdf
October 01, 2014 - that yield rapid response in severely depressed patients at risk
of suicide are critically needed. … , a subcategory of MDD, is associated with a higher risk of hospitalization,
suicide attempts, and … , especially considering the debilitating nature and risk of suicide attempts
and completed suicides … This
delay can increase suicide risk and mortality. … disorder (MDD) with a higher risk of hospitalization, suicide attempts, and
suicides than nonpsychotic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children_executive.pdf
February 01, 2012 - • Suicide-related behaviors or death by suicide.
• Medication adherence and persistence. … SGAs and placebo did not significantly
differ for suicide-related behaviors (moderate strength
of evidence … Suicide-related SGA vs. placebo (7 RCTs) Moderate No significant difference for suicide-related
behaviors … As would be expected, SGAs
consistently resulted in greater symptom improvement
and greater risk for … Treatment benefits and risks were examined most
frequently for schizophrenia; the evidence for
conditions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-200-post-acs-depression.pdf
November 01, 2017 - Review
Patients who are diagnosed with acute
coronary syndrome (ACS) are at increased
risk for mental … Post-ACS Screening Strategies
A number of screening tools for depression
have been developed. … patients
Instruments
Screening tools
for depression
Diagnostic accuracy
Sensitivity, specificity … [PHQ])
may be almost as accurate for diagnostic screening as
using the full instrument. … This suggests that other screening instruments
that may be more feasible for use in general medical
-
effectivehealthcare.ahrq.gov/sites/default/files/05_depression_potential_high_impact_june_2012.pdf
January 01, 2012 - of hospitalization, suicide attempts, and suicides than nonpsychotic MDD. … This
delay can increase suicide risk and mortality. … depressive disorder (MDD) with a higher risk of hospitalization, suicide attempts, and suicides than … = 15.4 [+/-2.8]).”
21
According to Medtronic, patients who
undergo DBS to treat MDD would face risks … Pilot studies of ketamine intrigue
scientists, but risks of this anesthetic limit its
clinical use
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_disposition-comments.pdf
July 08, 2014 - implication of these findings is that antenatal depression
should be identified through universal screening … Decrease in suicide as a benefit. As written,
sounds like maternal suicide is a benefit. … of these
three risks. … risks of underlying
depression. … Added definition for RRR: relative risk reduction (reported in the
study rather than relative risk)
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
January 01, 2018 - suicide,
suicide ideations, or suicide behaviors in short-term
studies.
11
Table B. … placebo
Effectiveness
Outcomes
Short-term suicide attempts/
suicides (RCTs: 7, 1463)
Attempts: 2 … of relative risks ranged between 0.02 to 5.0,
to 0.06 to 48.1).
13
Bipolar Disorder
Of 19 studies … Risks for somnolence and EPS symptoms
may be of little or no difference for low- versus high-
dose risperidone … Guidelines for
screening and monitoring of cardiometabolic risk in schizophrenia:
systematic evaluation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - Timing: See KQ1 above
Settings: See KQ1 above
Question 4: Do the effectiveness and risks of first … be rated as high risk of bias. … The overall risk of bias will be
considered low only if all components are rated as having a low risk … The risk of bias for
all other studies will be rated as unclear. … Data Synthesis
For each study, we will analyze comparisons between dichotomous outcomes using risk
-
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
November 03, 2020 - of opioid prescribing, including risks for
overdose, suicide, and death. … Findings p. 38 – Was suicide included? … There is a
growing literature on opioids as a risk factors for
suicide yet none is mentioned. … of harms (e.g., suicide). … However, given the lack of focus on
screening for and diagnosing OUD in older
adults, the previously
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
September 30, 2015 - body mass index; CI = confidence interval; COWS = Clinical Opiate Withdrawal Score; DAST = Drug Abuse Screening … care provider; RCT = randomized controlled trial; RMDQ = Roland Morris Disability Questionnaire; RR = relative … CI 2.05 to 2.96, p<0.001
Anxiety: 505/22097 vs. 6174/152194; aIRR 1.79, 95% CI 1.48 to 2.15, p<0.001
Suicide … D
Any opioid-related event: 5.3% vs. 6.1% vs. 3.4% vs. 3.6%, p<0.0001
Suicide (fatal or nonfatal): 1.0% … of suicide: aHR 3.63 (95% CI 1.42 to 9.25) vs. aHR 4.47 (95% CI 1.68 to 11.88) vs. aHR 1.29 (95% CI
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-treatment-ssri_research-protocol.pdf
June 15, 2010 - Harms associated with any
of these interventions are evaluated in KQ2 and can include suicide, sexual … We have selected the Newcastle Ottawa Quality Assessment Tool13 to assess risk of bias
for observational … Studies that pass the
first screening for fatal flaws will be classified into high or low risk of bias … and Laird random-effects model to generate pooled measures
of treatment effect (i.e., estimates of relative … Screening for child and adolescent depression
in primary care settings: a systematic evidence review
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
January 27, 2012 - or who prefer disulfiram and understand the relative risks
of taking the drug; and (3) to have specialist … the risk of bias for
each study. … between acamprosate and naltrexone, whereas the risks
of headache and vomiting were higher for those … Behavioral counseling after
screening for alcohol misuse in primary care: a systematic review
and … Screening, Behavioral
Counseling, and Referral in Primary Care To Reduce Alcohol
Misuse.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-6-protocol.pdf
December 07, 2024 - of bias using the Cochrane risk-of-bias tool for randomized trials
(RoB 2),18 and calculating standardized … Assessment of Methodological Risk of Bias of Individual Studies:
The EPC will conduct a risk of bias … RoB 2: a revised tool for assessing risk of bias in
randomised trials. BMJ. 2019;366:l4898. … Suicide Deaths Detail
16. Suicide Deaths Numerator
17. Suicide Deaths Denominator
18. … Continuous Outcomes
Suicide Dichotomous Outcomes
Other Outcomes
Harms
Unpublished Data
Risk of
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1406.pdf
June 01, 2014 - In these cases,
patients are exposed to prolonged and increased risk of suicide and death. … mixed clinical trial results, as well as safety risks of using a
controlled substance … treating depressed patients at high risk of suicide are also registered.36,37
Manufacturer and regulatory … , as
well as the risk of anticholinergic effects noted for scopolamine’s approved indications. … for suicide.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_executive.pdf
April 01, 2013 - and tobacco use,51 screening for diabetes
in patients with elevated blood pressure,52 and lipid
screening … These guidelines for the general population should
then be modified to consider the special risks for … CVD
risk screening and followup.57 Studies show screening
rates ranging from about 10 to 26 percent … and mental
health care as effective for CVD screening. … Screening for High
Blood Pressure: U.S.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioid-treatments-chronic-pain-protocol.pdf
December 19, 2018 - addressed the risks and benefits of opioids for chronic pain, dosing strategies, and risk
assessment … long-term opioid therapy only when benefits are
likely to exceed risks; use risk mitigation strategies … strategies, including (1) opioid management plans,
(2) patient education, (3) urine drug screening, … mitigation
strategies,
including (1)
opioid
management plans,
(2) patient
education, (3)
urine drug
screening … The effectiveness and risks of long-term opioid therapy for
chronic pain: a systematic review for a
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_executive.pdf
April 28, 2010 - , cardiomyopathy,
anemia, osteoporosis, cognitive
impairment, depression, insomnia,
anxiety, and suicide … Screenings to identify subjects
for the included studies were often extensive, multistep
processes … Brief physician advice
for high-risk drinking among young adults. … Brief patient-centered
clinician-delivered counseling for high-risk drinking: 4-year
results. … Brief physician
and nurse practitioner-delivered counseling for high-risk drinking.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
April 01, 2020 - review addressed the risks and benefits of opioids
for chronic pain, dosing strategies, and risk … suicide/self-harm (SOE: low). … ;
SOAPP = Screening and Opioid Assessment for Patients with Pain; SOAPP-R = Screening and Opioid Assessment … assessment instruments
other than the Opioid Risk Tool (ORT) and
Screening and Opioid Assessment for … The effectiveness
and risks of long-term opioid therapy for chronic pain:
a systematic review for a