-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-protocol-amendment.pdf
March 22, 2023 - effect of atypical
antipsychotics
- Allergic reaction
- Sleep disruption, fatigue
- Sudden death
- Suicide … Each study will
be dual reviewed for risk of bias by two team members. … points on a 0 to 100-point scale
• SMD >0.8
• RR/OR ≥2.0
MD = mean difference; OR = odds ratio; RR = relative … The social ecology of community and neighborhood and risk for antisocial
behavior. … training" or "aggression questionnaire" or "aggression
replacement training" or "antisocial process screening
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
April 10, 2020 - might be warranted in presenting the harms
associated with SSRIs, given evidence regarding higher risk … of withdrawals with SSRIs as a class for adolescents with depression
(risk difference, 26/1,000; 95% … as received, we
generally did not downgrade studies for
poor adherence in the risk of bias
assessment … We did, however, mark
down studies with high and/or differential
attrition for risk of bias. … Participant inclusion was
based on screening questionnaire
cutpoints rather than an MDD diagnosis.
-
effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
October 01, 2007 - Lippincott Williams & Wilkins S59
leagues12 used 50-state Medicaid data in a case–control study
of risks … of suicide attempts and suicide deaths in severely
depressed children and adults; in children and adolescents … with a
2-by-2 framework familiar from the medical screening liter-
ature. … Lifetime prevalence,
demographic risk factors, and diagnostic validity of nonaffective psy-
chosis as … Antidepressant drug therapy and
suicide in severely depressed children and adults: a case-control study
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cultural-competence_research-protocol.pdf
July 09, 2014 - Only systematic reviews that assess included study risk of
bias will be assessed for review quality. … For RCTs, questionnaires developed from the Cochrane Risk of Bias tool will be
used. … 5.1.0.7
We developed an instrument for assessing risk of bias for observational studies based
on … in assessing risk of bias for this topic, including participant selection;
attrition, ascertainment … Two investigators will independently assess risk of bias for all included studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
March 01, 2022 - • Studies on the acute treatment of migraine that
compare relative risks of medication overuse … Trials Standardized Data
Repository (PTSD-Repository) with data on PTSD and
mental health, including suicide-related … studies that looked at prior or early
postoperative opioid use found mostly strong
associations (e.g., relative … • Studies on the effects of risk mitigation strategies
(use of naloxone, urine drug screening, prescription … • Screening rates are higher with patient navigation
for colorectal, breast, and cervical cancer;
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
April 02, 2013 - Reasons for high
risk of bias ratings are presented in the
appendix of the report. … Our criteria for rating the risk of bias are
based on established guidance by the
AHRQ Evidence-based … suicide or by medication toxicity, for
example) would be a key AE to monitor. … criterion would be relevant only
perhaps for universal screening interventions. … Universal intervention may be most useful as a way of identifying those at
greatest risk (screening)
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-prevention_executive.pdf
June 01, 2013 - , relative risk,
and absolute risk differences (ARDs). … Using Meta-Analyst and STATA® software, we calculated
the relative risk and absolute risk difference … We evaluated the strength of the association a
priori, defining a large effect as having relative risk … relative risk that was
significant but <2. … Clinical response and risk
for reported suicidal ideation and suicide attempts in pediatric
antidepressant
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
April 03, 2014 - dizziness, nausea, fatigue, dry mouth, weight gain,
difficulty concentrating, hypertension, thoughts of suicide … Citations
determined potentially eligible by either investigator will undergo full text screening for … For randomized clinical trials (RCTs), we will assess the risk of bias using a modified
Cochrane Risk … Similar to risk of bias for RCTs, the overall summary risk of bias will
be weighted towards low for … good studies (low risk of bias) for high strength of evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-203-adhd-disposition-comments.pdf
January 01, 2018 - From
screening it was excluded for
being a guideline. … for
exclusion), and (8) that passed full-text
screening and were included in the
review. … For example, health risk
behaviors such as substance abuse, binge eating, etc. … No other
identified risks found (would be good to put a statistical
estimate for how high the risk, … e.g., of suicide or sudden death,
could be and still not be detected).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment-update_research-protocol.pdf
December 31, 2017 - for exposure to trauma and, thus, at
elevated risk for a PTSD diagnosis. … victims of particular types of
trauma or to determine comparative risks of adverse effects. … PTSD have a very high risk of selection bias and
confounding. … The
psychological risks of Vietnam for U.S. veterans: a revisit with new data and methods. … ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating_executive.pdf
December 01, 2015 - ).94 Finally, one study
(of attempted suicides)93 and a review article of three
studies (of suicides … )92 found no evidence of increased risk
of suicide among BED patients 5 years after treatment
(moderate … of suicide among BED patients 5
years after treatment (moderate strength of evidence for no
effect … at-risk for obesity. … A comprehensive meta-analysis
of the risk of suicide in eating disorders.
-
effectivehealthcare.ahrq.gov/sites/default/files/depression-horizon-scan-high-impact-1512.pdf
December 01, 2015 - Effectiveness Research, AHRQ is interested in innovations
in drugs and biologics, medical devices, screening … , treatments, screening and diagnostics, therapeutics, surgery, programs, and
care delivery innovations … Although intravenous ketamine has
known safety risks and might require increased infrastructure or … In
contrast, several experts predicted that ketamine’s unclear adverse event profiles and abuse risk … Pilot studies of ketamine intrigue
scientists, but risks of this anesthetic limit its
clinical use
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/alcohol-pharma-final-protocol.pdf
January 01, 2023 - those
used to treat alcohol withdrawal.40 They referenced a growing body of research to support
basic screening … whom acamprosate and oral naltrexone are not suitable
or prefer disulfiram and understand the relative … risks of taking the drug; and (3) to have
specialist and competent staff administer pharmacological … Two independent reviewers will assess risk of bias for each study. … For binary outcomes (e.g.,
adverse events), we will calculate risk differences between groups or risk
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
August 01, 2012 - behaviors, and death by suicide … ,
what are the comparative effectiveness and risks
of FGAs versus SGAs in subgroups defined by the … The most common reasons
for trials to be assessed as having high risk of bias were
lack of blinding … Further, all of the included trials had an
unclear risk of bias (n = 78, 63 percent) or high risk of … , influence the occurrence of serious AEs,
which would help estimate possible risks in specific patient
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-heart-disease-children_research.pdf
January 01, 2023 - Confounders
To control for potential differences in the risk of coronary heart disease among those … of the above variables with risk of each endpoint (i.e., a separate CRS for MI, SCD,
or combined MI/ … In analyses adjusted for matching variables
plus the cardiovascular risk score, rate ratios of MI or … We adjusted for a large number of
established and potential cardiovascular risk factors. … and
adolescents between the ages of 3 and 20 years (hazard ratio=1.2; 95% CI 1.0-1.4)11 and that
risks
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/strategies-integrating-behavioral-health-protocol.pdf
August 04, 2022 - As such, we will assess risk of bias for Questions 2 and 5a. … Predefined criteria will be used to assess the risk of bias for each individual
included study, using … Reviews.43
Studies will be rated as “low risk of bias,” “medium risk of bias,” or “high risk of bias … Each
study evaluated will be independently reviewed for risk of bias by two team members. … Similar to assessment of risk of bias for
individual studies, the strength of evidence (SOE) for each
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery_research.pdf
June 01, 2010 - exempt from Federal regulations because the research activities were considered to be of
minimal risk … members who met any of these inclusion criteria during 2002
through 2005: (1) completed a health risk … symptoms and others documenting
development of new depressive symptoms and an increased incidence of suicide … Additionally, the possibility of eliminating medications and the resulting cost
reductions and reduction in risks … Screening characteristics of the selected propensity model in the validation sample
Percentile of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
January 01, 2011 - The checklist for risk factor studies had 6
criteria for external validity, 13 criteria for internal … Suicide as an
outcome for medical disorders. Medicine
(Baltimore) 1994 Nov;73(6):281-296.
64. … ” and for risk assessment
guidance. … Define risk factor or list risk factors for
which quality assessment would be the same. … Define risk factor or list risk factors for which quality assessment would be the same:
Source to
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-228-nonopioid-pharm-chronic-pain-comments.pdf
April 16, 2020 - were a lack of studies examining
co-prescription of neuropathic agents and the synergistic effects on risk … evidence on long-
term effectiveness [of opioids] is very limited and there is evidence of
increased risk … ASRA recognizes that all drugs – opioid and
nonopioid – carry risks. … an opioid prescription, who are at risk for
development of an opioid use disorder, or who have other … stories of thousands who felt they
had no other choice to escape their debilitating pain, so they chose suicide
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
March 24, 2017 - We used AHRQ EPC methods for risk of bias
assessment; EQUATOR provides guideline for
reporting studies … themselves
because of physical weakness, sensory losses, risks
of falling, depression and dementia … There are minimal risks
of exercise and cognitive training. … In
addition, it would reduce the risks of cancer and
chronic kidney disease. … stricken, physically and cognitively impaired
with a high rate of dependence, criminal offenses and
suicide