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1. Schizophrenia | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/health-topics/schizophrenia/

2. Treatments for Adults with Schizophrenia | Effective Health Care Program
   effectivehealthcare.ahrq.gov/products/schizophrenia-adult
   August 17, 2016 - Treatments for Adults with Schizophrenia Timeline April 26, 2016 Topic Initiated … August 17, 2016 Research Protocol Treatments for Adults with Schizophrenia … October 26, 2017 Systematic Review Treatment for Adults With Schizophrenia

3. Treatment for Adults With Schizophrenia | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/schizophrenia-adult/research-2017
   October 26, 2017 - Suggestion Aug. 17, 2016 Research Protocol Oct. 26, 2017 Systematic Review Treatment for Adults With Schizophrenia … Purpose of Review To evaluate treatments for schizophrenia. … This systematic review (SR) provides evidence on pharmacological and psychosocial treatments for schizophrenia … antipsychotic (FGA) and studies comparing psychosocial interventions with usual care in adults with schizophrenia … Treatments for Schizophrenia in Adults: A Systematic Review.

4. Treatments for Schizophrenia in Adults: A Systematic (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
   January 01, 2017 - The course of schizophrenia varies. … Clozapine versus other atypical antipsychotics for schizophrenia. … Family intervention for schizophrenia. … Social skills programmes for schizophrenia. … Treatments for Schizophrenia in Adults: A Systematic Review.

5. Treatments for Adults with Schizophrenia: A Systematic Review (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
   September 23, 2016 - Definition and description of schizophrenia in the DSM-5. … Schizophrenia: a concise overview of incidence, prevalence, and mortality. … Work Group on Schizophrenia; Lehman AF, Lieberman JA, Dixon LB, et al. … Diseases and Conditions: Schizophrenia. http://www.mayoclinic.org/diseases- conditions/schizophrenia/ … Schizophrenia. http://www.nimh.nih.gov/health/topics/schizophrenia/index.shtml.

6. Treatments for Adults with Schizophrenia | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/schizophrenia-adult/research-protocol/

7. TND-0775-150722 (pdf file)
   effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0775-150722.pdf
   May 12, 2015 - Treatments for Adults with Schizophrenia … Staff-Generated PICOs Key Question #1 Population(s): Male and female adults with schizophrenia or … Considerations § Schizophrenia is a brain disorder in which people interpret reality abnormally; it … Common non- pharmacological interventions for adult schizophrenia include psychotherapy, multicomponent … , schizophrenia-related psychoses, or bipolar disorder, with a focus on core illness symptoms, functional

8. Comparative Effectiveness of First and Second Generation Antipsychotics in the Adult Population | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/antipsychotics-adults/research-protocol
   December 01, 2010 - KQ2: For adults (aged 18 to 64 years) with Schizophrenia, Schizophrenia-related psychoses, or bipolar … KQ 3: For adults (aged 18 to 64 years) with Schizophrenia, Schizophrenia-related psychoses, or bipolar … KQ 4: For adults (aged 18 to 64 years) with Schizophrenia, Schizophrenia-related psychoses, or bipolar … KQ 5: For adults (aged 18 to 64 years) with Schizophrenia, Schizophrenia-related psychoses, or bipolar … Schizophrenia, Catatonic/ 3. Schizophrenia, Disorganized/ 4. Schizophrenia, Paranoid/ 5.

9. Comparative Effectiveness of First and Second Generation Antipsychotics in the Pediatric and Young Adult Populations | Effective Health Care (EHC) Program
   effectivehealthcare.ahrq.gov/products/antipsychotics-children/research-protocol
   June 04, 2010 - For example, on-label indications are available for treatment of childhood schizophrenia and bipolar … and schizophrenia-related psychoses.” … and schizophrenia-related psychoses, including schizoaffective disorder and drug-induced psychosis … / schizophrenia-related psychosis or behavioral issues Interventions: See KQ1 above Comparators: … Schizophrenia/ Schizophrenia, Catatonic/ Schizophrenia, Disorganized/ Schizophrenia, Paranoid/

10. Topic Suggestion Description | Effective Health Care Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-efficacy-and-comparative-effectiveness-of-pharmacological-and-nonpharmacological-treatments-for-adults-with-schizophrenia-what-are-the-harms-from-pharmacological-and-nonpharmacological-treatments-for-adults-with-s
    November 17, 2014 - Schizophrenia affects approximately 7 of every 1000 individuals in the U.S. population McGrath et al. … The incidence of schizophrenia peaks in early adulthood Messias et al. … Rates of suicide are also elevated in individuals with schizophrenia with a lifetime risk of about 5 … as compared to a demographically adjusted population without schizophrenia Fitch et al. … Treatments for Adults with Schizophrenia

11. Antipsychotics-Children Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
    June 04, 2010 - For example, on-label indications are available for treatment of childhood schizophrenia and bipolar … and schizophrenia-related psychoses … Schizophrenia, Childhood/ 6. Mental Retardation/ 7. Movement Disorders/ 8. … Schizophrenia/ 16. Schizophrenia, Catatonic/ 17. Schizophrenia, Disorganized/ 18. … Schizophrenia, Paranoid/ 19. Psychotic Disorders/ 20. first episode schizophrenia.tw. 21.

12. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
    December 01, 2010 - Background and Objectives for the Systematic Review Schizophrenia and Related Psychoses Schizophrenia … Population: Adults (aged 18 to 64 years) with Schizophrenia, Schizophrenia- related psychoses, or bipolar … KQ2: For adults (aged 18 to 64 years) with Schizophrenia, Schizophrenia-related psychoses, or bipolar … KQ 3: For adults (aged 18 to 64 years) with Schizophrenia, Schizophrenia-related psychoses, or bipolar … Schizophrenia, Catatonic/ 3. Schizophrenia, Disorganized/ 4. Schizophrenia, Paranoid/ 5.

13. First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/antipsychotics-adults/research
    August 14, 2012 - , schizophrenia-related psychoses, or bipolar disorder, with a focus on core illness symptoms, functional … Results We included 113 studies of schizophrenia (22 comparisons) and 11 studies of bipolar disorder … Core illness symptoms (global ratings and total scores) For schizophrenia, clozapine was more efficacious … Other outcomes For schizophrenia, few differences were found across comparisons and outcomes. … Antipsychotics in adults with schizophrenia: comparative effectiveness of first-generation versus second-generation

14. Antipsychotics-Adults Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_surveillance.pdf
    August 30, 2014 - SGAs for core illness symptoms in patients’ schizophrenia or schizophrenia-related psychoses and bipolar … For adults (age 18 to 64 years) with schizophrenia, schizophrenia-related psychoses, or bipolar disorder … Schizophrenia/Schizophrenia-Related SRC Literature Analysis: • No new research was found. … of patients with schizophrenia or schizophrenia-related psychoses … : Schizophrenia/Schizophrenia-Related Positive Symptoms No new research was found.

15. Antipsychotics-Adults Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
    August 01, 2012 - For adults (age 18 to 64 years) with schizophrenia, schizophrenia-related psychoses, or bipolar disorder … For adults (age 18 to 64 years) with schizophrenia, schizophrenia-related psychoses, or bipolar disorder … For adults (age 18 to 64 years) with schizophrenia, schizophrenia-related psychoses, or bipolar disorder … For adults (age 18 to 64 years) with schizophrenia, schizophrenia-related psychoses, or bipolar disorder … Overall, 113 studies examined schizophrenia or schizophrenia-related psychoses, 11 studies examined

16. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0024_06-09-2008.pdf
    January 01, 2008 - maker/payer) is interested in the comparative effectiveness of typical and atypical antipsychotics for schizophrenia … For adults with schizophrenia, related psychoses, or bipolar disorder (manic or depressive phases, … For adults experiencing a first episode of schizophrenia, do the atypical antipsychotic drugs differ … For adult patients with schizophrenia, related psychoses (including first episode), bipolar mania or … While there appears to be a large amount of comparative effectiveness research focused on schizophrenia

17. First and Second Generation Antipsychotics for Children and Young Adults-Comparative Effectiveness Review Update | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/antipsychotics-children-update/research-protocol
    December 07, 2015 - The SGA lurasidone was approved by the FDA in 2010 (for schizophrenia and later for bipolar depression … Two other SGAs were approved in 2015: brexpiprazole in July for schizophrenia and adjunctive treatment … Schizophrenia and schizophrenia-related psychosis Schizophrenia and schizophrenia-related psychosis … Scope and Key Questions Conditions of Interest Schizophrenia and schizophrenia-related psychoses, … ], presence of psychosis [disorders other than schizophrenia]).

18. Future Research Needs for First- and Second-Generation Antipsychotics for Children and Young Adults (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
    February 01, 2012 - ≥12 years Thioridazine Schizophrenia Adults and children Trifluoperazine Schizophrenia Adults and … Iloperidone Acute schizophrenia Adults Olanzapine Schizophrenia Bipolar disorder (manic/mixed … • Schizophrenia: For schizophrenia, SGAs were favored over placebo for clinical global impressions … ≥12 years Thioridazine Schizophrenia Adults and children Trifluoperazine Schizophrenia Adults and … KQ1 Schizophrenia 4.

19. Untitled (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
    December 04, 2015 - Schizophrenia!and!schizophreniaSchizophrenia and schizophrenia-related psychosis are grouped together because psychotic symptoms are … [schizophrenia],!presence!of!psychosis![disorders!other!than!schizophrenia]).! Interventions! Any! … schizophrenia!or!other!related!psychosis_!TD!=!Tic!disorders! ! ! ! ! ! … $exp$"Schizophrenia$and$Disorders$with$Psychotic$Features"/$ 21.$Schizophrenia,$Childhood/$ 22.

20. Antipsychotics-Children-Surveillance-150120 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-surveillance-150120.pdf
    October 01, 2014 - • Schizophrenia and schizophrenia-related psychoses, including schizoaffective disorder and drug-induced … or schizophrenia-related psychosis1. … • Schizophrenia and schizophrenia-related psychoses, including schizoaffective disorder and drug- … or schizophrenia-related psychosis. … or schizophrenia- related psychosis.