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effectivehealthcare.ahrq.gov/products/health-outcomes-competing-risks/abstract
February 11, 2010 - Developing Methods to Assess Health Outcomes in the Presence of Competing Risks for Effectiveness Research
Research Report February 11, 2010
Findings from this study were published in the following journal articles.
1. Weiss CO, Segal JB, Varadhan R. Assessing the applicability of trial evidence to a…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-translation-c-diff-treatment-clinical-pathway.pdf
November 01, 2019 - first recurrence, and multiple
recurrent) and further organized within each panel according to CDI scenario … likelihood, with the
least likely scenario (i.e. fulminant) listed last. … collapsed to minimize
visual complexity and facilitate quick location of the appropriate clinical scenario … Preferred orders within each
clinical scenario would be selected by default to reduce click requirements … As part of developing the CDI treatment
pathway, all likely patient scenario combinations (i.e. treatment
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/what-is-the-comparative-effectiveness-of-various-local-treatments-for-1-unresectable-liver-metastases-and-2-unresectable-localized-hepatocellular-carcinoma-hcc-does-the-comparative-effectiveness-vary-when-lesions-are-unresect
January 07, 2011 - This clinical scenario occurs frequently in patients with colorectal cancer.
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effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
January 01, 2013 - Study Size and Power Calculations in Randomized Controlled Trials (3 of 3)
Scenario Effect of Interest
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - Modifications to the data collection guidelines and additional training could be
undertaken in this scenario … of the study findings.31
Recommended Sensitivity Analyses
In addition to the above approaches, “scenario-based … identify “worst case” scenarios for the missing data: for
missing outcomes, one such “worst case” scenario … Such
scenario-based approaches can help set boundaries on causal effect size in ways that are useful … However, since scenario-based analyses are by their nature
specific to the data and situation under
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - Modifications to the data collection guidelines and additional training could be
undertaken in this scenario … of the study findings.31
Recommended Sensitivity Analyses
In addition to the above approaches, “scenario-based … identify “worst case” scenarios for the missing data: for
missing outcomes, one such “worst case” scenario … Such
scenario-based approaches can help set boundaries on causal effect size in ways that are useful … However, since scenario-based analyses are by their nature
specific to the data and situation under
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effectivehealthcare.ahrq.gov/products/survival-quality/research
April 12, 2013 - Progression-Free Survival: What Does It Mean for Psychological Well-Being or Quality of Life?
Research Report April 12, 2013 Web Version [NLM Site] Download Main Document PDF 511 KB
People using assistive technology may not be able to fully access information in these files. For additional assistance, p…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
January 01, 2009 - Study 1
Study 2
Study 3
Study 4
Higher Age
Lower Age
Study 4
Study 1
Study 3
Study 2
Scenario … 1
Scenario 2
Which Series of Studies Has an Applicability Issue? … In scenario 1, the studies are clustered around the higher age range. … In contrast, the studies in scenario 2 are dispersed across the continuum of age, which provides greater
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-diagnosis-disposition-160727.pdf
February 24, 2016 - evidence supporting each diagnostic test
(or the lack of evidence) were described
separately for each scenario … Clearly delineate each clinical scenario
that your report covers. 2. … Then, for each
scenario, review the evidence for the
additive diagnostic value of laboratory
tests
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effectivehealthcare.ahrq.gov/sites/default/files/mcda_webinar_transcript2.pdf
August 27, 2012 - For instance, if you present Thai food for a number of
times in this scenario and the respondent takes … realistic compared to
conjoint because in the real world life we make a decision
based on a whole scenario … You offer a scenario, a real life, a realistic
scenario, whereas, in MCDA you have decomposed scenarios
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effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
January 01, 2009 - Study 1
Study 2
Study 3
Study 4
Higher Age
Lower Age
Study 4
Study 1
Study 3
Study 2
Scenario … 1
Scenario 2
Which Series of Studies Has an Applicability Issue? … In scenario 1, the studies are clustered around the higher age range. … In contrast, the studies in scenario 2 are dispersed across the continuum of age, which provides greater
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
December 11, 2012 - Contemporary practice of this clinical
scenario is somewhat mixed with a segment of practitioners currently … Imaging for this scenario should not be
performed. It will only increase health care cost. … The only scenario in which imaging may be applicable is with a positive
MIS and a negative diagnostic … In this scenario, a through
evaluation of the retroperitoneum should be undertaken with MRA. … In a best
case scenario, this is an adequate proxy
outcome.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-genetic_methods.pdf
July 01, 2012 - It is important to have a clear definition of the clinical scenario and analytic framework when
evaluating … In this
scenario, investigators should determine the added value of testing for polymorphisms of
chromosome … key questions which, taken together, provide an example of a well defined
predictive genetic test scenario … A clear definition of the clinical scenario and an analytic framework is important when
evaluating any
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effectivehealthcare.ahrq.gov/products/angina-heart-attack-treatments/research
November 04, 2013 - Current Page Topic Timeline Oct. 25, 2011 Topic Initiated Dec. 13, 2012 Research Protocol Nov. 4, 2013 Systematic Review Feb. 13, 2014 Disposition of Comments Report Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non–ST Elevation Myocardial Infarction
Systematic Review Archived November 4, 2013 Web …
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effectivehealthcare.ahrq.gov/sites/default/files/suppl-1-user-guide-to-ocer_130129.pdf
January 01, 2011 - Improving Characterization of Study Populations: The Identification Problem
In a given empirical scenario … treated and untreated patients, and
the RA estimate of ATT would be biased
(which is distinct from scenario
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effectivehealthcare.ahrq.gov/sites/default/files/ch_9-user-guide-to-ocer_130129.pdf
September 21, 2012 - Example study size table for an RCT comparing the risk of death for
two alternative therapies*
Scenario
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effectivehealthcare.ahrq.gov/sites/default/files/facilitation-webcast-slides.pptx
June 13, 2013 - Community Forum
Community Forum
Community Forum
However, in conducting a deliberative session, the scenario … Rather than getting people’s reactions to messages (as in the focus group), this same scenario is now
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
February 01, 2012 - The first scenario is a case of low sensitivity (44 percent) and high
specificity (85 percent), which … body mass index,
reported snoring, and reported cessation of breathing during sleep.10 The second scenario … prediction questionnaire score and oximetry (sensitivity 83 percent,
specificity 95 percent).11 The third scenario … prevalence of 10 percent and an allowed variance of 10 percent in both sensitivity and
specificity
Scenario … For example in scenario 1, since the prevalence is 10
percent, the number of people that you would have
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-executive-summary.pdf
September 01, 2023 - The
majority of studies did not include simulations to address uncertainty from the
input or scenario
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-binary-outcomes-evaluation_research.pdf
March 11, 2013 - RCTs if
K>14); and
5. reporting actual data rather than sensitivity analyses (such as “worst case scenario … 11
Generation of Random Data
For each scenario we generated 500 random sets of studies on two correlated … for outcomes that have an is-subset-of relationship) explain the generation of simulation
data for scenario … difference between the
true (simulated) mean
and its estimate across
the 500 simulation
replicates in scenario … difference
between the true
(simulated) mean and its
estimate across the 500
simulation replicates in
scenario