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1. Evidence Summary: Syphilis Infection in Nonpregnant Adults and Adolescents: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-nonpregnant-adults-and-adolescents
   June 07, 2016 - All 4 samples that tested positive were positive with both testing methods. … : 3,092,938 RPR screening samples: 2,055,913 EIA screening samples: 1,037,025 August 2005 … submitted as blood donor screening (0.46% of RPR screening samples) (1.98% of EIA screening samples) … 0.59% of samples screened positive, and 0.46% of samples were confirmed positive 2.24% of samples … These samples represented 1 case of newly diagnosed neurosyphilis, and 3 patients whose serum samples

2. Archived: Evidence Summary: Syphilis Infection in Nonpregnant Adults and Adolescents: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-nonpregnant-adults-and-adolescents-june-2016
   June 07, 2016 - All 4 samples that tested positive were positive with both testing methods. … : 3,092,938 RPR screening samples: 2,055,913 EIA screening samples: 1,037,025 August 2005 … submitted as blood donor screening (0.46% of RPR screening samples) (1.98% of EIA screening samples) … 0.59% of samples screened positive, and 0.46% of samples were confirmed positive 2.24% of samples … These samples represented 1 case of newly diagnosed neurosyphilis, and 3 patients whose serum samples

3. Screening for Syphilis: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/TzddJozNQQZYmTohr64wMz
   June 07, 2016 - : 3 092 938 RPR screening samples: 2 055 913 EIA screening samples: 1 037 025 August 2005-July 2008 … submitted as blood donor screening (0.46% of RPR screening samples) (1.98% of EIA screening samples) … 0.59% of samples screened positive, and 0.46% of samples were confirmed positive 2.24% of samples … These samples represented 1 case of newly diagnosed neurosyphilis, and 3 patients whose serum samples … Fifteen of 1000 (1.5%) samples tested positive by MFI screening; 11/15 samples would not have been detected

4. Evidence Summary: Syphilis Infection in Pregnant Women: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/syphilis-infection-in-pregnancy-screening
   September 04, 2018 - false-negative response from high antibody titer) with rapid plasma reagin screening using undiluted samples … Reflex testing with FTA-ABS; recombinant IgG and IgM immunoblot used for confirmation of discordant samples … using serum diluted to 1:32 Reflex testing of TPPA+ samples with CIA NR 4/139 (2.9) (prozone … Reflex testing with FTA-ABS; recombinant IgG and IgM immunoblot used for confirmation of discordant samples … not applicable; NR, not reported; RPR, rapid plasma reagin; S/CO, ratio of optical density value of samples

5. Draft Research Plan: Cervical Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/cervical-cancer-screening-adults-adolescents
   October 28, 2021 - What is the test accuracy of and adherence to self-collected high-risk HPV vaginal samples? … In combination with cytology (cotesting) Mode of collection: Self- or clinician-collected hrHPV samples … sexually transmitted infection clinics, family planning clinics), or any setting for self-collection of samples

6. Evidence Summary: Chlamydia and Gonorrhea: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/chlamydia-and-gonorrhea-screening
   September 14, 2021 - Sensitivity of gonococcal testing was 89% or greater for all anatomical samples. … samples. 29 , 34 An additional study reported sensitivities of 56% for clinician-collected samples … and 52% for self-collected samples using a different study methodology. 37 One study compared clinician … - and self-collected vaginal samples for diagnosis of gonorrhea infection in females (eTable 8 in the … The “3 in 1” study: pooling self-taken pharyngeal, urethral, and rectal samples into a single sample

7. Final Research Plan: Cervical Cancer: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cervical-cancer-screening-adults-adolescents
   March 17, 2022 - What is the test accuracy of and adherence to self-collected high-risk HPV vaginal samples? … Specimen type: Cervical, vaginal, or urine Mode of collection: Self- or clinician-collected hrHPV samples … sexually transmitted infection clinics, or family planning clinics), or any setting for self-collection of samples

8. Screening for Syphilis Infection in Pregnant Women: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/9Tse2TwVFQgYb-aNCq4Ngv
   September 04, 2018 - false-negative response from high antibody titer) with rapid plasma reagin screening using undiluted samples … ARCHITECTa Index ≥1.0 Reflex testing with FTA-ABS; immunoblot used for confirmation of discordant samples … Reflex testing with FTA-ABS; recombinant IgG and IgM immunoblot used for confirmation of discordant samples … using serum diluted to 1:32 Reflex testing of TPPA+ samples with CIA NR 4/139 (2.9) (prozone phenomenon … ARCHITECTa Index ≥1.0; Reflex testing with FTA-ABS; immunoblot used for confirmation of discordant samples

9. Screening for Chlamydial and Gonococcal Infections: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/k-btyK4W2-v9KnemTK8WDx
   September 14, 2021 - Sensitivity of gonococcal testing was 89% or greater for all anatomical samples. … In 2 studies, sensitivity was 90% to 100% for clinician-collected samples and 90% to 98% for self- … collected samples.29,34 An additional study reported sensitivities of 56% for clinician-collected samples … False-positive rates in studies that compared self-collected and clinician-collected samples ranged … https://jama.com https://Supplement).29 https://methodology.37 https://samples.29 https://Supplement)

10. Clinical Summary: Screening for Elevated Blood Lead Levels in Children and Pregnant Women (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/QTqVDfsBVr4hhQW6ByuDGT
    April 09, 2019 - Patients with positive screening results from capillary blood samples should have confirmatory venous

11. Final Evidence Review: Testicular Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review96/testicular-cancer-screening
    September 15, 2010 - Plasma samples from 25 patients with testicular cancer were compared with samples from 24 patients with … designed polymerase chain reaction primer Unmethylated XIST DNA was found in 16 of 25 plasma samples … in men with testicular germ-cell tumors; none of the plasma samples in the comparison groups contained

12. Screening for Breast Cancer: An Update for the U.S. Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZcuLSXJZXLz9Y2LECTWqVJ
    November 01, 2009 - These data draw from community samples that are representative of the larger, national population and … None of these studies provide estimates specific to U.S. samples. … # Clear samples from the previous burn-in samplesClear(“*”) # Keep MCMC samples of parameters alpha … , beta, and sigma samplesSet(“alpha”) samplesSet(“beta”) samplesSet(“sigma”) # Thin samples so only … # Define R function; it will be used a number of times brugs.nodesummary �- function(x, name) { Samples

13. Archived: Final Evidence Summary: Breast Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary9/breast-cancer-screening-2009
    November 15, 2009 - # Clear samples from the previous burn-in samplesClear("*") # Keep MCMC samples of parameters … alpha, beta, and sigma samplesSet("alpha") samplesSet("beta") samplesSet("sigma") # Thin samples … <- samplesHistory("*", thin=samplesGetThin(), plot=FALSE) After the model was estimated and the samples … # Assign parameter samples to separate R vectors alpha <- as.vector(brugs.nodes$alpha) beta … rate1 / rate2 rd <- rate1 - rate2 nns <- n / (rate2 - rate1) From the 1000 thinned posterior samples

14. Draft Recommendation: Cervical Cancer: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/cervical-cancer-screening-adults-adolescents
    December 10, 2024 - Agreement between self-collected vaginal and clinician-collected cervical samples was high, with similar … proportions screening positive. 1 The pooled absolute sensitivity of self-collected samples to detect … The relative accuracy of self-collected vaginal samples to detect CIN2+ compared with the accuracy of … clinician-collected samples was high (relative sensitivity, 0.94 to 0.99; relative specificity, 0.98 … Performance of human papillomavirus testing on self-collected versus clinician-collected samples for

15. Screening for Testicular Cancer: An Evidence Review for the U.S. Preventive Services Task Force (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/677cVB3_YRhoEd3qakdjuS
    September 01, 2010 - Plasma samples from 25 patients with testicular cancer were compared with samples from 24 patients with … unmethylated was found in 16 of 25 designed to DNA may be a 24 men with other (abnormal) XIST plasma samples … screening test healthy patients polymerase chain none of the plasma in asymptomatic reaction primer samples

16. Screening for Lipid Disorders in Children: Recommendation Statement (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/BwAo_shwmJLSRguyWxaXpP
    July 01, 2007 - screen for dyslipidemia, the preferred screening tests are TC and HDL-C on nonfasting or fasting samples … ; calculating LDL-C requires fasting samples. … Accuracy of Screening Tests TC and HDL-C can be measured on nonfasting venous or capillary blood samples … , LDL-C measurement requires fasting samples, and direct LDL-C can be measured on nonfasting venous … samples.

17. Archived: Lipid Disorders in Children: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening-2007
    July 15, 2007 - to screen for dyslipidemia, the preferred screening tests are TC and HDL-C on nonfasting or fasting samples … ; calculating LDL-C requires fasting samples. … Accuracy of Screening Tests TC and HDL-C can be measured on nonfasting venous or capillary blood samples … , LDL-C requires fasting samples, and direct LDL-C can be measured on nonfasting venous samples.

18. Archived: Evidence Summary: Drug Use, Illicit: Primary Care Interventions for Children and Adolescents | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary24/drug-use-illicit-primary-care-interventions-for-children-and-adolescents-march-2014
    March 11, 2014 - In general, the prevalence and frequency of baseline drug use were relatively low in all of the samples … The samples within each study varied in size and demographic factors. … In both samples, approximately 75% of the girls were nonwhite. … These studies used 2 distinct samples that occurred within the same time frame. (Schinke SP. … Given the low prevalence of drug use among the samples, we can presume that most youths were not using

19. Draft Research Plan: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-testing
    January 18, 2024 - BRCA1/2 mutations All KQs: Other interventions KQ 3c: BRCA1/2 testing of pathology or tissue samples … ; direct to consumer laboratory testing or samples; and non-FDA approved tests Comparisons KQ

20. Final Research Plan: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-testing
    April 11, 2024 - BRCA1/2 mutations All KQs: Other interventions KQ 3c: BRCA1/2 testing of pathology or tissue samples … ; direct to consumer laboratory testing or samples; non-FDA approved tests Comparisons KQ 1: