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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-future_research.pdf
February 01, 2012 - and many of the research questions (e.g., between-drug
effectiveness comparisons) may require large samples … would require about 29 people per group (the sample size listed for an
effect size of 0.75 and two samples … comparisons of means14
(two-tailed test, α=.05, power=.80)
Effect Size One Sample (Paired) Two Samples … that
difference would require a much larger sample size, approximately 393 per group (ES, 0.20, two
samples … Inference for proportions:
comparing two independent samples
[Computer software].
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - It is not clear why collection of samples at baseline in a
cohort study would introduce “null bias”. … If anything,
exposure ascertainment using samples obtained at
baseline is the preferred approach. … Citrated whole blood samples for measurement by LTA are
prepared by first centrifuging the sample to … Direct, unprocessed citrated whole
blood samples are spiked onto a needle in the sample port of
the … We note that studies describing analytic
performance using blood samples from healthy normal donors
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-creating-efficiencies-extraction-data.pdf
August 01, 2021 - Methods Research Report: Creating Efficiencies in the Extraction of Data From Randomized Trials
Methods Research Report
Creating Efficiencies in the Extraction of Data From
Randomized Trials: A Prospective Evaluation of a
Machine Learning and Text Mining Tool
Methods Research Report
Creating Efficie…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
March 01, 2013 - reviews, meta-
analysis, and synthesis in general are that the circumstances of each study and the samples … studies
investigating the drug, and the thickness of each edge corresponds to the total number of samples … physicians in providing clinical
understanding.
35 using 10000
Markov chain Monte Carlo (MCMC) samples … trace plots, we
decided to use only a single MCMC chain, run for 5000 burn-in and 10000 production samples … number of studies investigating the drug, and the thickness of each edge implies the total number of samples
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
July 01, 2012 - Systematic Bias Description
Population
Spectrum effect
Tests may perform differently in various samples
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - health records, both paper and electronic, clinical visits,
and, in some cases, collect biological samples … over registry
data or biospecimens to advocacy organizations to act as the stewards of these data and samples … At the present time it contains more than 30,000 samples of a variety of
tissue types from DNA to cell … confidentiality (see section “Participant Privacy and Confidentiality”), ownership of data and any
tissue samples
-
effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - Identifies all incident cases that develop an outcome and compares exposure history to controls
Samples
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-executive-summ.pdf
January 01, 2023 - Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2023 Update of the Evidence Base for the PTSD Trials Standardized Data Repository
Systematic Review
Pharmacologic and Nonpharmacologic Treatments
for Posttraumatic Stress Disorder: 2023 Update of
the Evidence Base for the PTSD …
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-5-final-report-update-2024-executive-summ.pdf
January 01, 2024 - Executive Summary_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2024 Update of the Evidence Base for the PTSD Trials Standardized Data Repository
Systematic Review
Pharmacologic and Nonpharmacologic
Treatments for Posttraumatic Stress Disorder:
2024 Update of the Evidence …
-
effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
January 01, 2013 - Slide 1
Study Size Planning for Observational Comparative Effectiveness Research
Prepared for:
Agency for Healthcare Research and Quality (AHRQ)
www.ahrq.gov
Study Size Planning for Observational Comparative Effectiveness Research
This slide set is based on a user guide titled Developing a Protocol for Observation…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
January 01, 2019 - Auxiliary material was available, including samples of statements describing future
research needs … management decisions: past, present, and future
2004 Risk Anal
15356229 Forecasting the number of soil samples
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveillance-report-2.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author,
Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-To-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-opioid-chronic-pain-surveill-report-1.xlsx
January 01, 2021 - Table E-1. RCT QA
Table E-1. RCT quality assessment
Author,
Year Randomization Adequate? Allocation Concealment Adequate? Groups Similar at Baseline? Outcome Assessors Masked? Care Provider Masked? Patient Masked? Intention-to-Treat (ITT) Analysis Acceptable Levels of Overall Attrition and Between-Group Differences…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
February 01, 2018 - Quantitative Synthesis: Chapter 2. Presenting Different Effects for Different Data Types
Quantitative Synthesis
Chapter 2. Presenting Different Effects
for Different Data Types
Prepared for:
The Agency for Healthcare Research and Quality (AHRQ)
Training Modules for Systematic Reviews Methods Guide
www.ahrq.gov
…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-e.xlsx
January 01, 2023 - Title
Appendix E. Risk of Bias Assessments
Table E-1. RCTs - Risk of Bias
Table E-1. Risk of bias assessments for randomized controlled trials (RCTs) evaluating fusion procedures for degenerative spondylolisthesis (Key Questions [KQs] 1-4) and nonsurgical/select interventions for chronic low…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-protein-intake-protocol-amendment.pdf
November 29, 2023 - The Effect of Protein Intake on Health
Evidence-based Practice Center Systematic Review Protocol
Project Title: The Effect of Protein Intake on Health
Publication Date: June 2, 2023
Amendment Date(s): November 17, 2023, November 28, 2023, November 29, 2023
(Amendments Details–see Section VI)
I. Ba…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-frameworks.ppt
June 01, 2012 - PowerPoint Presentation
Developing the Topic and Structuring
Systematic Reviews of Medical Tests:
Utility of PICOTS,
Analytic Frameworks, Decision Trees,
and Other Frameworks
Prepared for:
The Agency for Healthcare Research and Quality (AHRQ)
Training Modules for Medical Test Reviews Methods Guide
www.ahrq.gov
De…
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-frameworks.ppt
June 01, 2012 - PowerPoint Presentation
Developing the Topic and Structuring
Systematic Reviews of Medical Tests:
Utility of PICOTS,
Analytic Frameworks, Decision Trees,
and Other Frameworks
Prepared for:
The Agency for Healthcare Research and Quality (AHRQ)
Training Modules for Medical Test Reviews Methods Guide
www.ahrq.gov
De…
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
January 01, 2011 - 21
Abstract
The choice of study design often has profound consequences for the causal interpretation of study
results. The objective of this chapter is to provide an overview of various study design options for
nonexperimental comparative effectiveness research (CER), with their relative advantages and limitations,…
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - For example, some participants may have missing laboratory values
because a batch of lab samples was … Additionally, while randomized clinical trials (RCTs)
often limit their samples to a narrow and often