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  1. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - Investigators noted that use of the Cytosponge, which samples cells along a much broader section of … more useful diagnostic information than traditional endoscopic biopsies that collect discrete tissue samples … than traditional endoscopic biopsy.10,11 Researchers performed whole-genome sequencing on paired samples … esophageal adenocarcinoma (EAC) taken from 23 patients at a single time point and compared them to 73 samples … more useful diagnostic information than traditional endoscopic biopsies that collect discrete tissue samples
  2. effectivehealthcare-admin.ahrq.gov/products/radiation-brain-metastases/protocol
    June 01, 2021 - in the brain resulting from non-small cell lung cancer, breast cancer, or melanoma Study samples … patients with cancer from other origins or primary brain tumors (e.g., glioblastomas) and pediatric samples … account that frequentist approaches are problematic for rare adverse events (rare events require large samples … assessment will take the developing technology in the field of radiation therapy into account, review the samples … In addition, we will critically review the samples included in existing trials to determine how well
  3. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
    October 10, 2019 - metastases in the brain resulting from non- small cell lung cancer, breast cancer, or melanoma • Study samples … patients with cancer from other origins or primary brain tumors (e.g., glioblastomas) and pediatric samples … account that frequentist approaches are problematic for rare adverse events (rare events require large samples … assessment will take the developing technology in the field of radiation therapy into account, review the samples … In addition, we will critically review the samples included in existing trials to determine how well
  4. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
    June 23, 2014 - Includes pregnant women Pediatric bipolar patients Studies with samples of greater than 25% identified … diagnosis.17 Therefore, a detailed understanding of the diagnostic processes used to establish study samples … One can use RCT and controlled cohort data, but they generally have small samples, short follow-ups. … Assessing Applicability Bipolar research generally draws from highly defined populations, resulting in samples
  5. effectivehealthcare-admin.ahrq.gov/products/antiplatelet-treatment/research-protocol
    December 01, 2019 - , evidence can be obtained by repurposing completed randomized controlled trials for which baseline samples … In such cases, one can analyze all the samples (e.g., samples from the clopidogrel group and from the … comparisons (e.g., inter-laboratory agreement, measurement reproducibility) Proportion of nonevaluable samples
  6. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-disposition-comments.pdf
    June 16, 2022 - Results from these non-representative study samples cannot be generalized to all women. … substance abuse, or women attending an academic health center.” …”Results from these select study samples … Discussion and Conclusions However, in the results, there is no mention as to whether the study samples … in restricting access to technology to specific clinics/settings – so expanding to community based samples
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
    May 14, 2020 - The differences in rates of assisted delivery between the Friedman and the CSL samples is another important … consider adding more details regarding differences in intervention rates between the Friedman and CSL samples … practice patterns between the 1950s-70’s and the early 2000’s, by detailing how much all of these samples … explicitly made that we do not have US research about normal vs abnormal labor progress that includes samples
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-224-depression-children-comments.pdf
    April 10, 2020 - monotherapy may not match combined therapy for those without ADHD but these findings arise from small samples … monotherapy may not match combined therapy for those without ADHD but these findings arise from small samples … expect fewer studies, and prior reviews of the literature suggest that studies that focus on younger samples … defined by study authors [typically age 10 or 11 years or younger], and mixed adolescent and child samples
  9. effectivehealthcare-admin.ahrq.gov/products/c-diff-infections/research-protocol
    December 01, 2019 - For example, a recent study isolated C. difficile spores from air samples in a United Kingdom hospital … Stool samples must be from patients with suspected C. difficile infection.
  10. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/appendix-table-B-1-observational-studies.xlsx
    March 20, 2021 - Ab+ on enrollment or Ab+ from previous clinical lab samples, with or w/o a previous PCR+; Ab- on enrollment … locally validated assays" NR Possible reinfection defined as a positive cohort participant with two PCR+ samples
  11. effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-women-in-the-postpartum-period-what-is-the-effectiveness-and-safety-of-screening-and-treatment-for-depression-please-use-the-uspstf-framework-which-considers-not-only-screening-but-followup-treatment-and-management-the-t
    November 01, 2017 - could not distinguish between major and minor depression, and suggested that future studies have larger samples
  12. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
    February 01, 2013 - Prospective cohort studies with large samples may ES-7 be preferred to small RCTs, yet no … Investigators need to conduct power calculations to recruit sufficient stratified samples. … Prospective cohort studies with large samples may be preferred to small RCTs, yet no well designed … Enables recruitment of larger samples. … Resource use, size and duration Likely necessary to recruit large samples because marginal clinically
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
    February 01, 2012 - Itzkowitz (2008), cases subjects were subjects with CRC diagnosed at colonoscopy and their fecal samples … However, stool samples taken after colonoscopy is problematic as colonoscopies often biopsy or remove … , rather than stool samples, and methyl-BEAMing does not appear to be used in the assay evaluated by … , rather than stool samples, and methyl-BEAMing does not appear to be used in the assay evaluated by … However, stool samples taken after colonoscopy is problematic as colonoscopies often biopsy or remove
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
    November 22, 2011 - evidence can be obtained by repurposing completed randomized controlled trials for which baseline samples … In such cases, one can analyze all the samples (e.g., samples from the clopidogrel group and from the … www.effectivehealthcare.ahrq.gov Published Online: November 22, 2011 8 o Proportion of nonevaluable samples
  15. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_executive.pdf
    August 01, 2012 - They used archived laboratory samples that had been obtained for SPEP or UPEP. … In several studies, study samples were obtained from large repositories in laboratories, populations … The possibility of multiple samples from the same patient being analyzed without accounting for nonindependence … Selection bias could occur if study samples from large laboratory repositories are selected on the basis
  16. effectivehealthcare-admin.ahrq.gov/products/ptsd-adults-trauma-interventions/research-protocol
    December 01, 2019 - the frequency of these events may vary by the group studied, for example, civilian versus noncivilian samples … conducted in the 1990s attempted to identify and describe the prevalence of traumatic events in nonclinical samples
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/data-extraction.ppt
    January 01, 2009 - Samples of Final Data Extraction Forms (Evidence Tables) For evidence reports or technology assessments … Samples of Final Data Extraction Forms (Evidence Tables) Reference: Trikalinos TA, Ip S, Raman G, et
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/c-diff-infections_research-protocol.pdf
    May 24, 2010 - For example, a recent study isolated C. difficile spores from air samples in a United Kingdom hospital … Stool samples must be from patients with suspected C. difficile infection.
  19. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colon-cancer-gene-profiling_disposition-comments.pdf
    December 14, 2012 - Data concerning the validation of the Oncotype DX® Colon Cancer assay with samples from the QUASAR … USEFULLY separated groups by likelihood of benefit from the regimen used in the RCT that provided samples … The other tests described in your review have been based on studies in convenience samples, and have
  20. effectivehealthcare-admin.ahrq.gov/sites/default/files/celiac-disease_disposition-comments.pdf
    January 28, 2016 - referred for endoscopy where they undergo biopsies to confirm celiac disease, and then their serum samples … the group with seropositive The studies you describe are case-control studies where stored blood samples … —that do compare the performance of testing and the accuracy in standardized serum samples.

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