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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/tonsillectomy_research-protocol.pdf
    February 10, 2016 - We  scanned  a  random  sample  of  100   non-­English  abstracts  retrieved  by  our  MEDLINE  search … We  will,  however,  re-­assess  a  sample  of  non-­English   studies  as  we  update  our  MEDLINE   … larger  observational  studies   of  harms  of  tonsillectomy  in  the  literature,  and  the  larger  sample …  age  distribution,  demographic  attributes,  and  the  underlying   indications  in  the  study  sample … established  concepts  of  the  quantity  of  evidence  (e.g.,   numbers  of  studies,  aggregate  ending-­sample
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ptsd-adult-treatment_research-protocol.pdf
    December 20, 2011 - In addition, we will include nonrandomized controlled trials of any sample size, prospective cohort … studies with an eligible comparison group with a sample size of at least 500, and case-control studies … with a sample size of at least 500. … We will not include observational studies with a sample size of less than 500 or for other KQs due … For KQ 6, we have chosen a sample size cutoff Source: www.effectivehealthcare.ahrq.gov Published
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_research-protocol.pdf
    April 01, 2013 - risk of bias, retrospective studies must have used consecutive enrollment or enrollment of a random sample … percent confidence interval (95% CI) will be calculated from reported means, standard deviations, and sample … adverse-event outcomes with ranges according to treatment option, tumor characteristics, and group sample … We will summarize the results of individual studies with relation to sample size and the 95% CI. … completion dates but have not been published within 2 years of completion • Whether studies with smaller sample
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_research-protocol.pdf
    April 02, 2015 - • Minimum sample sizes o All outcomes: To be determined § We will aim for a minimum of about … outcomes • We expect to include at least 50 RCTs • We will choose RCTs based on a combination of sample … • We expect to include at least 50 RCTs • We will choose RCTs based on a combination of sample … exposures, or biomarker status (and comparators) analyzed; outcome definitions; enrolled and analyzed sample … These included descriptions of the study design, sample size intervention(s), follow-up duration, outcomes
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_surveillance.pdf
    June 01, 2012 - The sample size of the randomized trials ranged from 82 11 to 806 7. … The sample size of the observational studies ranged from 40 13 to 149 5 participants. … The findings from an RCT with smaller sample size (n=82) favored the revascularization group: Medical … [sample size =55] The survival curves were nearly identical for the two groups over 42 months. … Or 2) a trial not published in the above top 5 journals but have a sample size of at least triple the
  6. effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-child-adolesc-mental-health-grand-rounds.pptx
    May 22, 2025 - Brief Assessment Tools Characteristic Range Across Studies Risk of Bias 1 low, 9 moderate, 8 high Sample … 46 Extra Slides: Flow Diagram 47 Extra Slides: KQ1 RoB Study Was a consecutive or random sample … CAMS Predominantly white but 40% male sample. Not superior to TAU. … DDP Female and White sample. Before-after study.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
    January 01, 2007 - restrictive patient eligibility or inadequate reporting; and limited power of studies due to small sample … Moderate Sample is representative of a relevant subgroup of the target population, but not the entire … Low Sample is representative of a narrow subgroup of subjects only, and is of limited applicability … N, minimum sample size; >=6 mo, minimum duration 6 months; >=1993, patients included had interventions … Studies ordered from longest to shortest duration of followup, then sample size. 22 Figure
  8. CERs Report cover (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-feature-treatment-future_research.pdf
    September 23, 2010 - Likely multicenter studies will be necessary to attain adequately powered sample sizes. … The sample size was limited by the Paperwork Reduction Act and Information Collections Policy (44 USC … Instead, we sought to minimize the burden by using a small sample size and informal discussions via … Sample size est. was 220; 300 envelopes were generated but only 210 enrolled: groups were unbalanced
  9. effectivehealthcare.ahrq.gov/sites/default/files/celiac-disease_disposition-comments.pdf
    January 28, 2016 - Commentator & Affiliation Section Comment Response of celiac disease and when a second blood sample
  10. effectivehealthcare.ahrq.gov/sites/default/files/manges.pdf
    May 29, 2025 - ENVIRONMENTAL PROTECTION AGENCY INNOVATIONS CONFERENCE -- ENVIRONMENTAL PROTECTION AGENCY SPEAKER: ELLEN MANGES, SENIOR ADVISOR, OFFICE OF SOLID WASTE AND EMERGENCY RESPONSE (OSWER) ENVIRONMENTAL PROTECTION AGENCY (EPA) MANGES: My name is Ellen Manges. I'm a senior advisor. I…
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/disparities-quality-improvement_research-protocol.pdf
    February 23, 2012 -  The minimum sample size for inclusion is 50 per study-intervention group. … information (e.g., minimum effect size, standard error), to inform a power calculation, the minimum sample … year of publication, study location (e.g., city, state) and time period, population description, sample
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
    December 01, 2010 - The form will be pilot tested on a sample of studies. … The form will be pilot tested on a sample of studies. … assessed by using the cohort Newcastle-Ottawa Scale.23 This scale includes seven items that assess sample … Each assessment form will be pilot tested on a sample of studies.
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
    January 01, 2013 - stakeholder participation, we were not able to collect a representative perspective from a larger sample … example, factors that affect the feasibility of conducting randomized controlled trials include the sample … Similar to RCT Sample size will need to be larger than experimental designs given heterogeneity … Sample size will need to be larger than randomized designs given heterogeneity of population and … stakeholder participation, we were not able to collect a representative perspective from a larger sample
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_disposition-comments.pdf
    August 27, 2012 - See the “guidance” for CERs for some sample language, which ought to help. … You might even consider a new heading for Sample Size. … We have inserted a level two heading for “Sample Size”. … We have deleted the table footnote and added a section for “Sample Size”. … As noted by the authors, this was an estimate for minimum required sample size.
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharma-ptsd-update-summary.pdf
    November 01, 2020 - The majority of studies were conducted in the United States (62%), and most had sample sizes in the
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-depression-research-protocol-amended.pdf
    February 15, 2017 - Australia, New Zealand Study design • Original peer-reviewed data • KQ 1: Observational studies, sample … size ≥50 subjects • KQ 2: Randomized controlled trials (RCTs), sample size ≥20 subjects Editorials … Before they are used, abstraction form templates will be pilot-tested with a sample of included articles … methodological quality of individual studies, the spectrum of depressive disorders, and age of the sample … Influence of trial sample size on treatment effect estimates: meta-epidemiological study.
  17. effectivehealthcare.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-disposition-comments.pdf
    June 14, 2021 - If a study had 10 percent or fewer pediatric patients in the sample, we categorized the study as “adult … There are limitations in this manner, especially study sample size, but when attempting to answer questions
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
    June 01, 2022 - We did not conduct statistical or graphical methods for assessing for small sample effects (a potential
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
    September 01, 2013 - meta-analysis of normally distributed data compared with other linear weighting schemes (e.g., by sample … inadequate to answer such questions as which method minimizes statistical bias because in an empirical sample … The performance of tests of publication bias and other sample size effects in systematic reviews of
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/tinnitus_research-protocol.pdf
    February 22, 2012 - study characteristics (i.e., population characteristics, treatment interventions, study outcomes, sample … diagnostic accuracy outcomes, and the effect size for treatment monitoring; this domain is related to study sample … ☐ ☐ ☐ Was the sample size justified? … Study Attrition - The proportion of sample completing the study and providing outcome data is adequate … - Adequate study sample has complete data for prognostic factors.

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