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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
    March 01, 2013 - Although the use of a composite outcome as the primary outcome in a clinical trial can reduce sample … In meta-analysis, sample size is less of a concern than in clinical trials, and thus the motivation … Clinical Trials Composite outcomes can improve statistical efficiency, increasing power for a given sample … Recommendations Descriptive study information Include information for each study describing the sample … present tables or a graphical representation of the data (forest plot) including: The comparison type, sample
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-update_research-protocol.pdf
    September 20, 2013 - After reviewing a sample of relevant articles, the team will assess the data-collection forms from the … publication, study location (e.g., country, city, state) and time period, population description, sample … will use established concepts of the quantity of evidence (e.g., numbers of studies, aggregate ending-sample … Complementary and alternative medicine use in a large pediatric autism sample. … A sample table is shown below: Date Section Original Protocol Revised Protocol Rationale This should
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol.pdf
    September 13, 2024 - Forms will be pilot tested with a sample of included articles to ensure that all relevant data elements
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/structured-handoff-rapid-research.pdf
    January 01, 2025 - All titles and abstracts with lower predicted probability were rejected, but a 10 percent sample was … pre-post studies all scored well using the modified NIH Tool (except for 2 studies with very small sample … both pediatric and adult 32 hospitals 20 academic 12 communit y For clinical outcomes the sample … Was the sample size sufficiently large to provide confidence in the findings? … Was the sample size sufficiently large to provide confidence in the findings?
  5. Menopause Executive (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
    March 01, 2015 - trials may have not given the agent to women without a uterus yet reported an effect for the entire sample
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
    October 01, 2021 - relate to the limited ability to provide strong, reliable, estimates of effect due to: 1) inadequate sample … Important limitations include small sample sizes, lack of evidence for moderate and long-term use, and
  7. effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
    November 01, 2020 - However, sample sizes were small, followup was short term, most studies only used visual analog scales
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-executive-summary.pdf
    October 01, 2022 - information into evidence tables, including study design, country, funding source, study duration, sample
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
    September 08, 2011 -  Statistical analyses (statistical test/estimation results) Test used Summary measures Sample … selection of items proposed by Deeks et al. 13 to inform the USPSTF approach, as follows: o Was sample … o Did the whole sample or a random selection of the sample, receive verification using a reference
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/appendicitis_executive.pdf
    December 01, 2015 - We verified the data extraction and risk-of-bias assessment in a random sample of 368 noncomparative … Furthermore, multivariable models were often developed and evaluated in the same patient sample. … of diagnostic scores, multivariable models were often developed and evaluated in the same patient sample … Many had sample sizes that were too small to reliably detect small or moderate differences between … • In contrast to the RCTs, NRCSs of alternative testing strategies attained large sample sizes but
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
    April 30, 2014 - We have provided additional study design recommendations, particularly with respect to sample size … We have clarified that we were referring to the majority of studies when discussing small sample sizes … We have provided details about the sample size requirements for such a trial. … We believe that the required sample size is not prohibitive (even for a small size consortium) given … , pelvic abscess, etc.), and that the study will need to be stratified by anatomical segment, the sample
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
    January 01, 2010 - Source: www.effectivehealthcare.ahrq.gov Published Online: October 24, 2011 □ Summary measures □ Sample … Preventive Services Task Force,35 as follows: O Was sample definition and selection prospective
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
    June 23, 2014 - catalogue one-off studies of interventions (only one study examining a particular intervention) with low sample … The form will be tested by investigators using an initial sample of included studies and will be finalized
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
    June 01, 2023 - to be able to distinguish patient samples, including selection criteria for entering the research sample … criteria of the study and the included patients in the research 9 sample … introduced bias, taking into account, for example, whether the study enrolled a consecutive or random sample … When quantitative synthesis is not possible, sample size and assessment of variance within individual
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
    January 01, 2014 - However, the study sample is non-randomized and, therefore, subject to bias. … However, the study sample is non-randomized and, therefore, subject to bias. … Both studies were more than 20 years old, had small sample sizes, and found no benefit for systemic … Standards for Estimating Proper Sample Sizes Well-developed statistical methods for estimating the size … …for estimating proper sample sizes.
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-911-workforce-mental-health-protocol-amendment.pdf
    January 22, 2024 - We will not restrict by sample size or study quality. … Key Questions No sample size restriction For Key Question 1 for EMS populations, we will After … No sample size restriction will apply to studies of 911 populations. … Because KQ 1 is largely about epidemiology (incidence, prevalence, and severity), a sample size
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/single-group-studies_white-paper.pdf
    January 01, 2013 - authors planned to use single group studies, selection criteria for single group studies (minimum sample … However, this interpretation is limited by the small sample size. F Figure 2. … Finally, our empirical review was conducted among the small sample of CERs that had been prepared by … in the randomized two arm trial designs (though the two arm studies required a 2–4 fold increased sample
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pain-chronic_research-protocol.pdf
    July 28, 2010 - What was the sample size? 3. How many patients were lost to follow-up (or dropped out)? 4. … We will include studies of any sample size, any design (RCT, controlled clinical trial, uncontrolled … General study factors (design, sample size, country, funding source) Information related to Question
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
    September 15, 2008 - Sample Letter Excerpt (for Key Question 1 from CER#1) ............................................... … Sample Letter Excerpt (for Key Question 1 from CER#1) Conclusions from CER Executive Summary Is … Sample Letter Excerpt (for Key Question 1 from CER#1) Literature Searches FDA MedWatch and Canadian
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-protocol-2021_0.pdf
    January 01, 2021 - Diagnosis of acute stress disorder • Studies that do not specify criteria used to diagnose PTSD • Sample … studies are screened and determined to meet inclusion criteria, study design, year, setting, country, sample … Characteristics of included studies, such as number of publications by year, study sample size, proportion

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